CS178888B2 - Method for prouduction of new 4-phenyl-1,4-dihydropyridines - Google Patents
Method for prouduction of new 4-phenyl-1,4-dihydropyridinesInfo
- Publication number
- CS178888B2 CS178888B2 CS7300004161A CS416173A CS178888B2 CS 178888 B2 CS178888 B2 CS 178888B2 CS 7300004161 A CS7300004161 A CS 7300004161A CS 416173 A CS416173 A CS 416173A CS 178888 B2 CS178888 B2 CS 178888B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- prouduction
- dihydropyridines
- phenyl
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2228363A DE2228363A1 (de) | 1972-06-10 | 1972-06-10 | 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
CS178888B2 true CS178888B2 (en) | 1977-10-31 |
Family
ID=5847399
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS7600001304A CS178899B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
CS7600001302A CS178897B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
CS7600001303A CS178898B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
CS7600001305A CS178900B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
CS7300004161A CS178888B2 (en) | 1972-06-10 | 1973-06-08 | Method for prouduction of new 4-phenyl-1,4-dihydropyridines |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS7600001304A CS178899B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
CS7600001302A CS178897B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
CS7600001303A CS178898B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
CS7600001305A CS178900B2 (en) | 1972-06-10 | 1973-06-08 | Method for production of new 4-phenyl-1,4-dihydropyridines |
Country Status (19)
Country | Link |
---|---|
US (1) | US3923818A (ru) |
JP (1) | JPS4948680A (ru) |
AT (2) | AT329561B (ru) |
AU (1) | AU473996B2 (ru) |
BE (1) | BE800679A (ru) |
CA (1) | CA999592A (ru) |
CH (7) | CH589058A5 (ru) |
CS (5) | CS178899B2 (ru) |
DD (1) | DD109383A5 (ru) |
DE (1) | DE2228363A1 (ru) |
ES (5) | ES415749A1 (ru) |
FR (1) | FR2187347B1 (ru) |
GB (1) | GB1425059A (ru) |
HU (1) | HU166354B (ru) |
IE (1) | IE37773B1 (ru) |
IL (1) | IL42458A (ru) |
NL (1) | NL7308059A (ru) |
SU (5) | SU511856A3 (ru) |
ZA (1) | ZA733880B (ru) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3981882A (en) * | 1972-08-31 | 1976-09-21 | Bayer Aktiengesellschaft | Process for preparing 4-aryl of hetero-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester |
US3971796A (en) * | 1973-07-12 | 1976-07-27 | Bayer Aktiengesellschaft | 1,4-Dihydropyridine esters |
US4466972A (en) * | 1977-06-20 | 1984-08-21 | Sandoz Ltd. | Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them |
DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
US4252956A (en) * | 1979-03-19 | 1981-02-24 | Vigante Brigita A | Derivatives of 1,4-dihydropyridine-3-carbothiol acids |
GB2111978B (en) * | 1981-10-19 | 1985-05-01 | Maruko Pharmaceutical Co | 1 4-dihydropyridine compounds |
DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
IE57810B1 (en) * | 1984-03-27 | 1993-04-21 | Delagrange Lab | 1,4-dihydropyridine derivatives,their preparation and their use |
NZ212895A (en) * | 1984-08-22 | 1988-07-28 | Glaxo Spa | 1,4-dihydropyridine derivatives and pharmaceutical compositions |
JPS60210640A (ja) * | 1984-10-05 | 1985-10-23 | Hitachi Chem Co Ltd | 積層板の製造法 |
GB8503427D0 (en) * | 1985-02-11 | 1985-03-13 | Ici Plc | Basic compounds |
GB8503429D0 (en) * | 1985-02-11 | 1985-03-13 | Ici Plc | Chemical compounds |
GB8503425D0 (en) * | 1985-02-11 | 1985-03-13 | Ici Plc | Alkanolamine derivatives |
GB8503428D0 (en) * | 1985-02-11 | 1985-03-13 | Ici Plc | Nitrogen-containing compounds |
US4593033A (en) * | 1985-04-24 | 1986-06-03 | Merck & Co., Inc. | Substituted indeno[2,1-c] pyridines useful as calcium channel blockers |
US4605660A (en) * | 1985-06-03 | 1986-08-12 | Merck & Co., Inc. | Indeno[2,1-c]pyridine compounds, and their use as calcium channel blockers |
US4670443A (en) * | 1985-07-02 | 1987-06-02 | Merck & Co., Inc. | Benzo(f)isoquinoline compounds useful as calcium entry blockers |
GB2181127B (en) * | 1985-08-21 | 1989-08-02 | Glaxo Spa | 4-phenyl-dihydropyridine carboxylic acid derivatives |
EP0226271B1 (en) * | 1985-08-21 | 1990-11-22 | GLAXO S.p.A. | 1,4-dihydropyridine compounds and their preparation and pharmaceutical formulation |
US4735956A (en) * | 1985-09-13 | 1988-04-05 | Merck & Co., Inc. | Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers |
US4721708A (en) * | 1985-11-26 | 1988-01-26 | Merck & Co., Inc. | Cyclized N-substituted-tetrahydropyridine compounds and cardiovascular use |
