CO2020004180A2 - Mezcla en estado metaestable - Google Patents

Mezcla en estado metaestable

Info

Publication number
CO2020004180A2
CO2020004180A2 CONC2020/0004180A CO2020004180A CO2020004180A2 CO 2020004180 A2 CO2020004180 A2 CO 2020004180A2 CO 2020004180 A CO2020004180 A CO 2020004180A CO 2020004180 A2 CO2020004180 A2 CO 2020004180A2
Authority
CO
Colombia
Prior art keywords
controller
spores
holding tank
valves
nutrients
Prior art date
Application number
CONC2020/0004180A
Other languages
English (en)
Inventor
Jordan E Church
Gabriel F K Everett
Charles J Greenwald
Christopher J Laney
Michael Paloian
Judith G Pruitt
Amanda K Rosmarin
Michael J Schuster
Original Assignee
NCH Life Sciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NCH Life Sciences LLC filed Critical NCH Life Sciences LLC
Publication of CO2020004180A2 publication Critical patent/CO2020004180A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/22—Means for packing or storing viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N3/00—Spore forming or isolating processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/0015—Feeding of the particles in the reactor; Evacuation of the particles out of the reactor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/008—Details of the reactor or of the particulate material; Processes to increase or to retard the rate of reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Computer Hardware Design (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Se describen sistemas de mezclado de incubación de esporas en estado metaestable. Un ejemplo del sistema incluye un contenedor de esporas para almacenar esporas, un contenedor de nutrientes, una disposición de válvulas y tubos, una bomba alternante, a tubo de mezclado, y un tanque de conservación. En una fase de extracción del sistema, un controlador puede controlar la bomba alternante para extraer un volumen proporcional de las esporas, los nutrientes, y agua a través de las válvulas y tubos. Durante una fase de expulsión del sistema, el controlador puede controlar válvulas de control de flujo para dirigir las esporas, nutrientes, y agua a través del tubo de mezclado y dentro del tanque de conservación. El controlador puede dirigir también un calentador para calentar la mezcla en el tanque de conservación a una temperatura predeterminada. Una vez que la mezcla alcanza la temperatura, el controlador puede dirigir también el sistema a través de una cantidad de otras fases de operación, que incluyen fases de enfriado y purgado.
CONC2020/0004180A 2017-10-04 2020-04-03 Mezcla en estado metaestable CO2020004180A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762568007P 2017-10-04 2017-10-04
US16/151,165 US11155780B2 (en) 2017-10-04 2018-10-03 Metastable state mixing
PCT/US2018/054389 WO2019070992A1 (en) 2017-10-04 2018-10-04 MIXING IN THE METASTABLE STATE

Publications (1)

Publication Number Publication Date
CO2020004180A2 true CO2020004180A2 (es) 2020-04-24

Family

ID=65897726

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2020/0004180A CO2020004180A2 (es) 2017-10-04 2020-04-03 Mezcla en estado metaestable

Country Status (10)

Country Link
US (2) US11155780B2 (es)
EP (1) EP3691776A4 (es)
CN (1) CN111491721A (es)
BR (1) BR112020006602B1 (es)
CA (1) CA3077364C (es)
CO (1) CO2020004180A2 (es)
MX (1) MX2020007107A (es)
NZ (1) NZ763367A (es)
PH (1) PH12020550188A1 (es)
WO (1) WO2019070992A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3110499A1 (en) * 2018-08-27 2020-03-05 NCH Life Sciences LLC System and method of metastable state mixing
US11401500B2 (en) 2018-08-29 2022-08-02 Nch Corporation System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications
WO2021159068A1 (en) 2020-02-06 2021-08-12 Nch Corportion Composition and method of using germinative compounds in probiotics for inflammation reduction in humans

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2565598B1 (fr) 1984-06-06 1986-10-03 Inst Nat Sante Rech Med Appareil modulaire pour la culture cellulaire
CA2434032A1 (en) 2001-01-09 2002-07-18 Wastewater Biological Solutions Corp. Apparatus and method for biological treatment of environmental contaminants and waste
MXPA06007921A (es) 2004-02-06 2007-03-07 Ericsson Telefon Ab L M Transmision entre una red ceular y una red de acceso de radio sin licencia utilizando un identificador individual para todos los puntos de acceso.
KR100865682B1 (ko) 2006-07-12 2008-10-29 한양대학교 산학협력단 바실러스 군집 포자 배양조
US20080032396A1 (en) 2006-08-02 2008-02-07 Becton, Dickinson And Company Bioreactor and Method
AU2008269201B2 (en) 2007-06-21 2011-08-18 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
US7797899B2 (en) * 2007-12-07 2010-09-21 Nox-Crete Products Group Temporary floor joint filler
US20090242173A1 (en) 2008-03-25 2009-10-01 Peter Mitchell Temperature control system
US9550971B2 (en) * 2009-04-14 2017-01-24 Therapeutic Proteins International, LLC Universal bioreactors and methods of use
US8728550B2 (en) 2010-05-07 2014-05-20 Menon Renewable Resources, Inc. Animal meal that includes fungal biomass
US9334471B2 (en) 2010-05-28 2016-05-10 Gea Brewery Systems Gmbh Method for accelerated fermentation and device for mixing a tank content
US8933383B2 (en) * 2010-09-01 2015-01-13 The United States Of America As Represented By The Secretary Of The Army Method and apparatus for correcting the trajectory of a fin-stabilized, ballistic projectile using canards
CN104745464B (zh) 2013-12-31 2016-09-14 牛刚 全自动微生物检测富集系统及其富集方法
WO2017079682A1 (en) 2015-11-04 2017-05-11 Thrive Bioscience, Inc. Automated cell culture incubators comprising selectively permeable cell culture vessel storage compartments
WO2017106853A1 (en) * 2015-12-17 2017-06-22 Nch Corporation In situ biomass generator with automated disinfection
US20190002819A1 (en) 2015-12-28 2019-01-03 Novozymes Bioag A/S Heat priming of bacterial spores
US11292999B2 (en) 2016-08-30 2022-04-05 Finesse Solutions, Inc. Bioreactor with multiple coupled vessels

Also Published As

Publication number Publication date
US20220041978A1 (en) 2022-02-10
CA3077364A1 (en) 2019-04-11
US11155780B2 (en) 2021-10-26
US20190100723A1 (en) 2019-04-04
BR112020006602A2 (pt) 2020-10-06
CA3077364C (en) 2022-08-30
EP3691776A1 (en) 2020-08-12
BR112020006602B1 (pt) 2022-06-07
NZ763367A (en) 2022-01-28
PH12020550188A1 (en) 2021-03-01
WO2019070992A1 (en) 2019-04-11
CN111491721A (zh) 2020-08-04
EP3691776A4 (en) 2021-06-23
MX2020007107A (es) 2020-11-25
US11773366B2 (en) 2023-10-03

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