CN221038885U - Recombinant human collagen liquid preparation purification detection mechanism - Google Patents
Recombinant human collagen liquid preparation purification detection mechanism Download PDFInfo
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- CN221038885U CN221038885U CN202322522959.9U CN202322522959U CN221038885U CN 221038885 U CN221038885 U CN 221038885U CN 202322522959 U CN202322522959 U CN 202322522959U CN 221038885 U CN221038885 U CN 221038885U
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- fixed
- tray
- fixedly connected
- plate
- spring
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- 230000007246 mechanism Effects 0.000 title claims abstract description 43
- 239000007788 liquid Substances 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 238000000746 purification Methods 0.000 title claims abstract description 23
- 102000008186 Collagen Human genes 0.000 title claims abstract description 22
- 108010035532 Collagen Proteins 0.000 title claims abstract description 22
- 229920001436 collagen Polymers 0.000 title claims abstract description 22
- 238000001514 detection method Methods 0.000 title claims abstract description 22
- 238000007790 scraping Methods 0.000 claims abstract description 7
- 239000012530 fluid Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 description 4
- 239000000428 dust Substances 0.000 description 3
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to the field of purification detection mechanisms of human-source collagen liquid preparations, in particular to a purification detection mechanism of a recombinant human-source collagen liquid preparation, which comprises a chromatograph body, a tray, a scraping plate, a spring clamping mechanism and a clamping mechanism, wherein the tray is arranged above the chromatograph body, one end of the inside of the tray is provided with the scraping plate, the other end of the inside of the tray is provided with a liquid outlet, and the liquid outlet is fixedly connected with a liquid outlet conduit.
Description
Technical Field
The utility model relates to the field of purification detection mechanisms of human-source collagen liquid preparations, in particular to a purification detection mechanism of a recombinant human-source collagen liquid preparation.
Background
The purity of the recombinant human collagen liquid preparation is detected by adopting a high performance liquid chromatography, and the top of the existing high performance liquid chromatography for detecting the purity of the recombinant human collagen liquid preparation is usually provided with a tray or a groove, and a solvent bottle is placed through the tray or the groove.
The invention discloses a purification detection mechanism for a recombinant human collagen liquid preparation, which is disclosed in the Chinese patent document with the publication number of CN218393760U and the publication date of 20230131, and provides a purification detection mechanism for a recombinant human collagen liquid preparation, wherein the purification detection mechanism is positioned at the top of a whole chromatograph when a tray or a groove is provided, dust is easy to accumulate, a pouring solution is required to clean the tray or the groove in the tray and after dust is accumulated, the tray is more troublesome to move up and down, and more time and effort are required to be spent.
According to the scheme, the scraper is fixed only by extruding the tray through the screw rod, so that the stability of the scraper is fixed, the screw rod can be loosened in the long-time state, the scraper is moved, the purification work of the bulk preparation in the tray is troublesome, and the work efficiency is affected.
Therefore, the utility model provides a purification detection mechanism for a recombinant human collagen liquid preparation, which is used for solving the problems.
Disclosure of utility model
The utility model aims to provide a purification and detection mechanism for a recombinant human collagen liquid preparation, which aims to solve the problems in the background technology.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a recombinant human collagen liquid preparation purification detection mechanism, includes chromatograph body, tray, scraper blade, spring chucking mechanism and clamping mechanism, chromatograph body top is provided with the tray, the inside one end of tray is provided with the scraper blade, and the leakage fluid dram has been seted up to the other end, leakage fluid dram fixed connection flowing back pipe, supplementary right angle recess has been seted up to the tray side, supplementary fixed orifices has been seted up to supplementary right angle recess below, the one end of the inside fixed connection second spring of supplementary fixed orifices.
Preferably, the spring clamping mechanism comprises a fixed cylinder, a fixed long slat, a first auxiliary knob, a fixed plate, an auxiliary guide tube and a first spring, wherein the fixed long slat is fixedly connected with the outer side wall in the middle of the fixed cylinder, one end of the fixed cylinder is fixedly connected with the first auxiliary knob, one end of the fixed plate is fixedly connected with the auxiliary guide tube, the outer side of the auxiliary guide tube is provided with the first spring, one end of the first spring is fixedly connected with the side wall of the fixed plate, and the other end of the first spring is fixedly connected with the tray.
Preferably, the clamping mechanism comprises a push-pull plate, a through hole, a fixed block, a bolt, a second auxiliary knob, a rotating pin and a clamping fixed plate, wherein the push-pull plate is fixedly connected above the scraping plate, the through hole is formed in the push-pull plate, the side wall of one end of the tray is fixedly connected with the fixed block, the fixed block is in threaded connection with the bolt, one end of the bolt is fixedly connected with the second auxiliary knob, the other end of the bolt is fixedly connected with the rotating pin, and the clamping fixed plate is sleeved at the middle position of the rotating pin.
