CO5160246A1 - METHOD FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EPISODES ASSOCIATED WITH CORONARY INTERVENTIONS - Google Patents

METHOD FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EPISODES ASSOCIATED WITH CORONARY INTERVENTIONS

Info

Publication number
CO5160246A1
CO5160246A1 CO00006605A CO00006605A CO5160246A1 CO 5160246 A1 CO5160246 A1 CO 5160246A1 CO 00006605 A CO00006605 A CO 00006605A CO 00006605 A CO00006605 A CO 00006605A CO 5160246 A1 CO5160246 A1 CO 5160246A1
Authority
CO
Colombia
Prior art keywords
prevention
reduction
coronary
approximately
coronary interventions
Prior art date
Application number
CO00006605A
Other languages
Spanish (es)
Inventor
Jeffrey R Granett
H Shusterman Neil
Prichard David C U
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of CO5160246A1 publication Critical patent/CO5160246A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Un método para la prevención o la reducción de episodios cardiovasculares asociados con intervenciones coronarias en mamíferos, particularmente en personas, que comprende administrar al sujeto ácido N-(3´,4´-dimetoxicinamoil)antranílico (N-5´) o una sal del mismo aceptable farmacéuticamente en una dosis diaria de aproximadamente 300 mg a aproximadamente 1.100 mg en asociación con la intervención coronaria.1El uso de ácido N-(3´,4´-dimetoxicinamoil)antranílico (N-5´), o una sal del mismo aceptable farmacéuticamente, en la confección de un medicamento para ser usado en la prevención o la reducción de episodios cardiovasculares asociados con intervenciones coronarias en un mamífero, en particular en una persona, cuando se administra en asociación con una intervención coronaria en una dosis diaria de aproximadamente 300 mg a aproximadamente 1.100 mg.2Una composición farmacéutica para ser usada en la prevención o la reducción de episodios cardiovasculares asociados con intervenciones coronarias en un mamífero, en particular en una persona, cuando se administra en asociación con una interverción coronaria en una dosis diaria de aproximadamente 300 mg a aproximadamente 1.100 mg, que comprende ácido N-(3´,4´-dimetoxicinamoil)antranílico (N-5´) o una sal del mismo aceptable farmacéuticamente.A method for the prevention or reduction of cardiovascular events associated with coronary interventions in mammals, particularly in people, which comprises administering to the subject N- (3´, 4´-dimethoxycinnamoyl) anthranilic acid (N-5´) or a salt of the same pharmaceutically acceptable at a daily dose of about 300 mg to about 1,100 mg in association with coronary intervention.1 The use of N- (3´, 4´-dimethoxycinnamoyl) anthranilic acid (N-5´), or a salt thereof pharmaceutically acceptable, in the preparation of a medicament for use in the prevention or reduction of cardiovascular events associated with coronary interventions in a mammal, in particular in a person, when administered in association with a coronary intervention in a daily dose of approximately 300 mg to approximately 1,100 mg. 2 A pharmaceutical composition for use in the prevention or reduction of associated cardiovascular events. os with coronary interventions in a mammal, particularly in a person, when administered in association with a coronary intervention at a daily dose of approximately 300 mg to approximately 1,100 mg, comprising N- (3´, 4´-dimethoxycinnamoil) anthranilic (N-5 ') or a pharmaceutically acceptable salt thereof.

CO00006605A 1999-02-03 2000-02-03 METHOD FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EPISODES ASSOCIATED WITH CORONARY INTERVENTIONS CO5160246A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11846399P 1999-02-03 1999-02-03

Publications (1)

Publication Number Publication Date
CO5160246A1 true CO5160246A1 (en) 2002-05-30

Family

ID=22378760

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00006605A CO5160246A1 (en) 1999-02-03 2000-02-03 METHOD FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EPISODES ASSOCIATED WITH CORONARY INTERVENTIONS

Country Status (17)

Country Link
EP (1) EP1180027A4 (en)
JP (1) JP2002536326A (en)
KR (1) KR20010101933A (en)
CN (1) CN1338930A (en)
AR (1) AR022475A1 (en)
AU (1) AU2978500A (en)
BR (1) BR0007901A (en)
CA (1) CA2361578A1 (en)
CO (1) CO5160246A1 (en)
HU (1) HUP0200148A3 (en)
IL (1) IL144719A0 (en)
MX (1) MXPA01007833A (en)
NO (1) NO20013789L (en)
PL (1) PL349926A1 (en)
TR (1) TR200102262T2 (en)
WO (1) WO2000045810A1 (en)
ZA (1) ZA200106297B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097650B2 (en) * 2005-07-27 2012-01-17 The Trustees Of Columbia University In The City Of New York Method of treating a condition associated with phosphorylation of TASK-1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2617407B2 (en) * 1992-09-14 1997-06-04 キッセイ薬品工業株式会社 Preventive and therapeutic agent for intimal cell hyperproliferative disease
WO1997009301A1 (en) * 1995-09-07 1997-03-13 Kissei Pharmaceutical Co., Ltd. 2-acylaminobenzamide derivatives and preventive and remedy for diseases caused by the supermultiplication of vascular intimal cells
US6019104A (en) * 1996-12-30 2000-02-01 Kissei Pharmaceutical Co., Ltd. Method for the treatment or prevention of restenosis associated with coronary intervention

Also Published As

Publication number Publication date
CN1338930A (en) 2002-03-06
ZA200106297B (en) 2002-07-31
BR0007901A (en) 2001-10-30
NO20013789D0 (en) 2001-08-02
EP1180027A1 (en) 2002-02-20
KR20010101933A (en) 2001-11-15
MXPA01007833A (en) 2002-06-21
TR200102262T2 (en) 2002-02-21
WO2000045810A1 (en) 2000-08-10
HUP0200148A2 (en) 2002-05-29
AR022475A1 (en) 2002-09-04
CA2361578A1 (en) 2000-08-10
AU2978500A (en) 2000-08-25
PL349926A1 (en) 2002-10-21
HUP0200148A3 (en) 2003-06-30
JP2002536326A (en) 2002-10-29
EP1180027A4 (en) 2004-11-17
IL144719A0 (en) 2002-06-30
NO20013789L (en) 2001-09-28

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