CS217679B1 - Antifungal agent - Google Patents

Abstract

The purpose of the invention is to solve the problem of colorless fungicidal and anti-fungal protection of materials, especially wood and other cellulose materials. The stated purpose is achieved by the fact that the composition is formed by an aqueous solution of an inorganic compound containing antimony and fluorine. The invention can be used mainly in the protection of wood and other materials, as well as in museum and monument protection.

Description

SUMMARY OF THE INVENTION The present invention provides a fungicidal composition for protecting lignocellulosic and some other materials from the undesirable action of fungi and molds.

At present, a large number of inorganic and organic substances are known to have biocidal effects. Commonly mentioned are the following elements whose compounds are characterized by a certain fungitoxicity, decreasing in order:

Ag> Hg> Cu> Cd> Cr> Ni> Pb> Co> Zn> Fe ,.

So far, it has been argued that, of the elements classified by Mendeleyev's Periodic Law into Group V, only arsenic has some biocidal effect. Antimony belongs to the same group, but there are no data on its biocidal properties. The biocidal protection products used so far have many drawbacks. Usually, the protection is not sufficiently effective and durable. Some agents deteriorate the strength properties of the protected materials, while others cause unwanted discoloration and odor of the protected materials. In other cases, the active substance is poorly soluble and difficult to apply (impregnate) in protection, and some components of the preservatives are in turn too toxic to humans and animals and are also not ecologically satisfactory.

The aforementioned drawbacks are overcome by the fungicidal composition according to the invention, which consists of an aqueous solution of an inorganic compound containing antimony and fluorine.

Advantages of the fungicidal composition, the main component of which is ammonium pentafluoroantimonate, are high activity against fungi and fungi and low toxicity to humans and animals, as well as colorless treatment, which also does not cause undesirable odor of the protected materials. The active substance is water-soluble and penetrates and diffuses well through wood and other lignocellulosic materials. Wood protection is permanent and is not associated with a decrease in the mechanical properties of the materials to be protected if a pH of the preservative of 7 to 8 is ensured. By combining (NH ₄ ) ₂ SbF ₅ with some Cr ^vn and As compounds hazard of toxic effects on humans and animals. Another advantage of the composition of the invention is that it increases the fire resistance.

The main component of the fungicidal and antifungal agent are inorganic compounds containing antimony and fluorine in its molecule, e.g. in the form of ammonium pentafluoroantimonate (NH ₄ ) ₂ SbFs. Ammonium pentafluoroantimonate can be prepared by known methods from raw materials containing Sb ₂ O _{3 by} dissolving in an excess of hydrogen fluoride and adding ammonium carbonate, adjusting the pH of the solution to the neutral zone. Such a solution is itself suitable for use in the biocidal protection of materials or the effect of compounds containing Sb and F in the molecule ((NH ₄ ) ₂ SbF ₅ , SbF ₃ ) is combined with other compounds known for use in fungicidal protection. Preferred combinations are achieved using, in particular, the following water-soluble compounds: NaF, NH ₄ BF ₄ , Na ₃ CrFe, NaCr ₂ O ₇ , NaHA ₅ O ₄ . In some cases, it is preferable to use a water-soluble cellulose derivative (e.g. HEC) at a concentration of 0.1 to 1.0% as a fixing component.

Example 1

Fungicide test using so-called. poisoned agar pod.

The poisoned agar platform is obtained by mixing 13.5 ml of 3% malt agar and 1.5 ml of 0.1, 0.01, respectively. 0.001% aqueous (NH ₄ ) ₂ SbF ₅ solution. Grown wood-destroying fungi Corolius versicolore and Coniophora puteana were inoculated for the prepared agar alone and poisoned agar. An inoculum of 0.5 XX 0.5 mm was obtained with a scalpel and transferred with an inoculum needle onto agar stored in a Petri dish. Mycelium growth was performed at 25 + 2 ° C and relative humidity == 96% for 3 days. Mycelial growth was measured every day up to the edge of the Petri dish. The fungicidal effect was evaluated according to the relation:

CA = ^Xk ~ ^Xp . ioo Xk where CA - biocidal effect means a broader term and includes fungicidal, antifungal and insecticidal effect x _k - statically calculated average mycelium of the control x _p - Statistical mycelium average of the test sample

