CN2832050Y - Portable apparatus for detecting cardiovascular blood stream parameter - Google Patents

Portable apparatus for detecting cardiovascular blood stream parameter Download PDF

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Publication number
CN2832050Y
CN2832050Y CNU2005201139588U CN200520113958U CN2832050Y CN 2832050 Y CN2832050 Y CN 2832050Y CN U2005201139588 U CNU2005201139588 U CN U2005201139588U CN 200520113958 U CN200520113958 U CN 200520113958U CN 2832050 Y CN2832050 Y CN 2832050Y
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China
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pulse
pulse wave
chip microcomputer
circuit
flow parameter
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Expired - Fee Related
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CNU2005201139588U
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Chinese (zh)
Inventor
吴水才
杜旭
白燕萍
张松
李旭雯
杨益民
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Beijing University of Technology
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Beijing University of Technology
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Abstract

The utility model belongs to the technical field of a human body physiological parameter detection instrument. The existing eight-bit single-chip microcomputer has the defects of low calculation speed, poor data handling capacity, limited storage space and poor real-time performance, and a special signal acquisition card has high cost and poor compatibility. The utility model comprises a 16-bit single-chip microcomputer MSP430, a pulse signal amplification filter circuit, an A/D conversion device, an LCD display, a storage, a power supply circuit and a keyboard, wherein physiological parameters needed by a human body are firstly input by the keyboard, a pulse sensor is used for collecting pulse wave signals and the pulse wave signals are input in the pulse signal amplification filter circuit. The pulse wave signals then enter the single-chip microcomputer through the A/D conversion device, collected pulse waveforms are sent to the LCD display and are displayed and the collected pulse waveforms are stored in the storage. Subsequently, the stored data is analyzed and processed and the cardiovascular bloodstream parameters ar ecomputed. The instrument is supplied with power by a DC battery, and battery voltage is converted to needed voltage through a power supply circuit. The utility model is small and portable and has the functions that the real-time clear waveform display of pulse waves and the analysis and the processing of blood current.

Description

Portable cardiovascular flow parameter detector
Technical field
Portable cardiovascular flow parameter detector belongs to the human body physiological parameter detection and electronic medical instruments is developed technical field.
Background technology
Cardiovascular disease is the important diseases that current developed country mortality rate holds pride of place, and World Health Organization (WHO) has classified it as the No.1 killer of 21 century harm humans health, and cardiovascular flow parameter is the important evidence of cardiovascular disease diagnosis.The comprehensive condition of pulse wave reflection intravascular pressure, blood vessel wall tension force and the whole displacement of blood vessel is the most basic life parameters of human body.Learn according to clinical hemodynamics theory analysis, zoopery and clinical research: with the variation of physiological and pathological factors such as peripheral vascular resistance and blood vessel wall hardenability, the dynamic change of series of regular will appear in the waveform of human pulse ripple, pulse wave be detected processing can obtain human body cardiovascular hemodynamic mathematic(al) parameter.The pulse blood flow parameter detector that uses clinically 8 single-chip microcomputers or the PCs of adopting carry out the collection and the processing of pulse signal more in conjunction with the special signal capture card at present, the arithmetic speed of 8 single-chip microcomputers is low, data-handling capacity is not strong, and limited storage space, real-time are not strong; And special-purpose data acquisition card cost height, poor compatibility, the upgrading of its driver is comparatively difficult during as upgrading operation system.In addition, present existing cardiovascular function detector volume is bigger, costs an arm and a leg, and needs ac power supply, is not easy to carry.The doctor pays a home visit in the open air or will carry the blood flow parameter detector usually when going out to generally investigate, and just can't diagnose when not having alternating current power supply when neighbouring, delays patient's timely treatment.
Summary of the invention
In order to reach family and community health's purpose, need a kind of small portable, cardiovascular flow parameter detector with real-time clear pulse waveform demonstration and blood flow parameter analyzing and processing function, we have designed a kind of novel portable cardiovascular flow parameter detector for this reason, this instrument can noinvasive ground detects the information change of radial artery pulse wave, pulse wave signal is carried out analyzing and processing, finally calculate cardiovascular blood flow parameter.This instrument is stable, and is real-time, has low in energy consumptionly simultaneously, and volume is little, and is simple to operate, characteristics such as is convenient to carry, and is fit to family and community medicine health care use, and the early diagnosis of cardiovascular disease is had great importance.
The objective of the invention is to develop a kind of portable cardiovascular flow parameter detector, its technical scheme is seen Fig. 1, it is characterized in that, include 16 single-chip microcomputer MSP430, pulse signal amplification filtering circuit, A/D converter, LCD display, memorizer, power circuit, keyboard; When carrying out the cardiovascular flow parameter detection, at first detect needed human body physiological parameter (height, body weight, systolic pressure, diastolic pressure) by keyboard input blood flow parameter, the reuse pulse transducer is gathered pulse wave signal from the human body radial artery, input pulse signal amplification filtering circuit, send into single-chip microcomputer by A/D converter again, the pulse wave that collects is delivered on the LCD display and is shown, and is saved in the memorizer; Subsequently the pulse wave data of preserving are carried out analyzing and processing, calculate cardiovascular flow parameter, come the function status of diagnosis of cardiovascular as foundation with this according to existing formula; Instrument uses the dc-battery power supply, by power circuit cell voltage is converted to needed voltage;
Pulse signal amplification filtering circuit engineering scheme is seen Fig. 2, includes preamplifier, programmable amplifier, low pass filter, high pass filter, level conversion and amplitude limiter circuit; Preamplifier can amplify the small-signal from pulse transducer, in view of the individual difference of pulse wave signal is big, has designed the amplification of the automatic conditioning signal of programmable amplifier, prevents distorted signals; Disturb and external noise such as temperature drift for the power frequency that suppresses to introduce in the pulse signal gatherer process, designed low pass filter and high pass filter; Simultaneously, satisfy the input range of A/D converter, designed level conversion and amplitude limiter circuit in order to make analogue signal.
Can also the pulse wave data be sent on the PC by RS232 serial line interface or USB interface, be sent to hospital for the further analyzing and processing of doctor or by network remote.
This utility model has effectively overcome the deficiencies in the prior art, solved key technology problems, 16 single-chip microcomputer MSP430 of super low-power consumption are adopted in design, and select for use μ C/OS-II embedded real-time operating system as system kernel, make detector have advantages such as volume is little, low in energy consumption, stable and reliable operation.This detector cost is low, is easy to carry, and has improved the range of application of cardiovascular flow parameter detector greatly.
Description of drawings
Fig. 1: portable cardiovascular flow parameter detector structure chart;
Fig. 2: pulse signal amplification filtering circuit structure diagram;
Fig. 3: detector numerical portion circuit diagram;
Fig. 4: power circuit diagram;
Fig. 5: pulse signal amplification filtering circuit diagram.
The specific embodiment
Portable cardiovascular flow parameter detector of the present utility model with 16 single-chip microcomputer MSP430F449 of super low-power consumption as control core, the MSP430F449 single-chip microcomputer includes 12 A/D converters of one eight passage, therefore do not need to add the ADC chip, also contain two universal synchronous/asynchronous serial communication interface simultaneously, make Design of Interface Circuit simpler, integrated level is higher, and the volume of instrument significantly reduces, and has strengthened portability.
Traditional scm software is the AM/BAM mode, and the real-time of system is poor, and the difficulty and the complexity of software programming are bigger.Embedded real-time operating system (RTOS) provides the software frame of an opening and perfect multitask environment, and the design application software has not only been simplified the design of upper application software on RTOS, and has improved the reliability and the real-time of system.In order to overcome drawbacks such as the real-time that exists in traditional single task AM/BAM software design is poor, stability is low, the construction cycle is long, adopted the method for designing of embedded real-time multitask software.Select the embedded real-time operating system (RTOS) of μ C/OS-II real-time kernel for use,, μ C/OS-II is transplanted to the system hardware platform according to the characteristics of single-chip microcomputer and its C CompilerTools IAR Embedded Workbench as system.Simultaneously, under the kernel multiple task management mechanism of μ C/OS-II, the application demand of coupling system is divided the different task module, the design application layer software.
Portable cardiovascular flow parameter detector numerical portion circuit diagram of the present utility model as shown in Figure 3.Keyboard is interactive input equipment, can parameter be set to system by keyboard, sends control command etc.When the scanning digital input keyboard, each mouthful of P3.0-P3.3 of MSP430F449 single-chip microcomputer exported high level successively, if there is not button to press, the level state that each mouthful line reads in all is high; In case there is button to press, corresponding I/O mouth is a low level, detects once more after time-delay a period of time, if I/O is a low level still, defines button and presses, and the key value that identification is pressed is carried out operation accordingly.Among Fig. 3, S1 is a reset key, and S2 is a menu key, and S3 is for determining key, and S4 is a cancel key, and S4-S16 is a numeral keys, detects parameters such as needed height, body weight, systolic pressure, diastolic pressure by numeral keys's input blood flow parameter.U8 is RS232 serial interface chip MAX3232, and J6 is the serial line interface socket, can the pulse wave data be sent to PC by this serial communication interface.Because the signal level of MSP430 has only 3.3V,, the cmos voltage of MSP430 serial output is converted to the RS-232-C logic level of standard so select for use the new 3.3V logic level transition chip MAX3232 that releases of MAXIM company to finish level conversion.J5 is the LCD display interface socket, dot matrix lcd is except that showing the character, can also show various graphical informations, Chinese character etc., the design adopts the HY12864 dot matrix lcd, liquid crystal display HY12864 is one 128 * 64 dot matrix display module, EL is backlight, can display graphics and literal.J1 is that JTAG regulates interface socket, links to each other with PC by this socket, realizes the on-line debugging and the download of program.
U9 is a data storage, is serial FLASH chip AT45DB021, and FLASH type memorizer has the advantage that capacity is big, low in energy consumption, volume is little, and its price is than low many of SRAM.The RESET pin is a resetting pin in the AT45DB021 chip, and the WP pin is the write-protect foot, and the CS pin is the chip selection signal input pin, and SCK is the serial clock input pin, and SI is the serial data input pin, and SO is the serial data output pin.Chip AT45DB041 carries out corresponding operating according to the command word that master controller sends.After master controller drags down the CS signal end, provide correct chip operation word, just can data be write/read the word address or the main storage area page address of data designated relief area by string line.When read/write to the data buffer zone or during the last address of certain one page, internal pointer all will be returned the initial address of same data buffer zone or page or leaf, begin to read or write from initial address again, original data in these addresses will be refreshed.Transfer of data is carried out according to the process of elder generation's high-order back low level.For further expanding data storage capacity, increase memorizer U10 (chip 24C256) and be used for numerals such as store character.U11 is clock chip DS1302, for system provides clock signal.
For instrument is easy to carry, cardiovascular flow parameter detector employing+9V battery powered can be used in the open air.Because the device of MSP430 single-chip microcomputer and respective digital part adopts low level, so be designed to+power supply of 3.3V power supply, and the operational amplifier TL084 that simulation part such as amplifying circuit adopts in the detection system is ± the 5V power supply powers.Therefore, we need the power supply of handle+9V convert to+3.3V ,+5V and-5V, to supply with MSP430 single-chip microcomputer and simulation thereof, digital circuit part.Power circuit mainly adopts product MAX639, the MAX860 of MAXIM company and the product LP2985 of NS company as shown in Figure 4.MAX639 can be converted to the cell voltage of+9V+5V, uses for operational amplifier TL084.The input range of MAX639 is 4V to 11.5V, and device is exported+3.3V voltage automatically simultaneously, and perhaps the user can be adjusted into 1.3V to input voltage with output voltage by adjusting.MAX860 can with input voltage range+1.5V to the voltage equity of-5.5V be converted to corresponding negative voltage (promptly-5.5V arrives-1.5V), perhaps with input range for+2.5V to the voltage transformation of+5.5V be double output, and only use the function of its exportable negative pressure here, its input voltage is+5V that output voltage is-5V.LP2985 is output current 150mA, the voltage adjuster of fixing output, and it is applied to provide ultralow imbalance and noise voltage in the battery powered apparatus usually.The LP2985 maximum can be imported 16V voltage, and the scope of output voltage causes 5.0V at 2.8V.Quiescent current was less than 1 μ A when LP2985 closed, the accuracy rate height of output voltage, and the load of peak point current is big.The exemplary operation circuit of LP2985 as shown in Figure 4, input voltage is+9V that output voltage is+3.3V.
Pulse signal amplification filtering circuit as shown in Figure 5, it be by pre-amplification circuit (U2A, U2B, U2C), programmable amplifying circuit U4, low pass filter U3A, high pass filter U3B, level lifting circuit U3C and amplitude limiter circuit U3D form.Two 14 foot IC chip TL084 and a slice 16 foot IC chip CD4051 have been used in the circuit altogether.Have only tens millivolts from the voltage magnitude of the pulse wave signal of sensor acquisition, require the pulse wave amplifier should have tens times of amplifications usually to hundred times.Pre-amplification circuit adopts differential amplifier, can suppress null offset, increases input impedance, reduces common-mode signal and disturbs.The pressure pulse wave amplitude has the big characteristics of dynamic change scope because of individual different widely different, in order to satisfy different needs, has increased programmable amplifying circuit, realizes the automatic control of amplifier gain.The pressure pulse wave signal is vulnerable to electrical interference of 50Hz city and High-frequency Interference, so adopt a 40Hz low pass filter in the circuit, eliminates the 50Hz power frequency and disturbs, and suppresses other high-frequency noise.In addition, because the low-frequency disturbance such as artifact interference that vascular vibration and body kinematics cause, the high pass filter that has designed cut-off frequency in the circuit and be 0.1Hz suppresses low-frequency disturbance in order to weaken.Because the inside A/D module of MSP430 single-chip microcomputer can only be changed unipolar signal, so pulse wave signal need carry out level conversion, makes its waveform be in positive interval, therefore, need the design level lifting circuit to improve the voltage of simulation pulse wave signal.Simultaneously, do not exceed the reference voltage range of A/D module, also need to design the dynamic reference voltage that amplitude limiter circuit limits analogue signal in order to make pulse wave signal.
Utilize native system to detect 10 routine experimenters' cardio-vascular parameters, and contrast with the testing result of the TP-CBS II type cardiac function blood flow parameter detector of clinical extensive employing, the cardiovascular flow parameter testing result is more as shown in table 1.Both testing result basically identicals, and this instrument easy operating in blood flow parameter detects, favorable repeatability.
Each cardio-vascular parameters all is functions of form factor and heart rate, so these two parameters have directly reflected the accuracy of system.By table 1 as seen, the data basically identical of the TP-CBS II type system detection of the blood flow parameter of native system detection and clinical employing.As calculated, the average relative error of form factor is 1.9%; The average relative error of heart rate is 5.6%.The parameter that becomes when heart rate is may change with experimenter's emotion, the variation of the mental status, and fluctuation is normal to some extent in experimentation.
The cardiovascular flow parameter detector based on pulse wave information of our development can be gathered display pulse ripple information in real time, accurately automatically analyzes pulse wave signal, calculates blood flow parameter.Instrument adopts DC power supply, can carry, and is easy for operation, safe and reliable to operation, can satisfy the requirement of clinical use.
Table 1 cardiovascular flow parameter testing result relatively
Sequence number Using system Pulse frequency time/minute Stroke volume mL SI mL/m 2 Cardiac index L/min* m 2 Peripheral resistance PRU The K value Blood viscosity cP
1 2 3 4 5 6 7 TP M TP M TP M TP M TP M TP M TP M 69 70 63 66 70 63 86 79 76 78 82 87 72 75 62.15 58.49 67.76 63.31 48.48 55.32 45.05 48.57 84.07 81.43 74.49 77.25 46.65 45.80 44.97 42.33 38.77 36.23 29.31 33.45 33.90 36.55 52.14 50.51 42.96 44.56 32.87 32.28 3.10 2.96 2.45 2.39 2.05 2.11 2.91 2.89 3.98 3.94 3.52 3.88 2.36 2.42 1.11 1.30 1.14 1.31 1.56 1.62 1.16 1.29 0.79 0.94 0.84 0.89 1.42 1.49 0.35 0.36 0.36 0.37 0.42 0.42 0.39 0.39 0.34 0.35 0.34 0.33 0.42 0.42 4.05 4.10 4.16 4.19 4.90 4.79 4.45 4.43 3.96 3.96 3.84 3.77 4.84 4.75
8 9 10 TP M TP M TP M 89 88 91 96 75 66 71.43 79.55 70.40 67.45 70.69 93.72 43.52 48.48 42.90 41.11 39.73 52.69 3.89 4.21 3.90 3.95 3.97 3.48 0.82 0.88 0.95 0.94 1.00 0.98 0.36 0.35 0.36 0.36 0.37 0.35 4.15 3.98 4.16 4.14 4.33 4.02
Annotate: TP represents the testing result of TP-CBS, and M represents the testing result of the system that we develop.

Claims (2)

1, a kind of portable cardiovascular flow parameter detector is characterized in that, includes 16 single-chip microcomputer MSP430, pulse signal amplification filtering circuit, A/D converter, LCD display, memorizer, power circuit, keyboard;
Described pulse signal amplification filtering circuit includes preamplifier, programmable amplifier, low pass filter, high pass filter, level conversion and amplitude limiter circuit successively.
2, portable cardiovascular flow parameter detector according to claim 1 is characterized in that, can also above-mentioned pulse wave data be sent on the PC by RS232 serial line interface or USB interface.
CNU2005201139588U 2005-07-18 2005-07-18 Portable apparatus for detecting cardiovascular blood stream parameter Expired - Fee Related CN2832050Y (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102499650A (en) * 2011-11-29 2012-06-20 浙江大学 Method and device for power spectral parameter detection and analysis of pulse wave
CN107157467A (en) * 2017-06-13 2017-09-15 陈畅 A kind of photo-electric heart rate measuring instrument
CN108566541A (en) * 2018-06-27 2018-09-21 内蒙古鸿霖信息技术有限责任公司 A kind of wearable device based on data acquisition
CN109498041A (en) * 2019-01-15 2019-03-22 吉林大学 Driver road anger state identification method based on brain electricity and pulse information
CN110063719A (en) * 2019-05-27 2019-07-30 深圳六合六医疗器械有限公司 Sitting based reminding method and device
CN110897617A (en) * 2019-12-11 2020-03-24 北京工业大学 Measuring system of microvascular blood viscosity switching value based on pulse wave parameters
CN112842259A (en) * 2020-11-26 2021-05-28 山东宝盛鑫信息科技有限公司 Online dispersion method for specific crowd

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102499650A (en) * 2011-11-29 2012-06-20 浙江大学 Method and device for power spectral parameter detection and analysis of pulse wave
CN107157467A (en) * 2017-06-13 2017-09-15 陈畅 A kind of photo-electric heart rate measuring instrument
CN108566541A (en) * 2018-06-27 2018-09-21 内蒙古鸿霖信息技术有限责任公司 A kind of wearable device based on data acquisition
CN109498041A (en) * 2019-01-15 2019-03-22 吉林大学 Driver road anger state identification method based on brain electricity and pulse information
CN109498041B (en) * 2019-01-15 2021-04-16 吉林大学 Driver road rage state identification method based on electroencephalogram and pulse information
CN110063719A (en) * 2019-05-27 2019-07-30 深圳六合六医疗器械有限公司 Sitting based reminding method and device
CN110897617A (en) * 2019-12-11 2020-03-24 北京工业大学 Measuring system of microvascular blood viscosity switching value based on pulse wave parameters
CN110897617B (en) * 2019-12-11 2022-03-22 北京工业大学 Measuring system of microvascular blood viscosity switching value based on pulse wave parameters
CN112842259A (en) * 2020-11-26 2021-05-28 山东宝盛鑫信息科技有限公司 Online dispersion method for specific crowd

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