CR8045A - DERIVATIVES OF ALCANOS AZA ESPIRO AS INHIBITORS OF METALOPROTEASES - Google Patents
DERIVATIVES OF ALCANOS AZA ESPIRO AS INHIBITORS OF METALOPROTEASESInfo
- Publication number
- CR8045A CR8045A CR8045A CR8045A CR8045A CR 8045 A CR8045 A CR 8045A CR 8045 A CR8045 A CR 8045A CR 8045 A CR8045 A CR 8045A CR 8045 A CR8045 A CR 8045A
- Authority
- CR
- Costa Rica
- Prior art keywords
- alcanos
- metaloproteases
- espiro
- aza
- inhibitors
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Esta invencion proporciona un compuesto de formula I o formula II: o enantiomero, diaestereoisomero, prodroga, solvato, metabolito o sal farmaceuticamente aceptable del mismo, donde las variables constituyentes se proporcionan en este docuemnto. Los compuestosd de Formula I y II son moduladores de metaloproteasas y son utiles en el tratamiento de enfermedades asociadas con la actividad metaloproteasa como artritis, cancer, trastornos cardiovasculares, trastornos de la piel ,inflamacion y condiciones alergicas.This invention provides a compound of formula I or formula II: or enantiomer, diastereoisomer, prodrug, solvate, metabolite or pharmaceutically acceptable salt thereof, where the constituent variables are provided in this document. The compounds of Formula I and II are metalloprotease modulators and are useful in the treatment of diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46615903P | 2003-04-24 | 2003-04-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR8045A true CR8045A (en) | 2006-05-29 |
Family
ID=37390761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR8045A CR8045A (en) | 2003-04-24 | 2005-10-14 | DERIVATIVES OF ALCANOS AZA ESPIRO AS INHIBITORS OF METALOPROTEASES |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN1863532A (en) |
| CR (1) | CR8045A (en) |
| UA (1) | UA88444C2 (en) |
| ZA (1) | ZA200509496B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11851475B2 (en) | 2018-01-03 | 2023-12-26 | Xi'an Jiaotong-Liverpool University | Membrane-type metalloprotease inhibitory protein and pharmaceutical and pharmaceutical composition containing same, and respective uses thereof |
| CN109394786A (en) * | 2018-10-26 | 2019-03-01 | 西交利物浦大学 | A kind of antitumor medicine composition |
-
2004
- 2004-04-23 CN CN 200480017350 patent/CN1863532A/en active Pending
- 2004-04-23 UA UAA200511110A patent/UA88444C2/en unknown
-
2005
- 2005-10-14 CR CR8045A patent/CR8045A/en not_active Application Discontinuation
- 2005-11-23 ZA ZA200509496A patent/ZA200509496B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1863532A (en) | 2006-11-15 |
| UA88444C2 (en) | 2009-10-26 |
| ZA200509496B (en) | 2006-10-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1117221T1 (en) | AZA SPIRAL PRODUCER AZA AS METAL PROTECTION SUSPENSIONS | |
| PA8680701A1 (en) | OXINDOL DERIVATIVES | |
| CR7785A (en) | TIAZOL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | |
| DOP2006000061A (en) | PIRIMIDINE DERIVATIVES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | |
| CR8644A (en) | IMIDAZOL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | |
| SV2005001973A (en) | USEFUL KINOLINES IN THE TREATMENT OF CARDIOVASCULAR DISEASES REF. WYTH0090-504 (AM101500) | |
| UY30500A1 (en) | AZABENCIMIDAZOLILO COMPOUNDS | |
| ECSP066972A (en) | MUTUAL PROMOTES OF GLUCOSAMINE AND GLUCOSAMINE / ANTI-INFLAMMATORY, COMPOSITIONS, AND METHODS | |
| UY28691A1 (en) | DERIVATIVES OF DIFENILAZETIDONA | |
| ECSP066717A (en) | SUBSTITUTED QUINOLINE COMPOUNDS | |
| UY28473A1 (en) | NEW COMPOUNDS | |
| ECSP088099A (en) | NEW DERIVATIVES OF 2-AZETIDINONE FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | |
| SV2006002187A (en) | USEFUL INDAZOLS FOR TREATMENTS OF CARDIOVASCULAR DISEASES REF.WYTH0089-504 (AM101590) | |
| CR8497A (en) | DERIVATIVES OF AZEPINOINDOL AS PHARMACEUTICAL AGENTS | |
| EA200700909A1 (en) | AZAINDOLKARBOXAMIDES | |
| UY28144A1 (en) | THERAPEUTIC AGENTS | |
| UY29796A1 (en) | NEW COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL, PSYCHIATRIC OR PAIN DISORDERS | |
| CR10304A (en) | TETRAHYDROPIRIDOTIENOPIRIMIDINE COMPOUNDS AND PROCEDURES FOR THE SAME USE | |
| ATE412414T1 (en) | 3,11B-CIS-DIHYDROTETRABENAZINE FOR THE TREATMENT OF PROLIFERATIVE DISEASES OR INFLAMMATION | |
| UY30835A1 (en) | 8-ALQUINILXANTINAS AND DERIVATIVES | |
| ATE356621T1 (en) | (S)-2-N-PROPYLAMINO-5-HYDROXYTETRALINE AS A D3 AGONIST THERAPEUTIC | |
| UY28484A1 (en) | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | |
| HN2003000379A (en) | USEFUL ANILINOPIRAZOL DERIVATIVES IN THE TREATMENT OF DIABETES | |
| GB0416508D0 (en) | Therapeutic agents | |
| CR8045A (en) | DERIVATIVES OF ALCANOS AZA ESPIRO AS INHIBITORS OF METALOPROTEASES |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal | ||
| FC | Refusal |