CN2240724Y - Plasma separator for clinical blood analysis - Google Patents
Plasma separator for clinical blood analysis Download PDFInfo
- Publication number
- CN2240724Y CN2240724Y CN 95231906 CN95231906U CN2240724Y CN 2240724 Y CN2240724 Y CN 2240724Y CN 95231906 CN95231906 CN 95231906 CN 95231906 U CN95231906 U CN 95231906U CN 2240724 Y CN2240724 Y CN 2240724Y
- Authority
- CN
- China
- Prior art keywords
- blood
- filter
- utility
- model
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model relates to a plasma separator for clinical blood analysis, which belongs to the medical equipment. A disk shape filter chamber with an inlet and an outlet is provided with edge sealed multilayer filter membranes with the thickness of 1.2 mm macromolecule cellulose, silicate, cellulose acetate, etc. The front wall and the back wall of the filter chamber and among the filter membranes have no a front cavity chamber and a back cavity chamber. Compared with a traditional method, the utility model has the advantages of time saving and quick and simple use, and does not need the special equipment. The utility model can reduce secondary pollution, and has a strong practicability and an exact analysis test result.
Description
The utility model relates to a kind of medicine equipment, when specifically extracting blood of human body blood cell and blood plasma is implemented the utensil that separates.
The assay of blood constituent is the assay of serum composition.Contain blood cell and blood plasma in the blood, it is former only to differ from a cellulose between blood plasma and the serum.The blood cell composition accounts for 37-50% in the blood, must remove blood cell before the blood constituent assay.The tradition clinic laboratory analysis on blood constituents is that the operator is thrust human vein through 8-10 decimation in time second 4-6ml blood with needle tubing, injecting tube, fill in laboratory test report, the test tube numbering, send to the hydro-extractor centrifuging again, blood cell and blood plasma are separated, take out blood plasma with liquid flowing tube and inject trial jar, numbering is sent to assay.Its program is cumbersome, and is time-consuming, needs specialized equipment, is easy to deviation.
The purpose of this utility model provides that a kind of volume is little, and it is few to get blood flow volume, and velocity of separation is fast, and the blood plasma amount of obtaining is big, and low price can satisfy the clinic laboratory analysis on blood constituents needs, overcomes the Archon and the plasma separating unit of classic method drawback.
As everyone knows, absorb few blood flow volume in the short time, with minimum parting material area at the utmost point, separate the high blood of blood cell content, only effectively tackle blood cell, allow blood plasma pass through parting material, do not cause that again erythrocyte fragmentation produces haemoglobin, this is extremely difficult.
The utility model is to connect a thickness 5mm, the plasma separator of diameter 45mm between blood syringe needle and the needle tubing original getting.The operator inserts human vein with syringe needle, and when extracting with syringe, plasma separator is implemented to separate to blood cell in the blood and blood plasma at once.Operator's suction needle tubing be blood plasma rather than blood, the blood plasma of extraction directly can be sent to assay.Normal person's blood test is finished said procedure and is only needed 15-25 second.Blood constituent assay result and classic method are in full accord.
The utility model adopts multiple special high score superimposed by pore size from performance materials, realization is to the interception of gradient layer by layer of blood cell composition, be layer by layer when making the blood cell composition under low pressure by parting material, gradient, the interception of control arranged, the blood cell composition evenly distributes in parting material.Parting material has bigger absorption, and the interception capacity is effectively to the big blood separation of blood cell content, otherwise the blood cell that accounts for blood volume nearly 50% is effectively tackled, and evenly distributes.
Technical essential of the present utility model is: have multilayer filter membranes such as high molecular cellulose that edge sealing and thickness are 1.2mm, silicate, cellulose acetate are housed in the dish type filter chamber of import and export, be provided with front chamber and rear chamber between the antetheca in the filter chamber and rear wall and filter membrane.Filter membrane in the dish-type filter chamber is 4 layers, and thickness is that the high molecular cellulose thickness of 0.5mm respectively is two layer silicates of 0.3mm successively, and thickness is the cellulose acetate of 0.1mm; The unconcerned aperture of high molecular cellulose filter is 40-50 μ m.The aperture of two layer silicate filter membranes is respectively 10-20 μ m and 1-5 μ m, and the thickness of cellulose acetate filter membrane is 0.2-0.8 μ m.
The utility model plasma separator is developed at clinic laboratory analysis on blood constituents, its volume is little, in light weight, low price, be used for clinical blood testing, compare the school with classic method, save time, fast, simply, do not need specialized equipment, can reduce secondary pollution, practical, analyzing and testing result is accurate.The required serum isolation technics of the complete alternative traditional clinical blood analyzing detecting method of plasma separator of the present utility model, the blood separation that becomes a new generation is extracted serum and is used for the practical technique that clinical blood becomes assay.
Accompanying drawing is the structural representation that the utility model links to each other with syringe, syringe needle etc.
1 is syringe among the figure, and 2 are outlet, and 3 is the separation vessel filter chamber, and 4 is filter membrane, and 5 is chamber, and 6 are import, and 7 is syringe needle, and 8 is human body.
The aperture control and the Gradient distribution of parting material are very crucial, and it is the control core that realizes tackling layer by layer, evenly distributes.The control in parting material aperture is the filling of adopting inert substance, fixedly realizes, it can make parting material be adjusted, control from microcosmic, the aperture of parting material is controlled at best uniform state, thus realize to blood cell effectively layer by layer, gradient, interception and evenly distribute.
The parting material that the utility model is selected for use is that plain superimposed the making of various organic celluloses, inorganic fibre of special preparation has in-depth filtration performance tablet, again according to layer by layer, gradient interception demand, inject filling material, make aperture appropriateness, the uniform various parting materials in aperture.The utility model can realize efficiently tackling the purpose of blood cell with the filtering material combination effectively and reasonably that various special preparations go out, and efficient can reach 99%-100%.
The utility model is done the terminal parting material with cellulose acetate (CA) microporous barrier, and the CA membrane aperture is controlled at 0.2-0.8 μ m, makes with curtain coating, evaporation method.Its performance requirement good hydrophilic property, the aperture is even, and percentage of open area is big, guarantees to have the final interception quality of fabulous blood plasma by speed and remaining blood cell.The utility model is packed above-mentioned various filter materials in the dish type filter chamber, and implements sealing at the edge, and import and export are connected with syringe needle, syringe, forms a complete clinic laboratory analysis on blood constituents and a plasma separator of can be used for.The dish type filter chamber import and export of joining with syringe needle and syringe place its antetheca sidepiece and rear wall middle part to be advisable; Ante-chamber and back cavity spacing that antetheca and rear wall and filter membrane constitute are 1mm.
The utility model has the colloid composition for blood cell content in the solution blood is big, easily adheres to the parting material surface, forms filter cake, stops up liquid flow path, has adopted:
1. the separation method that combines is filtered in in-depth filtration and screening;
2. the filter material in the different apertures of multilayer is superimposed, layer by layer, the gradient interception, the blood cell composition is evenly distributed in parting material.
3. with completion method the inert material is immersed in the parting material, adjust the aperture of filter material, improve the separating effect of filter material;
At the analysis of blood clinical assay fast, get that blood flow volume is few, volume is little, need serum amount few, use characteristics such as simple, the utility model has adopted special manufacturing process, be developed into plasma separator and be used for the clinical blood assay, to substitute conventional art, this is innovation of the present utility model.
The thick 5mm of plasma separator, diameter 45mm disk-like structure is equipped with 4 kinds of filter materials and is superimposed gross thickness 1.2mm in the cavity.To be that macromolecular fibre is special form the ground floor filter material, with completion method control aperture 40-50 μ m; Second layer filter material is made with special silicate material, and the aperture is controlled at 10-20 μ m; The 3rd metafiltration material is made with special silicate material, and the aperture is controlled at 1-5 μ m; The 4th metafiltration material is made with CA, and the aperture is controlled at 0.2-0.8 μ m.
With plasma separator inlet needle insertion human vein, blood promptly flows out and enters the device chamber, inserts the filter outlet with needle tubing and extracts, and 15-25 can extract 0.5ml blood plasma in second, and through comparing with classic method, every index is in full accord, please see following contrast table.
Lab work tradition centrifuge method plasma separator method
LDH 224 226
ALT 78 77
AST 104 103
ALT 64 62
AKD 70 68
Serum potassium 3.84 3.84
Sodium 134 129
Chlorine 113 112
Claims (2)
1. plasma separator that is used for clinic laboratory analysis on blood constituents, it is characterized in that being equipped with in having the dish type filter chamber (3) of import and export edge sealing and thickness is high molecular cellulose, silicate, the cellulose acetate multilayer filter membrane (4) of 1.2mm, is provided with forward and backward chamber (5) between the antetheca in the filter chamber and rear wall and filter membrane.
2. according to the described plasma separator of claim 1, it is characterized in that the filter membrane (4) in the dish type filter chamber (5) is 4 layers, thickness is that high molecular cellulose, the thickness of 0.5mm respectively is two layer silicates of 0.3mm successively, thickness is the cellulose acetate of 0.1mm; The aperture of high molecular cellulose filter membrane is 40-50 μ m, and the aperture of two layer silicate filter membranes is respectively 10-20 μ m and 1-5 μ m, and the thickness of cellulose acetate filter membrane is 0.2-0.8 μ m.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95231906 CN2240724Y (en) | 1995-08-09 | 1995-08-09 | Plasma separator for clinical blood analysis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95231906 CN2240724Y (en) | 1995-08-09 | 1995-08-09 | Plasma separator for clinical blood analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2240724Y true CN2240724Y (en) | 1996-11-20 |
Family
ID=33876403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 95231906 Expired - Fee Related CN2240724Y (en) | 1995-08-09 | 1995-08-09 | Plasma separator for clinical blood analysis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2240724Y (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102527117A (en) * | 2010-12-24 | 2012-07-04 | 成功大学 | Blood separation method |
| CN103528876A (en) * | 2013-10-29 | 2014-01-22 | 江苏德威兰医疗器械有限公司 | Serum rapid separator |
| CN109529444A (en) * | 2018-12-17 | 2019-03-29 | 刘向晖 | The filtering technique and filter of haemocyte in a kind of removal blood sample |
| WO2020220157A1 (en) * | 2019-04-27 | 2020-11-05 | 南京岚煜生物科技有限公司 | Whole blood filtering method and filter membrane structure for whole blood filtering |
| WO2021015808A1 (en) * | 2019-07-19 | 2021-01-28 | Siemens Healthcare Diagnostics Inc. | Tangent flow hemolysis detection blood testing device |
-
1995
- 1995-08-09 CN CN 95231906 patent/CN2240724Y/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102527117A (en) * | 2010-12-24 | 2012-07-04 | 成功大学 | Blood separation method |
| CN103528876A (en) * | 2013-10-29 | 2014-01-22 | 江苏德威兰医疗器械有限公司 | Serum rapid separator |
| CN109529444A (en) * | 2018-12-17 | 2019-03-29 | 刘向晖 | The filtering technique and filter of haemocyte in a kind of removal blood sample |
| WO2020220157A1 (en) * | 2019-04-27 | 2020-11-05 | 南京岚煜生物科技有限公司 | Whole blood filtering method and filter membrane structure for whole blood filtering |
| WO2021015808A1 (en) * | 2019-07-19 | 2021-01-28 | Siemens Healthcare Diagnostics Inc. | Tangent flow hemolysis detection blood testing device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69732928T2 (en) | Blood filter unit | |
| US6659975B2 (en) | Plasma collecting device | |
| DE69623180T2 (en) | Plasma separation filter, plasma separation method using this filter and plasma separation device | |
| FI116366B (en) | A method for treating a biological fluid | |
| DE69005354T4 (en) | Device and method for reducing the leukocyte content of blood and blood components. | |
| EP3808434B1 (en) | Whole blood filtering method and filter membrane structure for whole blood filtering | |
| NO309309B1 (en) | Device for separating leukocytes from platelet concentrate | |
| CA2074592A1 (en) | Filter and method for obtaining platelets | |
| CN108136395B (en) | Depth filtration device for separating sample phases | |
| DE10046173C2 (en) | Device and method for separating undissolved components from biological liquids | |
| US6220453B1 (en) | Blood filter unit | |
| US20040060859A1 (en) | Continuous blood filtration apparatus | |
| DE69904971T2 (en) | Method for separating serum from whole blood | |
| CN2240724Y (en) | Plasma separator for clinical blood analysis | |
| CN108008032A (en) | A kind of drop micro-fluidic chip and detection method for the detection of diabetes high sensitivity | |
| JPH06206008A (en) | Method for executing density gradient centrifugal separation and insert for making layer used for it | |
| CN1065738C (en) | Blood plasma separator for clinic laboratory analysis on blood constituents | |
| CN218475122U (en) | Blood filtering device | |
| JP2021177827A (en) | Syringe system, method for preparing platelet-rich plasma | |
| JPS6011166A (en) | Sampling method of blood plasma for clinical inspection | |
| WO2019136086A1 (en) | Device for blood collection | |
| Solomon | Membrane separations: technological principles and issues | |
| JP2000074908A (en) | Hemofilter | |
| CN111939599B (en) | Method and device for preparing platelet-rich plasma | |
| CN215328073U (en) | Integrated vacuum collection tube for separating peripheral blood mononuclear cells |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |