CS974084A2 - Method of daunorubicine's and doxorubicine's nes morpholine derivatives production - Google Patents
Method of daunorubicine's and doxorubicine's nes morpholine derivatives productionInfo
- Publication number
- CS974084A2 CS974084A2 CS849740A CS974084A CS974084A2 CS 974084 A2 CS974084 A2 CS 974084A2 CS 849740 A CS849740 A CS 849740A CS 974084 A CS974084 A CS 974084A CS 974084 A2 CS974084 A2 CS 974084A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- daunorubicine
- doxorubicine
- nes
- morpholine derivatives
- derivatives production
- Prior art date
Links
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title 2
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 title 1
- 229960000975 daunorubicin Drugs 0.000 title 1
- 150000002780 morpholines Chemical class 0.000 title 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Anthracycline derivs. of formula (I) are new. R is COMe or CO.CH2OH; B is CN or OH, or (with the H atom attached to the same C) is oxo; R'' is H and R' is OH, or B plus R' are together an oxygen bridge. Pref. B is CN or completes oxo or O bridge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS849740A CS268514B2 (en) | 1983-07-19 | 1984-12-13 | Method of daunorubicine's and doxorubicine's nes morpholine derivatives production |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS835423A CS268512B2 (en) | 1983-07-19 | 1983-07-19 | Method of daunorubicine's and doxorubicine's new morpholine derivatives production |
| CS849740A CS268514B2 (en) | 1983-07-19 | 1984-12-13 | Method of daunorubicine's and doxorubicine's nes morpholine derivatives production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS974084A2 true CS974084A2 (en) | 1989-07-12 |
| CS268514B2 CS268514B2 (en) | 1990-03-14 |
Family
ID=5399112
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS835423A CS268512B2 (en) | 1983-07-19 | 1983-07-19 | Method of daunorubicine's and doxorubicine's new morpholine derivatives production |
| CS849740A CS268514B2 (en) | 1983-07-19 | 1984-12-13 | Method of daunorubicine's and doxorubicine's nes morpholine derivatives production |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS835423A CS268512B2 (en) | 1983-07-19 | 1983-07-19 | Method of daunorubicine's and doxorubicine's new morpholine derivatives production |
Country Status (1)
| Country | Link |
|---|---|
| CS (2) | CS268512B2 (en) |
-
1983
- 1983-07-19 CS CS835423A patent/CS268512B2/en unknown
-
1984
- 1984-12-13 CS CS849740A patent/CS268514B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS542383A2 (en) | 1989-07-12 |
| CS268514B2 (en) | 1990-03-14 |
| CS268512B2 (en) | 1990-03-14 |
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