CN2905071Y - Biological amnion - Google Patents
Biological amnion Download PDFInfo
- Publication number
- CN2905071Y CN2905071Y CN 200620040896 CN200620040896U CN2905071Y CN 2905071 Y CN2905071 Y CN 2905071Y CN 200620040896 CN200620040896 CN 200620040896 CN 200620040896 U CN200620040896 U CN 200620040896U CN 2905071 Y CN2905071 Y CN 2905071Y
- Authority
- CN
- China
- Prior art keywords
- bioamnion
- surface unit
- basement membrane
- concave
- layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000001691 amnion Anatomy 0.000 title abstract description 14
- 210000002469 basement membrane Anatomy 0.000 claims abstract description 18
- 210000000981 epithelium Anatomy 0.000 claims abstract description 15
- 239000002344 surface layer Substances 0.000 claims description 14
- 239000010410 layer Substances 0.000 claims description 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 229920002160 Celluloid Polymers 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
The utility model discloses a biological amnion which one side is an epithelium layer and the other side is a basement membrane surface; one is a convex surface structure and the other one is a concave surface structure in the epithelium layer and the basement membrane surface. The biological amnion with the technology above can identify the epithelium layer and the basement membrane surface simply and directly, and usage is very convenient, which is only to put the basement membrane surface on the ocular surface before using.
Description
Technical field
This utility model relates to a kind of bioamnion, relates in particular to a kind of bioamnion for the identification positive and negative.
Background technology
Bioamnion has been widely used in the auxiliary treatment of burn wound and ophthalmic diseases both at home and abroad, its curative effect highly significant clinically as a kind of new biomaterial.In the treatment of ophthalmic diseases, the substrate face of bioamnion must be attached to when using bioamnion on the eye table, which face that must correctly identify amniotic membrane preparations when therefore using is the substrate face.
Existing a kind of on the market in recent years bioamnion goods after lyophilisation is handled are subjected to ophthalmic diseases patient and ophthalmologist's favor very much.In the process of producing this kind amniotic membrane preparations, the substrate face of amniotic membrane is attached to (the amniotic membrane cuticular cellulose is last) on the celluloid filter paper.After will soaking several minutes with normal saline before using, earlier amniotic membrane is peeled off from filter paper, will be attached on the eye table from this one side (basement membrane surface layer) that filter paper is peeled off again.In this process, the rehydration time of amniotic membrane is long, with filter paper difficulty separate, easily curl, and amniotic membrane is again water white thin film, the positive and negative ratio is easier to obscure, also relatively more difficult when pasting amniotic membrane, so just reduced the efficient of operation, might bring negative influence to hospital and patient, it is not too convenient to use.
Novel content
The purpose of this utility model is, a kind of bioamnion is provided, and is difficult to identification to solve prior biological amniotic membrane positive and negative, and operation efficient is low, awkward technical problem.
In order to achieve the above object, the technical solution of the utility model is as follows:
A kind of bioamnion, one side is an epithelium layer, another side is the basement membrane surface layer; Be convex configuration one of in described epithelium layer and the basement membrane surface layer, another is a concave structure.
Adopt the bioamnion of said structure, very the basement membrane surface layer and the epithelium layer of simple, intuitive ground identification bioamnion only need before using the basement membrane surface layer of amniotic membrane is attached on the eye table, and be very easy to use.
Described epithelium layer is a concave structure, and described basement membrane surface layer is a convex configuration.Like this, concave surface is convenient to drip upward normal saline stitching towards the eye off-balancesheet during use.
Described concave structure is made up of concave surface unit arranged into an array.
Described convex configuration is made up of convex surface unit arranged into an array.
Described convex surface unit and concave surface cell position correspondence, the quantity unanimity.
Described convex surface unit is less than the concave surface unit.
Described convex surface unit and concave surface unit are square.
Description of drawings
Fig. 1 is the structural representation of bioamnion of the present utility model;
Fig. 2 a is the convex surface unit floor map of bioamnion among Fig. 1;
Fig. 2 b is the concave surface unit floor map of bioamnion among Fig. 1.
The specific embodiment
According to Fig. 1, Fig. 2 a and Fig. 2 b, provide preferred embodiment of the present utility model, and described in detail below, enable to understand better function of the present utility model, characteristics.
The structure of bioamnion of the present utility model comprises basement membrane surface layer 1 and epithelium layer 2 as shown in Figure 1.Basement membrane surface layer 1 is a convex configuration, and epithelium layer 2 is a concave structure.Also can be opposite, promptly the basement membrane surface layer is made as concave structure, and epithelium layer is made as convex configuration.
Consult Fig. 1, and in conjunction with Fig. 2 a and Fig. 2 b, convex configuration is made up of plurality of square convex surface unit 11 arranged into an array, concave structure is made up of plurality of square concave surface unit 21 arranged into an array.Convex surface unit 11 is less than concave surface unit 21, and concave surface unit 21 length of sides 4 are 1.8mm, and convex surface unit 11 length of sides 5 are 1.7mm.The center distance 6 of convex surface unit 11 is 2.6mm, and the height 3 of convex surface unit 11 is 2mm.Described convex surface unit 11 and concave surface unit 21 position correspondences, the quantity unanimity.Adopt the bioamnion of said structure, very the basement membrane surface layer 1 and the epithelium layer 2 of simple, intuitive ground identification bioamnion only need before using the basement membrane surface layer 1 of amniotic membrane is attached on the eye table, and epithelium layer 2 is towards the eye off-balancesheet, drip the normal saline stitching again and get final product, very easy to use.
