CR8697A - HIRTINA CHIRAL DERIVATIVES FOR THE PREPARATION OF EPOTILONES AND PROCESSES TO PREPARE THEM - Google Patents

HIRTINA CHIRAL DERIVATIVES FOR THE PREPARATION OF EPOTILONES AND PROCESSES TO PREPARE THEM

Info

Publication number
CR8697A
CR8697A CR8697A CR8697A CR8697A CR 8697 A CR8697 A CR 8697A CR 8697 A CR8697 A CR 8697A CR 8697 A CR8697 A CR 8697A CR 8697 A CR8697 A CR 8697A
Authority
CR
Costa Rica
Prior art keywords
hirtina
epotilones
prepare
processes
preparation
Prior art date
Application number
CR8697A
Other languages
Spanish (es)
Inventor
Johannes Platzek
Orlin Petrov
Marc Willuhn
Klaus-Dieter Graske
Werner Skuballa
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04090157A external-priority patent/EP1589011A1/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of CR8697A publication Critical patent/CR8697A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/36—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)

Abstract

La invencion se relaciona con un proceso para la produccion de intermediarios clave, utiles en la sintesis de epotilonas o derivados de epotilona, con determinados copuestos usados para la produccion de estos intermediarios clave, y con un proceso para la produccion de dichos compuestos.The invention relates to a process for the production of key intermediaries, useful in the synthesis of epothilones or derivatives of epothilone, with certain compounds used for the production of these key intermediates, and with a process for the production of said compounds.

CR8697A 2004-04-22 2006-10-19 HIRTINA CHIRAL DERIVATIVES FOR THE PREPARATION OF EPOTILONES AND PROCESSES TO PREPARE THEM CR8697A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04090157A EP1589011A1 (en) 2004-04-22 2004-04-22 Novel chiral heptyne derivates for the preparation of epothilones and processes for their preparation
US56584904P 2004-04-28 2004-04-28

Publications (1)

Publication Number Publication Date
CR8697A true CR8697A (en) 2008-09-01

Family

ID=35456170

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8697A CR8697A (en) 2004-04-22 2006-10-19 HIRTINA CHIRAL DERIVATIVES FOR THE PREPARATION OF EPOTILONES AND PROCESSES TO PREPARE THEM

Country Status (6)

Country Link
KR (1) KR20070027536A (en)
CR (1) CR8697A (en)
EC (1) ECSP066998A (en)
HR (1) HRP20070566T3 (en)
IL (1) IL178113A0 (en)
NO (1) NO20065364L (en)

Also Published As

Publication number Publication date
IL178113A0 (en) 2006-12-31
HRP20070566T3 (en) 2008-01-31
KR20070027536A (en) 2007-03-09
ECSP066998A (en) 2006-12-29
NO20065364L (en) 2007-01-17

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)