CO4750652A1 - DERIVATIVES OF AZACICLOALCANOS, ITS PREPARATION AND ITS APPLICATIONS IN THERAPEUTICS - Google Patents
DERIVATIVES OF AZACICLOALCANOS, ITS PREPARATION AND ITS APPLICATIONS IN THERAPEUTICSInfo
- Publication number
- CO4750652A1 CO4750652A1 CO96021765A CO96021765A CO4750652A1 CO 4750652 A1 CO4750652 A1 CO 4750652A1 CO 96021765 A CO96021765 A CO 96021765A CO 96021765 A CO96021765 A CO 96021765A CO 4750652 A1 CO4750652 A1 CO 4750652A1
- Authority
- CO
- Colombia
- Prior art keywords
- group
- carbon atoms
- linear
- branched alkyl
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Derivados de azacicloalcanos caracterizados porque tiene lasiguiente fórmula (I):en la cual:* R1 y R2 , que pueden ser idénticos o diferentes entre si, representan, cada uno de ellos, un átomo de hidrógeno, un grupo alquilo lineal, ramificado o cíclico que comprende de 1 a 6 átomos de carbono, o un grupo fenilo eventualmente sustituido por un grupo alquilo lineal o ramificado que comprende de 1 a 6 átomos de carbono, por uno o dos átomos de halógeno o por un grupo COOR6 , siendo R6 un átomo de hidrógeno o un grupo alquilo lineal o ramificado que comprende de 1 a 6 átomos de carbono; ó R1 y R2 forman conjuntamente un grupo oxo; * R3 representa un átomo de hidrógeno o un grupo alquilo lineal o ramificado que comprende de 1 a 4 átomos de carbono, o bien R3 forma un grupo metileno; * R4 representa un grupo aromático elegido entre un grupo fenilo, naftilo o piridinilo, eventualmente sustituido por un grupo alquilo lineal o ramificado que comprende de 1 a 6 átomos de carbono, por uno o dos átomos de halógeno, por un grupo nitro, o por un grupo COOR6 siendo R6 como definido en lo que precede; o, cuando R3 forma un grupo metileno, entonces R4 representa un grupo fenileno uno de cuyos átomos de carbono está vinculado a Y y otro de cuyos átomos de carbono, adyacente al recién mencionado, está vinculado a dicho grupo metileno;* R5 es sea un grupo OR7 siendo R7 un átomo de hidrógeno o un grupo bencilo, sea un grupo N4 -metil- piperazinilo, sea todavía un grupo NHR8 siendo R8 un grupo hidroxilo, piridinilmetilo o fenilmetilo; * n es igual a 1 ó 2; * A es un ciclo aromático, eventualmente sustituido por uno dos átomos de halógeno, uno o dos grupos alquilo, lineales o ramificados que comprenden de 1 a 4 átomos de carbono, por un grupo nitro, por un grupo COOR6 , siendo R6 como definido en lo que precede, por uno o dos grupos alcoxi lineales o ramificados que comprenden de 1 a 6 átomos de carbono, o por un grupo metiléndioxi; * X es CH, O ó N; e * Y es CH2 , O ó S, en forma de enantiómeros puros o de mezclas de enantiómeros, incluidas las mezclas racémicas, y las sales que resultan de su adición a ácidos y a bases farmacéuticamente aceptables.Azacycloalkane derivatives characterized by having the following formula (I): in which: * R1 and R2, which may be identical or different from each other, each represent a hydrogen atom, a linear, branched or cyclic alkyl group comprising from 1 to 6 carbon atoms, or a phenyl group optionally substituted by a linear or branched alkyl group comprising from 1 to 6 carbon atoms, by one or two halogen atoms or by a COOR6 group, R6 being an atom hydrogen or a linear or branched alkyl group comprising 1 to 6 carbon atoms; or R1 and R2 together form an oxo group; * R3 represents a hydrogen atom or a linear or branched alkyl group comprising 1 to 4 carbon atoms, or R3 forms a methylene group; * R4 represents an aromatic group chosen from a phenyl, naphthyl or pyridinyl group, optionally substituted by a linear or branched alkyl group comprising from 1 to 6 carbon atoms, by one or two halogen atoms, by a nitro group, or by a COOR6 group with R6 as defined above; or, when R3 forms a methylene group, then R4 represents a phenylene group one of whose carbon atoms is linked to Y and another of whose carbon atoms, adjacent to the one just mentioned, is linked to said methylene group; * R5 is either a group OR7 where R7 is a hydrogen atom or a benzyl group, is an N4 -methyl-piperazinyl group, is still an NHR8 group where R8 is a hydroxyl, pyridinylmethyl or phenylmethyl group; * n is equal to 1 or 2; * A is an aromatic cycle, optionally substituted by one two halogen atoms, one or two linear or branched alkyl groups comprising 1 to 4 carbon atoms, by a nitro group, by a COOR6 group, R6 being as defined in the foregoing, by one or two linear or branched alkoxy groups comprising 1 to 6 carbon atoms, or by a methylenedioxy group; * X is CH, O or N; and * Y is CH2, O or S, in the form of pure enantiomers or mixtures of enantiomers, including racemic mixtures, and the salts resulting from their addition to pharmaceutically acceptable acids and bases.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9505260A FR2733750B1 (en) | 1995-05-03 | 1995-05-03 | DERIVATIVES OF GAMMA-OXO-ALPHA- (PHENYLMETHYL) -5,6- DIHYDRO-4H-THIENO (3,4-C) PYRROLE-5-BUTANOIQUE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4750652A1 true CO4750652A1 (en) | 1999-03-31 |
Family
ID=9478644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO96021765A CO4750652A1 (en) | 1995-05-03 | 1996-05-02 | DERIVATIVES OF AZACICLOALCANOS, ITS PREPARATION AND ITS APPLICATIONS IN THERAPEUTICS |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5869518A (en) |
| EP (1) | EP0823912A1 (en) |
| JP (1) | JPH11504913A (en) |
| KR (1) | KR19990008276A (en) |
| AR (1) | AR001838A1 (en) |
| AU (1) | AU699120B2 (en) |
| BG (1) | BG102015A (en) |
| BR (1) | BR9608309A (en) |
| CA (1) | CA2220015A1 (en) |
| CO (1) | CO4750652A1 (en) |
| CZ (1) | CZ346697A3 (en) |
| EE (1) | EE9700288A (en) |
| FR (1) | FR2733750B1 (en) |
| HU (1) | HUP9903886A3 (en) |
| IL (1) | IL118119A0 (en) |
| NO (1) | NO975020L (en) |
| NZ (1) | NZ307230A (en) |
| PL (1) | PL323177A1 (en) |
| SK (1) | SK147897A3 (en) |
| TR (1) | TR199701287T1 (en) |
| WO (1) | WO1996034870A1 (en) |
| ZA (1) | ZA963485B (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998040385A1 (en) * | 1997-03-07 | 1998-09-17 | Novo Nordisk A/S | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE |
| US6177443B1 (en) | 1997-03-07 | 2001-01-23 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use |
| WO1999045013A1 (en) * | 1998-03-06 | 1999-09-10 | Novo Nordisk A/S | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES |
| FR2777566B1 (en) | 1998-04-15 | 2003-02-21 | Synthelabo | AZACYCLOALCANE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
| FR2779428B1 (en) * | 1998-06-03 | 2001-05-18 | Synthelabo | OXO-AZACYCLOALCAN DERIVATIVES, THEIR PREPARATIONS AND THEIR THERAPEUTIC APPLICATIONS |
| AU5154699A (en) * | 1998-09-02 | 2000-03-27 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno(2,3-c)pyridine derivatives |
| US6090797A (en) * | 1998-09-02 | 2000-07-18 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno(2,3-C)pyridine derivatives |
| FR2793411B1 (en) * | 1999-05-11 | 2001-06-29 | Synthelabo | USE OF SUCCINIC ACID DERIVATIVES FOR OBTAINING A MEDICAMENT FOR THE TREATMENT OF INFLAMMATION |
| PT1088824E (en) * | 1999-09-30 | 2004-04-30 | Pfizer Prod Inc | BLYCYLIC PYRROLYL-AMIDES AS GLYCOGENE-PHOSPHORYLASE INHIBITORS |
| US6797820B2 (en) | 1999-12-17 | 2004-09-28 | Vicuron Pharmaceuticals Inc. | Succinate compounds, compositions and methods of use and preparation |
