CS185623B2 - Process for preparing 7-beta-hydroxyphenylacetamido-3-heterocyclylthiomethylcephalosporines - Google Patents
Process for preparing 7-beta-hydroxyphenylacetamido-3-heterocyclylthiomethylcephalosporinesInfo
- Publication number
- CS185623B2 CS185623B2 CS7300004197A CS419773A CS185623B2 CS 185623 B2 CS185623 B2 CS 185623B2 CS 7300004197 A CS7300004197 A CS 7300004197A CS 419773 A CS419773 A CS 419773A CS 185623 B2 CS185623 B2 CS 185623B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- heterocyclylthiomethylcephalosporines
- hydroxyphenylacetamido
- beta
- preparing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US262903A US3867380A (en) | 1971-02-18 | 1972-06-14 | 3-Heterocyclic thiomethylcephalosporins |
Publications (1)
Publication Number | Publication Date |
---|---|
CS185623B2 true CS185623B2 (en) | 1978-10-31 |
Family
ID=22999565
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS7300004197A CS185623B2 (en) | 1972-06-14 | 1973-06-11 | Process for preparing 7-beta-hydroxyphenylacetamido-3-heterocyclylthiomethylcephalosporines |
Country Status (4)
Country | Link |
---|---|
BE (4) | BE796654A (en) |
CS (1) | CS185623B2 (en) |
SU (1) | SU550984A3 (en) |
ZA (3) | ZA731266B (en) |
-
1973
- 1973-02-22 ZA ZA731266A patent/ZA731266B/en unknown
- 1973-03-12 BE BE128695A patent/BE796654A/en not_active IP Right Cessation
- 1973-04-17 BE BE130109A patent/BE798331A/en unknown
- 1973-06-11 CS CS7300004197A patent/CS185623B2/en unknown
- 1973-06-13 SU SU1936456A patent/SU550984A3/en active
- 1973-06-13 BE BE132234A patent/BE800871A/en not_active IP Right Cessation
- 1973-06-13 BE BE132235A patent/BE800872A/en unknown
- 1973-06-14 ZA ZA734055A patent/ZA734055B/en unknown
- 1973-06-14 ZA ZA734054A patent/ZA734054B/en unknown
Also Published As
Publication number | Publication date |
---|---|
BE800872A (en) | 1973-12-13 |
ZA731266B (en) | 1973-11-28 |
BE796654A (en) | 1973-09-12 |
ZA734054B (en) | 1974-07-31 |
BE800871A (en) | 1973-12-13 |
BE798331A (en) | 1973-10-17 |
SU550984A3 (en) | 1977-03-15 |
ZA734055B (en) | 1974-07-31 |
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