CN221580401U

CN221580401U - Mixing device for preparing clofarabine

Info

Publication number: CN221580401U
Application number: CN202323200121.4U
Authority: CN
Inventors: 冯成亮; 张爱青
Original assignee: Anhui Chenglian Medicine Technology Co ltd
Current assignee: Anhui Chenglian Medicine Technology Co ltd
Priority date: 2023-11-27
Filing date: 2023-11-27
Publication date: 2024-08-23
Anticipated expiration: 2033-11-27

Abstract

The utility model discloses a mixing device for preparing clofarabine, which comprises two supporting frames and a mixing barrel, wherein a feed inlet is connected above one side of the mixing barrel in a penetrating way, a discharge outlet is connected at the bottom of the mixing barrel in a penetrating way, and the mixing device further comprises: the upper parts of two sides of the mixing barrel are symmetrically provided with column blocks, one sides of the two column blocks are respectively and fixedly connected with two supporting frames through bearings in a rotating way, rotating assemblies are symmetrically arranged below the two sides of the mixing barrel, and the mixing barrel is internally and top provided with a mixing assembly, wherein the rotating assemblies comprise a shell fixedly arranged on one side of the top of the supporting frames, and one side of the upper part of the inner part of the shell is rotatably connected with a bidirectional worm through bearings; the mixing barrel can swing reciprocally without manpower in the mixing process, so that materials inside the mixing barrel are fully mixed and stirred, and the working efficiency and the practicability are improved.

Description

Mixing device for preparing clofarabine

Technical Field

The utility model relates to the technical field of preparation of clofarabine, in particular to a mixing device for preparing clofarabine.

Background

Clofarabine (Cephalosporin) is a beta-lactam antibiotic and the mixing process is mainly to uniformly distribute and mix different raw materials.

The publication No. CN213611097U discloses a stirring device for chemical synthesis of medicines, and the patent stirs medicines in a stirring barrel through a stirring device arranged on a rotating shaft so that a plurality of medicines can be fully mixed; the rotating shaft drives the gear to rotate, the gear is meshed with a sector gear arranged on one side of the sector cradle, the stirring barrel is connected with the supporting frame through a fixing pin, and the gear rotates to drive the sector cradle and the stirring barrel to swing; the stirring device can not pile up at stirring dead angle when stirring, makes the more abundant of medicine stirring, and the medicine in the agitator can not deposit, has the getting rid of the medicine of being convenient for, but this patent still has following problem in the in-service use:

The rotating shaft is used for driving the gear to rotate, the gear is meshed with a sector gear arranged on one side of the sector cradle, the stirring barrel is connected with the supporting frame through a fixing pin, and the gear rotates to drive the sector cradle and the stirring barrel to swing; the stirring device can not pile up at stirring dead angle in the medicine when stirring, makes the medicine stirring more abundant, but mainly rotates the axis of rotation constantly through the manpower when in-service use and makes the agitator swing, and is comparatively laborious at wobbling in-process, has promoted staff's work burden, and long-time use after the staff feel tired can reduce compounding efficiency.

A mixer for preparing clofarabine is provided to solve the above-mentioned problems.

Disclosure of utility model

The utility model aims to provide a mixing device for preparing clofarabine, which is used for solving the problems that in the prior art, a rotating shaft drives a gear to rotate, the gear is meshed with a sector gear arranged on one side of a sector cradle, a stirring barrel is connected with a supporting frame through a fixing pin, and the gear rotates to drive the sector cradle and the stirring barrel to swing; the stirring device can not pile up at stirring dead angle in the medicine when stirring, makes the medicine stirring more abundant, but mainly rotates the axis of rotation constantly through the manpower when in-service use and makes the agitator swing, and is comparatively laborious at wobbling in-process, has promoted staff's work burden, and long-time use after the staff feel tired can reduce the problem of compounding efficiency.

In order to achieve the above purpose, the present utility model provides the following technical solutions: a mixing device for preparing clofarabine comprises two supporting frames and a mixing barrel;

a feeding port is connected above one side of the mixing barrel in a penetrating way, and a discharging port is connected at the bottom of the mixing barrel in a penetrating way;

Further comprises:

The upper parts of two sides of the mixing barrel are symmetrically provided with column blocks, one sides of the two column blocks are respectively connected with fixing frames through bearings in a rotating way, the two fixing frames are respectively and fixedly connected with two supporting frames, rotating assemblies are symmetrically arranged below the two sides of the mixing barrel, and mixing assemblies are arranged in the mixing barrel and at the top of the mixing barrel;

The rotating assembly comprises a shell fixedly arranged at one side of the top of the supporting frame, a bidirectional worm is rotatably connected to one side above the inside of the shell through a bearing, one end of the bidirectional worm penetrates through the shell and is fixedly provided with a first motor, and the first motor is fixedly connected with the shell;

Wherein, the inside both sides of casing are connected with the dwang through bearing symmetry rotation, and the outside one side of two dwang is all fixed mounting has the worm wheel to two worm wheels all are connected with two-way worm meshing, and the outside opposite side of two dwang is all fixed mounting has the half gear moreover.

Preferably, the inside of casing is located and is connected with the axis of rotation through the bearing rotation between two dwang, and outside one side fixed mounting of axis of rotation has the rotation gear to the rotation gear is connected with two half gear engagement, and two dwang all are connected with the locating plate through the bearing rotation with the outside of axis of rotation moreover, locating plate and casing fixed connection.

Preferably, a sector gear is arranged above the shell and is meshed with the rotating gear, the top of the sector gear is fixedly provided with a mounting plate, the top of the mounting plate is fixedly provided with a fixing rod, the inside of the fixing rod is provided with a sliding groove, the inside of the sliding groove is slidably connected with a sliding rod, and the sliding rod is fixedly connected with the column block.

Preferably, the mixing barrel is located two groups of fixed blocks symmetrically arranged on two sides of the mounting plate, two groups of sliding rods are fixedly arranged between the two groups of fixed blocks respectively, a sliding sleeve is sleeved outside the sliding rods, and the sliding sleeve is fixedly connected with the mounting plate.

Preferably, the mixing assembly comprises a mounting frame fixedly mounted at the top of the mixing barrel, a second motor is fixedly mounted in the mounting frame, a stirring shaft is fixedly mounted at the output end of the second motor, the stirring shaft is rotationally connected with the mixing barrel through a bearing, the bottom of the stirring shaft is rotationally connected with a mounting rod through the bearing, and the mounting rod is fixedly connected with the mixing barrel.

Preferably, a plurality of first stirring blades are symmetrically arranged on the outer side of the stirring shaft, the top of the mounting rod is symmetrically and rotationally connected with the movable rod through a bearing, the two movable rods are rotationally connected with the mixing barrel through bearings, the tops of the two movable rods penetrate through the mixing barrel and are fixedly provided with second belt wheels, a plurality of second stirring blades are fixedly arranged on one side of the outer side of the two movable rods, a first belt wheel is fixedly arranged on the upper side of the outer side of the stirring shaft, and the first belt wheel is rotationally connected with the second belt wheel through a belt.

Preferably, two groups of slide bars are respectively sleeved with a reset spring at one side of the outer part, one end of each reset spring is fixedly connected with the sliding sleeve, and the other end of each reset spring is fixedly connected with one side of the fixing block.

Compared with the prior art, the utility model has the beneficial effects that: this compounding device is used in clofarabine preparation has set up rotating assembly at the bilateral symmetry of compounding bucket for need not also can reciprocal swing compounding bucket with the help of the manpower at the compounding in-process, can make the inside material of compounding bucket carry out intensive mixing stirring, promoted work efficiency and practicality, its concrete content is as follows:

1. When preparing the mixing materials, pouring the raw materials into the mixing barrel from a feed inlet, starting a first motor to drive a bidirectional worm to rotate in a shell, driving two rotating rods to rotate in the shell through meshing of the bidirectional worm and a worm wheel, driving two half gears to reversely rotate simultaneously, meshing the half gears on one side to drive the rotating gears to rotate after rotating, meshing teeth on the half gears on one side with the rotating gears to enable the rotating gears to reversely rotate, further enabling the rotating gears to reciprocally rotate, driving the sector gears to reciprocally rotate through meshing with the sector gears after reciprocally rotating, driving sliding rods to rotate through a mounting plate and fixing rods, driving the sliding rods to be fixedly connected with the column blocks to enable the column blocks to rotate on a fixing frame, enabling the mixing barrel to reciprocally swing, enabling the sliding sleeve to slide on the sliding rod while swinging the sector gears, enabling the sliding rod to slide inside the sliding groove, enabling the reset spring to restore the rotating gears to reciprocally rotate, enabling the sector gears to be tightly attached to the mixing barrel, and enabling the mixing barrel to rotate in a practical mode by means of full rotation of the mixing barrel;

2. The inside and the top at the compounding bucket have set up the compounding subassembly, can start the second motor at first and drive the (mixing) shaft and rotate on the installation pole when mixing the material, the (mixing) shaft can drive first band pulley rotation in the pivoted, first band pulley can drive the second band pulley through the belt and rotate for two movable levers rotate, make two sets of first stirring vane and two sets of second stirring vane rotate, and first stirring vane and the crisscross setting of second stirring vane, can be further mix the material through the compounding subassembly, promote the mixing effect of material, make the compounding more even quick.

Drawings

FIG. 1 is a schematic diagram of the front structure of the present utility model;

FIG. 2 is a schematic top view of the interior of the housing of the present utility model;

FIG. 3 is an enlarged schematic view of the area A in FIG. 1 according to the present utility model;

FIG. 4 is an enlarged view of the area B of FIG. 1 according to the present utility model;

FIG. 5 is a schematic diagram of a cross-sectional front view of a mixing bowl according to the present utility model.

In the figure: 1. a support frame; 101. a mixing barrel; 102. a feed inlet; 103. a discharge port; 104. a column block; 105. a fixing frame; 2. a rotating assembly; 201. a housing; 202. a bidirectional worm; 203. a first motor; 204. a rotating lever; 205. a worm wheel; 206. a half gear; 207. a rotating shaft; 208. rotating the gear; 209. a positioning plate; 210. a sector gear; 211. a mounting plate; 212. a fixed rod; 2121. a sliding groove; 213. a slide bar; 214. a fixed block; 215. a slide bar; 216. a sliding sleeve; 217. a return spring; 3. a mixing component; 301. a mounting frame; 302. a second motor; 303. a stirring shaft; 304. a mounting rod; 305. a first stirring blade; 306. a movable rod; 307. a second stirring blade; 308. a first pulley; 309. and a second pulley.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

Referring to fig. 1-5, the present utility model provides the following technical solutions: the utility model provides a clofarabine preparation is with compounding device, includes two support frames 1 and compounding bucket 101, and one side top through-connection of compounding bucket 101 has feed inlet 102, and the bottom through-connection of compounding bucket 101 has discharge gate 103, still includes: the pole piece 104 is installed to the both sides top symmetry of compounding jar 101, and one side of two pole pieces 104 all is connected with mount 105 through the bearing rotation, and two mount 105 respectively with two support frames 1 fixed connection, and the both sides below symmetry of compounding jar 101 is provided with rotating assembly 2 moreover, and the inside and the top of compounding jar 101 are provided with compounding subassembly 3, wherein rotating assembly 2 is including the casing 201 of fixed mounting in support frame 1 top one side, and inside top one side of casing 201 is connected with two-way worm 202 through the bearing rotation, and the one end of two-way worm 202 passes casing 201 and fixed mounting have first motor 203, and first motor 203 and casing 201 fixed connection, wherein, the inside both sides of casing 201 are connected with dwang 204 through the bearing symmetry rotation, and the outside one side of two dwang 204 is all fixed mounting 205, and two worm wheel 205 are all connected with two-way worm 202 meshing, and the outside of two dwang 204 is all fixed mounting has half gear 206, make through rotating assembly 2 can swing compounding jar 101 in the compounding process too with the help of manpower, can make the inside mixing jar 101 carry out the mixed efficiency of mixing, fully practical.

The inside of the shell 201 is located between two rotating rods 204 and is rotationally connected with a rotating shaft 207 through a bearing, a rotating gear 208 is fixedly arranged on one side of the outer part of the rotating shaft 207, the rotating gear 208 is in meshed connection with two half gears 206, the two rotating rods 204 and the outer part of the rotating shaft 207 are rotationally connected with a locating plate 209 through bearings, the locating plate 209 is fixedly connected with the shell 201, the rotating gear 208 can reciprocally rotate, a sector gear 210 is arranged above the shell 201, the sector gear 210 is in meshed connection with the rotating gear 208, a mounting plate 211 is fixedly arranged at the top of the sector gear 210, a fixing rod 212 is fixedly arranged at the top of the mounting plate 211, a sliding groove 2121 is formed in the inner part of the fixing rod 212, a sliding rod 213 is fixedly connected with a column block 104, the mixing barrel 101 can be driven to reciprocally swing, two groups of fixing blocks 214 are symmetrically arranged on two sides of the mounting plate 211, two groups of fixing blocks 214 are respectively fixedly arranged between the two groups 215, a sliding sleeve 216 is sleeved on the outer part of the sliding rod 215, and the sliding sleeve 216 is fixedly connected with the fixing rod 210, the sliding sleeve 216 is fixedly arranged on the top of the mounting plate 211, and the sliding sleeve 211 is fixedly connected with the sliding rod 211.

