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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Un compuesto de la fórmula (I) ESPACIO PARA FÓRMULA (I) en la que: R3 representa un átom o de hidrógeno, y R1 y R2 forman juntos, con los átomos de carbono que los llevan, un ciclo de benceno, naftaleno o quinoleína, estando cada uno de estos ciclos eventualmente sustituido, o bien R1 representa un átomo de hidrógeno, y R2 y R3 forman juntos, con los átomos de carbono que los llevan, ciclo de benceno, naftaleno o quinoleína, estando cada uno de estos ciclos eventualmente sustituido, n representa 1ó 2, -X- representa un grupo elegido entre -(CH2)m-O-Ak-, -(CH2)m-NR4-Ak-, -(CO)-NR4-Ak- y -(CH2)m-NR4-(CO)-, m representa un número entero comprendido entre 1 y 6 ambos inclusive, Ak representa una cadena de alquileno eventualmente sustituida, y R4 representa un átomo de hidrógeno o un grupo alquilo, Ar representa un grupo arilo o heteroarilo, sus isómeros ópticos, así como sus sales de adición a un ácido farmacéuticamente aceptable. MedicamentosA compound of the formula (I) FORMULA SPACE (I) in which: R3 represents a hydrogen atom, and R1 and R2 together, with the carbon atoms that carry them, a benzene, naphthalene or quinolein cycle , each of these cycles being eventually substituted, or R1 represents a hydrogen atom, and R2 and R3 form together, with the carbon atoms that carry them, benzene, naphthalene or quinolein cycle, each of these cycles being eventually substituted, n represents 1 or 2, -X- represents a group chosen from - (CH2) mO-Ak-, - (CH2) m-NR4-Ak-, - (CO) -NR4-Ak- and - (CH2) m -NR4- (CO) -, m represents an integer between 1 and 6 inclusive, Ak represents an optionally substituted alkylene chain, and R4 represents a hydrogen atom or an alkyl group, Ar represents an aryl or heteroaryl group, their optical isomers, as well as their addition salts to a pharmaceutically acceptable acid. Medicines
CU20070216A2007-09-262007-09-26
DERIVATIVES OF INDANIL-PIPERAZINAS, ITS PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING IT
CU20070216A7
(en)
NEW DERIVATIVES OF 6-TRIAZOLOPIRIDACINA-SULFANIL BENZOTIAZOL AND BENCIMIDAZOL ITS PREPARATION PROCEDURE ITS APPLICATION AS MEDICINES PHARMACEUTICAL COMPOSITIONS AND NEW USE MAINLY AS MET INHIBITORS
NEW DERIVATIVES OF TRIAZOLO (4,3-A) PIRIDINA, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NEW USE IN PARTICULARLY AS MET INHIBITORS
NEW IMIDAZO DERIVATIVES (1,2-A) PIRIDINA, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NEW USE IN PARTICULARLY AS MET INHIBITORS
DERIVATIVES OF 1-BENCIL-CINOLIN-4- (1H) -ONA SUBSTITUTED, ITS PREPARATION, PHARMACEUTICAL COMPOSITIONS AND ITS USE IN THE TREATMENT OF PATHOLOGIES ASSOCIATED WITH RECEPTORS OF THE CANNABINOIDS CB2