CS262989A2 - Method of new substituted 2,4-diamino-5-cyanopyrimidines production - Google Patents
Method of new substituted 2,4-diamino-5-cyanopyrimidines productionInfo
- Publication number
- CS262989A2 CS262989A2 CS892629A CS262989A CS262989A2 CS 262989 A2 CS262989 A2 CS 262989A2 CS 892629 A CS892629 A CS 892629A CS 262989 A CS262989 A CS 262989A CS 262989 A2 CS262989 A2 CS 262989A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- alkyl
- cyanopyrimidines
- diamino
- production
- new substituted
- Prior art date
Links
- OYUQCQCQLDTRHQ-UHFFFAOYSA-N 2,4-diaminopyrimidine-5-carbonitrile Chemical class NC1=NC=C(C#N)C(N)=N1 OYUQCQCQLDTRHQ-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 101100134922 Gallus gallus COR5 gene Proteins 0.000 abstract 1
- 101001043818 Mus musculus Interleukin-31 receptor subunit alpha Proteins 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Derivs. of formula (I) and their salts are new. In (I) R1 = H, 1-6C alkyl, or 2-6C alkenyl or alkynyl; R2 = H, 1-10C alkyl or 3-6C cycloalkyl, or R1 and R2 are together (CH2)3, (CH2)4 or (CH2)5; R3 = H, COR5 or SO2R6; R4 = NH2, NHCOR5, NHSO2R6, -N=CR7-NR8R9 or -NH.CH=NR10; R5 = H, 1-12C alkyl, 3-6C cycloalkyl, 1-6C alkoxy, 1-3C perhaloalkyl or NR11R12; R6 = 1-6C alkyl; R7 = H, or 1-6C alkyl; R8 and R9 = H, or 1-6C alkyl, or together are (CH2)3, (CH2)4 or (CH2)5; R10 = SO2.R13 or -p(=x)(OR14)YR15; R11 and R12 are as R8 and R9; R13 = 1-10C alkyl (opt. substd. by 1-10 halo) or 3-6C cycloalkyl; R14 and R15 = 1-10C alkyl; X and Y = O or S. - Also new are the intermediates of formula (II), where R'1 and R'2 are as R1 and R2 but not together (CH2)3; n = 0-2. - Specifically claimed include (III); where A = H or EtCO; and Q = (a) or NEt2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS892629A CS272249B2 (en) | 1986-04-30 | 1989-04-28 | Method of new substituted 2,4-diamino-5-cyanopirimidines production |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH177286 | 1986-04-30 | ||
| CS873075A CS271471B2 (en) | 1986-04-30 | 1987-04-30 | Insecticide and acaricide and method of active substances production |
| CS892629A CS272249B2 (en) | 1986-04-30 | 1989-04-28 | Method of new substituted 2,4-diamino-5-cyanopirimidines production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS262989A2 true CS262989A2 (en) | 1990-02-12 |
| CS272249B2 CS272249B2 (en) | 1991-01-15 |
Family
ID=25688619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS892629A CS272249B2 (en) | 1986-04-30 | 1989-04-28 | Method of new substituted 2,4-diamino-5-cyanopirimidines production |
Country Status (1)
| Country | Link |
|---|---|
| CS (1) | CS272249B2 (en) |
-
1989
- 1989-04-28 CS CS892629A patent/CS272249B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS272249B2 (en) | 1991-01-15 |
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