CN220989798U - Urine filter - Google Patents

Abstract

The present application provides a urine filtration device comprising: the first barrel body and the second barrel body are provided with a first opening end at one end, and the other end can be communicated with the atmosphere; the first barrel body and the second barrel body are provided with sliding grooves; the baffle plate and the filter screen can extend into the first barrel body or the second barrel body from the outer sides of the first barrel body and the second barrel body along the sliding grooves through the side walls of the baffle plate and the filter screen, and the baffle plate and the filter screen are respectively divided into two independent chambers; the two pistons are respectively matched with the inner walls of one side of the first opening end of the first barrel body and the inner walls of one side of the first opening end of the second barrel body. The device avoids a large number of manual operations, and the urine sample treatment efficiency is higher, simpler and quicker; the treatment of the urine sample is completed at the detected person, and the experimenter in subsequent detection does not need to contact with urine, so that the experimenter cannot feel the objection.

Description

Urine filter

Technical Field

The application relates to the technical field of medical equipment, in particular to a urine filtering device.

Background

In the prior art, the bladder cancer methylation detection sample is acquired by centrifuging urine through a centrifuge. Generally, after a urine sample of a person to be tested is obtained, the urine sample is transferred into a centrifuge tube, and after the urine sample is centrifuged by a centrifuge, the urine sample is layered, a straw is used to take out urine residues, and the urine residues are diluted by a diluent to prepare a sample for methylation detection. However, the preparation process of the sample for methylation detection is complicated; the urine treatment is unhygienic, the laboratory environment is easy to be polluted, and the objection of laboratory staff is easy to be caused; sample pretreatment efficiency is low.

Disclosure of utility model

In order to solve the problems in the prior art, the application provides a urine filtering device. The technical scheme of the application is as follows:

A urine filtration device comprising:

The first barrel body and the second barrel body are provided with a first opening end at one end, and the other end can be communicated with the atmosphere; the first barrel body and the second barrel body are provided with sliding grooves;

The baffle plate and the filter screen can extend into the first barrel body or the second barrel body from the outer sides of the first barrel body and the second barrel body along the sliding grooves through the side walls of the baffle plate and the filter screen, and the baffle plate and the filter screen are respectively divided into two independent chambers;

The two pistons are respectively matched with the inner walls of one side of the first opening end of the first barrel body and the inner walls of one side of the first opening end of the second barrel body.

Further, the other end of the first barrel body and/or the second barrel body is provided with a second opening end; the urine filtration device further comprises: the cover body is matched with the second opening end of the first barrel body and/or the second barrel body; and the cover body is provided with an air hole.

Further, the equivalent circle diameter of the air hole is smaller than 4mm.

Further, the baffle includes: a baffle body; the first sealing ring is arranged on the baffle body and is used for sealing the baffle body and the inner wall of the first barrel body or the second barrel body when the baffle is inserted into the chute; the first drawing part is arranged on the baffle body and is used for drawing the baffle body.

Further, the filter screen includes: a frame; the filter screen body is paved on the frame body; the second sealing ring is arranged on the frame body and used for sealing the inner walls of the frame body and the first barrel body or the second barrel body when the filter screen is inserted into the sliding groove; the second drawing part is arranged on the frame body and is used for drawing the frame body.

Further, the aperture of the filter screen body is 1-200 nm.

Further, the filter screen further comprises: the support body is arranged on the frame body and positioned at the bottom of the filter screen body, so as to be used for supporting the filter screen body.

Further, the support body is a load-bearing net.

Further, the piston includes: the piston body can be matched with the inner walls of the first opening ends of the first barrel body and the second barrel body; and one end of the piston rod is connected with the piston body.

Further, the urine filtration device further comprises: and a connecting member connecting the first tub 11 and the second tub 12.

Further, the urine filtration device further comprises: the handle is arranged on the first barrel body and/or the second barrel body.

The application provides the novel device for preparing the methylation detection sample, which can process the urine sample more simply and rapidly to prepare the methylation detection sample, and can collect and process the urine sample only by three steps of a sample adding and filtering step, a transposition step and a dilution step; moreover, the device ensures that the treatment of the urine sample is finished at the detected person, so that the environmental pollution of a laboratory is avoided, and the experimenter who performs subsequent detection does not need to contact with urine, so that the experimenter cannot feel objectionable; meanwhile, a large number of manual operations are avoided, and the device provided by the application has the advantage that the treatment efficiency of the urine sample is higher; the second barrel body, the corresponding sliding grooves and the baffle are arranged, so that the diluent can be well reserved in the second lower cavity before the urine sample is treated, and the urine sample can be conveniently treated in time after the urine sample is obtained; when the cover body with the air holes is arranged, the piston can be conveniently pushed and pulled, and the diluted methylation detection sample can be conveniently added and taken out from the urine sample; when the baffle plate with the first sealing ring is arranged, the diluent can be better preserved, and the diluted methylation detection sample is prevented from flowing back to the second lower chamber; when setting up the filter screen that has the second sealing washer, can guarantee that urine sample all can filter through the filter screen, guarantee the filter effect.

The foregoing description is only an overview of the technical solutions of the present application, to the extent that it can be implemented according to the content of the specification by those skilled in the art, and to make the above-mentioned and other objects, features and advantages of the present application more obvious, the following description is given by way of example of the present application.

Drawings

Fig. 1: a schematic structure of a urine filtering device;

Fig. 2: a cover body structure schematic diagram;

fig. 3: schematic cross-sectional structures of the first barrel body and the second barrel body;

Fig. 4: a baffle plate structure schematic diagram;

Fig. 5: a schematic diagram of the upper structure of the filter screen;

fig. 6: a lower structure schematic diagram of the filter screen;

fig. 7: the piston structure is schematically shown.

Reference numerals illustrate:

11. A first tub; 11-1, a first upper chamber; 11-2, a first lower chamber; 12. a second tub; 12-1, a second upper chamber; 12-2, a second lower chamber; 13. a first open end; 14. a chute; 15. a second open end; 16. a cover body; 16-1 air holes; 16-2, a bulge; 17. a handle; 18. a connecting piece;

20. a baffle; 21. a baffle body; 22. a first seal ring; 23. a first drawing part;

30. a filter screen; 31. a frame; 32. a filter screen body; 33. a second seal ring; 34. a second drawing part; 35. a support body;

40. A piston; 41. a piston body; 42. a piston rod.

Detailed Description

The following embodiments of the application are merely illustrative of specific embodiments for carrying out the application and are not to be construed as limiting the application. Any other changes, modifications, substitutions, combinations, and simplifications that do not depart from the spirit and principles of the application are intended to be equivalent arrangements which are within the scope of the application.

It should be understood by those skilled in the art that, in the disclosure of the present application, the terms "first," "second," "third," "fourth," "fifth," etc. are used merely to distinguish between different structures, and do not limit the number of specific structures, connection relationships, etc.; additionally, references to orientation or positional relationships of "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," etc., are based on the orientation or positional relationships shown in the drawings, which are merely for convenience of description and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore the above terminology is not to be construed as limiting the application.

This embodiment provides a urine filtration device, as shown in fig. 1, comprising:

A first tub 11 and a second tub 12, one ends of the first tub 11 and the second tub 12 being provided as a first open end 13, and the other ends being capable of communicating with the atmosphere; and the first barrel 11 and the second barrel 12 are provided with sliding grooves 14;

The baffle 20 and the filter screen 30 can extend into the first barrel body and the second barrel body from the outer sides of the first barrel body and the second barrel body along the chute 14 through the side walls of the baffle 20 and the filter screen 30, and divide the first barrel body and the second barrel body into two mutually independent chambers respectively;

And two pistons 40, wherein the two pistons 40 are respectively matched with the inner walls of the first opening end 13 side of the first barrel body 11 and the second barrel body 12.

When the urine filtering device of the application is used for filtering urine, the first opening ends 13 of the first barrel body 11 and the second barrel body 12 need to be downward; the filter screen 30 extends into the first barrel 11 through the chute 14 of the first barrel 11 to divide the first barrel 11 into a first upper chamber 11-1 and a first lower chamber 11-2; the baffle 20 extends into the second barrel body 12 through the chute 14 of the second barrel body 12 to divide the second barrel body 12 into a second upper chamber 12-1 and a second lower chamber 12-2; a piston 40 extends into the first lower chamber 11-2; the other piston 40 seals the first open end 13 of the second barrel 12 to store diluent in the second lower chamber 12-2.

