CO5280142A1 - VIRAL PARTICLES WITH EXOGENOUS EPITHOPES. . - Google Patents

VIRAL PARTICLES WITH EXOGENOUS EPITHOPES. .

Info

Publication number
CO5280142A1
CO5280142A1 CO00078905A CO00078905A CO5280142A1 CO 5280142 A1 CO5280142 A1 CO 5280142A1 CO 00078905 A CO00078905 A CO 00078905A CO 00078905 A CO00078905 A CO 00078905A CO 5280142 A1 CO5280142 A1 CO 5280142A1
Authority
CO
Colombia
Prior art keywords
exogenous
epithopes
viral particles
capsid
mfi
Prior art date
Application number
CO00078905A
Other languages
Spanish (es)
Inventor
Hellendoorn Koen
Jones Tim
Original Assignee
Dow Chwmical Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chwmical Company filed Critical Dow Chwmical Company
Publication of CO5280142A1 publication Critical patent/CO5280142A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203—Virus mediated transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
    • C12N2760/18722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un compuesto que comprende una partícula viral quimérica que tiene un cápside, en donde el cápside tiene un lado interior y un lado exterior, el cápside comprendiendo cuando menos un péptido exógeno en el lado interior del cápside.<EMI FILE="00078905_1" ID="1" IMF=JPEG >A compound comprising a chimeric viral particle having a capsid, wherein the capsid has an inner side and an outer side, the capsid comprising at least one exogenous peptide on the inner side of the capsid. <EMI FILE = "00078905_1" ID = "1" MFI = JPEG>

CO00078905A 1999-10-14 2000-10-17 VIRAL PARTICLES WITH EXOGENOUS EPITHOPES. . CO5280142A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9924352.9A GB9924352D0 (en) 1999-10-14 1999-10-14 Methods,compositions and applications relating to the generation of novel plant viral particles

Publications (1)

Publication Number Publication Date
CO5280142A1 true CO5280142A1 (en) 2003-05-30

Family

ID=10862753

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00078905A CO5280142A1 (en) 1999-10-14 2000-10-17 VIRAL PARTICLES WITH EXOGENOUS EPITHOPES. .

Country Status (16)

Country Link
EP (1) EP1235910A1 (en)
JP (1) JP2003534771A (en)
KR (1) KR100880477B1 (en)
CN (2) CN101591647A (en)
AR (1) AR026066A1 (en)
AU (1) AU785020B2 (en)
BR (1) BR0014861A (en)
CA (1) CA2387626A1 (en)
CO (1) CO5280142A1 (en)
CZ (1) CZ20021303A3 (en)
GB (1) GB9924352D0 (en)
IL (1) IL149077A0 (en)
MX (1) MXPA02003789A (en)
PL (1) PL354933A1 (en)
WO (1) WO2001027282A1 (en)
ZA (1) ZA200202815B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000855A2 (en) * 2001-06-21 2003-01-03 Uab Research Foundation Chimeric capsid proteins and uses thereof
US8101189B2 (en) 2002-07-05 2012-01-24 Folia Biotech Inc. Vaccines and immunopotentiating compositions and methods for making and using them
MXPA05000287A (en) 2002-07-05 2005-09-08 Leclerc Denis Adjuvant viral particle.
CA2583113C (en) 2004-10-05 2015-11-10 Diversa Corporation Compositions comprising an antigen and a promiscuous t-cell epitope
US20070041999A1 (en) * 2005-06-01 2007-02-22 Lada Rasochova Production of multivalent virus like particles
WO2007011904A2 (en) * 2005-07-19 2007-01-25 Dow Global Technologies Inc. Recombinant flu vaccines
AU2008279584A1 (en) * 2007-04-27 2009-01-29 Dow Global Technologies Inc. Improved production and in vivo assembly of soluble recombinant icosahedral virus-like particles
WO2013003353A2 (en) * 2011-06-30 2013-01-03 Stc.Unm Plasmids and methods for peptide display and affinity-selection on virus-like particles of rna bacteriophages

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108386D0 (en) * 1991-04-19 1991-06-05 Agricultural Genetics Co Modified plant viruses as vectors
GB9712282D0 (en) * 1997-06-12 1997-08-13 Innes John Centre Innov Ltd Epitope presentation system

Also Published As

Publication number Publication date
IL149077A0 (en) 2002-11-10
KR100880477B1 (en) 2009-01-28
WO2001027282A1 (en) 2001-04-19
KR20020040868A (en) 2002-05-30
CN1471580A (en) 2004-01-28
EP1235910A1 (en) 2002-09-04
PL354933A1 (en) 2004-03-22
JP2003534771A (en) 2003-11-25
AR026066A1 (en) 2002-12-26
MXPA02003789A (en) 2002-09-30
CA2387626A1 (en) 2001-04-19
WO2001027282A8 (en) 2001-08-16
AU1085201A (en) 2001-04-23
AU785020B2 (en) 2006-08-24
GB9924352D0 (en) 1999-12-15
CN101591647A (en) 2009-12-02
CZ20021303A3 (en) 2002-10-16
ZA200202815B (en) 2003-08-27
BR0014861A (en) 2002-07-16

Similar Documents

Publication Publication Date Title
USD451046S1 (en) Ring
RU2001129709A (en) Macrocyclic peptides with activity against hepatitis C virus
USD490309S1 (en) Smoothwall container
USD480956S1 (en) Portion of container
ZA200107862B (en) Macrocyclic peptides active against the hepatitis c virus.
CO4960659A1 (en) VACCINE INCLUDING AN ANTIGEN FOR HEPATITIS B VIRUSES AND AN ANTIGEN FOR HERPES SIMPLEX VIRUS
USD485069S1 (en) Latch for a protective case
ES2167374T3 (en) CONNECTOR TO LOCK AN INTERNAL CANNULA INSIDE AN EXTERNAL CANNULA.
CO5160309A1 (en) ABSORBENT ITEMS THAT HAVE HUMIDITY INDICATOR GRAPHICS INCORPORATING A LEARNING REGION
BR9903056B1 (en) airtight non-metallic composite container.
CO5280142A1 (en) VIRAL PARTICLES WITH EXOGENOUS EPITHOPES. .
Lafforgue A proof of property (RD) for cocompact lattices of SL (3, R) and SL (3, C)
EP1003202A3 (en) Discharge lamp
AU7923900A (en) Retaining net
EP1305438A4 (en) Improved virus like particles based on small envelope protein from hepatitis b (hbsag-s)
DE60222788D1 (en) RADAR COUPLING WITH LOW RADAR CROSS SECTION
USD517775S1 (en) Belt
DE69738512D1 (en) EPSTEIN-BARR VIRUS TYPE B CTL EPITOPES
USD473009S1 (en) Reflector for a flashlight
USD434325S (en) Fragrance bottle
USD472704S1 (en) Transportation container
USD473510S1 (en) Equipment carrying case
USD436078S1 (en) Lamp socket
USD460502S1 (en) Paintball tube
USD513656S1 (en) Shorts

Legal Events

Date Code Title Description
FA Application withdrawn