CN2728419Y - Target array device for vivi human eye retina cell imaging instrument - Google Patents

Target array device for vivi human eye retina cell imaging instrument Download PDF

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Publication number
CN2728419Y
CN2728419Y CN 200420060166 CN200420060166U CN2728419Y CN 2728419 Y CN2728419 Y CN 2728419Y CN 200420060166 CN200420060166 CN 200420060166 CN 200420060166 U CN200420060166 U CN 200420060166U CN 2728419 Y CN2728419 Y CN 2728419Y
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China
Prior art keywords
human eye
target
target array
imaging
eye retina
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Expired - Fee Related
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CN 200420060166
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Chinese (zh)
Inventor
凌宁
张雨东
饶学军
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Chengdu Micro Tech & Develop Co ltd
Institute of Optics and Electronics of CAS
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Chengdu Micro Tech & Develop Co ltd
Institute of Optics and Electronics of CAS
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Priority to CN 200420060166 priority Critical patent/CN2728419Y/en
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Abstract

A target array device for a vivi human eye retina cell imaging instrument is arranged on a human eye retina cell imaging instrument which is composed of a beacon light source, a beacon light alignment system, a caliber matching system, an optical adaptive system, which controls and guides a deformation mirror to carry out the regulation of aberration according to the aberration measured by a Hartmann wavefront sensor, a lighting and imaging system, etc. The utility model is provided with a target array device which is composed of a lighting LED array controlled by a computer, a target array reticle plate arranged on the lighting LED array, a target alignment object lens, a reflecting mirror and a spectroscope, and the target alignment object lens, the reflecting mirror and the spectroscope are arranged along a light path. The utility model can separate the aligned target with the beacon light, and is convenient for transverse scanning and imaging for different regions of retina as well as precise positioning of imaging regions.

Description

The target array apparatus that living human eye retina cell imager is used
This utility model belongs to medical checkout equipment, especially living human eye retina image-forming manufacturing field of equipment.
Background technology
Adaptive optical technique is just to begin the new optical technique that grows up the external seventies, it is by the dynamic wavefront error of real-time detection-control-correcting optical system, thereby thereby make optical system have the ability that automatic adaptation change of external conditions remains optimum Working, thereby improved imaging resolution greatly.Living human eye retina cell imager is a principle of utilizing adaptive optics, small tissues such as human eye optical fundus retina cell and blood capillary is carried out the Medical Instruments of high-resolution imaging.Living human eye is equivalent to an optical system, has various aberrations, adopts the adaptive optics alignment technique, then can correction time and the space on the living human eye aberration that all changes, thereby acquisition is near the high resolution optic cell image of diffraction limit.
Present patent application person has at first carried out human eye retina's high-resolution imaging adaptive optical technique research work at home since 1997, micro-strain mirror principle and manufacturing, human eye aberration Wavefront sensor principle and key technologies such as human eye aberration measurement and reconstruct have successively been broken through, having set up in the world in 2000, first cover has successfully carried out the adaptive optics of living human eye aberration and has proofreaied and correct based on practical small-sized human eye retina's high-resolution imaging adaptive optics experimental provision of whole integrated form micro-strain mirror.Living human eye retina cell imager adopts small-sized deformation reflection mirror as correcting element.In the imaging process, inject ophthalmic with a branch of semiconductor laser from pupil, form a hot spot on the optical fundus after human eye is assembled, penetrate from pupil behind fundus reflex, the wavefront error of this Shu Guang is exactly the aberration of human eye.Measure this aberration with small-sized Hartmann sensor, and guiding and controlled deformation reflecting mirror are proofreaied and correct to this aberration.After correction is finished,, after optical system is amplified, just can utilize imaging system to photograph high-resolution retina cell and blood capillary image with flash lamp illumination optical fundus retina.
During instrument work, at first carry out alignment function, according to the definite retina image-forming zone, optical fundus of operator's needs to observed human eye.Because this instrument is a kind of high-resolution, high enlargement ratio imaging system, during instrument work, at every turn can only be to the optical fundus retinal field domain imaging of 1 ° (1 ° is equivalent to zone, optical fundus hundreds of micron).For obtaining more comprehensive medical information by retina cell and blood capillary image, need carry out imaging to enough big retinal area, obviously, can't realize the imaging of retinal area seriality by any initiatively displacement of examinee.
The purpose of this utility model is a kind of novel living human eye retina cell imager of design, making it to have has purpose accurately to induce examinee's eyeball to do corresponding cooperation and reach to enlarge the retina image-forming surveyed area, be convenient to the different transverse areas of retina can be continuously the advantage of scanning imagery exactly.
Summary of the invention
The purpose of this utility model is to realize by following means.
Human eye retina's cell optical imagery instrument target array apparatus, be arranged on by beacon light source, beacon beam colimated light system, bore matching system, measure aberration control and guiding deformation reflection mirror according to Hartmann wave front sensor this aberration is carried out on human eye retina's cell optical imagery instrument that gauged optics Adaptable System, illumination and imaging system etc. form, have one by computer-controlled LED array for illumination and target array graticle placed on it and the target array apparatus formed along target collimator objective, reflecting mirror and the spectroscope of light path setting.
After adopting design as above, living human eye retina cell imager can under the autotelic guiding of target array apparatus, induce examinee's eyeball do corresponding cooperation and reach enlarge the imaging of retina image-forming surveyed area with to the different transverse area scanning imageries of retina.
Description of drawings
Fig. 1 is the index path that adopts living human eye retina cell imager of the present utility model.
Fig. 2 is the imaging optical path figure of this target array apparatus at human eye center concave point.
Fig. 3 is near the imaging optical path figure of this target array apparatus concave point of human eye center.
Fig. 4 is the front view of target array graticle.
The specific embodiment
Below in conjunction with accompanying drawing structure of the present utility model is described in further detail.
In Fig. 1,
1: observed human eye 2:0 spectroscope 3:1 spectroscope 4:2 spectroscope
5:1 reflecting mirror 6: beacon beam colimated light system 7:LD semiconductor laser
8: narrow band filter slice 9: lamp optical system 10: xenon lamp 11: Control Computer
12: high-voltage amplifier 13:1 bore matching system 14: deformation reflection mirror
15:2 bore matching system 16:2 reflecting mirror 17:3 spectroscope
18: Hartmann wave front sensor 19:3 reflecting mirror 20: image-forming objective lens
21: imaging CCD 22:4 reflecting mirror 23: target collimator objective 24 target arrays differentiation plate
25: LED array for illumination
As shown in Figure 1, during instrument work, at first carry out alignment function, required according to the operator, determine that retina image-forming zone, optical fundus to observed human eye is (with the human eye's visual axis angle theta, as Fig. 3), by corresponding lumination of light emitting diode in Control Computer (11) the control LED array for illumination (25), corresponding zone in the illumination target array differentiation plate (24) (the garden ring of a band cross), observed human eye is watched illumination target through No. 0 spectroscope (2), No. 4 reflecting mirrors (22) attentively by target collimator objective (23).After finishing aligning, carry out the optics adaptively correcting again, the beacon beam that is sent by LD semiconductor laser (7) collimates, expands bundle via beacon beam colimated light system (6), after No. 1 reflecting mirror (5) reflection, see through No. 2 spectroscopes (4) again, through No. 1 spectroscope (3) reflection, see through No. 0 spectroscope (2) and enter observed human eye (1); The beacon beam of observed human eye (1) optical fundus scattering sees through No. 0 spectroscope (2) and No. 1 spectroscope (3) passes through No. 1 bore matching system (13) again, reflect through deformation reflection mirror (14), by No. 2 bore matching systems (15), to No. 2 reflecting mirrors (16), reflected light reflects into Hartmann wave front sensor (18) through No. 3 spectroscopes (17), Hartmann's wavefront sensing (18) is delivered to Control Computer (11) with the error signal that records, be processed into control signal, after control signal send high-voltage amplifier (12) to amplify, be applied on the deformation reflection mirror (14), thus the wavefront error in the correction light path; Error correction finishes, Control Computer (11) is controlled to picture lighting source xenon lamp (10) work, the light that imaging lighting source xenon lamp (10) sends is through lamp optical system (9), narrow band pass filter (8), through No. 2 spectroscopes (4) and No. 1 spectroscope (3) reflection, see through No. 0 spectroscope (2) and advance human eye pupil (1), the required imaging region in illumination optical fundus, the light of fundus reflex is through No. 0 spectroscope (2), No. 1 spectroscope (3), see through No. 1 bore matching system (13), reflect through deformation reflection mirror (14) again, by No. 2 bore matching systems (15), through No. 2 reflecting mirrors (16), see through No. 3 spectroscopes (17) and No. 3 reflecting mirrors (19) and reflect into image-forming objective lens (20), image in CCD camera (21) target surface, thereby obtain human eye retina's picture.
Because human eye retina's cell optical imagery instrument is a kind of high-resolution, high enlargement ratio imaging system, during instrument work, at every turn can only be to the optical fundus retinal field domain imaging of a garden degree (the about hundreds of micron in zone, optical fundus).In order to enlarge retinal field domain imaging scope, in instrument, added target array graticle (24), as shown in Figures 2 and 3, separate with beacon beam so that aim at the mark, be convenient to retina zones of different scanning imagery.Also can accurately locate simultaneously (with the human eye's visual axis angle theta) imaging region.As shown in Figure 3, the application-specific target array apparatus is made up of target array graticle (24), LED array for illumination (25), target collimator objective (23), No. 4 reflecting mirrors (22) and No. 0 spectroscope (2), throw light on target array graticle (24) zone of required image space, make observed human eye fixation object, this moment, the retinal area of instrument imaging was corresponding therewith.
As shown in Figure 4, target array graticle is the surface plate that is provided with hollow hole, and for ease of discrimination, the middle part of hollow hole is provided with cross benchmark graticule.

Claims (2)

1, the target array apparatus that living human eye retina cell imager is used, be arranged on by the beacon light source, the beacon beam colimated light system, the bore matching system, measure aberration control and guide deformation reflection mirror that this aberration is carried out gauged ADAPTIVE OPTICS SYSTEMS according to Hartmann wave front sensor, on the living human eye retina cell imager that illumination and imaging system etc. are formed, it is characterized in that having one by computer-controlled LED array for illumination and target array graticle placed on it and the target collimator objective that is provided with along light path, the target array apparatus that reflecting mirror and spectroscope are formed.
2, the target array apparatus of using according to the described living human eye retina cell imager of claim 1 is characterized in that, described target array graticle is the surface plate that is provided with the hollow hole of respective numbers.
CN 200420060166 2004-07-09 2004-07-09 Target array device for vivi human eye retina cell imaging instrument Expired - Fee Related CN2728419Y (en)

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Application Number Priority Date Filing Date Title
CN 200420060166 CN2728419Y (en) 2004-07-09 2004-07-09 Target array device for vivi human eye retina cell imaging instrument

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Application Number Priority Date Filing Date Title
CN 200420060166 CN2728419Y (en) 2004-07-09 2004-07-09 Target array device for vivi human eye retina cell imaging instrument

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101738721B (en) * 2009-12-25 2011-12-14 中国科学院光电技术研究所 Adaptive optical imaging system with system error-free Hartmann wavefront sensor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101738721B (en) * 2009-12-25 2011-12-14 中国科学院光电技术研究所 Adaptive optical imaging system with system error-free Hartmann wavefront sensor

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