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Application filed by Pfizer Prod IncfiledCriticalPfizer Prod Inc
Publication of CR7749ApublicationCriticalpatent/CR7749A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Se describen nuevos compuestos de imidazol, incluyendo sus derivados, intermedios para su preparacion, composiciones farmaceuticas que los contienen y su uso medicinal. Los componentes de la presente invencion son inhibidores potentes de la ruta de senalizacion del factor de crecimiento transformante ("TGF"). Son de utilidad en el tratamiento de diversos estados de enfermedad relacionados con TGF icluyendo por ejemplo, cancer, y enfermedades fibroticas.New imidazole compounds are described, including their derivatives, intermediates for their preparation, pharmaceutical compositions containing them and their medicinal use. The components of the present invention are potent inhibitors of the transformative growth factor signaling pathway ("TGF"). They are useful in the treatment of various disease states related to TGF including, for example, cancer, and fibrotic diseases.
CR7749A2002-09-182005-03-16
NEW IMIDAZOL COMPOUNDS AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF)
CR7749A
(en)