US4788203A (en) * | 1985-11-26 | 1988-11-29 | Merck & Co., Inc. | Cyclized N-substituted-tetrahydropyridine compounds, useful in the treatment of cardiovascular disorders |
IT1204462B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
IT1204460B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
US5216172A (en) * | 1988-02-24 | 1993-06-01 | Ajinomoto Co., Inc. | 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells |
EP0330470A3 (en) * | 1988-02-24 | 1992-01-02 | Ajinomoto Co., Inc. | 1,4-dihydropyridine derivatives useful against tumour cells |
FR2672890A1 (fr) * | 1991-02-20 | 1992-08-21 | Inst Investigacion Desarrol | Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres. |
AU8430098A (en) * | 1998-07-23 | 2000-02-14 | Ing-Jun Chen | Guaiacoxypropanolamines with alpha/beta-adrenergic blocking activity |
ATE445838T1 (de) | 2001-07-25 | 2009-10-15 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
US20030153773A1 (en) * | 2002-02-14 | 2003-08-14 | Wayne Gregory S. | Process for the production of dihydropyridines |
WO2005016885A2 (en) * | 2003-08-14 | 2005-02-24 | Artesian Therapeutics, Inc. | COMPOUNDS WITH COMBINED CALCIUM CHANNEL BLOCKER AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITIES FOR TREATMENT OF HEART DISEASE |
EP2671508B1 (en) | 2005-04-28 | 2020-09-16 | Proteus Digital Health, Inc. | Pharma-informatics system |
CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
HUE059078T2 (hu) | 2009-02-20 | 2022-10-28 | Enhanx Biopharm Inc | Glutation-alapú hatóanyagszállító rendszer |
JP2012526144A (ja) | 2009-05-06 | 2012-10-25 | ラボラトリー スキン ケア インコーポレイテッド | 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法 |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1923990C3 (de) * | 1969-05-10 | 1978-11-23 | Bayer Ag | Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern |
ZA7152B (en) * | 1970-01-24 | 1971-10-27 | Bayer Ag | New pharmaceutically active 1,4-dihydropyridines |
-
1972
- 1972-06-10 DE DE2228363A patent/DE2228363A1/de active Pending
-
1973
- 1973-05-31 SU SU1926944A patent/SU511856A3/ru active
- 1973-06-04 US US366578A patent/US3923818A/en not_active Expired - Lifetime
- 1973-06-07 CA CA173,419A patent/CA999592A/en not_active Expired
- 1973-06-07 JP JP48063442A patent/JPS4948680A/ja active Pending
- 1973-06-07 IL IL7342458A patent/IL42458A/en unknown
- 1973-06-07 HU HUBA2938A patent/HU166354B/hu unknown
- 1973-06-08 CS CS7600001304A patent/CS178899B2/cs unknown
- 1973-06-08 CS CS7600001302A patent/CS178897B2/cs unknown
- 1973-06-08 DD DD171438A patent/DD109383A5/xx unknown
- 1973-06-08 CH CH250477A patent/CH589058A5/xx not_active IP Right Cessation
- 1973-06-08 GB GB2746373A patent/GB1425059A/en not_active Expired
- 1973-06-08 CH CH250377A patent/CH591444A5/xx not_active IP Right Cessation
- 1973-06-08 AU AU56725/73A patent/AU473996B2/en not_active Expired
- 1973-06-08 AT AT177075*7A patent/AT329561B/de not_active IP Right Cessation
- 1973-06-08 CS CS7600001303A patent/CS178898B2/cs unknown
- 1973-06-08 CH CH725976A patent/CH589629A5/xx not_active IP Right Cessation
- 1973-06-08 CH CH836973A patent/CH591443A5/xx not_active IP Right Cessation
- 1973-06-08 BE BE132064A patent/BE800679A/xx unknown
- 1973-06-08 CH CH725876A patent/CH589628A5/xx not_active IP Right Cessation
- 1973-06-08 CS CS7600001305A patent/CS178900B2/cs unknown
- 1973-06-08 CH CH725776A patent/CH593260A5/xx not_active IP Right Cessation
- 1973-06-08 FR FR7320978A patent/FR2187347B1/fr not_active Expired
- 1973-06-08 ZA ZA733880A patent/ZA733880B/xx unknown
- 1973-06-08 IE IE932/73A patent/IE37773B1/xx unknown
- 1973-06-08 CS CS7300004161A patent/CS178888B2/cs unknown
- 1973-06-08 NL NL7308059A patent/NL7308059A/xx not_active Application Discontinuation
- 1973-06-08 AT AT507473A patent/AT328447B/de not_active IP Right Cessation
- 1973-06-08 CH CH725676A patent/CH588462A5/xx not_active IP Right Cessation
- 1973-06-09 ES ES415749A patent/ES415749A1/es not_active Expired
-
1974
- 1974-06-27 SU SU2038435A patent/SU507234A3/ru active
- 1974-06-27 SU SU2038430A patent/SU510997A3/ru active
- 1974-07-23 SU SU2050563A patent/SU509221A3/ru active
- 1974-07-23 SU SU2050564A patent/SU512708A3/ru active
-
1975
- 1975-09-01 ES ES440620A patent/ES440620A1/es not_active Expired
- 1975-09-01 ES ES440621A patent/ES440621A1/es not_active Expired
- 1975-09-01 ES ES440619A patent/ES440619A1/es not_active Expired
- 1975-09-01 ES ES440622A patent/ES440622A1/es not_active Expired
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