CN221148089U - Liver cancer tissue pathological section device - Google Patents
Liver cancer tissue pathological section device Download PDFInfo
- Publication number
- CN221148089U CN221148089U CN202322899751.9U CN202322899751U CN221148089U CN 221148089 U CN221148089 U CN 221148089U CN 202322899751 U CN202322899751 U CN 202322899751U CN 221148089 U CN221148089 U CN 221148089U
- Authority
- CN
- China
- Prior art keywords
- refrigerating sheet
- support
- blade
- paraffin
- liver cancer
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 201000007270 liver cancer Diseases 0.000 title claims abstract description 25
- 208000014018 liver neoplasm Diseases 0.000 title claims abstract description 24
- 230000001575 pathological effect Effects 0.000 title claims abstract description 20
- 239000012188 paraffin wax Substances 0.000 claims abstract description 55
- 238000005520 cutting process Methods 0.000 claims abstract description 14
- 238000005057 refrigeration Methods 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 230000005540 biological transmission Effects 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 8
- 238000001816 cooling Methods 0.000 abstract description 7
- 210000001519 tissue Anatomy 0.000 description 50
- 230000000694 effects Effects 0.000 description 6
- 238000007710 freezing Methods 0.000 description 5
- 230000008014 freezing Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 239000004065 semiconductor Substances 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 3
- 210000003494 hepatocyte Anatomy 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 210000005229 liver cell Anatomy 0.000 description 3
- 210000005228 liver tissue Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000017525 heat dissipation Effects 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 241001052560 Thallis Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 210000002372 intrahepatic bile duct epithelial cell Anatomy 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
Abstract
The utility model relates to a liver cancer tissue pathological section device, which belongs to the field of pathological tissue and cell tissue detection analysis auxiliary section equipment and comprises a support, wherein a cutter holder is connected with the support in a sliding manner in the horizontal direction, a blade is detachably arranged on the cutter holder, and a screw rod for driving the cutter holder to slide is arranged between the cutter holder and the support. The support plumb direction sliding connection has the clamping assembly who is used for centre gripping paraffin tissue piece. The clamping assembly comprises a supporting frame, a refrigerating sheet capable of sliding along the direction perpendicular to the cutting edge of the blade is arranged on the supporting frame, and the refrigerating sheet is connected with the supporting frame through a spring. The device comprises a cooling plate, a control device, a power supply component, a cooling plate and a control device.
Description
Technical Field
The utility model relates to a liver cancer tissue pathological section device, and belongs to the field of pathological tissue and cell tissue detection analysis auxiliary section equipment.
Background
Liver cancer is a short term for primary liver cancer, and is a malignant tumor that occurs by hepatocytes or intrahepatic bile duct epithelial cells. Paraffin slicing is the most widely used method in the conventional slice making technology of histology, and before the detection experiment, liver cancer tissue cells are embedded into paraffin liver cell tissue blocks through paraffin, then freezing treatment is carried out, then paraffin embedded with liver cancer tissue cells is further sliced, and the slice is placed under a microscope for observation and comparison analysis. In the paraffin block slicing process, a slicer is required.
In the existing slicing device, the frozen paraffin blocks are easy to cool or the paraffin blocks are gradually cooled at normal temperature due to friction between a cutter and the paraffin blocks in the slicing process of the paraffin blocks. The paraffin block embedded in the liver cell tissue is easy to soften, so that the liver cancer tissue is softened, and the slicing is easy to be uneven.
Patent CN214213924U is a liver cancer histopathological section device, and it provides cold wind through the air-cooler, carries out the jetting cooling to the cutter of section device to prevent that paraffin piece from softening. However, the temperature of the paraffin block cannot be effectively reduced and maintained by cooling only the tool.
Disclosure of utility model
In order to overcome the problems in the background art, the utility model provides a liver cancer tissue pathological section device, wherein a semiconductor refrigeration sheet is arranged on a component for clamping a paraffin block and used for absorbing the temperature of the paraffin block, maintaining the freezing effect of the paraffin block and ensuring that even liver cell tissue sheets for detection are cut out.
In order to solve the problems, the utility model is realized by the following technical scheme: the liver cancer histopathological section device comprises a support, wherein a cutter holder is connected with the support in a sliding manner in the horizontal direction, a blade is detachably arranged on the cutter holder, and a screw rod for driving the cutter holder to slide is arranged between the cutter holder and the support;
The clamping assembly for clamping the paraffin tissue blocks is slidably connected in the plumb direction of the support, an eccentric wheel is arranged on one side of the support and hinged to one end of a connecting rod, the other end of the connecting rod is hinged to the clamping assembly, and the rotating eccentric wheel can enable the transmission clamping assembly to slide up and down to drive the paraffin tissue blocks to be scraped by the blade;
The clamping assembly comprises a support frame, a refrigerating sheet capable of sliding along the direction perpendicular to the cutting edge of the blade is arranged on the support frame, and the refrigerating sheet is connected with the support frame through a spring;
A clamp for clamping the paraffin tissue block is arranged on one side of the refrigerating sheet, a radiating rib sheet is fixedly arranged on the other side of the refrigerating sheet, a fan electrically connected with the control device is arranged on one side of the radiating rib sheet, which is away from the refrigerating sheet, a power supply component for providing electric energy for the control device is also arranged on the tool apron, and the power supply component and the refrigerating sheet are respectively electrically connected with the control device;
Further, an adjusting handle for limiting the rebound range of the refrigerating sheet is connected to the supporting frame through threads, and the adjusting handle is slidably arranged on a limiting plate for limiting the refrigerating sheet in a penetrating mode;
Further, the clamp is slidably connected with the refrigerating sheet and is provided with a spring which is connected with the refrigerating sheet, and the clamp is pressed against the paraffin tissue block to be tightly attached to the refrigerating sheet through resilience of the spring;
Further, be provided with the fixed block on the blade holder, be provided with the elasticity preforming on the fixed block for the centre gripping is fixed the blade, the fixed block has the inclined plane of direction pathological tissue section, and the lower extreme on inclined plane is provided with the collecting vat that is used for holding water, pathological tissue section falls in the aquatic along the inclined plane.
The beneficial effects of the utility model are as follows: according to the utility model, the semiconductor refrigeration piece is arranged on the clamping component for clamping the paraffin block, and the refrigeration piece is tightly attached to the paraffin tissue block to absorb the temperature on the paraffin tissue block, so that the freezing effect of the paraffin block is maintained, and the uniform cut of the hepatocyte tissue block for detection is ensured. Meanwhile, the paraffin tissue block is driven to be cut by the fixedly mounted blade through the eccentric wheel and the connecting rod mechanism, and compared with the prior art that the cutting tool is adopted for moving cutting, the cutting uniformity of the paraffin tissue block can be effectively improved.
Drawings
FIG. 1 is a schematic diagram of the overall structure of a liver cancer histopathological section device;
FIG. 2 is a partial cross-sectional view of a liver cancer histopathological section device;
FIG. 3 is a perspective view of a clamping assembly of a liver cancer histopathological section device;
FIG. 4 is another view of a clamping assembly of a liver cancer histopathological section device;
fig. 5 is a partial perspective view of a tool apron of a liver cancer histopathological section device.
Reference numerals illustrate: 1. a support; 2. a tool apron; 201. a fixed block; 2011. elastic tabletting; 2012. a blade; 202. a collection tank; 203. a screw rod; 3. a clamping assembly; 301. a support frame; 3011. an adjusting handle; 302. a cooling sheet; 3021. a clamp; 3022. a heat radiation ridge plate; 3023. a fan; 3024. a limiting plate; 4. a connecting rod; 5. an eccentric wheel; 6. operating a hand wheel; 7. paraffin tissue blocks; 8. and a control device.
Detailed Description
In order to make the objects, technical solutions, and achievement of the objects and effects of the present utility model comprehensible, preferred embodiments accompanied with figures are described in detail below for understanding by a skilled person.
It should be noted that, in the description of the present utility model, unless explicitly specified or limited, terms such as "mounted," "connected," and the like are to be construed broadly and may be either fixed or removable; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium.
The direction a in fig. 2 is the plumb direction (vertically upward direction), and the direction B is the horizontal direction (or the tool moving direction or the tissue mass moving direction).
Referring to fig. 1 to 5, the present utility model is mainly used for cutting paraffin tissue blocks 7 (or liver pathological paraffin blocks, i.e. paraffin blocks embedding liver tissue cells), and obtaining thinner slices for processing and detecting and comparing, observing and analyzing. A semiconductor refrigeration sheet 302 is provided on the assembly holding the paraffin block to absorb the temperature of the paraffin block, maintain the freezing effect of the paraffin block, and ensure uniform cut out of the hepatocyte tissue sheet for detection.
