CS67191A2 - Method of /-/-/2r, 3s/-2,3-epoxy-3-/4/ methoxyphenyl/- methyl propionate and its enantiomer preparation - Google Patents

Method of /-/-/2r, 3s/-2,3-epoxy-3-/4/ methoxyphenyl/- methyl propionate and its enantiomer preparation

Info

Publication number
CS67191A2
CS67191A2 CS91671A CS67191A CS67191A2 CS 67191 A2 CS67191 A2 CS 67191A2 CS 91671 A CS91671 A CS 91671A CS 67191 A CS67191 A CS 67191A CS 67191 A2 CS67191 A2 CS 67191A2
Authority
CS
Czechoslovakia
Prior art keywords
methoxyphenyl
epoxy
methyl propionate
enantiomer preparation
preparation
Prior art date
Application number
CS91671A
Other languages
Czech (cs)
Inventor
Lydia Zard
Arlette Tixidre
Guy Rossey
Alexander Wick
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9394762&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CS67191(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthelabo filed Critical Synthelabo
Publication of CS67191A2 publication Critical patent/CS67191A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Process for the preparation of methyl (-)-(2R,3S)-2,3-epoxy-3-(4-methoxyphenyl)propionate, characterised in that a solution of a mixture of enantiomers of trans methyl (+/-)-2,3-epoxy-3-(4-methoxyphenyl)propionate, rich in laevorotatory enantiomer, is prepared first of all and then a crystal seed of laevorotatory enantiomer is then added to the solution, which is allowed to crystallise, and the crystals formed are isolated.
CS91671A 1990-03-15 1991-03-14 Method of /-/-/2r, 3s/-2,3-epoxy-3-/4/ methoxyphenyl/- methyl propionate and its enantiomer preparation CS67191A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9003310A FR2659657B1 (en) 1990-03-15 1990-03-15 PROCESS FOR THE PREPARATION OF (-) (2R, 3S) -2,3-EPOXY-3- (4-METHOXYPHENYL) METHYL PROPIONATE.

Publications (1)

Publication Number Publication Date
CS67191A2 true CS67191A2 (en) 1991-11-12

Family

ID=9394762

Family Applications (1)

Application Number Title Priority Date Filing Date
CS91671A CS67191A2 (en) 1990-03-15 1991-03-14 Method of /-/-/2r, 3s/-2,3-epoxy-3-/4/ methoxyphenyl/- methyl propionate and its enantiomer preparation

Country Status (11)

Country Link
EP (1) EP0453330B2 (en)
JP (1) JP2854155B2 (en)
KR (1) KR910016671A (en)
AT (1) ATE85316T1 (en)
CS (1) CS67191A2 (en)
DE (1) DE69100026D1 (en)
FI (1) FI911264A7 (en)
FR (1) FR2659657B1 (en)
HU (1) HU206696B (en)
IE (1) IE910854A1 (en)
IL (1) IL97529A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW438787B (en) 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885375A (en) * 1988-05-18 1989-12-05 Marion Laboratories, Inc. Resolution of 3-(4-methoxyphenyl)glycidic acid with in situ conversion to alkyl esters

Also Published As

Publication number Publication date
IE910854A1 (en) 1991-09-25
DE69100026D1 (en) 1993-03-18
HU206696B (en) 1992-12-28
EP0453330B1 (en) 1993-02-03
FR2659657B1 (en) 1994-09-23
FR2659657A1 (en) 1991-09-20
KR910016671A (en) 1991-11-05
JPH04217969A (en) 1992-08-07
ATE85316T1 (en) 1993-02-15
HU910826D0 (en) 1991-09-30
HUT56838A (en) 1991-10-28
FI911264L (en) 1991-09-16
IL97529A0 (en) 1992-06-21
FI911264A7 (en) 1991-09-16
EP0453330A1 (en) 1991-10-23
FI911264A0 (en) 1991-03-14
IL97529A (en) 1995-12-31
JP2854155B2 (en) 1999-02-03
EP0453330B2 (en) 1997-12-03

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