CO2021000158A2 - Pharmaceutical composition containing a peptide - Google Patents
Pharmaceutical composition containing a peptideInfo
- Publication number
- CO2021000158A2 CO2021000158A2 CONC2021/0000158A CO2021000158A CO2021000158A2 CO 2021000158 A2 CO2021000158 A2 CO 2021000158A2 CO 2021000158 A CO2021000158 A CO 2021000158A CO 2021000158 A2 CO2021000158 A2 CO 2021000158A2
- Authority
- CO
- Colombia
- Prior art keywords
- pharmaceutical composition
- peptide
- composition containing
- composition
- irritable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a una composición farmacéutica estable para administración oral que comprende linaclotida o sales farmacéuticamente aceptables de la misma y un vehículo. Asimismo, se proporcionan métodos para preparar y usar la composición. En particular, la composición se puede usar en el tratamiento de trastornos gastrointestinales, tales como estreñimiento crónico y síndrome del intestino irritable. irritable.The present invention relates to a stable pharmaceutical composition for oral administration comprising linaclotide or pharmaceutically acceptable salts thereof and a carrier. Also provided are methods for preparing and using the composition. In particular, the composition can be used in the treatment of gastrointestinal disorders, such as chronic constipation and irritable bowel syndrome. irritable.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201811025533 | 2018-07-09 | ||
PCT/IB2019/000716 WO2020012243A2 (en) | 2018-07-09 | 2019-07-08 | Pharmaceutical composition containing a peptide |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2021000158A2 true CO2021000158A2 (en) | 2021-01-18 |
Family
ID=68165587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2021/0000158A CO2021000158A2 (en) | 2018-07-09 | 2021-01-12 | Pharmaceutical composition containing a peptide |
Country Status (6)
Country | Link |
---|---|
AR (1) | AR115724A1 (en) |
BR (1) | BR112021000201A2 (en) |
CL (1) | CL2021000022A1 (en) |
CO (1) | CO2021000158A2 (en) |
MX (1) | MX2021000312A (en) |
WO (1) | WO2020012243A2 (en) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007033427A1 (en) | 2005-09-23 | 2007-03-29 | Metabolic Pharmaceuticals Limited | Stabilisation of peptides with basic amino acids |
MX2020005326A (en) | 2008-08-15 | 2022-03-03 | Ironwood Pharmaceuticals Inc | Linaclotide-containing formulations for oral administration. |
EP2238979A1 (en) * | 2009-04-06 | 2010-10-13 | LEK Pharmaceuticals d.d. | Active pharmaceutical ingredient adsorbed on solid support |
US9616097B2 (en) * | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
JP2016521249A (en) | 2012-07-12 | 2016-07-21 | フォレスト ラボラトリーズ ホールディングス リミテッド | Linaclotide composition |
WO2016024291A1 (en) | 2014-08-11 | 2016-02-18 | Sun Pharmaceutical Industries Ltd. | Linaclotide stable composition |
EP3233059A1 (en) * | 2014-12-19 | 2017-10-25 | Synthon B.V. | Pharmaceutical composition comprising amorphous lenalidomide |
-
2019
- 2019-07-08 WO PCT/IB2019/000716 patent/WO2020012243A2/en active Application Filing
- 2019-07-08 BR BR112021000201-4A patent/BR112021000201A2/en unknown
- 2019-07-08 MX MX2021000312A patent/MX2021000312A/en unknown
- 2019-07-10 AR ARP190101936A patent/AR115724A1/en unknown
-
2021
- 2021-01-06 CL CL2021000022A patent/CL2021000022A1/en unknown
- 2021-01-12 CO CONC2021/0000158A patent/CO2021000158A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
AR115724A1 (en) | 2021-02-17 |
CL2021000022A1 (en) | 2021-07-19 |
WO2020012243A3 (en) | 2020-03-05 |
MX2021000312A (en) | 2021-06-08 |
BR112021000201A2 (en) | 2021-08-10 |
WO2020012243A2 (en) | 2020-01-16 |
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