CO2023008892A2 - Combinación farmacéutica de un corticosteroide y un antihistamínico para el tratamiento y control del componente inflamatorio de procesos alérgicos - Google Patents

Combinación farmacéutica de un corticosteroide y un antihistamínico para el tratamiento y control del componente inflamatorio de procesos alérgicos

Info

Publication number
CO2023008892A2
CO2023008892A2 CONC2023/0008892A CO2023008892A CO2023008892A2 CO 2023008892 A2 CO2023008892 A2 CO 2023008892A2 CO 2023008892 A CO2023008892 A CO 2023008892A CO 2023008892 A2 CO2023008892 A2 CO 2023008892A2
Authority
CO
Colombia
Prior art keywords
treatment
antihistamine
corticosteroid
control
pharmaceutical combination
Prior art date
Application number
CONC2023/0008892A
Other languages
English (en)
Inventor
Martinez Cecilia Jannette Muñoz
Salazar Claudia Delfina Farfán
León Sixto Serafín Espinoza
Canudas Jorge Alejandro González
Rubio Paola Yazmín Ollervides
Original Assignee
Laboratorios Silanes S A De C V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Silanes S A De C V filed Critical Laboratorios Silanes S A De C V
Publication of CO2023008892A2 publication Critical patent/CO2023008892A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

La presente invención combina en una sola unidad de dosificación los fármacos desloratadina y betametasona, lo cual, representa un conjunto de importantes retos tecnológicos debido a las propiedades fisicoquímicas y a la diferencia en dosis para garantizar la obtención de un producto estable para el tratamiento de procesos alérgicos e inflamatorios en un sujeto.
CONC2023/0008892A 2020-12-04 2023-07-04 Combinación farmacéutica de un corticosteroide y un antihistamínico para el tratamiento y control del componente inflamatorio de procesos alérgicos CO2023008892A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/MX2020/050048 WO2022119428A1 (es) 2020-12-04 2020-12-04 Combinación farmacéutica de un corticosteroide y un antihistamínico para el tratamiento y control del componente inflamatorio de procesos alérgicos

Publications (1)

Publication Number Publication Date
CO2023008892A2 true CO2023008892A2 (es) 2023-08-18

Family

ID=81853419

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2023/0008892A CO2023008892A2 (es) 2020-12-04 2023-07-04 Combinación farmacéutica de un corticosteroide y un antihistamínico para el tratamiento y control del componente inflamatorio de procesos alérgicos

Country Status (7)

Country Link
US (1) US20240024307A1 (es)
EP (1) EP4230211A1 (es)
CA (1) CA3199160A1 (es)
CO (1) CO2023008892A2 (es)
DO (1) DOP2023000093A (es)
MX (1) MX2022015335A (es)
WO (1) WO2022119428A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102022006848A2 (pt) * 2022-04-08 2023-10-24 Eurofarma Laboratorios S.A. Uso de prednisolona ou seus sais farmacêuticos ativos em uma composição farmacêutica, composição farmacêutica, seu processo de preparação e seu uso

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053865A (en) 1958-03-19 1962-09-11 Merck & Co Inc Novel 16-alkyl and 16-alkylene steroids and processes
HU194864B (en) 1984-02-15 1988-03-28 Schering Corp Process for production of 8-chlor-6,11-dihydro-11-(4-piperidilidene)-5h-benzo (5,6)-cyclo-hepta (1,2-b) pyridine and its salts
DE19729516C2 (de) 1997-07-10 1999-04-22 Georg Wiegner Pumpe zum dosierten Austragen von flüssigen, gelartigen oder viskosen Substanzen
WO2000051605A1 (en) 1999-03-01 2000-09-08 Schering Corporation Compositions and methods for treating atopic dermatitis, angioedema and other disorders using antihistamines and glucocorticoids
EP1696881A2 (en) 2003-12-23 2006-09-06 Sun Pharmaceutical Industries Limited Stable oral composition
EA200702049A1 (ru) 2005-03-23 2008-02-28 Элан Фарма Интернэшнл Лтд. Композиции наночастиц кортикостероидов с антигистаминами
US9592241B2 (en) * 2011-12-27 2017-03-14 Cmpd Licensing, Llc Silicone-based composition for skin treatment

Also Published As

Publication number Publication date
WO2022119428A1 (es) 2022-06-09
CA3199160A1 (en) 2022-06-09
EP4230211A1 (en) 2023-08-23
DOP2023000093A (es) 2023-06-15
US20240024307A1 (en) 2024-01-25
MX2022015335A (es) 2023-01-11

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