CN221028481U - Umbilical cord mesenchymal stem cell expansion device - Google Patents
Umbilical cord mesenchymal stem cell expansion device Download PDFInfo
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- CN221028481U CN221028481U CN202322712195.XU CN202322712195U CN221028481U CN 221028481 U CN221028481 U CN 221028481U CN 202322712195 U CN202322712195 U CN 202322712195U CN 221028481 U CN221028481 U CN 221028481U
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- groove
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- stem cell
- mesenchymal stem
- cell expansion
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- 210000002901 mesenchymal stem cell Anatomy 0.000 title claims abstract description 21
- 230000010261 cell growth Effects 0.000 title claims abstract description 19
- 210000003954 umbilical cord Anatomy 0.000 title claims description 13
- 238000003756 stirring Methods 0.000 claims abstract description 22
- 238000009434 installation Methods 0.000 claims description 4
- 239000001963 growth medium Substances 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 abstract description 18
- 230000000694 effects Effects 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000003321 amplification Effects 0.000 description 2
- 244000309464 bull Species 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 210000004748 cultured cell Anatomy 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model is suitable for the technical field of stem cell expansion, and provides an umbilical mesenchymal stem cell expansion device, which comprises a base, a culture bottle and a placing groove, wherein the placing groove is arranged in the top end of the base, the culture bottle is arranged in the placing groove, a stirring structure is arranged in the culture bottle, a temperature control structure is arranged at the bottom end of the base, clamping structures are arranged at two sides of the base, a control panel is arranged at the front end of the base, the temperature control structure comprises a mounting groove, a heater and a temperature sensor, the mounting groove is arranged in the bottom end of the base, the heater is arranged in the mounting groove, and the temperature sensor is arranged at one side of the placing groove.
Description
Technical Field
The utility model belongs to the technical field of stem cell expansion, and particularly relates to an umbilical cord mesenchymal stem cell expansion device.
Background
The umbilical cord mesenchymal stem cells refer to multifunctional stem cells existing in umbilical cord tissues of newborns, can be differentiated into various tissue cells, and have wide clinical application prospect 1. The human umbilical cord mesenchymal stem cells can be successfully amplified by using the inactivated umbilical cord serum culture system, the cultured cells have the basic characteristics of the mesenchymal stem cells, theoretical basis is provided for establishing a mesenchymal stem cell library and clinical application, a stem cell amplification device is used when the umbilical cord mesenchymal stem cells are amplified and cultured, and the traditional stem cell amplification device has some problems when in use;
when the conventional stem cell expansion device is used, stem cells are generally put into a culture solution to perform an expansion culture operation on the stem cells, but the temperature of the stem cells is inconvenient to control in the culture process, so that the culture effect is easily affected by the temperature difference in the culture process, and therefore, an umbilical cord mesenchymal stem cell expansion device is needed to solve the above problems.
Disclosure of utility model
The utility model provides an umbilical cord mesenchymal stem cell expansion device, which aims to solve the problem that the traditional stem cell expansion device is inconvenient to control the temperature inside a culture bottle during use.
The utility model discloses an umbilical mesenchymal stem cell expansion device, which comprises a base, a culture bottle and a placing groove, wherein the placing groove is arranged in the top end of the base, the culture bottle is arranged in the placing groove, a stirring structure is arranged in the culture bottle, a temperature control structure is arranged at the bottom end of the inside of the base, clamping structures are arranged at two sides of the base, a control panel is arranged at the front end of the base, the temperature control structure comprises a mounting groove, a heater and a temperature sensor, and the mounting groove is arranged in the bottom end of the base.
Preferably, a heater is arranged in the installation groove, and the temperature sensor is arranged on one side of the inside of the placement groove.
Preferably, the heaters are arranged in two groups, and the two groups of heaters are symmetrically distributed in the installation groove.
Preferably, the stirring structure comprises a micro motor, a connecting shaft and a stirring column, wherein the micro motor is arranged at the top end of the culture flask, the connecting shaft is arranged inside the culture flask, and the stirring column is arranged at the bottom end of the connecting shaft.
Preferably, the clamping structure comprises a rotating rod, a rotating groove and clamping plates, wherein the rotating groove is formed in two sides of the inside of the base, the rotating rod is arranged in the rotating groove, and the clamping plates are arranged on one side of the rotating rod.
Preferably, the outside of bull stick is provided with the external screw thread, the inboard of changeing the groove is provided with the internal screw thread, constitute threaded connection between bull stick and the changeing the groove.
Preferably, the two groups of clamping plates are symmetrically distributed on the inner side of the placing groove.
Compared with the prior art, the embodiment of the application has the following main beneficial effects:
Through the cooperation of heater and temperature sensor, can carry out a control to the temperature of the inside culture solution of blake bottle, make stem cell keep at suitable temperature all the time and carry out a culture to the effect is better when amplifying stem cell culture.
