CU20090081A7 -
CRYSTAL SALTS AND FORMS OF 2-METHYL-2- [4- (3-METHYL-2-OXO-8-QUINOLIN-3-IL-2,3-DIHYDRO-IMIDAZO- [4,5-C] -CHEMINOLIN- 1IL) -PENYL] -PROPIONITRILE
- Google Patents
CRYSTAL SALTS AND FORMS OF 2-METHYL-2- [4- (3-METHYL-2-OXO-8-QUINOLIN-3-IL-2,3-DIHYDRO-IMIDAZO- [4,5-C] -CHEMINOLIN- 1IL) -PENYL] -PROPIONITRILE
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CU20090081A7
CU20090081A7CU20090081ACU20090081ACU20090081A7CU 20090081 A7CU20090081 A7CU 20090081A7CU 20090081 ACU20090081 ACU 20090081ACU 20090081 ACU20090081 ACU 20090081ACU 20090081 A7CU20090081 A7CU 20090081A7
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La invención se refiere a formas cristalinas particulares del 2-metil-2-[4-(3-metil-2-oxo-8-quinolin-3-il-2,3-dihidro-imidazol-[4,5-c]-quinolin-1-il)-fenil]-propionitrilo, sus hidratos y solvatos, sus sales e hidratos y solvatos de sus sales, a ciertos procesos para su preparación, a composiciones farmacéuticas que contienen estas formas cristalinas, y a su uso en métodos de diagnóstico o, de preferencia, para el tratamiento terapéutico de animales de sangre caliente, en especial seres humanos, y a su uso como un intermediario o para la preparación de las preparaciones farmacéuticas para utilizarse en métodos de diagnóstico o, de preferencia, para el tratamiento terapéutico de animales de sangre caliente, en especial seres humanos.The invention relates to particular crystalline forms of 2-methyl-2- [4- (3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazol- [4,5-c] -quinolin-1-yl) -phenyl] -propionitrile, its hydrates and solvates, its salts and hydrates and solvates of its salts, certain processes for its preparation, pharmaceutical compositions containing these crystalline forms, and their use in methods of diagnosis or, preferably, for the therapeutic treatment of warm-blooded animals, especially humans, and for use as an intermediary or for the preparation of pharmaceutical preparations for use in diagnostic methods or, preferably, for therapeutic treatment of warm-blooded animals, especially humans.
CU20090081A2009-05-132009-05-13
CRYSTAL SALTS AND FORMS OF 2-METHYL-2- [4- (3-METHYL-2-OXO-8-QUINOLIN-3-IL-2,3-DIHYDRO-IMIDAZO- [4,5-C] -CHEMINOLIN- 1IL) -PENYL] -PROPIONITRILE
CU20090081A7
(en)
Use of specific sgc stimulating and / or activating compounds; pharmaceutical formulation comprising said compounds; kit comprising the compounds, and use for the prevention and / or treatment of systematic sclerosis.
Pharmaceutical composition for the treatment of diabetes and related disorders, comprising an insulin sensitizer selected from pioglitazone and rosiglitazone, glimepiride and metmorphine; oral pharmaceutical formulation that comprises it; kit to treat type II diabetes; and use of said formulation to treat diabetes.