The effect was evaluated in a similar manner

SbF ₃ and ZnCl ₂ as with the known fungicide.

microorganism Coniophora puteana CA (%) Corolius versikolor CA (%) concentric tration 1.0% 0.1% 0.01% 0.001% (NH ₄ ) ₂ SbF ₅ 100 96 47 4 SbF ₃ 100 100 38 1 _ZnCl2 100 40 5 , (NH ₄ ) ₂ SbF ₅ 100 100 14 1 SbF ₃ 100 100 56 4 _ZnCl2 100 73 6

Example 2 impregnated with 0.1, 0.01, and 0.001% aqueous Pinius pine flow test pieces (NH ₄ ) ₂ SbF5. After air drying, take

Silvestris L. measuring 5 X 10 X 50 mm was placed in 5 ml of Kolle flasks in 100% malt agar which had been inoculated and infested with Coniophora puteana and Merulius lacrimans spongy cultures. (Non-impregnated beads were also inserted into Kolle flasks.) After 30 days of exposure, the beads were cleaned of fungal mycelium, allowed to dry freely and weight loss was observed:

CA =

UH _k - UH _S

ÚH _k

TJH _k - weight loss of control bodies ÚH _S - weight loss of impregnated bodies

microorganisms Coniophora putéana Merulius lacrimans concent. (%) 1.0 0.5 0.1 0.05 1.0 0.5 0.1 0.05 biological activity (%) 98.1 95.5 71.1 0.00 90.1 90.8 90.1 27.7 retention (kg / m ³ ) 4.29 2.13 0.43 0.21 3.58 1.78 0.35 0.17 weight loss (%) 0.31 0.69 4.47 24.18 0.91 0.48 0.95 6.67

Example 3

Test specimens impregnated with (NH ₄ ) ₂ SbF _{s solutions} were also used for the laboratory mold test. So-called. Geneva blend of fungal culture suspension and exposure for 15 days. Mold growth was checked visually (according to CSN 49 0605).

Concentration (NH ₄ ) ₂ SbF ₅ rating 1.0 resistant

0.5 partially resistant

0.1 resistant

The fungicidal agent according to the invention is primarily intended for the protection of wood in the area of historical monuments, museums, but also for protection in many other places of the national economy, e.g. anti-fungal plaster.

Claims (3)

3 • 100% 3% malt agar which has been pre-vaccinated and culminated by the fungal cultures of Co-niophora puteana and Merulius lacrimans. (They were also placed in the non-impregnated body of the Elbow flask.) After 30 days, satellite exposures were cleared from the fungal mycelia, allowed to dry, and weight loss was detected: CA = UHK - UHS UHK UHK - weight loss of control bodies impregnated tees Coniophora microorganisms Merulius lacrimans concentr. (%) 1.0 0.5 0.1 0.05 1.0 0.5 0.1 0.05 Biological Activity (%) 98.1 95.5 71.1 0.00 90.1 90.8 90.1 27.7 retention (kg / m2 3) 4.29 2.13 0.43 0.21 3.58 1.78 0.35 0.17 weight loss (%) 0.31 0.69 4, 47 24.18 0.91 0.48 0.95 6.67 Example 3 Test specimens impregnated with (NH4) 2SbFs solutions were also used for laboratory test molds. A so-called Geneva blend of sus-pellets of fungal cultures was used and exposure for 15 days. The growth of fungi was checked visually (according to CSN 49 0605). Concentration (NH4) 2SbF5 Rating1.0 Resistant 0.5 Partial Resistant 0.1 Unsupported The fungicidal agent, underlay is primarily intended for the protection of timber in the historical heritage, but also for the protection of many national economy sites, such as plaster antifungal. SUBJECT OF THE INVENTION A fungicidal composition comprising an aqueous solution of an inorganic compound containing amine and fluorine. 2. A fungicidal agent according to claim 1, characterized in that it consists of an aqueous solution of ammonium pentafluoronitrile, the concentration of which in the aqueous solution is from 0.001 to 5% by weight. 3. A fungicidal agent according to claim 1, wherein the aqueous antimony fluoride solution is a concentration of 0.01 to 10% by weight.