| AR036053A1 (en) | 2001-06-15 | 2004-08-04 | Versicor Inc | N-FORMIL-HYDROXYLAMINE COMPOUNDS, A PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS |
| WO2002102791A1 (en) * | 2001-06-15 | 2002-12-27 | Vicuron Pharmaceuticals Inc. | Pyrrolidine bicyclic compounds |
| US20090312470A1 (en) * | 2008-06-11 | 2009-12-17 | Ferro Corporation | Asymmetric Cyclic Diester Compounds |
| US20100113664A1 (en) * | 2008-06-11 | 2010-05-06 | Ferro Corporation | Asymmetric Cyclic Diester Compounds |
| DK2350093T3 (en) * | 2008-10-24 | 2012-11-12 | Gruenenthal Gmbh | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2 / 3 modulators for the treatment of pain, epilepsy and urinary incontinence. |
| US9302989B2 (en) | 2010-11-15 | 2016-04-05 | Abbvie Inc. | NAMPT and rock inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3190950A (en) * | 1961-03-13 | 1965-06-22 | Acf Ind Inc | Pictorial position display |
| US3706810A (en) * | 1970-09-15 | 1972-12-19 | American Cyanamid Co | N-morpholinoalkyl-thieno(3,2-b)pyrrole-5-carboxamides |
| ZA821020B (en) * | 1981-02-18 | 1983-10-26 | Thomae Gmbh Dr K | Azepine derivatives, process for their preparation and pharmaceutical compositions thereof |
| FR2537974A1 (en) * | 1982-12-16 | 1984-06-22 | Adir | NOVEL THIENO (2,3-B) PYRROLE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME |
| FR2571723B1 (en) * | 1984-10-12 | 1988-08-26 | Lipha | THIENO AND FURO- (2,3-C) PYRROLES DERIVATIVES, METHODS OF PREPARATION AND MEDICAMENTS CONTAINING THEM |
| FR2652579B1 (en) * | 1989-10-02 | 1992-01-24 | Sanofi Sa | DERIVATIVES OF 2-HYDROXY THIOPHENE AND FURANNE CONDENSED WITH A NITROGEN CYCLE, ON THE PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION. |
| FR2676446B1 (en) * | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | NOVEL THIOPYRANOPYRROLE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| EP0599697A1 (en) * | 1992-11-24 | 1994-06-01 | Synthelabo | Pyrrole derivatives, their preparation and application in therapy |
| FR2719844B1 (en) * | 1994-05-10 | 1996-06-07 | Synthelabo | 5,6-dihydro-4h-thieno [3,4-c] pyrrole derivatives, their preparation and their therapeutic use. |
-
1995
- 1995-05-03 FR FR9505260A patent/FR2733750B1/en not_active Expired - Fee Related
-
1996
- 1996-04-12 NZ NZ307230A patent/NZ307230A/en unknown
- 1996-04-12 TR TR97/01287T patent/TR199701287T1/en unknown
- 1996-04-12 JP JP8533065A patent/JPH11504913A/en active Pending
- 1996-04-12 PL PL96323177A patent/PL323177A1/en unknown
- 1996-04-12 EE EE9700288A patent/EE9700288A/en unknown
- 1996-04-12 CZ CZ973466A patent/CZ346697A3/en unknown
- 1996-04-12 SK SK1478-97A patent/SK147897A3/en unknown
- 1996-04-12 WO PCT/FR1996/000555 patent/WO1996034870A1/en not_active Application Discontinuation
- 1996-04-12 CA CA002220015A patent/CA2220015A1/en not_active Abandoned
- 1996-04-12 US US08/945,576 patent/US5869518A/en not_active Expired - Fee Related
- 1996-04-12 BR BR9608309A patent/BR9608309A/en not_active Application Discontinuation
- 1996-04-12 HU HU9903886A patent/HUP9903886A3/en unknown
- 1996-04-12 KR KR1019970707802A patent/KR19990008276A/en not_active Application Discontinuation
- 1996-04-12 AU AU56520/96A patent/AU699120B2/en not_active Ceased
- 1996-04-12 EP EP96913576A patent/EP0823912A1/en not_active Withdrawn
- 1996-05-02 AR AR33637996A patent/AR001838A1/en unknown
- 1996-05-02 CO CO96021765A patent/CO4750652A1/en unknown
- 1996-05-02 ZA ZA963485A patent/ZA963485B/en unknown
- 1996-05-02 IL IL11811996A patent/IL118119A0/en unknown
-
1997
- 1997-10-31 NO NO975020A patent/NO975020L/en unknown