Preferably, the fixed cylinder is adapted to the auxiliary fixing hole, the fixed long strip plate can smoothly rotate ninety degrees in the auxiliary right-angle groove, the fixed long strip plate is provided with two through holes, the side wall of the tray is provided with a through hole corresponding to the auxiliary guide tube, and the auxiliary guide tube is adapted to the through hole provided by the fixed long strip plate.
Preferably, the spring clamping mechanisms are symmetrically distributed on two sides of the tray.
Preferably, the clamping mechanisms are symmetrically distributed on two sides of the push-pull plate, and the clamping fixing plate can rotate in the rotating pin.
Compared with the prior art, the utility model has the beneficial effects that:
According to the purification detection mechanism for the recombinant human collagen liquid preparation, disclosed by the utility model, for the method that a scraper in a tray is fixed after cleaning up during purification detection of a reagent, a method of extruding the tray by using a bolt is avoided, the bolt is fixed by using the cooperation of the spring clamping mechanism and the clamping mechanism, the bolt is required to be screwed by means of a corresponding tool when the original design is fixed by using the method of extruding the bolt initially, and in the long-term use process, the bolt can be loosened, so that the scraper in the tray can be moved, thereby influencing the work.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is an enlarged schematic view of a portion of the structural joint of FIG. 1 in accordance with the present utility model;
FIG. 3 is a schematic view of a spring connector according to the present utility model;
FIG. 4 is a schematic view of the tray structure of the present utility model;
FIG. 5 is an enlarged schematic view of a portion of the structural joint of FIG. 4 in accordance with the present utility model;
FIG. 6 is a schematic view of a semi-sectional structure of a scraper according to the present utility model.
In the figure: chromatograph body 1, drain pipe 2, tray 3, scraper blade 4, leakage fluid dram 5, supplementary right angle recess 6, supplementary fixed orifices 7, fixed cylinder 8, fixed lath 9, first supplementary knob 10, fixed plate 11, supplementary stand pipe 12, first spring 13, push-and-pull board 14, through-hole 15, fixed block 16, bolt 17, second supplementary knob 18, swivel pin 19, centre gripping fixed plate 20, second spring 21.
Detailed Description
The technical solutions in the embodiments of the present utility model will be clearly and completely described below. Embodiments of the present utility model are intended to be within the scope of the present utility model as defined by the appended claims.
Referring to fig. 1 to 6, the present utility model provides a technical solution: the utility model provides a recombinant human collagen liquid preparation purification detection mechanism, including chromatograph body 1, tray 3, scraper blade 4, spring chucking mechanism and clamping mechanism, chromatograph body 1 top is provided with tray 3, and the inside one end of tray 3 is provided with scraper blade 4, and the liquid outlet 5 has been seted up to the other end, and liquid outlet 5 fixed connection drain pipe 2, and auxiliary right angle recess 6 has been seted up to the side of tray 3, and auxiliary fixed orifices 7 have been seted up to auxiliary right angle recess 6 below, and the one end of auxiliary fixed orifices 7 inside fixed connection second spring 21; the spring clamping mechanism comprises a fixed cylinder 8, a fixed long slat 9, a first auxiliary knob 10, a fixed plate 11, an auxiliary guide tube 12 and a first spring 13, wherein the outer side wall in the middle of the fixed cylinder 8 is fixedly connected with the fixed long slat 9, one end of the fixed cylinder 8 is fixedly connected with the first auxiliary knob 10, one end of the fixed plate 11 is fixedly connected with the auxiliary guide tube 12, the first spring 13 is arranged outside the auxiliary guide tube 12, one end of the first spring 13 is fixedly connected with the side wall of the fixed plate 11, and the other end of the first spring 13 is fixedly connected with the tray 3; the clamping mechanism comprises a push-pull plate 14, a through hole 15, a fixed block 16, a bolt 17, a second auxiliary knob 18, a rotating pin 19 and a clamping fixed plate 20, wherein the push-pull plate 14 is fixedly connected above the scraping plate 4, the through hole 15 is formed in the push-pull plate 14, the side wall of one end of the tray 3 is fixedly connected with the fixed block 16, the fixed block 16 is in threaded connection with the bolt 17, one end of the bolt 17 is fixedly connected with the second auxiliary knob 18, the other end of the bolt 17 is fixedly connected with the rotating pin 19, and the clamping fixed plate 20 is sleeved at the middle position of the rotating pin 19; the fixed cylinder 8 is matched with the auxiliary fixed hole 7, the fixed long slat 9 can smoothly rotate ninety degrees in the auxiliary right-angle groove 6, the fixed long slat 9 is provided with two through holes, the side wall of the tray 3 is provided with a through hole corresponding to the auxiliary guide pipe 12, and the auxiliary guide pipe 12 is matched and corresponding to the through hole formed by the fixed long slat 9; the spring clamping mechanisms are symmetrically distributed on two sides of the tray 3; the clamping mechanisms are symmetrically distributed on two sides of the push-pull plate 14, and the clamping fixing plate 20 can rotate in the rotating pin 19.
