CS178888B2 - Method for prouduction of new 4-phenyl-1,4-dihydropyridines - Google Patents

Method for prouduction of new 4-phenyl-1,4-dihydropyridines

Info

Publication number
CS178888B2
CS178888B2 CS7300004161A CS416173A CS178888B2 CS 178888 B2 CS178888 B2 CS 178888B2 CS 7300004161 A CS7300004161 A CS 7300004161A CS 416173 A CS416173 A CS 416173A CS 178888 B2 CS178888 B2 CS 178888B2
Authority
CS
Czechoslovakia
Prior art keywords
prouduction
dihydropyridines
phenyl
new
Prior art date
Application number
CS7300004161A
Other languages
Czech (cs)
English (en)
Inventor
Friedrich Bossert
Horst Beyer
Wulf Vater
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CS178888B2 publication Critical patent/CS178888B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CS7300004161A 1972-06-10 1973-06-08 Method for prouduction of new 4-phenyl-1,4-dihydropyridines CS178888B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2228363A DE2228363A1 (de) 1972-06-10 1972-06-10 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
CS178888B2 true CS178888B2 (en) 1977-10-31

Family

ID=5847399

Family Applications (5)

Application Number Title Priority Date Filing Date
CS7600001305A CS178900B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines
CS7600001303A CS178898B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines
CS7300004161A CS178888B2 (en) 1972-06-10 1973-06-08 Method for prouduction of new 4-phenyl-1,4-dihydropyridines
CS7600001302A CS178897B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines
CS7600001304A CS178899B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CS7600001305A CS178900B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines
CS7600001303A CS178898B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines

Family Applications After (2)

Application Number Title Priority Date Filing Date
CS7600001302A CS178897B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines
CS7600001304A CS178899B2 (en) 1972-06-10 1973-06-08 Method for production of new 4-phenyl-1,4-dihydropyridines

Country Status (19)

Country Link
US (1) US3923818A (xx)
JP (1) JPS4948680A (xx)
AT (2) AT328447B (xx)
AU (1) AU473996B2 (xx)
BE (1) BE800679A (xx)
CA (1) CA999592A (xx)
CH (7) CH591444A5 (xx)
CS (5) CS178900B2 (xx)
DD (1) DD109383A5 (xx)
DE (1) DE2228363A1 (xx)
ES (5) ES415749A1 (xx)
FR (1) FR2187347B1 (xx)
GB (1) GB1425059A (xx)
HU (1) HU166354B (xx)
IE (1) IE37773B1 (xx)
IL (1) IL42458A (xx)
NL (1) NL7308059A (xx)
SU (5) SU511856A3 (xx)
ZA (1) ZA733880B (xx)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3981882A (en) * 1972-08-31 1976-09-21 Bayer Aktiengesellschaft Process for preparing 4-aryl of hetero-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester
US3971796A (en) * 1973-07-12 1976-07-27 Bayer Aktiengesellschaft 1,4-Dihydropyridine esters
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
DE2847236A1 (de) * 1978-10-31 1980-05-14 Bayer Ag Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4252956A (en) * 1979-03-19 1981-02-24 Vigante Brigita A Derivatives of 1,4-dihydropyridine-3-carbothiol acids
GB2111978B (en) * 1981-10-19 1985-05-01 Maruko Pharmaceutical Co 1 4-dihydropyridine compounds
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
JPS60210640A (ja) * 1984-10-05 1985-10-23 Hitachi Chem Co Ltd 積層板の製造法
GB8503425D0 (en) * 1985-02-11 1985-03-13 Ici Plc Alkanolamine derivatives
GB8503427D0 (en) * 1985-02-11 1985-03-13 Ici Plc Basic compounds
GB8503428D0 (en) * 1985-02-11 1985-03-13 Ici Plc Nitrogen-containing compounds
GB8503429D0 (en) * 1985-02-11 1985-03-13 Ici Plc Chemical compounds
US4593033A (en) * 1985-04-24 1986-06-03 Merck & Co., Inc. Substituted indeno[2,1-c] pyridines useful as calcium channel blockers
US4605660A (en) * 1985-06-03 1986-08-12 Merck & Co., Inc. Indeno[2,1-c]pyridine compounds, and their use as calcium channel blockers
US4670443A (en) * 1985-07-02 1987-06-02 Merck & Co., Inc. Benzo(f)isoquinoline compounds useful as calcium entry blockers
DE3675747D1 (de) * 1985-08-21 1991-01-03 Glaxo Spa 1,4-dihydropyridinverbindungen und ihre herstellung und pharmazeutische formulierung.
IE59632B1 (en) * 1985-08-21 1994-03-09 Glaxo Spa Heterocyclic derivatives
US4735956A (en) * 1985-09-13 1988-04-05 Merck & Co., Inc. Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers
US4721708A (en) * 1985-11-26 1988-01-26 Merck & Co., Inc. Cyclized N-substituted-tetrahydropyridine compounds and cardiovascular use
US4788203A (en) * 1985-11-26 1988-11-29 Merck & Co., Inc. Cyclized N-substituted-tetrahydropyridine compounds, useful in the treatment of cardiovascular disorders
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
EP0330470A3 (en) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. 1,4-dihydropyridine derivatives useful against tumour cells
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
FR2672890A1 (fr) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.
EP1108710A4 (en) * 1998-07-23 2001-11-21 Chen Ing Jun GUAIACOXYPROPANOLAMINE WITH ALPHA / BETA ADRENERGIC INHIBIT ACTIVITY
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20030153773A1 (en) * 2002-02-14 2003-08-14 Wayne Gregory S. Process for the production of dihydropyridines
WO2005016885A2 (en) * 2003-08-14 2005-02-24 Artesian Therapeutics, Inc. COMPOUNDS WITH COMBINED CALCIUM CHANNEL BLOCKER AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITIES FOR TREATMENT OF HEART DISEASE
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
ZA7152B (en) * 1970-01-24 1971-10-27 Bayer Ag New pharmaceutically active 1,4-dihydropyridines

