CN2482076Y - Sample holding device for living body tissue infrared spectrum analysis - Google Patents
Sample holding device for living body tissue infrared spectrum analysis Download PDFInfo
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- CN2482076Y CN2482076Y CN 00238963 CN00238963U CN2482076Y CN 2482076 Y CN2482076 Y CN 2482076Y CN 00238963 CN00238963 CN 00238963 CN 00238963 U CN00238963 U CN 00238963U CN 2482076 Y CN2482076 Y CN 2482076Y
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- described sample
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Abstract
The utility model relates to a sample containing device of a living tissue infrared spectrum analysis. The sample containing device comprises a sample containing element and a supporting frame. The sample containing element comprises a sample containing concave groove, an infrared window plate, a concave groove cover plate, and a fixing device for fixing the concave groove cover plate in the sample containing groove. The sample containing device is used for directly measuring the infrared spectrum of a living tissue sample, avoiding the disadvantage of the traditional tablet pressing sample preparation technology. The utility model can be also used as the clinical diagnosis of a tumor tissue sample and a screening device of numbers of cancer tissue.
Description
The utility model relates to the sample apparatus for placing of a kind of active mass Infrared spectroscopy.Belong to the Infrared spectroscopy field.The sample analysis that can be used for tumor research and clinical diagnosis.
Tumour is the disease of serious harm health, diagnoses the oncotherapy scheme determination most important accurately.Traditional clinical tumor diagnosis is by the tissue pathological slice cytological observation, and its shortcoming is a trivial operations, and speed is slow, and subjective influence factor is big.Infrared spectrum is a kind of analytical technology of molecular level, and is accurate, quick, easy, automaticity is high.But the sample that makes with traditional infrared spectrum compressing tablet method for making sample easily absorbs water, easily contaminated, sample molecule and used chemical reagent may take place to interact etc., therefore, infrared spectroscopy is applied to tumor analysis and still has certain difficulty.
The purpose of this utility model provides a kind of without compressing tablet, can directly measure the sample apparatus for placing of human or animal's biological tissue Infrared spectroscopy.
The sample apparatus for placing of the utility model biological tissue Infrared spectroscopy shown in synoptic diagram, comprising:
Sample holds part (1) and bracing frame (2) thereof, it is a surface plate that described sample holds part (1), wherein have: sample holds groove (3), this groove be by dig out on the surface plate come or by be pressed into the groove that protrudes the plane on the surface plate, the bottom center of (3) has an infrared light to enter hole (4), infrared window oralia (5), groove cover plate (6), its middle part has an infrared light to portal (7) and groove cover plate (6) is fixed on sample and holds stationary installation (8) in the groove (3).Sample holds part (1) can be by stainless steel, aluminium alloy, aluminium, plastics or organic glass are made, its size and shape can be selected arbitrarily, comprise: square, rectangle, rhombus, triangle or circle etc., sample wherein holds groove (3) can be had a plurality of, comprise: one, three or five, lay respectively at the middle part of surface plate, three the in-line that is is arranged, five the cruciform that is is arranged, as Fig. 3 E, shown in the F, a plurality of samples hold groove (3) and are convenient to sample preparation and mensuration under identical conditions, eliminate some errors, to obtain the mean value of a tissue sample, or sample preparation a plurality of sample the time, measure and comparison, for example, normal, optimum, the comparison of the infrared spectrum of malignant tissue.Bracing frame (2) can be made by metal, plastics or timber, its height, and size can change arbitrarily as required.Infrared window oralia (5) is perhaps made by their combined material by germanium, calcium fluoride, silicon or barium fluoride.The size of recess cover (6) and shape can to hold the size and the shape of groove identical or different with sample, preferably identical person.
The characteristics and the excellent effect thereof of the sample apparatus for placing of the utility model Infrared spectroscopy:
(1) use the sample preparation of this device simple, convenient test, pollution-free;
(2) but the sample long preservation that makes, repeated test is unanimity as a result;
(3) cheap for manufacturing cost, safe in utilization;
(4) 70 many cases breast tissues, the analysis of 500 many cases cast-off cells, its result and pathology have been used for
The coincidence rate of checking is greater than 95%;
The quality height of the spectrogram that (5) records, favorable reproducibility.
Brief Description Of Drawings:
Fig. 1 is the schematic appearance of the sample apparatus for placing of the utility model Infrared spectroscopy.
Fig. 2
A is that sample holds the synoptic diagram that sample on part and the surface plate thereof holds groove, wherein can put into
Parts (5), (6) and hole (7) wherein do not draw;
B is the center line longitudinal profile synoptic diagram of above-mentioned A.
Fig. 3
C is that sample holds on part and the surface plate thereof and to protrude the synoptic diagram that its surperficial sample holds groove,
Wherein do not draw in the parts that can put into (5), (6) and hole (7) wherein;
D is the center line longitudinal profile synoptic diagram of above C.
Fig. 4
E is sample holds has three samples to hold groove on part and the surface plate thereof an arrangement mode synoptic diagram;
F is sample holds has five samples to hold groove on part and the surface plate thereof an arrangement mode synoptic diagram;
Fig. 5 is optimum, the pernicious breast that the sample apparatus for placing with the utility model Infrared spectroscopy records
The infrared spectrogram of glandular tissue; A is the infrared spectrogram of optimum people's breast tissue, and b is pernicious
The infrared spectrogram of people's breast tissue.
In order to be illustrated more clearly in the utility model, enumerate following examples, but it there is not any restriction to scope of the present utility model.
The sample apparatus for placing of this Infrared spectroscopy is made by stainless steel or organic glass, and just infrared window oralia is wherein made by calcium fluoride or silicon.Sample holds part for square, has three square samples that dig out on surface plate to hold groove on it, is in-line and arranges.The infrared window oralia is put into sample hold groove, place sample pressing plate that the center is porose thereon and press thereon, and with stationary installation it is fixed on sample and holds in the groove, the sample that so installs is held part insert on the bracing frame and can measure.But the as above sample long preservation that makes of method is through repeated test unanimity as a result.
Claims (5)
1, a kind of sample apparatus for placing of biological tissue Infrared spectroscopy, it is characterized in that, described sample apparatus for placing, comprise: sample holds part (1) and bracing frame (2) thereof, the height of this bracing frame, size energy random variation, it is a surface plate that described sample holds part (1), wherein have: sample holds groove (3), this groove be by dig out on the surface plate come or by being pressed into the groove that protrudes the plane on the surface plate, (3) bottom center has an infrared light to enter hole (4), infrared window oralia (5), groove cover plate (6), the center have an infrared light to portal (7) and groove cover plate (6) are fixed on sample and hold stationary installation (8) in the groove (3).
2, according to the described sample apparatus for placing of claim 1, it is characterized in that, described sample holds part (1) and is made by stainless steel, aluminium, aluminium alloy, plastics or organic glass, and wherein infrared window oralia (5) is perhaps made by their combined material by germanium, calcium fluoride, silicon or barium fluoride.
According to the described sample apparatus for placing of claim 1, it is characterized in that 3, that the shape that described sample holds part (1) is selected for use is square, rectangle, rhombus, triangle or circle.
According to the described sample apparatus for placing of claim 1, it is characterized in that 4, described sample holds the number of the groove (3) on the surface plate of part (1) and selects 1,3 or 5 for use, lay respectively at the surface plate middle part, be in-line or be cruciform;
According to the described sample apparatus for placing of claim 1, it is characterized in that 5, described sample holds the bracing frame (2) of part (1) and makes with metal, plastics or timber.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 00238963 CN2482076Y (en) | 2000-06-23 | 2000-06-23 | Sample holding device for living body tissue infrared spectrum analysis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 00238963 CN2482076Y (en) | 2000-06-23 | 2000-06-23 | Sample holding device for living body tissue infrared spectrum analysis |
Publications (1)
Publication Number | Publication Date |
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CN2482076Y true CN2482076Y (en) | 2002-03-13 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN 00238963 Expired - Fee Related CN2482076Y (en) | 2000-06-23 | 2000-06-23 | Sample holding device for living body tissue infrared spectrum analysis |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102506747A (en) * | 2011-10-08 | 2012-06-20 | 苏州赛琅泰克高技术陶瓷有限公司 | Ceramic substrate planar contour scanning system and method |
CN106289919A (en) * | 2016-10-31 | 2017-01-04 | 复旦大学 | A kind of Fourier transform infrared spectroscopy preparation of samples method for analyzing secondary protein structure in aqueous solution |
CN107144659A (en) * | 2017-05-26 | 2017-09-08 | 宁海德宝立新材料有限公司 | A kind of device and its application method for improving infrared detection signal |
CN107356548A (en) * | 2017-07-04 | 2017-11-17 | 贵州省分析测试研究院 | For determining the infrared absorption pool device of impurity content in titanium tetrachloride |
CN109406448A (en) * | 2018-10-25 | 2019-03-01 | 四川长虹电器股份有限公司 | Infrared spectrometer |
CN109580536A (en) * | 2018-12-17 | 2019-04-05 | 南京市江宁医院 | Sample arm based on Terahertz detection flesh tissue sample |
-
2000
- 2000-06-23 CN CN 00238963 patent/CN2482076Y/en not_active Expired - Fee Related
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102506747A (en) * | 2011-10-08 | 2012-06-20 | 苏州赛琅泰克高技术陶瓷有限公司 | Ceramic substrate planar contour scanning system and method |
CN106289919A (en) * | 2016-10-31 | 2017-01-04 | 复旦大学 | A kind of Fourier transform infrared spectroscopy preparation of samples method for analyzing secondary protein structure in aqueous solution |
CN107144659A (en) * | 2017-05-26 | 2017-09-08 | 宁海德宝立新材料有限公司 | A kind of device and its application method for improving infrared detection signal |
CN107144659B (en) * | 2017-05-26 | 2019-02-01 | 宁海德宝立新材料有限公司 | A kind of device and its application method improving infrared detection signal |
CN107356548A (en) * | 2017-07-04 | 2017-11-17 | 贵州省分析测试研究院 | For determining the infrared absorption pool device of impurity content in titanium tetrachloride |
CN109406448A (en) * | 2018-10-25 | 2019-03-01 | 四川长虹电器股份有限公司 | Infrared spectrometer |
CN109580536A (en) * | 2018-12-17 | 2019-04-05 | 南京市江宁医院 | Sample arm based on Terahertz detection flesh tissue sample |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C19 | Lapse of patent right due to non-payment of the annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |