CO5241278A1 - VACCINE - Google Patents

VACCINE

Info

Publication number
CO5241278A1
CO5241278A1 CO00027740A CO00027740A CO5241278A1 CO 5241278 A1 CO5241278 A1 CO 5241278A1 CO 00027740 A CO00027740 A CO 00027740A CO 00027740 A CO00027740 A CO 00027740A CO 5241278 A1 CO5241278 A1 CO 5241278A1
Authority
CO
Colombia
Prior art keywords
serotype
mpl
compositions
aluminum
polysaccharide conjugates
Prior art date
Application number
CO00027740A
Other languages
Spanish (es)
Inventor
Carine Capiau
Marguerite Deschamps
Michel Desmons Pierre
Laferriere Craig Antony Joseph
Jan Poolman
Jean Paul Prieels
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9909077.1A external-priority patent/GB9909077D0/en
Priority claimed from GBGB9909466.6A external-priority patent/GB9909466D0/en
Priority claimed from GBGB9916677.9A external-priority patent/GB9916677D0/en
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of CO5241278A1 publication Critical patent/CO5241278A1/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Una composición antigénica que comprende uno o más conjugados polisacáridos capsulares de Streptococcus pneumoniae coadyuvados con 3D-MPL y sustancialmentedesprovistos de coadyuvantes basados en aluminio, en la que al menos uno de los conjugados polisacáridos de Streptococcus pneumoniae es significativamente màs inmunogénico en composiciones que comprenden 3D-MPL, en comparación con composiciones que comprenden 3D-MPL junto con un coadyuvante basado en aluminio. Una composición antigénica sustancialmente desprovista de coadyuvantes basados en aluminio y que comprende el coadyuvante 3D-MPL y dos o más conjugados polisacáridos pneumocóccicos elegidos del grupo consistente en: serotipo 4, serotipo 6B, serotipo 18C, serotipo 19F, y serotipo 23F.An antigenic composition comprising one or more capsular polysaccharide conjugates of Streptococcus pneumoniae coadjuvated with 3D-MPL and substantially devoid of aluminum-based adjuvants, in which at least one of the Streptococcus pneumoniae polysaccharide conjugates is significantly more immunogenic in compositions which comprise 3D immunogenic in compositions that comprise 3D MPL, compared to compositions comprising 3D-MPL together with an aluminum-based adjuvant. An antigenic composition substantially devoid of aluminum-based adjuvants and comprising the 3D-MPL adjuvant and two or more pneumococcal polysaccharide conjugates chosen from the group consisting of: serotype 4, serotype 6B, serotype 18C, serotype 19F, and serotype 23F.

CO00027740A 1999-04-20 2000-04-14 VACCINE CO5241278A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9909077.1A GB9909077D0 (en) 1999-04-20 1999-04-20 Novel compositions
GBGB9909466.6A GB9909466D0 (en) 1999-04-23 1999-04-23 Vaccines
GBGB9916677.9A GB9916677D0 (en) 1999-07-15 1999-07-15 Vaccine

Publications (1)

Publication Number Publication Date
CO5241278A1 true CO5241278A1 (en) 2003-01-31

Family

ID=40956460

Family Applications (3)

Application Number Title Priority Date Filing Date
CO00027743A CO5210947A1 (en) 1999-04-20 2000-04-14 IMMUNOGENIC COMPOSITIONS THAT INCLUDE A STREPTOCCUS PNEUMONIAE POLISACARIDE ANTIGEN
CO00027739A CO5241277A1 (en) 1999-04-20 2000-04-14 VACCINE
CO00027740A CO5241278A1 (en) 1999-04-20 2000-04-14 VACCINE

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CO00027743A CO5210947A1 (en) 1999-04-20 2000-04-14 IMMUNOGENIC COMPOSITIONS THAT INCLUDE A STREPTOCCUS PNEUMONIAE POLISACARIDE ANTIGEN
CO00027739A CO5241277A1 (en) 1999-04-20 2000-04-14 VACCINE

Country Status (1)

Country Link
CO (3) CO5210947A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection

Also Published As

Publication number Publication date
CO5210947A1 (en) 2002-10-30
CO5241277A1 (en) 2003-01-31

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Legal Events

Date Code Title Description
FC Application refused