Thereafter, urine filtration is performed using the urine filtration device of the present application, specifically comprising:

A sample addition and filtration step, comprising: adding a urine sample into the first upper chamber 11-1 and drawing down the piston 40 drawn into the first lower chamber 11-2 to draw the urine sample from the first upper chamber 11-1 into the first lower chamber 11-2, and trapping urine residues on the upper portion of the filter screen 30;

A transposition step, comprising: exchanging the position of the filter screen 30 and the baffle 20, and keeping the side of the filter screen 30 for intercepting urine residues upwards;

and a dilution step of pushing a piston 40 sealing the first opening end of the second barrel body 12 to press the dilution liquid into the second upper chamber 12-1 from the second lower chamber 12-2, and flushing the urine residues on the filter screen 30 by the dilution liquid and diluting the urine residues.

Regarding the shape of the first tub and the second tub, the present application is not particularly limited, and may be, for example, a column shape, a quadrangular prism table, or a rectangular parallelepiped, in this embodiment.

As for the materials of the first tub and the second tub, there is no particular limitation in the present application, and both the first tub and the second tub in the present embodiment are made of a polymer material.

The volumes of the first tub and the first upper chamber and the first lower chamber thereof, and the volumes of the second tub and the second upper chamber and the second lower chamber thereof are not particularly limited, and a person skilled in the art can specifically adjust and design according to the volume of the urine sample to be treated.

Therefore, it can be known that the application provides a new device for preparing a methylation detection sample, through which a urine sample can be processed more simply and rapidly to prepare the methylation detection sample, and the collection and the processing of the urine sample can be completed only by three steps; moreover, the device ensures that the treatment of the urine sample is finished at the detected person, so that the environmental pollution of a laboratory is avoided, and the experimenter who performs subsequent detection does not need to contact with urine, so that the experimenter cannot feel objectionable; meanwhile, the device of the application ensures that the treatment efficiency of the urine sample is higher because a large number of manual operations are avoided; the second barrel body, the corresponding sliding grooves and the baffle are arranged, so that the diluent can be well reserved in the second lower cavity before the urine sample is treated, and the urine sample can be conveniently treated in time after the urine sample is acquired.

In one embodiment, as shown in fig. 1 and 2, the other end of the first tub 11 and/or the second tub 12 is provided as a second open end 15; the urine filtration device further comprises: a cover 16, wherein the cover 16 is matched with the second opening end 15 of the first barrel 11 and/or the second barrel 12; and the cover 16 is provided with an air hole 16-1.

As for the material of the cover of the present application, there is no particular limitation in the present application, and the cover 16 in this embodiment is made of a polymer material.

In this embodiment, the cover 16 is provided for the first and second tanks 11 and 12, so that the urine sample can be conveniently added into the first upper chamber 11-1 and the diluted methylation detection sample can be taken out from the second upper chamber 12-1. At the same time, the vent hole 16-1 is provided so that the first upper chamber 11-1, the second upper chamber 12-1 are in communication with the atmosphere, thereby facilitating the push-pull of the piston 40.

Preferably, the equivalent circular diameter of the air hole is smaller than 4mm (such as 1mm, 2mm or 3 mm), so that the air hole can be communicated with the atmosphere while guaranteeing that liquid cannot flow out, and the air pressure balance in the first barrel body and the second barrel body is kept.

The equivalent circular diameter of the present application means the diameter of a circle having the same area.

In addition, as shown in fig. 1 and 2, a protrusion 16-2 may be provided on the cover 16, so that the cover 16 may be easily opened. Of course, a groove may be provided on the cover 16 to facilitate opening of the cover 16.

In one embodiment, as shown in fig. 4, the baffle 20 includes:

a baffle body 21;

A first seal ring 22, the first seal ring 22 is disposed on the baffle body 21, for sealing the baffle body 21 and the inner wall of the first tub 11 or the second tub 12 when the baffle 20 is inserted into the chute 14;

A first drawing portion 23 provided on the shutter body 21 for drawing the shutter body 21.