Mixing component 3 includes mounting bracket 301 of fixed mounting at mixing drum 101 top, and the inside fixed mounting of mounting bracket 301 has second motor 302, and the output fixed mounting of second motor 302 has (mixing) shaft 303, and (mixing) shaft 303) is rotated with mixing drum 101 through the bearing and is connected, and the bottom of (mixing) shaft 303 is rotated through the bearing and is connected with installation pole 304, and installation pole 304 and mixing drum 101 fixed connection, can be further mix the material through mixing component 3, promote the mixing effect of material, make the compounding more even quick, the outside symmetry of (mixing) shaft 303) installs a plurality of first stirring vane 305, and the top of installation pole 304 is rotated through the bearing symmetry and is connected with movable rod 306, and two movable rods 306 pass through the bearing and are connected with mixing drum 101 rotation, and the top of two movable rods 306 all passes mixing drum 101 and fixed mounting have second band pulley 309, and the outside one side of two movable rods 306 all is fixedly mounted with a plurality of second stirring vane 307, and the outside top fixed mounting of stirring shaft 303 has first band pulley 308, and first band pulley 308 passes through the rotation belt 217 to be connected with second band pulley 309, make mixing drum 217 and two movable rod 306 and movable rod 215 are connected with one side of fan-shaped spring and one end of reset spring 210, reset spring and one side of reset spring pair are fixed connection, reset spring pair is fixed with one side of reset spring 210 simultaneously.

Working principle: before the mixer for preparing the clofarabine is used, the whole condition of the mixer needs to be checked firstly to determine that normal work can be carried out, according to the figures 1-5, when the rotating assemblies 2 are symmetrically arranged at two sides of the mixing drum 101 to prepare the clofarabine, raw materials are poured into the mixing drum 101 from the feeding hole 102, then the first motor 203 is started to drive the two-way worm 202 to rotate in the shell 201, the two rotating rods 204 can be driven to rotate in the shell 201 through the meshing of the two-way worm 202 and the worm wheel 205, the two half gears 206 can be driven to rotate reversely at the same time, the half gears 206 on one side can be meshed to drive the rotating gear 208 to rotate after the meshing of the teeth on the half gear 206 on the other side with the rotating gear 208 is completed, the half gears 206 on the other side can be meshed with the rotating gear 208 to enable the rotating gear 208 to rotate reversely, the rotating gear 208 can further reciprocate, the rotating gear 208 can drive the sector gear 210 to reciprocate through the meshing with the sector gear 210 after reciprocating rotation, the mounting plate 211 and the fixed rod 212 drive the sliding rod 213 to rotate, the sliding rod 213 is fixedly connected with the column block 104, the column block 104 and the mixing drum 101 rotate on the fixed frame 105, the mixing drum 101 can further reciprocate, the sector gear 210 can drive the sliding sleeve 216 to slide on the sliding rod 215 while swinging, the sliding rod 213 slides in the sliding groove 2121, the reset spring 217 can restore deformation, the sector gear 210 can always cling to the rotating gear 208, the rotating gear 208 can drive the sector gear 210 while the mixing drum 101 swings, the mixing drum 101 can reciprocate without the help of manpower in the mixing process through the rotating component 2, the materials in the mixing barrel 101 can be fully mixed and stirred, so that the working efficiency and the practicability are improved;

The inside and the top at compounding bucket 101 have set up compounding subassembly 3, can at first start second motor 302 drive (mixing) shaft 303 when mixing the material and rotate on installation pole 304, stirring shaft 303 can drive first band pulley 308 rotation when rotating, first band pulley 308 can drive the second band pulley 309 through the belt and rotate for two movable rods 306 rotate, make two sets of first stirring vane 305 and two sets of second stirring vane 307 rotate, and first stirring vane 305 and the crisscross setting of second stirring vane 307, can further mix the material through compounding subassembly 3, promote the mixing effect of material, make the compounding more even quick.

Although the present utility model has been described with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements and changes may be made without departing from the spirit and principles of the present utility model.

Claims

1. A mixing device for preparing clofarabine comprises two supporting frames (1) and a mixing barrel (101);

A feeding hole (102) is formed in the upper part of one side of the mixing barrel (101) in a penetrating manner, and a discharging hole (103) is formed in the bottom of the mixing barrel (101) in a penetrating manner;

Characterized by further comprising:

Column blocks (104) are symmetrically arranged above two sides of the mixing barrel (101), one sides of the two column blocks (104) are respectively connected with a fixing frame (105) through bearings in a rotating mode, the two fixing frames (105) are respectively and fixedly connected with the two supporting frames (1), rotating assemblies (2) are symmetrically arranged below two sides of the mixing barrel (101), and mixing assemblies (3) are arranged inside and at the top of the mixing barrel (101);

the rotating assembly (2) comprises a shell (201) fixedly arranged at one side of the top of the supporting frame (1), a bidirectional worm (202) is rotatably connected to one side above the interior of the shell (201) through a bearing, one end of the bidirectional worm (202) penetrates through the shell (201) and is fixedly provided with a first motor (203), and the first motor (203) is fixedly connected with the shell (201);

Wherein, inside both sides of casing (201) are connected with dwang (204) through bearing symmetry rotation, and outside one side of two dwang (204) is all fixed mounting has worm wheel (205) to two worm wheel (205) all are connected with two-way worm (202) meshing, and outside opposite side of two dwang (204) is all fixed mounting has half gear (206).

2. A mixer for preparing clofarabine according to claim 1, wherein: the inside of casing (201) is located and is connected with axis of rotation (207) through the bearing rotation between two dwang (204), and outside one side fixed mounting of axis of rotation (207) has rotation gear (208) to rotation gear (208) and two half gears (206) meshing are connected, and the outside of two dwang (204) and axis of rotation (207) all is connected with locating plate (209) through the bearing rotation, and locating plate (209) and casing (201) fixed connection moreover.

3. A mixer for preparing clofarabine according to claim 1, wherein: the top of casing (201) is provided with sector gear (210), and sector gear (210) and rotation gear (208) meshing are connected to the top fixed mounting of sector gear (210) has mounting panel (211), and the top fixed mounting of mounting panel (211) has dead lever (212) moreover, and sliding groove (2121) has been seted up to the inside of dead lever (212) to sliding connection in sliding groove (2121) has slide bar (213), and slide bar (213) and post piece (104) fixed connection.

4. A mixer for preparing clofarabine according to claim 1, wherein: two groups of fixing blocks (214) are symmetrically arranged on two sides of the mounting plate (211) of the mixing barrel (101), two groups of sliding rods (215) are respectively and fixedly arranged between the two groups of fixing blocks (214), sliding sleeves (216) are sleeved outside the sliding rods (215), and the sliding sleeves (216) are fixedly connected with the mounting plate (211).

5. A mixer for preparing clofarabine according to claim 1, wherein: mixing subassembly (3) are including mounting bracket (301) of fixed mounting at compounding bucket (101) top, and the inside fixed mounting of mounting bracket (301) has second motor (302), and the output fixed mounting of second motor (302) has (mixing) shaft (303), and (mixing) shaft (303) are connected with compounding bucket (101) rotation through the bearing moreover, and the bottom of (mixing) shaft (303) is connected with installation pole (304) through the bearing rotation, and installation pole (304) and compounding bucket (101) fixed connection.

6. A mixer for clofarabine preparation according to claim 5, wherein: the outside symmetry of (303) stirring axle installs a plurality of first stirring vane (305), and the top of installation pole (304) is connected with movable rod (306) through bearing symmetry rotation, and two movable rods (306) are connected with compounding bucket (101) rotation through the bearing, and the top of two movable rods (306) all passes compounding bucket (101) and fixed mounting have second band pulley (309), and the outside one side of two movable rods (306) all fixed mounting has a plurality of second stirring vane (307), and the outside top fixed mounting of (303) stirring axle has first band pulley (308), and first band pulley (308) are connected with second band pulley (309) rotation through the belt moreover.

7. A mixer for clofarabine preparation according to claim 4, wherein: and one side of the outer part of each sliding rod (215) is sleeved with a return spring (217), one end of each return spring (217) is fixedly connected with the sliding sleeve (216), and the other end of each return spring (217) is fixedly connected with one side fixing block (214).