CO4890853A1 - STABLE PROTEIN AND NUCLEIC ACID FORMULATIONS USING NON-AQUEOUS, ANHYDRID, APROTIC, HYDROPHOBIC, NON-POLAR VEHICLES WITH LOW REACTIVITY - Google Patents

STABLE PROTEIN AND NUCLEIC ACID FORMULATIONS USING NON-AQUEOUS, ANHYDRID, APROTIC, HYDROPHOBIC, NON-POLAR VEHICLES WITH LOW REACTIVITY

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Publication number
CO4890853A1
CO4890853A1 CO97060474A CO97060474A CO4890853A1 CO 4890853 A1 CO4890853 A1 CO 4890853A1 CO 97060474 A CO97060474 A CO 97060474A CO 97060474 A CO97060474 A CO 97060474A CO 4890853 A1 CO4890853 A1 CO 4890853A1
Authority
CO
Colombia
Prior art keywords
nucleic acid
aprotic
hydrophobic
low reactivity
aqueous
Prior art date
Application number
CO97060474A
Other languages
Spanish (es)
Inventor
Victoria Marie Knepp
Steven J Prestrelski
Jessica G Smith
T F Huang Manley
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CO4890853A1 publication Critical patent/CO4890853A1/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Una composición de proteína no acuosa estable que comprende: a) un polvo proteináceo en donde la hidratación de proteína en dicho polvo es menor del 10%; y b) al menos un vehículo de reactividad baja anhidroso, aprótico, hidrofóbico. 1Una composición de ácido nucleico estable que comprende: a) un polvo que contiene ácido nucleico en donde la hidratación del ácido nucleico en dicho polvo es menor al 10; y b) al menos un vehículo anhidroso, no polar, aprótico, hidrofóbico, de baja reactividad.A stable non-aqueous protein composition comprising: a) a proteinaceous powder wherein the protein hydration in said powder is less than 10%; and b) at least one anhydrous, aprotic, hydrophobic low reactivity vehicle. 1 A stable nucleic acid composition comprising: a) a nucleic acid containing powder wherein the hydration of the nucleic acid in said powder is less than 10; and b) at least one low reactivity, non-polar, aprotic, hydrophobic, anhydrous vehicle.

CO97060474A 1996-10-16 1997-10-15 STABLE PROTEIN AND NUCLEIC ACID FORMULATIONS USING NON-AQUEOUS, ANHYDRID, APROTIC, HYDROPHOBIC, NON-POLAR VEHICLES WITH LOW REACTIVITY CO4890853A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2816796P 1996-10-16 1996-10-16

Publications (1)

Publication Number Publication Date
CO4890853A1 true CO4890853A1 (en) 2000-02-28

Family

ID=27658092

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97060474A CO4890853A1 (en) 1996-10-16 1997-10-15 STABLE PROTEIN AND NUCLEIC ACID FORMULATIONS USING NON-AQUEOUS, ANHYDRID, APROTIC, HYDROPHOBIC, NON-POLAR VEHICLES WITH LOW REACTIVITY

Country Status (4)

Country Link
CO (1) CO4890853A1 (en)
MY (1) MY125597A (en)
TW (1) TW534815B (en)
ZA (1) ZA977959B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI683666B (en) 2013-03-15 2020-02-01 美商百歐維拉提夫治療公司 Factor ix polypeptide formulations

Also Published As

Publication number Publication date
TW534815B (en) 2003-06-01
ZA977959B (en) 1998-03-23
MY125597A (en) 2006-08-30

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