CU20100137A7 - DERIVATIVES OF 19-NOR-STEROID THAT HAS A GROUP 15, 16-METHYLENE AND A RING OF 17, 17-SATURATED ESPIROLACTONE, ITS USE AND MEDICINES THAT UNDERSTAND - Google Patents
DERIVATIVES OF 19-NOR-STEROID THAT HAS A GROUP 15, 16-METHYLENE AND A RING OF 17, 17-SATURATED ESPIROLACTONE, ITS USE AND MEDICINES THAT UNDERSTANDInfo
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- CU20100137A7 CU20100137A7 CU20100137A CU20100137A CU20100137A7 CU 20100137 A7 CU20100137 A7 CU 20100137A7 CU 20100137 A CU20100137 A CU 20100137A CU 20100137 A CU20100137 A CU 20100137A CU 20100137 A7 CU20100137 A7 CU 20100137A7
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- hydrogen
- methylene
- group
- alkyl
- derivatives
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Los derivados de y-lactona del ácido 15alfa,16alfa-metilen-17-hidroxi-19-nor-17-pregna-4-en-3-ona-21-carboxílico de la presente invención poseen efectividad gestagénica. Tienen la fórmula química general I, en la cual Z se selecciona del grupo que comprende un átomo de oxígeno, dos átomos de hidrógeno, NOR y NNHSO2R, donde R es hidrógeno, alquilo-C1-C10, arilo o aralquilo-C7-C20, R4 es hidrógeno o halógeno; además, R6a, R6b forman juntos metileno o 1,2-etandiilo p R6a es hidrógeno y R6b se selecciona del grupo que comprende hidrógeno, alquilo-C1-C10, alquenilo-C2-C10 o alquinilo-C2-C10, y R7 se selecciona del grupo que comprende hidrógeno, alquilo-C1-C10, cicloalquilo-C3-C6, alquenilo-C2-C10 o alquinilo-C2-C10 o: R6a es hidrógeno y R6b y R7 juntos forman un enlace, un oxígeno o metileno, R18 representa hidrógeno o alquilo-C1-C3 y comprenden además sus solvatos, hidratos, estereoisómeros y sales.The y-lactone derivatives of 15alpha, 16alpha-methylene-17-hydroxy-19-nor-17-pregna-4-en-3-one-21-carboxylic acid of the present invention possess gestagenic effectiveness. They have the general chemical formula I, in which Z is selected from the group comprising an oxygen atom, two hydrogen atoms, NOR and NNHSO2R, where R is hydrogen, C1-C10 alkyl, aryl or aralkyl-C7-C20, R4 is hydrogen or halogen; in addition, R6a, R6b together form methylene or 1,2-ethanediyl p R6a is hydrogen and R6b is selected from the group comprising hydrogen, C1-C10 alkyl, C2-C10 alkenyl or C2-C10 alkynyl, and R7 is selected from the group comprising hydrogen, C1-C10 alkyl, C3-C6 cycloalkyl, C2-C10 alkenyl or C2-C10 alkynyl or: R6a is hydrogen and R6b and R7 together form a bond, an oxygen or methylene, R18 represents hydrogen or C1-C3 alkyl and further comprise its solvates, hydrates, stereoisomers and salts.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20100137A CU20100137A7 (en) | 2010-06-29 | 2010-06-29 | DERIVATIVES OF 19-NOR-STEROID THAT HAS A GROUP 15, 16-METHYLENE AND A RING OF 17, 17-SATURATED ESPIROLACTONE, ITS USE AND MEDICINES THAT UNDERSTAND |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20100137A CU20100137A7 (en) | 2010-06-29 | 2010-06-29 | DERIVATIVES OF 19-NOR-STEROID THAT HAS A GROUP 15, 16-METHYLENE AND A RING OF 17, 17-SATURATED ESPIROLACTONE, ITS USE AND MEDICINES THAT UNDERSTAND |
Publications (1)
Publication Number | Publication Date |
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CU20100137A7 true CU20100137A7 (en) | 2011-10-31 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU20100137A CU20100137A7 (en) | 2010-06-29 | 2010-06-29 | DERIVATIVES OF 19-NOR-STEROID THAT HAS A GROUP 15, 16-METHYLENE AND A RING OF 17, 17-SATURATED ESPIROLACTONE, ITS USE AND MEDICINES THAT UNDERSTAND |
Country Status (1)
Country | Link |
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CU (1) | CU20100137A7 (en) |
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2010
- 2010-06-29 CU CU20100137A patent/CU20100137A7/en unknown
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