CN2287722Y - Biological electric chemical sensor - Google Patents
Biological electric chemical sensor Download PDFInfo
- Publication number
- CN2287722Y CN2287722Y CN 97202252 CN97202252U CN2287722Y CN 2287722 Y CN2287722 Y CN 2287722Y CN 97202252 CN97202252 CN 97202252 CN 97202252 U CN97202252 U CN 97202252U CN 2287722 Y CN2287722 Y CN 2287722Y
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- electrode
- shell
- sensor
- dielectric film
- sensitive electrode
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Abstract
The utility model relates to a biological electric chemical sensor, which comprises a columnar type body and conducting wires which are connected with the columnar type body, wherein, the columnar type body comprises an insulating casing, a sensitive electrode, an insulation film, a porous plug, an auxiliary electrode and a reference electrode. The sensor can be used for acquiring electrochemical signals from living body tissue or in vitro tissue of human or animals, and consequently, the utility model is used for a clinical diagnosis for tumors.
Description
The utility model belongs to the electrochemical sensor field, in particular, relates to the bioelectrochemical sensor that can be used for the clinical tumor diagnosis.
Tumour has been that people are known to the harm of health, and judges that the character of tumour is most important for definite corresponding treatment scheme.But the clinical diagnosis of tumour will be proved conclusively by the pathological section result in the prior art, and its shortcoming is that complicated operation, speed are slow, can not accurately declare tumour character in the scene.
The purpose of this utility model provides a kind ofly can be directly obtains the bioelectrochemical sensor of electrochemical signals from human or animal's biological tissue or in vitro tissue.
Followingly bioelectrochemical sensor of the present utility model is described with reference to accompanying drawing.
Accompanying drawing 1 is the schematic appearance of bioelectrochemical sensor of the present utility model.
Accompanying drawing 3 is diagrammatic cross-sections of another embodiment of bioelectrochemical sensor of the present utility model.
Accompanying drawing 4 is diagrammatic cross-sections of another embodiment of bioelectrochemical sensor of the present utility model.
Accompanying drawing 5 is bioelectrochemical sensor using method synoptic diagram of the present utility model.
Referring to Fig. 1,2, bioelectrochemical sensor of the present utility model comprises a column 1 and coupled lead 2, described column 1 comprises that insulation crust 8 reaches the radial center parts sensitive electrode 3 of portion within it, these sensitive electrode 3 outer dielectric films 4 that are surrounded by, between dielectric film 4 and the shell 8 gap is arranged, this gap constitutes electrolyte inside and stores passage, porous plug 6 is equipped with on the top of described storage passage, described shell 8 is provided with electrolyte inside inlet 9 and described storage channel connection, in described storage passage, also be provided with contrast electrode 5 and the auxiliary electrode 7 of pressing close to dielectric film 4 and shell 8 respectively, the top ends 10 of described column 1 is a plane, described sensitive electrode 3, dielectric film 4, the top end face of porous plug 6 all is positioned on this plane 10, and described lead 2 contains three branch lines 11 of mutual insulating, 12,13 respectively with described sensitive electrode 3, contrast electrode 5, the tail end of auxiliary electrode 7 links to each other.The tail end of post cylinder 1 also can have the parts of a fixing cord 2.Wherein said sensitive electrode 3 can be made by graphite material by stone, and auxilliary rib electrode 7 can be made by any material that is selected from platinum, gold, the graphite, and contrast electrode is mercurous chloride electrode or silver a--silver chloride electrode.Electrolyte inside is phosphate buffer or physiological saline.Insulation crust 8 can be become by teflon, glass and other nonconductive material, every stopple 6 is made by organism or inorganics porosint such as porous ceramics, and electrolyte inside can be by wherein oozing out into column top end face 10.
Shown in Figure 3 is another embodiment of the utility model bioelectrochemical sensor, wherein sensitive electrode 3 is by a socket 3 ' " formation; the two should be the conduction connection when plugs and sockets cooperates is like this by changing this sensor of repeated use that plug can be easy with a removable plug 3.
Shown in Figure 4 is another embodiment of the utility model bioelectrochemical sensor, wherein different be with embodiment illustrated in fig. 2, store garden, the slope platform that the top fuses with shell, material is identical with shell (this garden platform is used for replacing the porous plug among Fig. 2) of passage at electrolyte inside, and the taper garden that the is shaped as platform of the termination of the dielectric film 4 outside the sensitive electrode 3, so that the dielectric film termination cooperates with garden, described slope platform wedgewise, electrolyte inside can lead to and can capillary action ooze top end face 10 to column 1 by the gap between dielectric film termination and garden, the slope platform.