As shown in fig. 1, the liver cancer histopathological section device comprises a support 1, a cutter holder 2 is slidably connected to the support 1 in the horizontal direction, a blade 2012 is detachably mounted on the cutter holder 2, and a screw 203 for driving the cutter holder 2 to slide is further arranged between the cutter holder 2 and the support 1, so that the blade 2012 can move towards the direction of the paraffin tissue block 7. The cutting edge of the moving blade 2012 is just attached to the outer wall of the paraffin block 7, i.e., as the zero point position (or reference position) of the blade 2012.
As shown in fig. 1 and 2, a clamping component 3 for clamping a paraffin tissue block 7 is slidably connected in the plumb direction of the support 1, one side of the support 1 is provided with an eccentric wheel 5, and the eccentric wheel 5 is coaxially and fixedly connected with an operation hand wheel 6. The eccentric wheel 5 is hinged to one end of the connecting rod 4, the other end of the connecting rod 4 is hinged to the clamping assembly 3, the eccentric wheel 5 is rotated through the operation hand wheel 6, the transmission clamping assembly 3 can slide up and down, the paraffin tissue block 7 is driven to move up and down, and accordingly the paraffin tissue block is scraped by the blade 2012. The structure is arranged, and compared with the prior art that the paraffin tissue block 7 is cut by moving the cutter, the cutting uniformity of the paraffin tissue block 7 can be effectively improved. And this structure arrangement can effectively improve the continuity of the up-and-down motion of the blade 2012, ensure that the cut liver pathological tissue slices have uniform thickness, and ensure the consistency of the thickness. When the liver pathological tissue section is placed on a microscope stage, the section has better ductility.
As shown in fig. 3 and 4, the clamping assembly 3 includes a supporting frame 301, a refrigerating plate 302 is provided on the supporting frame 301 and can slide along the direction perpendicular to the cutting edge of the blade 2012, and the refrigerating plate 302 is also connected with the supporting frame 301 through a spring. And the support 301 is connected with an adjusting handle 3011 for limiting the rebound range of the refrigerating sheet 302 in a threaded manner, and the adjusting handle 3011 is slidably arranged in a limiting plate 3024 for limiting the refrigerating sheet 302 in a penetrating manner. When slicing is needed, the limiting plate 3024 can be pushed forward by twisting the adjusting handle 3011, so that the limiting plate 3024 compresses the spring and drives the paraffin tissue block 7 to move forward, thereby controlling the spacing (or displacement) of the paraffin tissue block 7 beyond the cutting edge, and cutting the paraffin tissue slice with the spacing (displacement) being the thickness of the paraffin tissue slice. Simultaneously, the resilience of the refrigerating sheet 302 is limited, and the paraffin tissue block 7 on the refrigerating sheet 302 can be cut in a rebound mode, so that rigid displacement of the liver tissue slice in the cutting process is reduced, and the slice is prevented from being wrinkled.
As shown in fig. 3 and 4, a clamp 3021 for clamping the paraffin tissue block 7 is arranged on one side of the refrigeration sheet 302, the clamp 3021 is slidably connected to the refrigeration sheet 302, a spring is arranged to be connected with the refrigeration sheet 302, the clamp 3021 compresses the paraffin tissue block 7 tightly to the refrigeration sheet 302 through spring resilience, and the heat transfer efficiency of the refrigeration sheet 302 and the paraffin tissue block 7 is improved. Meanwhile, the structure is convenient to install and detach the paraffin tissue block 7, so that the cutting efficiency is improved. Further avoiding the paraffin block 7 from increasing in temperature by prolonged contact with the operator's limb during installation after removal from the refrigerator.
As shown in fig. 3 and 4, a heat dissipation ridge 3022 is fixedly mounted on the other side of the cooling fin 302, a fan 3023 electrically connected to the control device 8 is disposed on a side of the heat dissipation ridge 3022 facing away from the cooling fin 302, and a power supply unit for supplying electric energy to the control device 8 is further disposed on the tool apron 2. The control device 8 is configured as a single-chip microcomputer or a logic controller, and is used for controlling the start and stop of the fan 3023, and the power supply component is configured as a power connector or a battery block, and is used for providing electric energy for the single-chip microcomputer or the logic controller. The power supply unit and the refrigerating sheet 302 are respectively and electrically connected to the control device 8, and power is supplied to the refrigerating sheet 302 through the power supply unit (battery block), and the refrigerating sheet 302 is configured as a semiconductor refrigerating sheet 302, so that the refrigerating effect can be further improved, the freezing effect of the paraffin tissue block 7 is maintained, and the uniformity of slicing is ensured. Meanwhile, the control device 8 controls the start and stop of the refrigerating sheet 302, so that the fan 3023 is ensured to start before the refrigerating sheet 302, and then the refrigerating sheet 302 is stopped, and the service life of the refrigerating sheet 302 is prolonged.