The micro motor and the stirring column are matched to drive the stirring column to stir the culture solution, so that the efficiency of the stem cells in absorbing the culture solution is higher, and the effect is better;
Through the cooperation with changeing the groove and using, can carry out a centre gripping to the blake bottle through the grip block, make the blake bottle more stable when using, the condition of slope can not appear easily to the effect of centre gripping has been improved.
Drawings
FIG. 1 is a schematic elevational cross-sectional view of the present utility model;
FIG. 2 is a schematic elevational view of the present utility model;
FIG. 3 is a schematic top view of the present utility model;
FIG. 4 is a schematic elevational view of the clamping structure of the present utility model;
In the figure: 1. a base; 2. a temperature control structure; 201. a mounting groove; 202. a heater; 203. a temperature sensor; 3. a culture bottle; 4. a stirring structure; 401. a micro motor; 402. a connecting shaft; 403. stirring the column; 5. a clamping structure; 501. a rotating rod; 502. a rotary groove; 503. a clamping plate; 6. a control panel; 7. and (5) placing a groove.
Detailed Description
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used in the description of the applications herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application; the terms "comprising" and "having" and any variations thereof in the description of the application and the claims and the description of the drawings above are intended to cover a non-exclusive inclusion. The terms first, second and the like in the description and in the claims or in the above-described figures, are used for distinguishing between different objects and not necessarily for describing a sequential or chronological order.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.
The embodiment of the utility model provides an umbilical mesenchymal stem cell expansion device, which comprises a base 1, a culture flask 3 and a placing groove 7, wherein the placing groove 7 is arranged in the top end of the base 1, the culture flask 3 is arranged in the placing groove 7, a stirring structure 4 is arranged in the culture flask 3, a temperature control structure 2 is arranged at the bottom end of the inside of the base 1, clamping structures 5 are arranged on two sides of the base 1, and a control panel 6 is arranged at the front end of the base 1;
Specifically, in the present embodiment: when stem cells are cultured and amplified, the stem cells are placed in the culture solution in the culture flask 3, then the culture flask 3 is clamped through the clamping structure 5, the temperature of the culture solution is controlled through the temperature control structure 2 after the clamping is finished, the stirring structure 4 is started to stir the culture solution after the temperature control is finished, the absorption of the stem cells is accelerated, and therefore the umbilical cord mesenchymal stem cells are amplified.
In a further preferred embodiment of the present utility model, as shown in FIGS. 1-4: the temperature control structure 2 comprises a mounting groove 201, a heater 202 and a temperature sensor 203, wherein the mounting groove 201 is arranged in the bottom end of the base 1, the heater 202 is arranged in the mounting groove 201, the temperature sensor 203 is arranged on one side of the inside of the placing groove 7, the heaters 202 are arranged in two groups, and the two groups of heaters 202 are symmetrically distributed in the mounting groove 201.
Specifically, when the culture flask 3 is placed in the placement tank 7, the heater 202 is started, the heater 202 generates heat after being started, then the heat is conducted to the interior of the culture flask 3, the culture solution is heated, the temperature is monitored by the temperature sensor 203, and the data is displayed on the control panel 6, so that the temperature control work is completed.
In a further preferred embodiment of the present utility model, as shown in FIGS. 1-4: the stirring structure 4 comprises a micro motor 401, a connecting shaft 402 and a stirring column 403, wherein the micro motor 401 is arranged at the top end of the culture flask 3, the connecting shaft 402 is arranged in the culture flask 3, and the stirring column 403 is arranged at the bottom end of the connecting shaft 402.
Specifically, when the micro motor 401 is started during heating, the micro motor 401 drives the stirring column 403 to rotate through the connecting shaft 402 after being started, so that the absorption effect of stem cells is accelerated by stirring the culture solution, and the effect of the stem cells during culturing is better.
In a further preferred embodiment of the present utility model, as shown in FIGS. 1-4: the clamping structure 5 comprises a rotating rod 501, rotating grooves 502 and clamping plates 503, wherein the rotating grooves 502 are formed in two sides of the inside of the base 1, the rotating rods 501 are arranged in the rotating grooves 502, the clamping plates 503 are arranged on one sides of the rotating rods 501, external threads are arranged on the outer sides of the rotating rods 501, internal threads are arranged on the inner sides of the rotating grooves 502, the rotating rods 501 and the rotating grooves 502 form threaded connection, the clamping plates 503 are provided with two groups, and the two groups of clamping plates 503 are symmetrically distributed on the inner sides of the placing grooves 7.
Specifically, in this embodiment, when the culture flask 3 is placed in the placement groove 7, the rotating rod 501 is rotated, and the clamping plate 503 is pushed to clamp the culture flask 3 along with the rotation between the rotating rod 501 and the rotating groove 502, so that the culture flask 3 is more stable in the placement groove 7, and the clamping work is completed.
It should be noted that, for simplicity of description, the foregoing embodiments are all illustrated as a series of acts, but it should be understood by those skilled in the art that the present utility model is not limited by the order of acts, as some steps may be performed in other order or concurrently in accordance with the present utility model. Further, those skilled in the art will also appreciate that the embodiments described in the specification are all preferred embodiments, and that the acts and modules referred to are not necessarily required for the present utility model.
In the several embodiments provided by the present application, it should be understood that the disclosed apparatus may be implemented in other manners. For example, the apparatus embodiments described above are merely illustrative, and such partitioning of the above-described elements may be implemented in other manners, e.g., multiple elements or components may be combined or integrated into another system, or some features may be omitted, or not performed. Alternatively, the coupling or communication connection shown or discussed as being between each other may be an indirect coupling or communication connection between devices or elements via some interfaces, which may be in the form of telecommunications or otherwise.
The units described above as separate components may or may not be physically separate, and components shown as units may or may not be physical units, may be located in one place, or may be distributed over a plurality of network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.
The above embodiments are only for illustrating the technical solution of the present utility model, and not for limiting the scope of the present utility model. It will be apparent that the described embodiments are merely some, but not all, embodiments of the utility model. Based on these embodiments, all other embodiments that may be obtained by one of ordinary skill in the art without inventive effort are within the scope of the utility model. Although the present utility model has been described in detail with reference to the above embodiments, those skilled in the art may still combine, add or delete features of the embodiments of the present utility model or make other adjustments according to circumstances without any conflict, so as to obtain different technical solutions without substantially departing from the spirit of the present utility model, which also falls within the scope of the present utility model.
Claims (7)
1. An umbilical cord mesenchymal stem cell expansion device, which is characterized in that: the culture medium comprises a base (1), a culture bottle (3) and a placing groove (7), wherein the placing groove (7) is formed in the top end of the base (1), and the culture bottle (3) is arranged in the placing groove (7);
The inside of the culture bottle (3) is provided with a stirring structure (4), and the bottom end of the inside of the base (1) is provided with a temperature control structure (2);
clamping structures (5) are arranged on two sides of the base (1), and a control panel (6) is arranged at the front end of the base (1);
the temperature control structure (2) comprises a mounting groove (201), a heater (202) and a temperature sensor (203), wherein the mounting groove (201) is arranged in the bottom end of the base (1).
2. An umbilical cord mesenchymal stem cell expansion apparatus as claimed in claim 1, wherein a heater (202) is provided inside the installation groove (201);
The temperature sensor (203) is arranged on one side of the inside of the placing groove (7).
3. An umbilical mesenchymal stem cell expansion apparatus as claimed in claim 1, wherein the heaters (202) are provided in two groups, and the two groups of heaters (202) are symmetrically distributed in the installation groove (201).
4. An umbilical mesenchymal stem cell expansion apparatus as claimed in claim 3 wherein the stirring structure (4) comprises a micro motor (401), a connecting shaft (402) and a stirring column (403), the micro motor (401) is disposed at the top end of the culture flask (3), the connecting shaft (402) is disposed in the culture flask (3), and the stirring column (403) is disposed at the bottom end of the connecting shaft (402).
5. The umbilical mesenchymal stem cell expansion device according to claim 1, wherein the clamping structure (5) comprises a rotating rod (501), a rotating groove (502) and clamping plates (503), the rotating groove (502) is formed in two sides of the inside of the base (1), the rotating rod (501) is arranged in the rotating groove (502), and the clamping plates (503) are arranged on one side of the rotating rod (501).
6. The umbilical mesenchymal stem cell expansion device according to claim 5, wherein an external thread is provided on the outer side of the rotating rod (501), an internal thread is provided on the inner side of the rotating groove (502), and a threaded connection is formed between the rotating rod (501) and the rotating groove (502).
7. An umbilical mesenchymal stem cell expansion apparatus as claimed in claim 5, wherein two groups of the clamping plates (503) are provided, and the two groups of the clamping plates (503) are symmetrically distributed inside the placement groove (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322712195.XU CN221028481U (en) | 2023-10-10 | 2023-10-10 | Umbilical cord mesenchymal stem cell expansion device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322712195.XU CN221028481U (en) | 2023-10-10 | 2023-10-10 | Umbilical cord mesenchymal stem cell expansion device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221028481U true CN221028481U (en) | 2024-05-28 |
Family
ID=91176653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322712195.XU Active CN221028481U (en) | 2023-10-10 | 2023-10-10 | Umbilical cord mesenchymal stem cell expansion device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221028481U (en) |
-
2023
- 2023-10-10 CN CN202322712195.XU patent/CN221028481U/en active Active
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