CR20190211A - Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator - Google Patents

Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator

Info

Publication number
CR20190211A
CR20190211A CR20190211A CR20190211A CR20190211A CR 20190211 A CR20190211 A CR 20190211A CR 20190211 A CR20190211 A CR 20190211A CR 20190211 A CR20190211 A CR 20190211A CR 20190211 A CR20190211 A CR 20190211A
Authority
CR
Costa Rica
Prior art keywords
modulator
methods
making
pharmaceutical compositions
cystic fibrosis
Prior art date
Application number
CR20190211A
Other languages
Spanish (es)
Inventor
Jason Mccartney
Corey Anderson
Thomas Cleveland
Pramod Virupax Joshi
Jinglan Zhou
Minson Baek
Bryan A Frieman
Brett Bradley Busch
David Andrew Siesel
Ali Keshavarz-Shokri
Rachel Mcauley-Aoki
Goor Fredrick Van
Andreas P Termin
Prasuna Paraselli
Peter Grootenhuis
Robert M Hughes
Timothy Alcacio
Ruah Sara Sabina Hadida
Beili Zhang
Paul John Krenitsky
Johnny Uy
Haripada; Khatuya
Vito; Melillo
Mark Thomas Miller
Fabrice Jean Denis Pierre
Alexander Russell Abela
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Priority claimed from PCT/US2017/054611 external-priority patent/WO2018064632A1/en
Publication of CR20190211A publication Critical patent/CR20190211A/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of Formula (I), pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.Compuestos de Fórmula I: sales farmacéuticamente aceptables de este, derivados deuterados de cualquiera de los precedentes y metabolitos de cualquiera de los precedentes se describen. También se describen composiciones farmacéuticas que los comprenden, métodos para tratar la fibrosis quística usándolos y métodos para producirlos.
CR20190211A 2016-09-30 2017-09-29 Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator CR20190211A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662402838P 2016-09-30 2016-09-30
US201662410353P 2016-10-19 2016-10-19
US201662415409P 2016-10-31 2016-10-31
PCT/US2017/054611 WO2018064632A1 (en) 2016-09-30 2017-09-29 Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator

Publications (1)

Publication Number Publication Date
CR20190211A true CR20190211A (en) 2019-07-11

Family

ID=67910532

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20190211A CR20190211A (en) 2016-09-30 2017-09-29 Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator

Country Status (1)

Country Link
CR (1) CR20190211A (en)

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