CO4780024A1 -
NEW HYDROXAMIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES RELATED TO THE DEGRADATION OF THE CONNECTIVE TISSUE
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NEW HYDROXAMIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES RELATED TO THE DEGRADATION OF THE CONNECTIVE TISSUE
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Priority to CO97012510ApriorityCriticalpatent/CO4780024A1/en
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Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
Reivindicación número 1.-Un compuesto de fórmula Io sus sales farmacéuticamente aceptables, en dondeX esa) -(CH2 )-,b) -NR5 -, oc) -C(=O)-;Y esa) -(CH2 )-, ob) -NR5 -;con la condición de que cuando X es -NR5 -, entonces Y es -(CH2 )-;R1 esa) H,b) C1 -20 alquilo,c) -(CH2 )i - Arilo,d) -(CH2 )i - -O-R5 ,d) - (CH2 )i -Het,e) -C(=O) NH (CH2 )j -Arilo,f) -C(=O) NH (CH2 )k NR6 R7 ,g) -C(=O) NH (CH2 )K -S-(CH2 )j NR6 R7 ,h) -C(=O) NH (CH2 )k -NHSO2 -Arilo,i) C(=O) NH (CH2 )k -NHSO2 NR6 R7 , oClaim number 1.-A compound of formula I or its pharmaceutically acceptable salts, where X esa) - (CH2) -, b) -NR5 -, oc) -C (= O) -; Y esa) - (CH2) -, or b) -NR5 -; with the proviso that when X is -NR5 -, then Y is - (CH2) -; R1 that) H, b) C1 -20 alkyl, c) - (CH2) i - Aryl, d ) - (CH2) i - -O-R5, d) - (CH2) i -Het, e) -C (= O) NH (CH2) j -Aril, f) -C (= O) NH (CH2) k NR6 R7, g) -C (= O) NH (CH2) K -S- (CH2) j NR6 R7, h) -C (= O) NH (CH2) k -NHSO2 -Aryl, i) C (= O) NH (CH2) k -NHSO2 NR6 R7, or
CO97012510A1997-03-071997-03-07
NEW HYDROXAMIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES RELATED TO THE DEGRADATION OF THE CONNECTIVE TISSUE
CO4780024A1
(en)
ANALOGS OF 20-EPI-16-ENO OF VITAMIN D3, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, PROCEDURE FOR THE PREPARATION OF SUCH COMPOUNDS AND USE OF SUCH COMPOUNDS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS
SUBSTITUTED BENZENOSULPHONYL-UREAS-THIOUREAS, PROCEDURE FOR THEIR PREPARATION, ITS USE AS A MEDICINAL PRODUCT OR DIAGNOSTIC AGENT, AS WELL AS A MEDICINAL PRODUCT CONTAINING THEM.
O-ALCANOYL DERIVATIVES OF 3-AMINO-2-HYDROXYPROPANSULFONIC ACID WITH ANTICONVULSIVE ACTIVITY AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM FOR THERAPEUTIC TREATMENT OF EPILEPSY.
THERAPEUTIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES CONNECTED WITH GLUTATION DEFICIENCY, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT