CN2643866Y - Quick-acting biological enclosing and hemostatic strip - Google Patents
Quick-acting biological enclosing and hemostatic strip Download PDFInfo
- Publication number
- CN2643866Y CN2643866Y CN 03247224 CN03247224U CN2643866Y CN 2643866 Y CN2643866 Y CN 2643866Y CN 03247224 CN03247224 CN 03247224 CN 03247224 U CN03247224 U CN 03247224U CN 2643866 Y CN2643866 Y CN 2643866Y
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- hemostasis
- thrombin
- pasted
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Abstract
The utility model discloses a quick biology seal hemostasis band, being compounded by various materials, which is characterized in that the hemostasis band consists of a four or three or two layer structure; and essentially, a sheet hemostasis band is formed by a Collagen layer, an absorbable mesh layer, a fibrinogen layer and a thrombin layer through a freeze drying technical processing, which is able to be directly pasted on the wound, performing a function of quick hemostasis and closing the damaged tissue. The utility model has advantages of easy operation and safe and reliable using, and moreover, promising no poisonous side effect and being completely absorbed by the human body.
Description
Technical field
This utility model relates to medical supplies, and especially a kind of quick bio sealing hemostasis is pasted.
Background technology
At present; general on the market common hemostasis is pasted; it is made of adhesive plaster, drug hemostasis film and external protection, and this common hemostasis is only pasted for small size wound and the less external wounds of amount of bleeding and usefulness does not possess the sealing hemostasis requirement of surgical hemostasis and defective tissue.For addressing the above problem, people develop and adopt Fibrinogen and thrombin is the fibrin sealant of primary raw material, both at home and abroad after deliberation decades, and produce in batches on a large scale.But this product is owing to exist to use loaded down with trivial detailsly, and time is long, and therefore shortcoming such as might make mistakes in the preparation is not suitable for the occasion use of first aid.And in surgical operation, hemorrhage is individual very common phenomena; The injured back of soldier afield all is to cause death because of hemostasis fast and effeciently and wound closure more than 70%.The various casualty accidents that taken place in the middle of daily life as traffic accident etc., have also proposed requirement to quick-acting haemostatic powder.
Summary of the invention
The purpose of this utility model be to provide a kind of easy and simple to handle, need not loaded down with trivial details preparation, safe and reliable, can play the quick bio sealing hemostasis of quick-acting haemostatic powder and sealing defective tissue and paste.
The purpose of this utility model is achieved by the following scheme: this hemostasis is pasted and is constituted by multiple material is compound, by collagen layer, absorbable woven mesh layer, Fibrinogen and XIII thrombin layer, the compound formation four synusia shape structures hemostasis of thrombin and adminicle layer pasted respectively.
Above-mentioned quick bio sealing hemostasis is pasted, and constitutes one deck composite bed and collagen layer and absorbable woven mesh layer by Fibrinogen and XIII thrombin layer and thrombin and two kinds of combinations of substances of adminicle layer and constitutes three-layer tablet shape structure hemostasis subsides jointly.
Above-mentioned quick bio sealing hemostasis is pasted, and constitutes one deck composite bed by Fibrinogen and XIII thrombin layer and thrombin and two kinds of combinations of substances of adminicle layer and constitutes two synusia shape structures hemostasis subsides jointly with collagen layer.
Above-mentioned quick bio sealing hemostasis is pasted, and said adminicle layer is by calcium ion, aprotinin, vitamin B
2, the composite bed formed of heparin antagonist constitutes.
Advantage of the present utility model is: the mechanism of action that this hemostasis is pasted is the final stage that simulate blood is solidified, Fibrinogen is under the effect of thrombin and calcium ion, form the fibrin net, again under the effect of XIII thrombin, become stable fibrin net, stick to effects such as playing hemostasis, sealing defective tissue on the wound.Have safe and reliable, easy to operate, human body is had no side effect, has the favorable tissue compatibility, be easy to by advantages such as body absorptions.
Description of drawings
Below in conjunction with accompanying drawing this utility model is illustrated.
Fig. 1 structural representation of the present utility model;
Fig. 2 is that of the present utility model another implemented illustration.
Fig. 3 is that of the present utility model another implemented illustration.
The specific embodiment
Embodiment one:
As shown in Figure 1: this hemostasis is pasted and is made of multiple material, comprises four-layer structure, and it constitutes laminated structure by collagen layer 1, absorbable woven mesh layer 2, Fibrinogen and XIII thrombin layer 3, thrombin and adminicle layer 4 respectively.Its processing technique is, with Fibrinogen composite bed 3 and thrombin composite bed 4 at low temperature 0-4 ℃ down and behind the organic solvent mixing, adopt the mode of laminated freezing, under-60 ℃, finish collagen solution freezing, cover the absorbable woven mesh layer 2 of one deck then in the above, go up Fibrinogen and XIII thrombin solution again, above-mentioned three kinds of materials are freezing fully under-60 ℃, on fibrinogen layer, go up thrombin and adminicle solution again, the laminated structure hemostasis is made in the lyophilization in-60 ℃ freeze dryer of four layers of material paste.
Embodiment two:
As shown in Figure 2, be another kind of embodiment of the present utility model, it comprises three-decker, constitutes laminated structure by collagen layer 1 absorbable woven mesh layer 2, Fibrinogen and XIII thrombin 3 and thrombin and adminicle layer 4 respectively.Its processing technique is that absorbable woven mesh layer 2 is covered on the cryodesiccated collagen layer 1 of process, with Fibrinogen composite bed 3 and thrombin composite bed 4 at low temperature 0-4 ℃ down and behind the organic solvent mixing, coating or spray or be dipped into and can absorb in the mesh grid 2 again be made the laminated structure hemostasis after will the organic solution volatilization and be pasted.
Embodiment three:
As shown in Figure 3: be another kind of embodiment of the present utility model, comprise that two-layer structure connects, constitute laminated structure by collagen protein 1, Fibrinogen and XIII thrombin 3 and thrombin and adminicle layer 4 respectively.Its processing technique is: the mix homogeneously in the low temperature 0-4 of q.s ℃ organic solvent with Fibrinogen composite bed 3 and thrombin composite bed 4, coating or spray or be dipped on cryodesiccated collagen layer 1 again treats that organic solvent volatilization back constitutes the lamellar hemostasis and pastes.
Claims (4)
1, a kind of quick bio sealing hemostasis is pasted, it is characterized in that: constitute by multiple material is compound, paste by the compound formation four synusia shape structures hemostasis of collagen layer (1), absorbable woven mesh layer (2), Fibrinogen and XIII thrombin layer (3), thrombin and adminicle layer (4) respectively.
2, quick bio according to claim 1 sealing hemostasis is pasted, and it is characterized in that: described hemostasis is pasted and is constituted one deck composite beds and collagen layer (1) and absorbable woven mesh layer (2) by the white former and XIII thrombin layer (3) of fiber and thrombin and (4) two kinds of combinations of substances of adminicle layer and constitute the subsides of stopping blooding of three-layer tablet shape structure jointly.
3, quick bio according to claim 2 sealing hemostasis is pasted, and it is characterized in that: described hemostasis is pasted and is constituted one deck composite beds and collagen layer (1) by Fibrinogen and XIII thrombin layer (3) and thrombin and (4) two kinds of combinations of substances of adminicle layer and constitute the subsides of stopping blooding of two synusia shape structures jointly.
4, quick bio sealing hemostasis according to claim 1 is pasted, and it is characterized in that: said auxiliary layer thing is by calcium ion, aprotinin, vitamin B
2, the heparin antagonist forms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03247224 CN2643866Y (en) | 2003-06-13 | 2003-06-13 | Quick-acting biological enclosing and hemostatic strip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03247224 CN2643866Y (en) | 2003-06-13 | 2003-06-13 | Quick-acting biological enclosing and hemostatic strip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2643866Y true CN2643866Y (en) | 2004-09-29 |
Family
ID=34292769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03247224 Expired - Lifetime CN2643866Y (en) | 2003-06-13 | 2003-06-13 | Quick-acting biological enclosing and hemostatic strip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2643866Y (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246974A (en) * | 2021-12-24 | 2022-03-29 | 中国人民解放军军事科学院军事医学研究院 | Preparation method of hemostatic patch |
-
2003
- 2003-06-13 CN CN 03247224 patent/CN2643866Y/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246974A (en) * | 2021-12-24 | 2022-03-29 | 中国人民解放军军事科学院军事医学研究院 | Preparation method of hemostatic patch |
| CN114246974B (en) * | 2021-12-24 | 2023-11-03 | 中国人民解放军军事科学院军事医学研究院 | Preparation method of hemostatic patch |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Effective date of abandoning: 20060419 |
|
| C25 | Abandonment of patent right or utility model to avoid double patenting |