Also Published As

Publication number Publication date
ATA177075A (de) 1975-08-15
IL42458A0 (en) 1973-08-29
CH589629A5 (xx) 1977-07-15
CS178898B2 (en) 1977-10-31
AT329561B (de) 1976-05-25
ZA733880B (en) 1974-05-29
SU510997A3 (ru) 1976-04-15
JPS4948680A (xx) 1974-05-11
ATA507473A (de) 1975-06-15
CA999592A (en) 1976-11-09
ES415749A1 (es) 1976-06-16
CH591444A5 (xx) 1977-09-15
CH588462A5 (xx) 1977-06-15
HU166354B (xx) 1975-03-28
CH591443A5 (xx) 1977-09-15
IE37773B1 (en) 1977-10-12
SU512708A3 (ru) 1976-04-30
ES440619A1 (es) 1977-03-01
DE2228363A1 (de) 1974-01-03
ES440621A1 (es) 1977-03-01
AU5672573A (en) 1974-12-12
GB1425059A (en) 1976-02-18
CS178897B2 (en) 1977-10-31
SU511856A3 (ru) 1976-04-25
AT328447B (de) 1976-03-25
CS178900B2 (en) 1977-10-31
DD109383A5 (xx) 1974-11-05
US3923818A (en) 1975-12-02
CH589058A5 (xx) 1977-06-30
CH593260A5 (xx) 1977-11-30
FR2187347B1 (xx) 1977-09-09
AU473996B2 (en) 1976-07-08
FR2187347A1 (xx) 1974-01-18
SU509221A3 (ru) 1976-03-30
BE800679A (fr) 1973-12-10
IL42458A (en) 1977-07-31
NL7308059A (xx) 1973-12-12
CH589628A5 (xx) 1977-07-15
SU507234A3 (ru) 1976-03-15
ES440622A1 (es) 1977-03-01
ES440620A1 (es) 1977-03-01
CS178899B2 (en) 1977-10-31
IE37773L (en) 1973-12-10

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