CN221064854U - Automatic separating device for biological sample laser cutting - Google Patents
Automatic separating device for biological sample laser cutting Download PDFInfo
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- CN221064854U CN221064854U CN202322682520.2U CN202322682520U CN221064854U CN 221064854 U CN221064854 U CN 221064854U CN 202322682520 U CN202322682520 U CN 202322682520U CN 221064854 U CN221064854 U CN 221064854U
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- 239000012472 biological sample Substances 0.000 title claims abstract description 52
- 238000003698 laser cutting Methods 0.000 title claims abstract description 47
- 239000012535 impurity Substances 0.000 claims abstract description 28
- 238000005070 sampling Methods 0.000 claims abstract description 28
- 230000007246 mechanism Effects 0.000 claims abstract description 22
- 238000000926 separation method Methods 0.000 claims abstract description 22
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 24
- 239000000523 sample Substances 0.000 claims description 19
- 230000002457 bidirectional effect Effects 0.000 claims description 9
- 238000009434 installation Methods 0.000 claims description 2
- 238000005520 cutting process Methods 0.000 abstract description 21
- 230000000694 effects Effects 0.000 abstract description 16
- 229910052799 carbon Inorganic materials 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 230000008569 process Effects 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 238000001215 fluorescent labelling Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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Abstract
The utility model provides an automatic separation device for biological sample laser cutting. The automatic separation device for the laser cutting of the biological sample comprises: a working box; the supporting plate is fixedly arranged in the working box; the electric guide rail is fixedly arranged at the bottom of the supporting plate; the laser cutting head is fixedly arranged on the output block of the electric guide rail; the gas impurity removing mechanism is arranged in the working box and used for removing impurities from gas; and the lifting sampling mechanism is arranged in the working box and used for taking out samples. The automatic separation device for the laser cutting of the biological sample has the advantages of being capable of adsorbing and removing impurities contained in the gas and improving the cutting effect.
Description
Technical Field
The utility model belongs to the technical field of biological sample separation, and particularly relates to an automatic separation device for biological sample laser cutting.
Background
The current laser micro-cutting technology uses ultraviolet band laser with high-frequency low-energy pulse to cut biological samples, so that the loss of the samples is reduced to the minimum. The principle of the laser micro-cutting technology is as follows: the accurate position of the target cells or the target tissues is rapidly confirmed by a fluorescence labeling microscopic imaging method, the coaxial ultraviolet laser is precisely controlled to conduct microscopic cutting according to the position coordinate parameters, and the separation of the target cells or the target tissues into the culture dish is achieved by combining the safety of membrane adhesion separation.
When biological sample laser cutting process, need use under dry, ventilation, dustless environment, but because current biological sample laser cutting device is mostly operated on the workstation, still contains a lot of impurity in specific cutting process because in the gas, produces certain influence to the cutting effect of laser easily, influences cutting efficiency.
Therefore, it is necessary to provide a new automatic separation device for laser cutting of biological samples to solve the above technical problems.
Disclosure of utility model
The utility model provides an automatic separation device for biological sample laser cutting, which aims to solve the technical problem that the laser cutting effect is reduced because the gas also contains a lot of impurities in the biological sample laser cutting process.
The utility model provides an automatic separation device for biological sample laser cutting, which comprises: a working box; the supporting plate is fixedly arranged in the working box; the electric guide rail is fixedly arranged at the bottom of the supporting plate; the laser cutting head is fixedly arranged on the output block of the electric guide rail; the gas impurity removing mechanism is arranged in the working box and used for removing impurities from gas; and the lifting sampling mechanism is arranged in the working box and used for taking out samples.
As a further scheme of the utility model, the air impurity removing mechanism comprises a fan, a purifying box, a plurality of first sliding grooves, a plurality of active carbon plates, a cavity and a plurality of air suction ports, wherein the fan is fixedly arranged at the top end of the supporting plate, the purifying box is fixedly arranged on the inner wall of the top of the working box, the exhaust end of the fan is communicated with the purifying box, the plurality of first sliding grooves are formed in the purifying box, the plurality of active carbon plates are respectively and correspondingly arranged in the plurality of first sliding grooves, the cavity is formed in the working box, the air inlet end of the fan is communicated with the cavity, and the plurality of air suction ports are formed in the cavity.
As a further scheme of the utility model, the lifting sampling mechanism comprises a hydraulic rod, a fixing plate, a mounting seat and a plurality of sampling needles, wherein the hydraulic rod is fixedly arranged on the inner wall of the top of the working box, the fixing plate is fixedly arranged on the output rod of the hydraulic rod, the mounting seat is arranged at the bottom of the fixing plate, and the sampling needles are arranged on the mounting seat.
As a further scheme of the utility model, two clamping strips are fixedly arranged at the top of the mounting seat, two clamping grooves are formed in the bottom of the fixing plate, the two clamping grooves are respectively and correspondingly arranged with the two clamping strips, a bolt is slidably arranged on the fixing plate, and the bolt penetrates through the two clamping strips.
As a further scheme of the utility model, a sliding block is slidably arranged on the inner wall of the bottom of the working box, a second sliding groove is formed in the sliding block, a bidirectional screw rod is rotatably arranged in the second sliding groove, two clamping plates are arranged on the bidirectional screw rod in a threaded manner, and a handle is fixedly arranged at one end of the bidirectional screw rod.
As a further scheme of the utility model, the slide block is provided with a sample carrying plate, the sample carrying plate is provided with a plurality of grooves, and biological samples are arranged in the grooves.
As a further scheme of the utility model, the one-way screw rod is rotatably arranged in the working box and is in threaded connection with the sliding block, a motor is fixedly arranged on the outer wall of one side of the working box, and an output shaft of the motor is fixedly connected with a rotating shaft of the one-way screw rod.
Compared with the related art, the automatic separation device for the laser cutting of the biological sample has the following beneficial effects:
the utility model provides an automatic separation device for biological sample laser cutting, which comprises:
1. The electric guide rail drives the laser cutting head to move, so that a biological sample in the groove is cut, the cutting surface is wider, the cutting effect is better, the suction port on the cavity is used for sucking impurity gas in the box body through the suction opening of the fan in the gas impurity removing mechanism, the gas is then introduced into the purifying box and adsorbed and purified through the activated carbon plate, and finally the gas is discharged into the working box again, so that the gas impurity removing and purifying effect is better, and the first chute is directly replaced by pulling the activated carbon plate in the first chute, so that the replacing mode is simpler and more convenient, and the operation is easy;
2. The output rod of the hydraulic rod in the lifting sampling mechanism drives the fixing plate and the mounting seat to descend, so that the sampling needle can sample biological samples in the groove, the sampling operation is simple and convenient, the height is easy to adjust, the clamping strip is detached from the clamping groove through the drawing bolt, and the mounting seat and the sampling needle are detached and replaced, so that the detachment and replacement process is simple and convenient;
3. The bidirectional screw is driven to rotate through the torsion handle, the driving clamping plate moves in the second sliding groove, so that the carrying plate is clamped on the sliding block, the position of the carrying plate is prevented from shifting when moving, the effect of laser cutting is influenced, the biological sample is reduced by arranging the biological sample in the groove, the influence of the biological sample before being cut is reduced, the unidirectional screw is driven to start to rotate through the output shaft of the motor, the driving sliding block drives the carrying plate to move, and the laser cutting head can continuously cut the biological sample, so that the cutting efficiency of the device is improved.
Drawings
The present utility model is further described below with reference to the accompanying drawings for the convenience of understanding by those skilled in the art.
FIG. 1 is a schematic cross-sectional elevation view of a biological sample laser cutting automated separation device according to a preferred embodiment of the present utility model;
FIG. 2 is an enlarged schematic view of the portion A in FIG. 1;
FIG. 3 is an enlarged schematic view of the portion B of FIG. 1;
fig. 4 is an enlarged schematic view of the portion C in fig. 1.
In the figure: 1. a working box; 2. a support plate; 3. an electric guide rail; 4. a laser cutting head; 5. a blower; 6. a purifying box; 7. a first chute; 8. an activated carbon plate; 9. a cavity; 10. an air suction port; 11. a hydraulic rod; 12. a fixing plate; 13. a mounting base; 14. a sampling needle; 15. clamping strips; 16. a clamping groove; 17. a plug pin; 18. a slide block; 19. a second chute; 20. a clamping plate; 21. carrying a template; 22. a groove; 23. a biological sample; 24. a unidirectional screw; 25. a motor; 26. a bidirectional screw.
Detailed Description
Referring to fig. 1 to fig. 4 in combination, fig. 1 is a schematic front sectional view of a preferred embodiment of an automatic separation device for laser cutting biological samples according to the present utility model; FIG. 2 is an enlarged schematic view of the portion A in FIG. 1; FIG. 3 is an enlarged schematic view of the portion B of FIG. 1; fig. 4 is an enlarged schematic view of the portion C in fig. 1.
The automatic separation device for the laser cutting of the biological sample comprises: a working box 1; a supporting plate 2, wherein the supporting plate 2 is fixedly arranged in the working box 1; an electric guide rail 3, wherein the electric guide rail 3 is fixedly arranged at the bottom of the supporting plate 2; the laser cutting head 4 is fixedly arranged on the output block of the electric guide rail 3; the gas impurity removing mechanism is arranged in the working box 1 and used for removing impurities from gas; the lifting sampling mechanism is arranged in the working box 1 and used for taking out samples, and the electric guide rail 3 drives the laser cutting head 4 to move so as to cut the biological samples 23 in the grooves 22, so that the cutting surface is wider and the cutting effect is better.
The air impurity removing mechanism comprises a fan 5, a purifying box 6, a plurality of first sliding grooves 7, a plurality of active carbon plates 8, a cavity 9 and a plurality of air inlets 10, wherein the fan 5 is fixedly arranged at the top end of the supporting plate 2, the purifying box 6 is fixedly arranged on the inner wall of the top of the working box 1, the air exhaust end of the fan 5 is communicated with the purifying box 6, the plurality of first sliding grooves 7 are formed in the purifying box 6, the plurality of active carbon plates 8 are respectively and correspondingly arranged in the plurality of first sliding grooves 7, the cavity 9 is formed in the working box 1, the air inlet end of the fan 5 is communicated with the cavity 9, the plurality of air inlets 10 are formed in the cavity 9, the air inlets 10 in the cavity 9 are enabled to suck impurity air in the working box through the air inlet 5 in the air impurity removing mechanism, then the air is led into the purifying box 6 to be adsorbed and purified through the active carbon plates 8, and finally the air is discharged into the working box 1 again, the air impurity removing purifying effect is good, and the air impurity removing and purifying effect is easy, and the air in the mode of directly replacing the active carbon plates 8 in the working box is replaced by means of simple and convenient.
The lifting sampling mechanism comprises a hydraulic rod 11, a fixed plate 12, a mounting seat 13 and a plurality of sampling needles 14, wherein the hydraulic rod 11 is fixedly installed on the inner wall of the top of the working box 1, the fixed plate 12 is fixedly installed on the output rod of the hydraulic rod 11, the mounting seat 13 is arranged at the bottom of the fixed plate 12, the sampling needles 14 are all arranged on the mounting seat 13, the output rod of the hydraulic rod 11 in the lifting sampling mechanism drives the fixed plate 12 and the mounting seat 13 to descend, so that the sampling needles 14 can sample biological samples 23 in the grooves 22, the sampling operation is simple and convenient, and the height is easy to adjust.
Two clamping bars 15 are fixedly arranged at the top of the mounting seat 13, two clamping grooves 16 are formed in the bottom of the fixing plate 12, two clamping grooves 16 are respectively and correspondingly arranged with two clamping bars 15, a bolt 17 is slidably arranged on the fixing plate 12, the bolt 17 penetrates through the two clamping bars 15, the clamping bars 15 are detached from the clamping grooves 16 through the pulling bolt 17, and accordingly the mounting seat 13 and the sampling needle 14 are detached and replaced, and the detachment and replacement process is simple.
The sliding block 18 is slidably mounted on the inner wall of the bottom of the working box 1, the second sliding groove 19 is formed in the sliding block 18, the two-way screw rod 26 is rotatably mounted in the second sliding groove 19, two clamping plates 20 are mounted on the two-way screw rod 26 in a threaded manner, a handle is fixedly mounted at one end of the two-way screw rod 26, the two-way screw rod 26 is driven to rotate through twisting the handle, the clamping plates 20 are driven to move in the second sliding groove 19, and accordingly the sample carrying plate 21 is clamped on the sliding block 18, and the position of the sample carrying plate 21 is prevented from shifting when moving, so that the effect of laser cutting is influenced.
The slide block 18 is provided with a sample carrying plate 21, the sample carrying plate 21 is provided with a plurality of grooves 22, a plurality of biological samples 23 are arranged in the grooves 22, and the biological samples 23 are arranged in the grooves 22, so that the influence of the biological samples 23 before being cut is reduced.
The unidirectional screw 24 is rotationally installed in the working box 1, the unidirectional screw 24 is in threaded connection with the sliding block 18, a motor 25 is fixedly installed on the outer wall of one side of the working box 1, an output shaft of the motor 25 is fixedly connected with a rotating shaft of the unidirectional screw 24, and the unidirectional screw 24 is driven to start rotating through the output shaft of the motor 25, so that the sliding block 18 is driven to drive the sample carrying plate 21 to move, the laser cutting head 4 can continuously cut the biological sample 23, and the cutting efficiency of the device is improved.
It should be noted that, in the present utility model, the circuits, electronic components and modules are all related to the prior art, and those skilled in the art may implement the present utility model completely, and it is needless to say that the protection of the present utility model does not relate to improvement of software and methods.
The working principle of the automatic separation device for the laser cutting of the biological sample provided by the utility model is as follows:
the scheme is also provided with an electric control cabinet, the electric control cabinet is arranged on the equipment, when the electric control cabinet is used, each electric equipment can be started to operate respectively, the power connection mode of each electric equipment is the prior mature technology, is a well-known technology of the person in the field, and is not redundant;
When the laser cutting device is used, firstly, the box door is opened to place the sample carrying plate 21 on the sliding block 18, then the bidirectional screw rod 26 is driven to rotate by twisting the handle, and the clamping plate 20 is driven to move in the second sliding groove 19, so that the sample carrying plate 21 is clamped on the sliding block 18, the position deviation of the sample carrying plate 21 during moving is prevented, and the effect of laser cutting is influenced;
After the installation is finished, the box door is closed, the fan 5 is started at the moment, the air suction port 10 on the cavity 9 is used for sucking impurity gas in the box body through the air suction port 5, then the impurity gas is introduced into the purifying box 6 and is adsorbed and purified through the activated carbon plate 8, finally the impurity gas is discharged into the working box 1 again, the impurity gas removing and purifying effect is good, if the activated carbon plate 8 needs to be replaced, the activated carbon plate 8 in the first chute 7 is directly pulled and replaced, and the replacement mode is simple and convenient and easy to operate;
After the gas purification is finished, the electric guide rail 3 and the laser cutting head 4 are started, the laser cutting head 4 is driven to move through the electric guide rail 3, so that the biological sample 23 in the groove 22 is cut, the cutting surface is wider, the cutting effect is better, at the moment, the motor 25 is started, the unidirectional screw 24 is driven by the output shaft of the motor 25 to start rotating, so that the sliding block 18 is driven to drive the sample carrying plate 21 to move, the laser cutting head 4 can continuously cut the biological sample 23, and the cutting efficiency of the device is improved;
After cutting, start hydraulic stem 11, drive fixed plate 12 and mount pad 13 decline through the output pole of hydraulic stem 11 to make sampling needle 14 can take a sample biological sample 23 in recess 22, the sample operation is comparatively simple and convenient, easily height-adjusting, after the sample finishes, dismantle card strip 15 from draw-in groove 16 through pull bolt 17, thereby dismantle the change with mount pad 13 and sampling needle 14, it is comparatively simple and convenient to dismantle the change process.
Compared with the related art, the automatic separation device for the laser cutting of the biological sample has the following beneficial effects:
The utility model provides an automatic separating device for biological sample laser cutting, which drives a laser cutting head 4 to move through an electric guide rail 3, thereby cutting a biological sample 23 in a groove 22, having wider cutting surface and better cutting effect, leading an air suction port 10 on a cavity 9 to suck impurity gas in the cavity through a fan 5 in a gas impurity removing mechanism, then leading the gas into a purifying box 6, leading the gas to be adsorbed and purified through an active carbon plate 8, finally discharging the gas into a working box 1 again, leading the gas impurity removing and purifying effect to be better, directly leading the active carbon plate 8 in a first chute 7 to be pulled and replaced, leading the replacing mode to be simpler and easier to be operated, leading an output rod of a hydraulic rod 11 in a lifting sampling mechanism to drive a fixed plate 12 and a mounting seat 13 to descend, thereby leading a sampling needle 14 to sample the biological sample 23 in the groove 22, the sampling operation is comparatively simple and convenient, easily height-adjusting, dismantle card strip 15 from draw-in groove 16 through pull bolt 17, thereby dismantle mount pad 13 and sampling needle 14 and change, it is comparatively simple and convenient to dismantle the change process, drive bi-directional screw 26 rotation through torsion handle, drive cardboard 20 is at the second spout 19 internal motion, thereby establish carrying template 21 card on slider 18, prevent carrying template 21 position emergence skew when removing, the effect to laser cutting produces the influence, through set up biological sample 23 in recess 22, reduce biological sample 23 and receive the influence before being cut, drive unidirectional screw 24 through the output shaft of motor 25 and begin to rotate, thereby drive slider 18 drives carrying template 21 and move, make laser cutting head 4 can continuously cut biological sample 23, the cutting efficiency of device is improved.
It should be noted that, the device structure and the drawings of the present utility model mainly describe the principle of the present utility model, in terms of the technology of the design principle, the arrangement of the power mechanism, the power supply system, the control system, etc. of the device is not completely described, and on the premise that the person skilled in the art understands the principle of the present utility model, the specific details of the power mechanism, the power supply system and the control system can be clearly known, the control mode of the application file is automatically controlled by the controller, and the control circuit of the controller can be realized by simple programming of the person skilled in the art;
The standard parts used in the method can be purchased from the market, and can be customized according to the description of the specification and the drawings, the specific connection modes of the parts are conventional means such as mature bolts, rivets and welding in the prior art, the machines, the parts and the equipment are conventional models in the prior art, and the structures and the principles of the parts are all known by the skilled person through technical manuals or through conventional experimental methods.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations may be made therein without departing from the spirit and scope of the utility model as defined by the appended claims and their equivalents, and in other related technical fields, which are equally encompassed by the scope of the present utility model.
Claims (7)
1. A biological sample laser cutting autosegregation device, characterized by comprising:
a working box;
the supporting plate is fixedly arranged in the working box;
the electric guide rail is fixedly arranged at the bottom of the supporting plate;
The laser cutting head is fixedly arranged on the output block of the electric guide rail;
The gas impurity removing mechanism is arranged in the working box and used for removing impurities from gas;
And the lifting sampling mechanism is arranged in the working box and used for taking out samples.
2. The automatic biological sample laser cutting separation device according to claim 1, wherein the gas impurity removing mechanism comprises a fan, a purifying box, a plurality of first sliding grooves, a plurality of activated carbon plates, a cavity and a plurality of air inlets, wherein the fan is fixedly arranged at the top end of the supporting plate, the purifying box is fixedly arranged on the inner wall of the top of the working box, the air exhaust end of the fan is communicated with the purifying box, the plurality of first sliding grooves are formed in the purifying box, the plurality of activated carbon plates are respectively and correspondingly arranged in the plurality of first sliding grooves, the cavity is formed in the working box, the air inlet end of the fan is communicated with the cavity, and the plurality of air inlets are formed in the cavity.
3. The automatic separation device for laser cutting of biological samples according to claim 1, wherein the lifting sampling mechanism comprises a hydraulic rod, a fixing plate, a mounting seat and a plurality of sampling needles, the hydraulic rod is fixedly mounted on the inner wall of the top of the working box, the fixing plate is fixedly mounted on an output rod of the hydraulic rod, the mounting seat is arranged at the bottom of the fixing plate, and the sampling needles are all arranged on the mounting seat.
4. The automatic biological sample laser cutting and separating device according to claim 3, wherein two clamping strips are fixedly installed at the top of the installation seat, two clamping grooves are formed in the bottom of the fixing plate, the two clamping grooves are respectively and correspondingly arranged with the two clamping strips, a bolt is slidably installed on the fixing plate, and the bolt penetrates through the two clamping strips.
5. The automatic separation device for laser cutting of biological samples according to claim 1, wherein a sliding block is slidably installed on the inner wall of the bottom of the working box, a second sliding groove is formed in the sliding block, a bidirectional screw is rotatably installed in the second sliding groove, two clamping plates are installed on the bidirectional screw in a threaded mode, and a handle is fixedly installed at one end of the bidirectional screw.
6. The automatic separation device for laser cutting of biological samples according to claim 5, wherein a sample carrying plate is arranged on the sliding block, a plurality of grooves are formed in the sample carrying plate, and biological samples are arranged in the grooves.
7. The automatic separation device for laser cutting of biological samples according to claim 5, wherein the working box is rotatably provided with a one-way screw rod, the one-way screw rod is in threaded connection with the sliding block, a motor is fixedly arranged on the outer wall of one side of the working box, and an output shaft of the motor is fixedly connected with a rotating shaft of the one-way screw rod.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322682520.2U CN221064854U (en) | 2023-10-08 | 2023-10-08 | Automatic separating device for biological sample laser cutting |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322682520.2U CN221064854U (en) | 2023-10-08 | 2023-10-08 | Automatic separating device for biological sample laser cutting |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221064854U true CN221064854U (en) | 2024-06-04 |
Family
ID=91251919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322682520.2U Active CN221064854U (en) | 2023-10-08 | 2023-10-08 | Automatic separating device for biological sample laser cutting |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221064854U (en) |
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2023
- 2023-10-08 CN CN202322682520.2U patent/CN221064854U/en active Active
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