- 1997-11-03 BG BG102015A patent/BG102015A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5869518A (en) | 1999-02-09 |
| FR2733750A1 (en) | 1996-11-08 |
| AU699120B2 (en) | 1998-11-19 |
| TR199701287T1 (en) | 1998-03-21 |
| IL118119A0 (en) | 1996-09-12 |
| PL323177A1 (en) | 1998-03-16 |
| HUP9903886A2 (en) | 2000-03-28 |
| FR2733750B1 (en) | 1997-06-13 |
| EE9700288A (en) | 1998-04-15 |
| JPH11504913A (en) | 1999-05-11 |
| NZ307230A (en) | 1998-11-25 |
| KR19990008276A (en) | 1999-01-25 |
| BR9608309A (en) | 1999-01-26 |
| WO1996034870A1 (en) | 1996-11-07 |
| ZA963485B (en) | 1996-11-25 |
| HUP9903886A3 (en) | 2000-04-28 |
| AU5652096A (en) | 1996-11-21 |
| NO975020D0 (en) | 1997-10-31 |
| MX9708322A (en) | 1998-06-28 |
| CA2220015A1 (en) | 1996-11-07 |
| NO975020L (en) | 1998-01-05 |
| EP0823912A1 (en) | 1998-02-18 |
| CZ346697A3 (en) | 1998-02-18 |
| AR001838A1 (en) | 1997-12-10 |
| SK147897A3 (en) | 1998-05-06 |
| BG102015A (en) | 1998-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO4750652A1 (en) | DERIVATIVES OF AZACICLOALCANOS, ITS PREPARATION AND ITS APPLICATIONS IN THERAPEUTICS | |
| PE20050015A1 (en) | DERIVATIVES (3-OXO-MORFOLIN-4-IL) -PHENYLAMIDE AS INHIBITORS OF COAGULATION FACTORS AND INTERMEDIARY COMPOUNDS IN THEIR PREPARATION | |
| CO5140119A1 (en) | 3-SUBSTITUTE-N- (IET) ARILALQUIL-PIRROLIDINAS | |
| FR2676443B1 (en) | NOVEL PERHYDROISOINDOLE DERIVATIVES AND THEIR PREPARATION. | |
| HUP0000449A2 (en) | N-subsituted dioxothiazolidylbenzamide derivatives and process for producing the same | |
| AR031597A1 (en) | PIPERIDINE COMPOUNDS, A PROCESS FOR PREPARATION, PHARMACEUTICAL COMPOSITIONS, AND THE USE OF SUCH COMPOUNDS FOR THE MANUFACTURE OF A MEDICINAL PRODUCT FOR USE AS CCR-3 INHIBITORS | |
| CO4700298A1 (en) | DERIVATIVES OF 3-PHENYLISOKINOLEIN-1 (2H) -ONE, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS | |
| ES2052917T3 (en) | PIPERIDINE DERIVATIVES. | |
| DK1086096T3 (en) | Benzamides with tetrahydrofuranyloxy substituents as inhibitors of phosphodiesterase 4 | |
| NO840595L (en) | PROCEDURE FOR MANUFACTURE OF NEW CARBACYCLINES | |
| ES2177275T3 (en) | DERIVATIVES OF OXADIAZOLINE AND ITS USE AS INSECTICIDES. | |
| DE59606057D1 (en) | METHOD FOR PRODUCING DIHYDROXYPYRIMIDINE DERIVATIVES | |
| ES2056194T3 (en) | ANTIDEPRESSIVE TETRACICLIC COMPOUNDS. | |
| CO4520266A1 (en) | DERIVED FROM 1,3-OXAZIN-4-ONA, THE HERBICIDE CONTAINING IT AND THE INTERMEDIATE PRODUCTS TO PREPARE IT | |
| DE69322067D1 (en) | METHOD FOR THE ENZYMATIC PRODUCTION OF AROMATIC SUBSTANCES | |
| AR009105A1 (en) | DERIVATIVES OF N- (BENZOTIAZOL-2-IL) PIPERIDINE-1-ETHANAMINE, ITS PREPARATION AND APPLICATION IN THERAPEUTICS | |
| HUP0301258A2 (en) | Thrombin inhibitors comprising an aminoisoquinoline group and their use for preparation of pharmaceutical compositions | |
| ES2111197T3 (en) | 3,4-DIOXI-1,2,5-TIADIAZOLES IN PART USEFUL AS FUNGICIDES. | |
| ATE63555T1 (en) | DISSYMMETRIC 1,4-DIHYDROPYRIDINE-3,5DICARBONS|URE DERIVATIVES, METHOD OF MANUFACTURE AND USE IN THERAPEUTICS. | |
| ES2059767T3 (en) | DERIVATIVE OF 1,4-DIHYDROPYRIDINE. | |
| ZA88208B (en) | Sweetening agents derived from guanidinoacetic and ethanamidinoacetic acids,process for sweetening various products,and compositions containing such sweetening agents | |
| ATE449063T1 (en) | METHOD FOR PRODUCING BETA-HYDROXYALKYLAMIDES | |
| CO4890850A1 (en) | DERIVATIVES OF 6-PIRROLIDIN-2-ILPIRIDINAS, ITS REPAIR AND PREPARATION IN THERAPEUTICS. | |
| ATE253125T1 (en) | METHOD FOR PRODUCING OPTICALLY ACTIVE 1-AMINO-4-(HYDROXYMETHYL)-CYCLOPENT-2-ENDER DERIVATIVES | |
| BG60248B1 (en) | METHOD FOR THE PREPARATION OF PHENOXYETHYLAMINE DERIVATIVES |