As shown in fig. 5, the fixing block 201 is disposed on the tool apron 2, and the elastic pressing sheet 2011 is disposed on the fixing block 201 for clamping and fixing the blade 2012, the structure can facilitate the disassembly and disinfection of the blade 2012, and avoid the influence of thalli or other microorganisms on the blade 2012 on the liver tissue block slice, thereby improving the detection accuracy of liver cancer pathological tissues and further eliminating the influence of other factors.
The fixed block 201 has a slope guiding the pathological tissue section, the lower end of which is provided with a collecting tank 202 for holding water, as shown in fig. 5, and the pathological tissue section falls into the water along the slope. When the liver cancer pathological tissue block is folded, the slice gradually extends in water, so that the pathological tissue block is conveniently and directly clamped by forceps from the collecting tank 202 to be treated and conveniently placed on a glass slide, the observation is convenient, and the detection efficiency of the liver cancer pathological tissue slice is improved.
Finally, it is noted that the above-mentioned preferred embodiments are only intended to illustrate rather than limit the utility model, and that, although the utility model has been described in detail by means of the above-mentioned preferred embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the scope of the utility model as defined by the appended claims.
Claims (4)
1. A liver cancer histopathological section device, which is characterized in that: the tool rest comprises a support (1), wherein the support (1) is connected with a tool rest (2) in a sliding manner in the horizontal direction, a blade (2012) is detachably arranged on the tool rest (2), and a screw rod (203) for driving the tool rest (2) to slide is further arranged between the tool rest (2) and the support (1);
The clamping assembly (3) for clamping the paraffin tissue block (7) is slidingly connected in the plumb direction of the support (1), an eccentric wheel (5) is arranged on one side of the support (1), the eccentric wheel (5) is hinged to one end of the connecting rod (4), the other end of the connecting rod (4) is hinged to the clamping assembly (3), the eccentric wheel (5) is rotated to enable the transmission clamping assembly (3) to slide up and down, and the paraffin tissue block (7) is driven to be scraped by the blade (2012);
The clamping assembly (3) comprises a supporting frame (301), a refrigerating sheet (302) capable of sliding along the direction perpendicular to the cutting edge of the blade (2012) is arranged on the supporting frame (301), and the refrigerating sheet (302) is also connected with the supporting frame (301) through a spring;
One side of the refrigerating sheet (302) is provided with a clamp (3021) for clamping the paraffin tissue block (7) to cling to the clamp, the other side of the refrigerating sheet is fixedly provided with a radiating rib (3022), one side of the radiating rib (3022) opposite to the refrigerating sheet (302) is provided with a fan (3023) electrically connected to the control device (8), the tool apron (2) is further provided with a power supply component for supplying electric energy to the control device (8), and the power supply component and the refrigerating sheet (302) are electrically connected to the control device (8) respectively.
2. The liver cancer histopathological section device of claim 1, wherein: the support frame (301) is connected with an adjusting handle (3011) used for limiting the rebound range of the refrigerating sheet (302) in a threaded mode, and the adjusting handle (3011) is slidably arranged on a limiting plate (3024) used for limiting the refrigerating sheet (302) in a penetrating mode.
3. The liver cancer histopathological section device of claim 2, wherein: the clamp (3021) is slidably connected to the refrigeration piece (302) and is provided with a spring connected with the refrigeration piece (302), and the clamp (3021) is used for pressing the paraffin tissue block (7) tightly against the refrigeration piece (302) through spring resilience.
4. The liver cancer histopathological section device according to any one of claims 1 to 3, wherein: be provided with fixed block (201) on blade holder (2), be provided with elasticity preforming (2011) on fixed block (201) for the centre gripping is fixed blade (2012), fixed block (201) have the inclined plane of direction pathological tissue section, and the lower extreme on inclined plane is provided with collecting vat (202) that are used for holding water, pathological tissue section falls in the aquatic along the inclined plane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322899751.9U CN221148089U (en) | 2023-10-27 | 2023-10-27 | Liver cancer tissue pathological section device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322899751.9U CN221148089U (en) | 2023-10-27 | 2023-10-27 | Liver cancer tissue pathological section device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221148089U true CN221148089U (en) | 2024-06-14 |
Family
ID=91389351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322899751.9U Active CN221148089U (en) | 2023-10-27 | 2023-10-27 | Liver cancer tissue pathological section device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221148089U (en) |
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2023
- 2023-10-27 CN CN202322899751.9U patent/CN221148089U/en active Active
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