CU20080126A7 - PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH - Google Patents

PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

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Publication number
CU20080126A7
CU20080126A7 CU20080126A CU20080126A CU20080126A7 CU 20080126 A7 CU20080126 A7 CU 20080126A7 CU 20080126 A CU20080126 A CU 20080126A CU 20080126 A CU20080126 A CU 20080126A CU 20080126 A7 CU20080126 A7 CU 20080126A7
Authority
CU
Cuba
Prior art keywords
treatment
cellular growth
abnormal cellular
pirimidine derivatives
derivatives
Prior art date
Application number
CU20080126A
Other languages
Spanish (es)
Inventor
Jun Xiao
James Alfred Southers Jr
Gonghua Pan
Kendra Lousie Nelson
Arthur Douglas Brosius
Joel Thomas Arcari
Donn Gregory Wishka
Michael Joseph Luzzio
Samit Kumar Bhattacharya
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Priority to CU20080126A priority Critical patent/CU20080126A7/en
Publication of CU20080126A7 publication Critical patent/CU20080126A7/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un compuesto de fórmula I o una sal farmacéuticamente aceptable del mismo,en la que AR es un grupo de fórmula y R1, R2, R13 , A, K, M,L,L1, L2, W, X, Z, Z2, Y1, Y2, ,Z1,Z2, M,Q,W,X , mp,y q son como se definen en este documento. Dichos derivados de pirimidina son útiles en el tratamiento del crecimiento celular anormal, tal como cáncer, en mamíferos.. Esta invención se refiere a un procedimiento de uso de dichos compuestos en el trataminto del crecimiento celular anormal en mamíferos, especialmente seres humanos, y a composiciones farmacéuticas que contienen dichos compuestos.The present invention relates to a compound of formula I or a pharmaceutically acceptable salt thereof, wherein AR is a group of formula and R1, R2, R13, A, K, M, L, L1, L2, W, X , Z, Z2, Y1, Y2,, Z1, Z2, M, Q, W, X, mp, and q are as defined in this document. Said pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention relates to a method of using said compounds in the treatment of abnormal cell growth in mammals, especially humans, and to compositions. pharmaceuticals containing said compounds.

CU20080126A 2008-06-23 2008-06-23 PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH CU20080126A7 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CU20080126A CU20080126A7 (en) 2008-06-23 2008-06-23 PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20080126A CU20080126A7 (en) 2008-06-23 2008-06-23 PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

Publications (1)

Publication Number Publication Date
CU20080126A7 true CU20080126A7 (en) 2010-02-23

Family

ID=44280868

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20080126A CU20080126A7 (en) 2008-06-23 2008-06-23 PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

Country Status (1)

Country Link
CU (1) CU20080126A7 (en)

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