The present application is not particularly limited as to the location of the first sealing ring 22 on the barrier body 21, as long as it can seal the barrier 20 with the inner wall of the first tub 11 or the second tub 12, and is particularly disposed on the upper side, the lower side, and/or the side of the barrier body. The first seal ring 22 is disposed around the upper edge of the baffle body 21 in this embodiment (as shown in fig. 4).

Regarding the material of the baffle body of the present application, there is no particular limitation in the present application, and the baffle body in the present embodiment is made of a polymer material.

Regarding the first drawing portion 23, a drawing handle having a rectangular groove is provided on one side of the shutter body 21 in this embodiment.

In this embodiment, the baffle 20 is specifically provided, the baffle body 21 may be inserted into the chute 14 through the first drawing portion 23, and the first sealing ring 22 seals the inner wall of the baffle body 21 and the first barrel 11 or the second barrel 12, so as to divide the first barrel or the second barrel into two independent chambers.

In one embodiment, as shown in fig. 5 and 6, the filter screen 30 includes:

a frame 31;

a screen body 32, wherein the screen body 32 is paved on the frame 31; the filter body 32 in this embodiment is a filter;

A second sealing ring 33, wherein the second sealing ring 33 is arranged on the frame body and is used for sealing the frame body and the inner wall of the first barrel body 11 or the second barrel body 12 when the filter screen 30 is inserted into the sliding groove 14;

And a second drawing part 34 provided on the frame 31 for drawing the frame 31.

The position of the second seal ring 33 on the frame 31 is not particularly limited as long as it seals the frame 31 and the inner wall of the first tub 11 or the second tub, and is disposed, for example, on the upper side, the lower side, and/or the side surface of the frame. The second seal 33 in this embodiment is disposed around the upper (as shown in fig. 5) and lower (as shown in fig. 6) edges of the frame.

In this embodiment, a specific scheme of the filter screen 30 is provided, the frame body 31 can be inserted into the chute 14 through the second drawing portion 34, and the second sealing ring 33 seals the inner walls of the frame body 31 and the first barrel body 11 or the second barrel body 12, so that the first barrel body 11 or the second barrel body 12 is divided into two independent chambers.

Regarding the pore size of the screen body 32, one skilled in the art can modify the screen body pore size according to the diameter of the urine residue desired to be retained. The aperture of the filter screen body is properly selected, so that the diluted methylation detection sample prepared by the device can be ensured to be consistent with the diluted methylation detection sample prepared by centrifugation in the prior art. In the present application, the pore diameter of the filter screen body is preferably 1 to 200nm (specifically, 20nm, 40nm, 60nm, 80nm, 100nm, 120nm, 140nm, 160nm or 180 nm). In this example, a filter membrane having a pore size of 8nm was used to filter urine residues of a size required for a sample for methylation detection.

In the second drawing portion 34, a drawing handle having a rectangular groove is provided on one side of the frame 31 in this embodiment.

In one embodiment, as shown in fig. 5 and 6, the filter screen 30 further includes: the support body 35, the support body 35 is disposed on the frame 31 and located at the bottom of the filter screen body 32, so as to be used for supporting the filter screen body 32.

The supporting body 35 plays a role in lifting the filter screen body 32, so that the filter screen body 32 cannot be broken due to overlarge stress, and the filtering effect cannot be affected. The support 35 may be a mesh, such as the mesh-like load-bearing mesh shown in fig. 6.

In one embodiment, as shown in fig. 7, the piston 40 includes:

A piston body 41, wherein the piston body 41 can be matched with the inner walls of the first barrel 11 and the second barrel 12 at the side of the first opening end 13; in this embodiment, the piston body 41 is a rubber plug;

a piston rod 42, one end of the piston rod 42 is connected to the piston body 41.

The piston body 41 is matched with the inner wall of one side of the first opening end 13 of the first barrel body 11, so that the piston body 41 is conveniently driven to move downwards by pulling down the piston rod 42, and urine samples are conveniently sucked into the first lower chamber 11-2 from the first upper chamber 11-1, and urine residues are trapped through the upper part of the filter screen 30; the piston body 41 is matched with the inner wall of the side of the first opening end 13 of the second barrel body 12, and the piston rod 42 is conveniently pushed upwards to drive the piston body 41 to move upwards, so that diluent is conveniently pressed into the second upper chamber 12-1 from the second lower chamber 12-2, urine residues are diluted, and a methylation detection sample is obtained.

In one embodiment, as shown in fig. 1 and 3, the urine filtration device further comprises: a connecting member 18, wherein the connecting member 18 connects the first tub 11 and the second tub 12; in this embodiment, the connecting member 18 is a plurality of connecting posts.

The first tub 11 and the second tub 12 can be connected by a connection 18. Especially, when the connection strength of the connection member 18 is small enough to be broken by bare hands of a user to separate the first tub 11 and the second tub 12, the connection member 18 may be broken during the above-mentioned "transposition step" to separate the first tub 11 and the second tub 12, and at this time, the first tub 11 sealed with the treated urine may be directly thrown away.

In one embodiment, as shown in fig. 1 and 3, the urine filtration device further comprises: a handle 17, the handle 17 being provided on the first tub 11 and/or the second tub 12.

The handle 17 is provided to facilitate the handling of the device by personnel. Especially when the handle 17 is arranged along the length direction of the first barrel 11 and the second barrel 12 and distributed on the upper side and the lower side of the chute, if the handle is arranged into a reinforcing rib structure, the connection strength of the upper chamber and the lower chamber can be increased, so that the handle is not easy to deform, and the influence of the reduction of the structural strength caused by the arrangement of the chute is reduced.

Although the embodiments of the present application have been described above, the present application is not limited to the above-described specific embodiments and application fields, and the above-described specific embodiments are merely illustrative, and not restrictive. Those skilled in the art, having the benefit of this disclosure, may effect numerous forms of the application as described herein without departing from the scope of the application as claimed.

Claims (11)

1. A urine filtration device comprising:

The first barrel body and the second barrel body are provided with a first opening end at one end, and the other end can be communicated with the atmosphere; the first barrel body and the second barrel body are provided with sliding grooves;

The baffle plate and the filter screen can extend into the first barrel body or the second barrel body from the outer sides of the first barrel body and the second barrel body along the sliding grooves through the side walls of the baffle plate and the filter screen, and the baffle plate and the filter screen are respectively divided into two independent chambers;

The two pistons are respectively matched with the inner walls of one side of the first opening end of the first barrel body and the inner walls of one side of the first opening end of the second barrel body.

2. The urine filter device of claim 1,

The other end of the first barrel body and/or the second barrel body is/are provided with a second opening end;

The urine filtration device further comprises:

The cover body is matched with the second opening end of the first barrel body and/or the second barrel body; and the cover body is provided with an air hole.

3. The urine filter device of claim 2,

The equivalent circle diameter of the air hole is smaller than 4mm.

4. The urine filter device of claim 1,

The baffle includes:

A baffle body;

The first sealing ring is arranged on the baffle body and is used for sealing the baffle body and the inner wall of the first barrel body or the second barrel body when the baffle is inserted into the chute;

The first drawing part is arranged on the baffle body and is used for drawing the baffle body.

5. The urine filter device of claim 1,

The filter screen includes:

A frame;

the filter screen body is paved on the frame body;

The second sealing ring is arranged on the frame body and used for sealing the inner walls of the frame body and the first barrel body or the second barrel body when the filter screen is inserted into the sliding groove;

the second drawing part is arranged on the frame body and is used for drawing the frame body.

6. The urine filter device of claim 5,

The aperture of the filter screen body is 1-200 nm.

7. The urine filter device of claim 5,

The filter screen further comprises:

The support body is arranged on the frame body and positioned at the bottom of the filter screen body, so as to be used for supporting the filter screen body.

8. The urine filter device of claim 7,

The support body is a bearing net.

9. The urine filter device of claim 1,

The piston includes:

The piston body can be matched with the inner walls of the first opening ends of the first barrel body and the second barrel body;

And one end of the piston rod is connected with the piston body.

10. The urine filter device of claim 1,

The urine filtration device further comprises:

The connecting piece is connected with the first barrel body and the second barrel body.

11. The urine filter device of claim 1,

The urine filtration device further comprises:

the handle is arranged on the first barrel body and/or the second barrel body.