CO2021000763A2 - Stability of vitamin d in b-hydroxy-b-methylbutyrate (hmb) - Google Patents

Stability of vitamin d in b-hydroxy-b-methylbutyrate (hmb)

Info

Publication number
CO2021000763A2
CO2021000763A2 CONC2021/0000763A CO2021000763A CO2021000763A2 CO 2021000763 A2 CO2021000763 A2 CO 2021000763A2 CO 2021000763 A CO2021000763 A CO 2021000763A CO 2021000763 A2 CO2021000763 A2 CO 2021000763A2
Authority
CO
Colombia
Prior art keywords
vitamin
hmb
methylbutyrate
hydroxy
stability
Prior art date
Application number
CONC2021/0000763A
Other languages
Spanish (es)
Inventor
John Rathmacher
Martin Purpura
Original Assignee
Metabolic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/038948 external-priority patent/WO2020263229A1/en
Application filed by Metabolic Tech Inc filed Critical Metabolic Tech Inc
Publication of CO2021000763A2 publication Critical patent/CO2021000763A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

La presente invención proporciona una composición que comprende una formulación ácida que contiene P-hidroxi-P-metilbutirato (HMB), preferiblemente en la forma ácida libre, Vitamina D y un excipiente estabilizador, en donde la vitamina D se estabiliza contra la degradación.The present invention provides a composition comprising an acid formulation containing P-hydroxy-P-methylbutyrate (HMB), preferably in the free acid form, Vitamin D and a stabilizing excipient, wherein the vitamin D is stabilized against degradation.

CONC2021/0000763A 2018-06-25 2021-01-25 Stability of vitamin d in b-hydroxy-b-methylbutyrate (hmb) CO2021000763A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862689305P 2018-06-25 2018-06-25
PCT/US2019/038948 WO2020263229A1 (en) 2019-06-25 2019-06-25 STABILITY OF VITAMIN D IN β-HYDROXY- β-METHYLBUTYRATE (HMB)

Publications (1)

Publication Number Publication Date
CO2021000763A2 true CO2021000763A2 (en) 2021-04-08

Family

ID=75293630

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2021/0000763A CO2021000763A2 (en) 2018-06-25 2021-01-25 Stability of vitamin d in b-hydroxy-b-methylbutyrate (hmb)

Country Status (3)

Country Link
EP (1) EP3836803A4 (en)
BR (1) BR112020026621A2 (en)
CO (1) CO2021000763A2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060019933A1 (en) * 2004-07-22 2006-01-26 David Boardman Process for preparing stabilized vitamin D
SG192692A1 (en) * 2011-02-07 2013-09-30 Abbott Lab Nutritional products comprising beta-hydroxy-beta-methylbutyrate
CN105578901A (en) * 2014-03-14 2016-05-11 代谢科技有限公司 Liquids and foodstuffs containing beta-hydroxy-beta-methylbutyrate (hmb) in free acid form

Also Published As

Publication number Publication date
EP3836803A4 (en) 2022-07-20
EP3836803A1 (en) 2021-06-23
BR112020026621A2 (en) 2021-03-30

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