The front provides the description to preferred embodiment, so that any technical staff in this area can use or utilize this utility model.To this preferred embodiment, those skilled in the art can make various modifications or conversion on the basis that does not break away from this utility model principle.For example, the unitary shape of the convex surface of bioamnion of the present utility model can be made different shape, is not only can be square among the embodiment; The unitary concrete size of convex surface unit and concave surface also can according to circumstances be regulated, the size that is not defined as embodiment and is lifted.Should be appreciated that in the description for embodiment only be a kind of preferred embodiment, modification or conversion that this embodiment is made do not break away from protection domain of the present utility model.
Claims (7)
1, a kind of bioamnion, one side is an epithelium layer, another side is the basement membrane surface layer; It is characterized in that, be convex configuration one of in described epithelium layer and the basement membrane surface layer, and another is a concave structure.
2, bioamnion as claimed in claim 1 is characterized in that, described epithelium layer is a concave structure, and described basement membrane surface layer is a convex configuration.
3, bioamnion as claimed in claim 2 is characterized in that, described concave structure is made up of concave surface unit arranged into an array.
4, bioamnion as claimed in claim 3 is characterized in that, described convex configuration is made up of convex surface unit arranged into an array.
5, bioamnion as claimed in claim 4 is characterized in that, described convex surface unit and concave surface cell position correspondence, quantity unanimity.
6, bioamnion as claimed in claim 5 is characterized in that, described convex surface unit is less than the concave surface unit.
7, bioamnion as claimed in claim 6 is characterized in that, described convex surface unit and concave surface unit are square.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620040896 CN2905071Y (en) | 2006-04-07 | 2006-04-07 | Biological amnion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620040896 CN2905071Y (en) | 2006-04-07 | 2006-04-07 | Biological amnion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2905071Y true CN2905071Y (en) | 2007-05-30 |
Family
ID=38113696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200620040896 Expired - Lifetime CN2905071Y (en) | 2006-04-07 | 2006-04-07 | Biological amnion |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2905071Y (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102586175A (en) * | 2011-09-30 | 2012-07-18 | 上海交通大学附属第一人民医院 | Method for culturing human limbal stem cell graft |
| CN103405309A (en) * | 2013-07-29 | 2013-11-27 | 庞希宁 | Biological dressing for anus and crissum postoperation wound surface and preparation method |
| WO2018163400A1 (en) * | 2017-03-10 | 2018-09-13 | 株式会社アムノス | Amniotic membrane piece and method for manufacturing same |
| KR20190104991A (en) * | 2016-11-02 | 2019-09-11 | 옥소젠 코포레이션 | Amniotic tissue grafts and methods of making and using the same |
-
2006
- 2006-04-07 CN CN 200620040896 patent/CN2905071Y/en not_active Expired - Lifetime
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102586175A (en) * | 2011-09-30 | 2012-07-18 | 上海交通大学附属第一人民医院 | Method for culturing human limbal stem cell graft |
| CN103405309A (en) * | 2013-07-29 | 2013-11-27 | 庞希宁 | Biological dressing for anus and crissum postoperation wound surface and preparation method |
| KR20190104991A (en) * | 2016-11-02 | 2019-09-11 | 옥소젠 코포레이션 | Amniotic tissue grafts and methods of making and using the same |
| JP2019536596A (en) * | 2016-11-02 | 2019-12-19 | アクソジェン コーポレーション | Amniotic membrane graft and its preparation and use |
| JP7171588B2 (en) | 2016-11-02 | 2022-11-15 | アクソジェン コーポレーション | Amnion tissue graft and method of preparation and use thereof |
| US11577001B2 (en) | 2016-11-02 | 2023-02-14 | Axogen Corporation | Amnion tissue grafts and methods of preparing and using same |
| KR102514753B1 (en) * | 2016-11-02 | 2023-03-27 | 옥소젠 코포레이션 | Amnion tissue grafts and methods of making and using the same |
| WO2018163400A1 (en) * | 2017-03-10 | 2018-09-13 | 株式会社アムノス | Amniotic membrane piece and method for manufacturing same |
| JPWO2018163400A1 (en) * | 2017-03-10 | 2020-01-16 | 株式会社アムノス | Amniotic membrane piece and method for producing the same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: JIANGXI RUIJI BIO-ENGINEERING TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: MIAO JIUCHANG Effective date: 20131024 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20131024 Address after: 330029 No. 382 Fang Fang Road, Nanchang, Jiangxi Patentee after: Jiangxi Ruiji Bio-Engineering Technology Co., Ltd. Address before: 330029 No. 108 Fang Fang Road, Nanchang, Jiangxi Patentee before: Miao Jiuchang |
|
| CX01 | Expiry of patent term |
Granted publication date: 20070530 |
|
| EXPY | Termination of patent right or utility model |