Referring to Fig. 5, when live body that uses above-mentioned bioelectrochemical sensor test sick body organ or in vitro tissue, respectively with the connection sensitive electrode 3 of this sensor, contrast electrode 5, the branch line 11 of auxiliary electrode 7,12,13, working electrode with potentiostat 14, contrast electrode, auxiliary electrode interface 16,17,18 link to each other, the top end face 10 of this sensor is contacted fully with organ-tissue, at this moment the electrolyte inside in the electrolyte inside storage passage can ooze to the organ-tissue surface, by the electric potential scanning of potentiostat 14 outputs-0.2 to 1.2V (with respect to contrast electrode), respond by register system 15 record currents simultaneously.According to the difference of tumor tissues and normal structure current-responsive, the clinician can judge the character of tumour.
Use the utility model bioelectrochemical sensor all can test the live body or the in vitro tissue of sick body organ, safe in utilization, method is easy, and measurement result is reliable, can use this sensor to measure in surgical procedure, judges tumour character rapidly.
Claims (8)
1, a kind of bioelectrochemical sensor, comprise a column (1) and coupled lead (2), it is characterized in that described shape body (1) comprises that insulation crust (8) reaches the radial center parts sensitive electrode (3) of portion within it, the outer dielectric film (4) that is surrounded by of this sensitivity sense electrode (3), between dielectric film (4) and the shell (8) gap is arranged, this gap constitutes electrolyte inside and stores passage, porous plug (6) is equipped with on the top of described storage passage, described shell (8) is provided with electrolyte inside inlet (9) and described storage channel connection, in described storage passage, also be provided with contrast electrode (5) and the auxiliary electrode (7) of pressing close to dielectric film (4) and shell (8) respectively, the top ends of described column is a plane (10), described sensitive electrode (3), dielectric film (4), the top ends of porous plug (6) all is positioned on this plane (10), three branch lines (11) (12) (13) that described lead (2) contains mutual insulating respectively with described sensitive electrode (3), contrast electrode (5), the tail end of auxiliary electrode (7) links to each other.
2, sensor as claimed in claim 1 is characterized in that (3 ") constitute described sensitive electrode (3) by socket (3 '), removable plug.
3, sensor as claimed in claim 1, it is characterized in that described porous plug (6) is replaced by garden, slope that fuse with shell, that material is identical with shell platform, the taper garden that the is shaped as platform of sensitive electrode (3) external insulation film termination makes this dielectric film termination cooperate with garden, described slope platform wedgewise.
4,, it is characterized in that described sensitive electrode (3) made by graphite material as claim 1 or 2 or 3 described sensors.
5,, it is characterized in that described auxiliary electrode (7) made by any material that is selected from platinum, gold, the graphite as claim 1 or 2 or 3 described sensors.
6, do not require 1 or 2 or 3 described sensors as power, it is characterized in that described contrast electrode (5) is mercurous chloride electrode or silver a--silver chloride electrode.
7,, it is characterized in that described electrolyte inside is phosphate buffer or physiological saline as claim 1 or 2 or 3 described sensors.
8, sensor as claimed in claim 1 or 2 is characterized in that described shell (8) made by politef, and every stopple (6) is made by porous ceramics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97202252 CN2287722Y (en) | 1997-03-04 | 1997-03-04 | Biological electric chemical sensor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97202252 CN2287722Y (en) | 1997-03-04 | 1997-03-04 | Biological electric chemical sensor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2287722Y true CN2287722Y (en) | 1998-08-12 |
Family
ID=33923457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97202252 Expired - Fee Related CN2287722Y (en) | 1997-03-04 | 1997-03-04 | Biological electric chemical sensor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2287722Y (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100445737C (en) * | 2003-06-19 | 2008-12-24 | 爱科来株式会社 | Analysis implement with opening in insulation film |
| WO2015196554A1 (en) * | 2014-06-28 | 2015-12-30 | 苏州格林泰克科技有限公司 | Bioelectricity signal sensor |
| CN107271525A (en) * | 2017-07-31 | 2017-10-20 | 沈阳工业大学 | A kind of integrated form ampere detection sensor for micro-total analysis system chip |
| CN110865109A (en) * | 2019-12-25 | 2020-03-06 | 广州商辉仪业智能科技股份有限公司 | Reference electrode isolation adapter |
-
1997
- 1997-03-04 CN CN 97202252 patent/CN2287722Y/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100445737C (en) * | 2003-06-19 | 2008-12-24 | 爱科来株式会社 | Analysis implement with opening in insulation film |
| WO2015196554A1 (en) * | 2014-06-28 | 2015-12-30 | 苏州格林泰克科技有限公司 | Bioelectricity signal sensor |
| CN106999087A (en) * | 2014-06-28 | 2017-08-01 | 苏州格林泰克科技有限公司 | A kind of bioelectrical signals sensor |
| CN107271525A (en) * | 2017-07-31 | 2017-10-20 | 沈阳工业大学 | A kind of integrated form ampere detection sensor for micro-total analysis system chip |
| CN107271525B (en) * | 2017-07-31 | 2023-08-08 | 沈阳工业大学 | Integrated ampere detection sensor for micro total analysis system chip |
| CN110865109A (en) * | 2019-12-25 | 2020-03-06 | 广州商辉仪业智能科技股份有限公司 | Reference electrode isolation adapter |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |