CO6592037A2 - Combination of an aine and an amino acid - Google Patents
Combination of an aine and an amino acidInfo
- Publication number
- CO6592037A2 CO6592037A2 CO12212627A CO12212627A CO6592037A2 CO 6592037 A2 CO6592037 A2 CO 6592037A2 CO 12212627 A CO12212627 A CO 12212627A CO 12212627 A CO12212627 A CO 12212627A CO 6592037 A2 CO6592037 A2 CO 6592037A2
- Authority
- CO
- Colombia
- Prior art keywords
- combination
- aine
- amino acid
- composition
- pharmaceutically acceptable
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010065390 Inflammatory pain Diseases 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- 229930064664 L-arginine Natural products 0.000 abstract 1
- 235000014852 L-arginine Nutrition 0.000 abstract 1
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- HEFNNWSXXWATRW-JTQLQIEISA-N dexibuprofen Chemical class CC(C)CC1=CC=C([C@H](C)C(O)=O)C=C1 HEFNNWSXXWATRW-JTQLQIEISA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a una composición farmacéutica oral que comprende la combinación de una sal de ibuprofeno o S(+)-ibuprofeno con L-arginina y/o sus sales farmacéuticamente aceptables, adicionalmente, vehículos y/o excipientes farmacéuticamente aceptables; el proceso de fabricación de la composición y el uso de dicha composición con actividad terapéutica sinérgica, indicada para el tratamiento de dolor inflamatorio de moderado a severo, fiebre e inflamación.The present invention relates to an oral pharmaceutical composition comprising the combination of an ibuprofen or S (+) - ibuprofen salt with L-arginine and / or its pharmaceutically acceptable salts, additionally, pharmaceutically acceptable carriers and / or excipients; the manufacturing process of the composition and the use of said composition with synergistic therapeutic activity, indicated for the treatment of moderate to severe inflammatory pain, fever and inflammation.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2010004974A MX2010004974A (en) | 2010-05-04 | 2010-05-04 | Nonsteroideal anti-inflammatory and aminoacid composition. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6592037A2 true CO6592037A2 (en) | 2013-01-02 |
Family
ID=44903664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO12212627A CO6592037A2 (en) | 2010-05-04 | 2012-11-23 | Combination of an aine and an amino acid |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9186342B2 (en) |
| AR (1) | AR081007A1 (en) |
| BR (1) | BR112012028300A2 (en) |
| CA (1) | CA2798420C (en) |
| CL (1) | CL2012003065A1 (en) |
| CO (1) | CO6592037A2 (en) |
| CR (1) | CR20120554A (en) |
| DO (1) | DOP2012000280A (en) |
| EC (1) | ECSP13012765A (en) |
| ES (1) | ES2424417B1 (en) |
| GT (1) | GT201200295A (en) |
| MX (1) | MX2010004974A (en) |
| PE (2) | PE20130316A1 (en) |
| WO (1) | WO2011138653A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019010692A (en) * | 2019-09-06 | 2022-07-06 | Alparis Sa De Cv | Curcumin compounds and basic amino acids. |
| US11969400B2 (en) * | 2021-03-23 | 2024-04-30 | Kumara V. Nibhanipudi | Ibuprofen for symptomatic treatment of diarrheas in HIV patients |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1209667B (en) | 1985-11-12 | 1989-08-30 | Zambon Spa | EFFEVERSCENT COMPOSITION ANALGESIC ADAPTITY. |
| IT1197038B (en) * | 1986-08-01 | 1988-11-25 | Zambon Spa | PHARMACEUTICAL COMPOSITION WITH ANALGESIC ACTIVITY |
| IT1264856B1 (en) * | 1993-06-21 | 1996-10-17 | Zambon Spa | PHARMACEUTICAL COMPOSITION WITH ANALGESIC ACTIVITY |
| DK1439830T3 (en) | 2001-11-02 | 2006-02-13 | Cumberland Pharmaceuticals Inc | Pharmaceutical preparation with 2- (4-isobutylphenyl) propionic acid |
| US6727286B2 (en) * | 2001-11-02 | 2004-04-27 | Cumberland Pharmaceuticals Inc. | Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid |
| CN101889997B (en) | 2010-07-26 | 2012-10-03 | 石家庄中硕药业集团有限公司 | Ibuprofen-containing medicinal composition for injection |
-
2010
- 2010-05-04 MX MX2010004974A patent/MX2010004974A/en active IP Right Grant
-
2011
- 2011-04-28 CA CA2798420A patent/CA2798420C/en not_active Expired - Fee Related
- 2011-04-28 WO PCT/IB2011/000916 patent/WO2011138653A1/en active Application Filing
- 2011-04-28 PE PE2012002113A patent/PE20130316A1/en active IP Right Grant
- 2011-04-28 US US13/696,022 patent/US9186342B2/en active Active
- 2011-04-28 ES ES201290078A patent/ES2424417B1/en not_active Expired - Fee Related
- 2011-04-28 BR BR112012028300A patent/BR112012028300A2/en not_active Application Discontinuation
- 2011-05-04 AR ARP110101530A patent/AR081007A1/en unknown
-
2012
- 2012-10-30 CR CR20120554A patent/CR20120554A/en unknown
- 2012-10-31 CL CL2012003065A patent/CL2012003065A1/en unknown
- 2012-10-31 DO DO2012000280A patent/DOP2012000280A/en unknown
- 2012-10-31 GT GT201200295A patent/GT201200295A/en unknown
- 2012-11-23 CO CO12212627A patent/CO6592037A2/en not_active Application Discontinuation
-
2013
- 2013-07-15 EC ECSP13012765 patent/ECSP13012765A/en unknown
-
2016
- 2016-02-02 PE PE2016000218A patent/PE20170136A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CL2012003065A1 (en) | 2013-01-11 |
| WO2011138653A1 (en) | 2011-11-10 |
| RU2012151921A (en) | 2014-06-10 |
| BR112012028300A2 (en) | 2016-11-01 |
| GT201200295A (en) | 2014-01-03 |
| PE20170136A1 (en) | 2017-03-05 |
| CA2798420A1 (en) | 2011-11-10 |
| ES2424417A2 (en) | 2013-10-01 |
| ES2424417B1 (en) | 2014-11-26 |
| CA2798420C (en) | 2018-06-05 |
| CR20120554A (en) | 2013-02-01 |
| ES2424417R1 (en) | 2013-12-20 |
| MX2010004974A (en) | 2011-11-23 |
| AR081007A1 (en) | 2012-05-30 |
| DOP2012000280A (en) | 2012-12-31 |
| US9186342B2 (en) | 2015-11-17 |
| ECSP13012765A (en) | 2013-09-30 |
| US20130109754A1 (en) | 2013-05-02 |
| PE20130316A1 (en) | 2013-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |