The specific embodiment
Referring to Fig. 1, the target vessel irradiation positioner 2 of this utility model laser therapeutic apparatus is connected with the casing back side 1 of therapeutic instrument, this junction is positioned at about 2cm place, top of the uppermost laser instrument 9 at the casing back side, and is parallel with one side of casing with the line of nearest laser instrument.Labelling 10 is the security bars that prevent the laser diffusion among the figure.This utility model comprises structures such as a mastoid process 21 and connecting rod, and following two embodiment are arranged:
Embodiment 1: referring to Fig. 2, described connecting rod is a screw rod 5, and screws in the screw of the described casing back side 1 correspondence, screw rod 5 near the location mastoid process 21 part be polished rod, be provided with graduated scale 4 on the surface, be provided with anti-skidding stricture of vagina 3 at the side face of mastoid process along length direction.
Embodiment 2: referring to Fig. 3, described connecting rod is by slide bar 6, and this slide bar vertically slides and inserts in the slide opening of the described casing back side 1 correspondence, is provided with in the inner of slide bar 6 and whenever pushes the mechanism 8 of once alternately stretching out with indentation.At the groove 7 that the outer end of the slide opening at the described casing back side 1 is provided with and described location mastoid process is coincide; On described slide bar 6, be provided with scale 4.The mechanism 8 of stretching out with indentation is conventional structure, as the refill expansion mechanism of expansion ball pen.
The parameter of the design of this utility model radial artery target vessel localizer is according to coming from " compatriots' radial artery moves towards measurement report ", and the statistical procedures effluent south information computing center of the college of traditional Chinese medicine of measurement data provides.
The measuring method and the result (referring to Fig. 4) of radial artery trend:
This group measuring object is totally 342 examples, and measuring method is according to the body surface symbol of " practical anatomical atlas upper limb fascicle " described radial artery, with reference to " the somatometry handbook is measured.
1. be m by 2.5cm place, upper limb elbow band mid point below (being designated as the G point) to the vertical length of rasceta midpoint (being designated as the H point).
2. the line of radial artery along upper limb elbow band mid point below 2.5cm to processus styloideus radii extends downwards and rasceta crossing (being designated as the F point), and the vertical length that F point and H are ordered is n.
3. the angle of the line of the trend of radial artery and elbow band mid point and rasceta mid point is radial artery angle α.
Data statistics is handled and is adopted SPSS 10.0 for Windows statistical softwares to carry out statistical analysis sample average (Mean), standard deviation (Std.Deviation), median (Median), minima (Minimum), maximum (Maximum).
The radial artery angle α that counts according to measurement result between 5~15 degree, sample average (Mean)=9.06 degree, median (Median)=9 degree, minima (Minimum)=5 degree, maximum (Maximum)=15 degree (referring to table 1, table 2 and Fig. 4).
SPSS10.0 statistical result (Statistics module) table 1
The radial artery angle
N Valid Mean Std.Error of Mean Median Std.Deviation Skewness Std.Error of Skewness Kurtosis Std.Error of Kurtosis Range Minimum Maximum | 342 9.06 .13 9.00 2.37 .411 .132 -.262 .263 10 5 15 |
Table 2 zones of different, different sexes and age radial artery angle measurement result
Classification | The example number | Min | Max | x±SD | Med | Range | CI99% |
The zone | The southerner northerner | 166 176 | 6 5 | 15 15 | 9.05±1.99 9.07±2.23 | 9.00 9.00 | 10.00 10.00 | 8.10~9.99 8.72~9.41 |
Sex | The men and women | 150 192 | 6 5 | 15 15 | 9.40±2.28 8.80±1.95 | 10.00 9.00 | 9.00 10.00 | 8.93~9.87 8.34~9.26 |
Age | Young person in middle and old age | 186 156 | 5 6 | 15 15 | 8.58±2.01 9.63±2.05 | 8.50 10.00 | 10.00 10.00 | 8.16~9.01 9.13~10.14 |
Totally | | 342 | 5 | 15 | 9.06±2.37 | 9.00 | 10.00 | 8.10~10.14 |
This utility model is according to the move towards location of human anatomy principle to the irradiation tremulous pulse, as radial artery and body surface projection is the line of 2.5cm place, elbow band mid point fossa cubitalis below to wrist processus styloideus radii, anchor point of this machine and laser instrument are fixed angle (α=9 degree by the radial artery trend on this basis, median Median) arranges, when anchor point is aimed at the processus styloideus radii place, laser is thrown the irradiation speckle and then is covered on the radial artery fully, what effectively solve that prior art exists can't accurately locate arteries and make the problem of effective underexposure, has improved curative effect greatly.
The cardiovascular and cerebrovascular vessel laser therapeutic apparatus of the band target vessel irradiation positioner that use this utility model is made is as follows through the clinical report that two tame provincial, and municipal level hospitals (the 5th Affiliated Hospital of Zhongshan Medical Univ., Henan College Of Traditional Chinese Medicine second Affiliated Hospital) carry out clinical observation:
1 clinical data
1.1 case is included standard and exclusion standard in
1.1.1 case is included standard in
1) hemorheology detects: any one unusual person and 2 in reflection such as whole blood viscosity, plasma viscosity, packed cell volume, erythrocyte aggregation index, Fibrinogen, the erythrocyte sedimentation rate blood hyperviscosity index), 4) two arbitrary unusual persons.
2) lipids detection: any one unusual person in the index of reflection such as T-CHOL (TC), triglyceride (TG), low density lipoprotein, LDL (LDL-C), high density lipoprotein (HDL-C) hyperlipidemia.
3) nail fold microcirculation detects: pipe loop form (comprising definition, pipe loop number, input branch, output branch, pipe loop length), blood fluidised form (comprising flow velocity, erythrocyte aggregation), pipe loop ambient state (comprise ooze out, venous plexus under hemorrhage, the nipple), any one unusual person and 2 in the index of reflection nail fold microcirculation), 4) two each unusual persons.
4) any one unusual person in fasting glucose, the glycolated hemoglobin.
5) state of an illness allow to be observed person more than three months between 20-70 the age.
6) treatment in accordance with regulations can be judged curative effect person.
Possess in above (1), (2), (3), (4) any one and possess (5), (6) person all can be used as and includes object in.
1.1.2 case exclusion standard:
1) the artificial cardiac pacemaker person is installed.
2) implant electronics heart pump or electric physiology support person.
3) person that has the metal implant in the body.
1.1.3 diagnostic criteria
With reference to Ministry of Public Health " new Chinese medicine clinical research guideline ", " ischemic heart desease name and diagnostic criteria ", " clinical disease diagnosis is according to curing the improvement standard ", " diagnostic criteria of CAIM (Chinese Association Of Integrative Medicine) peripheral vascular disease ", " all kinds of cerebrovascular disease diagnosis main points ", " international hypertension alliance (WHO-ISH) Evaluation of Diagnostic Criteria of Hypertension " and " ADA (ADA) diabetes diagnosis new standard ".
1.2 case physical data
1.2.1 the cardiovascular diseases organizes this group and includes cardiovascular patient totally 37 examples that meet the clinical diagnosis standard, male 20 examples, women 17 examples in; Age: 35~72 years old, 52.45 years old mean age.Coronary heart disease 12 examples wherein, myocardial ischemia 8 examples, angina pectoris 7 examples, rheumatic heart disease 5 examples, pulmonary heart disease 5 examples.
1.2.2 this group of cerebrovascular group is included patients with cerebrovascular disease totally 33 examples that meet the clinical diagnosis standard, male 15 examples, women 18 examples in; Age: 44~76 years old, 56.21 years old mean age.Cerebral infarction 7 examples wherein, cerebral thrombosis 6 examples, cerebral arteriosclerosis 4 examples, carotid artery stenosis 5 examples, vascular dementia 3 examples, vertebra base tremulous pulse blood supply insufficiency 6 examples, migraine 2 examples, this group patient's characteristics all have the performance of blood fat, high blood viscosity and cerebral blood supply insufficiency.
1.2.3 this group of peripheral angiopathy group is included peripheral vessels patient totally 15 examples that meet the clinical diagnosis standard, male 10 examples, women 5 examples in; Age: 31~75 years old, 51.75 years old mean age.Varicose veins of the lower extremity 6 examples wherein, thromboangiitis obliterans 5 examples, atherosclerotic occlusive disease 4 examples, deep venous thrombosis shape 2 examples.1.2.4 this group of metabolic syndrome group is included metabolic syndrome patient's totally 35 examples that meet the clinical diagnosis standard in, male's 19 examples, women's 16 examples, minimum 21 years old of age of onset, maximum 66 years old.Diabetes 12 examples wherein, hyperlipidemia 8 examples, hypertension 15 examples.
2 therapeutic schemes
2.1 own control design: adopt the method for designing of self treating cross-reference to carry out clinical observation, the baseline value of treatment Pretesting cardiovascular and cerebrovascular disease, peripheral angiopathy and metabolic syndrome patient's nail fold microcirculation, blood fat, the every index of hemorheology, metabolic syndrome patient increases the baseline value of surveying blood glucose, glycolated hemoglobin index.Check nail fold microcirculation, blood fat, hemorheology, blood glucose, glycolated hemoglobin after treating 3 courses of treatment, the comparison before and after carrying out self treating with baseline value before the treatment.
2.2 Therapeutic Method
During treatment the target vessel localizer at " the cardiovascular and cerebrovascular vessel laser therapeutic apparatus of the band target vessel irradiation positioner that this utility model is made " back is aimed at wrist processus styloideus radii recess, fixing band is fixed on the left finesse, optical maser wavelength 650nm, laser irradiation power is 20mW, the blood vessel irradiation time is each 40 minutes, once a day, treating a week is a course of treatment, finish the back and had a rest 2 days a course of treatment, repeat the next course of treatment again, treat the improvement situation of each clinical indexes of measurement after two courses of treatment.
Whole cases medicines of any blood fat reducing and blood viscosity lowering of during treating, stopping using.
2.3 observation index
2.3.1 nail fold microcirculation inspection: adopt WX-10 type multi-section position micro-circulation scanning tunnelling microscope (the prosperous smooth optical instrument company limited in Xuzhou), to the form integrated value, the fluidised form integrated value is managed 19 weighted product point-score evaluations that indexs adopt PLA General Hospital Tian Niu to teach such as all State integral values.
2.3.2 hemorheology detects patient and takes a blood sample on an empty stomach, anticoagulant heparin adopts vertebral plate method (SABA-PM4000-3 automatic clinical chemistry analyzer, diligent generation Supreme Being company in Beijing) to carry out the detection of hemorheological indexes.
2.3.3 lipids detection patient takes a blood sample on an empty stomach, the zymetology method is measured T-CHOL (TC), triglyceride (TG), low density lipoprotein, LDL (LDL-C), high density lipoprotein (HDL-C) adopt RG-R801A automatic clinical chemistry analyzer (in Beijing diligent generation Supreme Being company) to detect.
2.3.4 glycolated hemoglobin: blood drawing on an empty stomach, the instant separation of serum of blood specimen, enzymic measuring reagent is provided by Beijing the last nine company.Only require metabolic syndrome group patient test.
2.3.5 blood glucose: blood drawing on an empty stomach, separation of serum, the oxidation enzymatic assays, reagent uses Shanghai Long March test kit.Only require metabolic syndrome group patient test.
The baseline value of all case treatment Pretesting nail fold microcirculation, blood fat, the every index of hemorheology, metabolic syndrome patient increases the baseline value of surveying blood glucose, glycolated hemoglobin index.Check nail fold microcirculation, blood fat, hemorheology, blood glucose, glycolated hemoglobin after treating 3 courses of treatment, carry out comparison before and after self treatment with baseline value before the treatment, to judge the clinical efficacy of " the cardiovascular and cerebrovascular vessel laser therapeutic apparatus of band target vessel irradiation positioner " that this utility model is made.
2.4 statistical method
The statistical procedures effluent south information computing center of the college of traditional Chinese medicine of clinical data provides, and data statistics is handled and adopted SPSS 10.0 for Windows statistical softwares.
Enumeration data is calculated total effective rate, and significance test adopts x
2Check is analyzed; Measurement data is calculated mean, standard deviation, and the t check is analyzed between significance test employing paired t-test or group.
2.5 criterion of therapeutical effect: " practical clinical microcirculation is learned " that " new Chinese medicine clinical research guideline ", PLA General Hospital professor Tian Niu who formulates with reference to Ministry of Health of the People's Republic of China edits, " the disease of tcm diagnosis criterion of therapeutical effect " of State Administration of Traditional Chinese Medicine's issue.
Produce effects: (1) clinical symptoms takes a turn for the better, and improves before the treatment to reach 2/3.(2) hemorheology: indexs such as whole blood viscosity, plasma viscosity, packed cell volume, erythrocyte aggregation index, Fibrinogen improve 〉=55% before the treatment.(3) nail fold microcirculation: the integrated value and the total mark value of pipe loop form, blood fluidised form, all forms of loop improve 〉=60% before the treatment.(4) lipids detection reaches following each person: total gallbladder alcohol (TC) descends 〉=20%, and triglyceride (TG) descends 〉=40%, high density lipoprotein (HDL-C) rising 〉=0.26mmol/L, and low density lipoprotein, LDL (LDL-C) descends 〉=20%.(5) blood glucose: fasting glucose descends 〉=30% before the treatment, or glycolated hemoglobin descends 〉=25% before the treatment.
Effectively: (1) clinical symptoms is partly improved, and alleviates before the treatment to reach 1/3.(2) hemorheology: indexs such as whole blood viscosity, plasma viscosity, packed cell volume, erythrocyte aggregation index, Fibrinogen improve before the treatment 〉=20% but<55%.(3) nail fold microcirculation: pipe loop form, blood fluidised form, loop week form integrated value and the total mark value improve before the treatment 〉=20% but<60%.(4) lipids detection reaches following each person: total gallbladder alcohol (TC) descend 〉=10% or<20%, triglyceride (TG) descend 〉=20% or<40%, high density lipoprotein (HDL-C) rising 〉=0.104mmol/L but<0.26mmol/L, low density lipoprotein, LDL (LDL-C) descend 〉=10% or<20%.(5) blood glucose: fasting glucose descend before the treatment 〉=10% but<30%, or glycolated hemoglobin descend before the treatment 〉=5% but<25%.
Invalid: after treating 3 courses of treatment continuously, subjective symptoms and blood fat do not have improvement, and hemorheology and nail fold microcirculation improve all less than 20% before the treatment, and fasting glucose descends<10% before the treatment, and glycolated hemoglobin descends<5% before the treatment.
3 therapeutic outcomes:
Table 3 the present invention treats the back clinical efficacy relatively
The sick kind | Example number (n) | Produce effects n (%) | Effective n (%) | Invalid n (%) | Total effective rate n (%) |
The cardiovascular diseases organizes cerebrovascular group peripheral angiopathy group metabolic syndrome group and amounts to | 37 33 15 35 120 | 22(59.46%) 18(54.55%) 8(53.33%) 19(54.29%) 67(55.83%) | 13(35.13%) 12(36.36%) 5(33.33%) 13(37.14%) 43(35.83%) | 2(5.41%) 3(9.09%) 2(13.33%) 3(8.57%) 10(8.33%) | 35(94.59%) 30(90.91%) 13(86.67%) 32(91.43%) 110(91.67%) |
The hemorheology measured value compared (x ± s n=95) before and after table 4 the present invention treated
Inspection item | Unit | Before the treatment | After the treatment | T value | The P value |
Whole blood contrast viscosity is low to be cut the whole blood contrast viscosity height and cuts plasma viscosity packed cell volume erythrocyte aggregation index Fibrinogen | MPa/s mPa/s mPa/s L/L - g/L | 19.24±0.59 5.30±0.88 1.75±0.47 0.49±1.21 6.43±0.77 4.07±0.91 | 17.11±0.68 4.31±0.74 1.68±0.55 0.42±1.17 4.69±0.62 3.88±0.74 | 6.18 2.41 2.94 3.73 5.46 3.55 | <0.01 <0.05 <0.05 <0.01 <0.01 <0.05 |
Blood fat compared (x ± s n=86) before and after table 5 the present invention treated
Project | Unit | Before the treatment | After the treatment | The t value | The P value |
T-CHOL (TC) triglyceride (TG) low-density lipoprotein (LDL-C) high-density lipoprotein (HDL-C) | mmol/L mmol/L mmol/L mmol/L | 8.08±1.23 2.21±0.44 4.25±0.38 1.42±0.20 | 5.42±1.14 1.66±0.62 3.36±0.27 1.74±0.31 | 3.65 2.24 2.86 1.53 | <0.01 <0.05 <0.01 <0.05 |
Blood glucose and glycolated hemoglobin compared (x ± s n=15) before and after table 6 the present invention treated
Project | Unit | Before the treatment | After the treatment | The t value | The P value |
Blood glucose (TC) glycolated hemoglobin (GSP) | mmol/L mmol/L | 7.72±1.55 2.93±1.04 | 6.13±1.42 2.36±0.95 | 4.17 2.86 | <0.05 <0.05 |
(x ± s n=120) compared in nail fold microcirculation before and after table 7 the present invention treated
Integrated value | Before the treatment | After the treatment |
A course of treatment | Two courses of treatment | Three courses of treatment |
Pipe loop form blood fluidised form loop week form total mark value | 1.78±0.35 2.62±0.42 1.47±0.29 5.87±0.53 | 1.55±0.28
* 1.43±0.36
* 1.44±0.18 4.42±0.44
* | 1.24±0.21
** 1.06±0.29
** 1.27±0.21
* 3.57±0.64
** | 1.12±0.19
** 0.69±0.23
** 1.01±0.17
* 2.82±0.64
** |
Annotate: own control is relatively before and after the treatment:
*P<0.05,
*P<0.01.
Table 8 the present invention treats the improvement situation of back clinical symptoms
Symptom | Routine number takes place | Incidence rate | Improve routine number | The improvement rate |
The dizzy palpitaition pectoralgia lassitude and weak soreness and weakness of waist and knees extremity numbness failure of memory slow in reacting of breathing hard uncomfortable in chest | 98 62 85 41 80 31 25 16 42 | 81.66% 51.66% 70.83% 34.17% 66.67% 25.83% 20.83% 13.33% 35.00% | 94 55 77 33 76 26 18 10 35 | 95.92% 88.71% 90.59% 80.49% 95.00% 83.87% 72.00% 62.50% 83.33% |
The clinical curative effect analysis of the cardiovascular and cerebrovascular vessel laser therapeutic apparatus of the band target vessel irradiation positioner that this utility model is made:
Clinical observation coronary heart disease, angina pectoris, myocardial infarction, rheumatic heart disease, pulmonary heart disease, cerebral infarction, cerebral thrombosis, cerebral arteriosclerosis, varicose veins of the lower extremity, thromboangiitis obliterans, diabetes, hyperlipidemia, the high blood viscosity that diseases such as hypertension cause, hyperlipemia, the cardiovascular and cerebrovascular vessel blood supply insufficiency, microcirculation disturbance and metabolic function syndrome patient be totally 120 examples, learn by statistics and handle, 120 routine patients adopt " the cardiovascular and cerebrovascular vessel laser therapeutic apparatus of the band target vessel irradiation positioner that this utility model is made " treatment, treatment back obvious effective rate 55.83%, effective percentage 35.83%, inefficiency 8.33%, clinical total effective rate is 91.67%, wherein the clinical total effective rate of cardiovascular disease group is 94.59%, the clinical total effective rate of cerebrovascular disease group is 90.91%, the clinical total effective rate of peripheral vascular disease group is 86.67%, and the clinical total effective rate of metabolic syndrome disease group is 91.43%.
The above results shows, the cardiovascular and cerebrovascular vessel laser therapeutic apparatus of the band target vessel irradiation positioner that this utility model is made is to cardiovascular and cerebrovascular disease, the dizziness that peripheral vascular disease and metabolic syndrome patient cause, cardiopalmus, sensation of oppression over the chest with shortness of breath, chest pain, tired unable, numb limbs and tense tendons, bradykinesia, clinical symptoms such as hypomnesis all have significant improvement, clinical symptoms improvement rate to dizziness is 95.92%, the improvement rate of sensation of oppression over the chest with shortness of breath is 90.59%, the improvement rate of chest pain is 80.49%, tired unable improvement rate is 95.00%, the improvement rate of cardiopalmus is 88.71%, the improvement rate of soreness of the waist and knees is 83.87%, unresponsive improvement rate is 72.00%, the improvement rate of hypomnesis is 83.33%, and the improvement rate of numb limbs and tense tendons is 62.50%.