According to the purification detection mechanism for the recombinant human collagen liquid preparation, after dust or dirt in the tray 3 is cleaned, the scraping plate 4 is pulled to be close to one end of the fixed block 16 through the push-pull plate 14, the fixed plate 11 is pulled outwards, the auxiliary guide tube 12 is separated from the tray 3, the action is kept, the fixed cylinder 8 is extruded into the auxiliary fixed hole 7, the second spring 21 is reached and then continues to be extruded until the fixed long plate 9 can smoothly rotate ninety degrees anticlockwise, the fixed plate 11 is loosened, the second spring 21 pushes the fixed cylinder 8 outwards due to elasticity, but is limited by the fixed long plate 9, the fixed long plate 9 is clamped with the auxiliary guide tube 12, the fixed long plate 9 is limited to move, at the moment, the scraping plate 4 is primarily fixed, the bolts 17 are rotated, one end of the fixed plate 20 is clamped through the rotary alignment through holes 15 until two cylinders at one end of the fixed plate 20 are all through the through holes 15, the operation is stopped, at the moment, the fixed plate 14 is fixedly connected with the push-pull plate 4, the whole operation steps are simple and rapid, the whole operation steps are improved, and no influence on the outside working period due to the fact that the fixing operation is completed under the condition of no help of a fixing tool is achieved.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides a recombinant human collagen liquid preparation purification detection mechanism which characterized in that: including chromatograph body (1), tray (3), scraper blade (4), spring chucking mechanism and clamping mechanism, chromatograph body (1) top is provided with tray (3), inside one end of tray (3) is provided with scraper blade (4), and leakage fluid dram (5) have been seted up to the other end, leakage fluid dram (5) fixed connection fluid dram (2), supplementary right angle recess (6) have been seted up to tray (3) side, supplementary fixed orifices (7) have been seted up to supplementary right angle recess (6) below, the one end of the inside fixed connection second spring (21) of supplementary fixed orifices (7).
2. The purification detection mechanism for a recombinant human collagen liquid preparation according to claim 1, wherein: the spring clamping mechanism comprises a fixed cylinder (8), a fixed long strip plate (9), a first auxiliary knob (10), a fixed plate (11), an auxiliary guide tube (12) and a first spring (13), wherein the fixed long strip plate (9) is fixedly connected with the middle outer side wall of the fixed cylinder (8), the first auxiliary knob (10) is fixedly connected with one end of the fixed cylinder (8), the auxiliary guide tube (12) is fixedly connected with one end of the fixed plate (11), the first spring (13) is arranged outside the auxiliary guide tube (12), one end of the first spring (13) is fixedly connected with the side wall of the fixed plate (11), and the other end of the first spring is fixedly connected with the tray (3).
3. The purification detection mechanism for a recombinant human collagen liquid preparation according to claim 1, wherein: the clamping mechanism comprises a push-pull plate (14), a through hole (15), a fixing block (16), a bolt (17), a second auxiliary knob (18), a rotating pin (19) and a clamping fixing plate (20), wherein the push-pull plate (14) is fixedly connected above the scraping plate (4), the through hole (15) is formed in the push-pull plate (14), the fixing block (16) is fixedly connected with one end side wall of the tray (3), the bolt (17) is connected with the thread of the fixing block (16), the second auxiliary knob (18) is fixedly connected with one end of the bolt (17), the rotating pin (19) is fixedly connected with the other end of the bolt, and the clamping fixing plate (20) is sleeved at the middle position of the rotating pin (19).
4. The purification and detection mechanism for a recombinant human collagen liquid preparation according to claim 2, wherein: the fixed cylinder (8) is matched with the auxiliary fixing hole (7), the fixed long slat (9) can smoothly rotate ninety degrees in the auxiliary right-angle groove (6), two through holes are formed in the fixed long slat (9), the through holes corresponding to the auxiliary guide pipes (12) are formed in the side wall of the tray (3), and the auxiliary guide pipes (12) are matched with the through holes formed in the fixed long slat (9).
5. The purification and detection mechanism for a recombinant human collagen liquid preparation according to claim 2, wherein: the spring clamping mechanisms are symmetrically distributed on two sides of the tray (3).
6. A recombinant human collagen liquid preparation purification detection mechanism according to claim 3, wherein: the clamping mechanisms are symmetrically distributed on two sides of the push-pull plate (14), and the clamping fixing plate (20) can rotate in the rotating pin (19).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322522959.9U CN221038885U (en) | 2023-09-18 | 2023-09-18 | Recombinant human collagen liquid preparation purification detection mechanism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322522959.9U CN221038885U (en) | 2023-09-18 | 2023-09-18 | Recombinant human collagen liquid preparation purification detection mechanism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221038885U true CN221038885U (en) | 2024-05-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322522959.9U Active CN221038885U (en) | 2023-09-18 | 2023-09-18 | Recombinant human collagen liquid preparation purification detection mechanism |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221038885U (en) |
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2023
- 2023-09-18 CN CN202322522959.9U patent/CN221038885U/en active Active
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