CR7622A - SEQUENCES OF THE CONTROL OF THE GENE OF HUMAN CORINA - Google Patents
SEQUENCES OF THE CONTROL OF THE GENE OF HUMAN CORINAInfo
- Publication number
- CR7622A CR7622A CR7622A CR7622A CR7622A CR 7622 A CR7622 A CR 7622A CR 7622 A CR7622 A CR 7622A CR 7622 A CR7622 A CR 7622A CR 7622 A CR7622 A CR 7622A
- Authority
- CR
- Costa Rica
- Prior art keywords
- corina
- gene
- control
- sequences
- human
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 230000014509 gene expression Effects 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
S e relaciona con el aislamiento , la clonacion, y la identificacion de las regiones de control de la expresion del gen de corina en mamiferos, incluyendo el promotor y otros elementos reguladores, y el uso de esta region de control de la expresion especifica del corazoon para indentificar nuevos agentes que modulan la expresion de gen de corina y para tratar enfermedades cardiacas.It is related to the isolation, cloning, and identification of the control regions of the expression of the corina gene in mammals, including the promoter and other regulatory elements, and the use of this control region of the specific expression of the heart to identify new agents that modulate the gene expression of corina and to treat heart disease.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38410802P | 2002-05-31 | 2002-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR7622A true CR7622A (en) | 2006-05-29 |
Family
ID=29711979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR7622A CR7622A (en) | 2002-05-31 | 2004-12-15 | SEQUENCES OF THE CONTROL OF THE GENE OF HUMAN CORINA |
Country Status (18)
Country | Link |
---|---|
US (1) | US20030223976A1 (en) |
EP (1) | EP1546172A4 (en) |
JP (1) | JP2005531302A (en) |
KR (1) | KR20050009724A (en) |
CN (1) | CN1671729A (en) |
AU (1) | AU2003245342A1 (en) |
BR (1) | BR0311603A (en) |
CA (1) | CA2487024A1 (en) |
CR (1) | CR7622A (en) |
EC (1) | ECSP045518A (en) |
IL (1) | IL165244A0 (en) |
MX (1) | MXPA04011944A (en) |
NO (1) | NO20045722L (en) |
PL (1) | PL374125A1 (en) |
RS (1) | RS104404A (en) |
RU (1) | RU2004139055A (en) |
WO (1) | WO2003102135A2 (en) |
ZA (1) | ZA200410400B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050026255A1 (en) * | 2002-06-25 | 2005-02-03 | Morser John Michael | Corin, a serine protease |
CN101061217A (en) * | 2004-02-27 | 2007-10-24 | 通用医疗公司 | Methods and compositions for hair growth |
JP5680274B2 (en) | 2005-12-01 | 2015-03-04 | チバ ホールディング インコーポレーテッドCiba Holding Inc. | Oxime ester photoinitiator |
US20110306069A1 (en) | 2009-02-19 | 2011-12-15 | Qingyu Wu | Corin As A Marker For Heart Failure |
CN105734070A (en) * | 2016-04-11 | 2016-07-06 | 苏州大学 | Corin gene variant and application thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5917123A (en) * | 1997-03-14 | 1999-06-29 | University Of Pittsburgh | Transgenic mice containing a nucleic acid encoding tumor necrosis factor-α under the control of a cardiac specific regulatory region |
ATE397074T1 (en) * | 1998-06-05 | 2008-06-15 | Bayer Schering Pharma Ag | CORIN, A SERINE PROTEASE |
CA2296792A1 (en) * | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
EP1252300B1 (en) * | 2000-02-03 | 2011-01-19 | Dendreon Corporation | Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon |
AU2001243142A1 (en) * | 2000-02-03 | 2001-08-14 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
JP2001245671A (en) * | 2000-03-07 | 2001-09-11 | Chiba Prefecture | New gene cloned in human neuroblastoma and fragment thereof |
-
2003
- 2003-05-28 RS YU104404A patent/RS104404A/en unknown
- 2003-05-28 KR KR10-2004-7019340A patent/KR20050009724A/en not_active Application Discontinuation
- 2003-05-28 AU AU2003245342A patent/AU2003245342A1/en not_active Abandoned
- 2003-05-28 CN CNA03818169XA patent/CN1671729A/en active Pending
- 2003-05-28 JP JP2004510377A patent/JP2005531302A/en active Pending
- 2003-05-28 CA CA002487024A patent/CA2487024A1/en not_active Abandoned
- 2003-05-28 BR BR0311603-4A patent/BR0311603A/en not_active IP Right Cessation
- 2003-05-28 IL IL16524403A patent/IL165244A0/en unknown
- 2003-05-28 RU RU2004139055/13A patent/RU2004139055A/en not_active Application Discontinuation
- 2003-05-28 WO PCT/US2003/016741 patent/WO2003102135A2/en active Application Filing
- 2003-05-28 EP EP03738981A patent/EP1546172A4/en not_active Withdrawn
- 2003-05-28 MX MXPA04011944A patent/MXPA04011944A/en not_active Application Discontinuation
- 2003-05-28 US US10/447,476 patent/US20030223976A1/en not_active Abandoned
- 2003-05-28 PL PL03374125A patent/PL374125A1/en not_active Application Discontinuation
-
2004
- 2004-12-15 CR CR7622A patent/CR7622A/en not_active Application Discontinuation
- 2004-12-23 ZA ZA200410400A patent/ZA200410400B/en unknown
- 2004-12-28 EC EC2004005518A patent/ECSP045518A/en unknown
- 2004-12-30 NO NO20045722A patent/NO20045722L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2004139055A (en) | 2005-08-20 |
IL165244A0 (en) | 2005-12-18 |
NO20045722L (en) | 2004-12-30 |
AU2003245342A1 (en) | 2003-12-19 |
CA2487024A1 (en) | 2003-12-11 |
CN1671729A (en) | 2005-09-21 |
WO2003102135A3 (en) | 2004-11-04 |
RS104404A (en) | 2006-12-15 |
US20030223976A1 (en) | 2003-12-04 |
ZA200410400B (en) | 2006-06-28 |
EP1546172A4 (en) | 2005-11-30 |
WO2003102135A2 (en) | 2003-12-11 |
BR0311603A (en) | 2005-06-07 |
EP1546172A2 (en) | 2005-06-29 |
MXPA04011944A (en) | 2005-03-31 |
PL374125A1 (en) | 2005-10-03 |
KR20050009724A (en) | 2005-01-25 |
JP2005531302A (en) | 2005-10-20 |
ECSP045518A (en) | 2005-03-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal (granting procedure) |