CN220989797U - Impurity removing equipment for crude heparin sodium - Google Patents
Impurity removing equipment for crude heparin sodium Download PDFInfo
- Publication number
- CN220989797U CN220989797U CN202322704018.7U CN202322704018U CN220989797U CN 220989797 U CN220989797 U CN 220989797U CN 202322704018 U CN202322704018 U CN 202322704018U CN 220989797 U CN220989797 U CN 220989797U
- Authority
- CN
- China
- Prior art keywords
- heparin sodium
- crude heparin
- box body
- abutting
- impurity removal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 229920000669 heparin Polymers 0.000 title claims abstract description 48
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 title claims abstract description 46
- 229960001008 heparin sodium Drugs 0.000 title claims abstract description 46
- 239000012535 impurity Substances 0.000 title claims abstract description 30
- 238000001914 filtration Methods 0.000 claims abstract description 14
- 230000000149 penetrating effect Effects 0.000 claims abstract description 8
- 239000000463 material Substances 0.000 claims abstract description 4
- 238000005057 refrigeration Methods 0.000 claims description 23
- 230000005540 biological transmission Effects 0.000 claims description 4
- 238000003756 stirring Methods 0.000 abstract description 10
- 230000007246 mechanism Effects 0.000 abstract description 8
- 238000002347 injection Methods 0.000 abstract description 3
- 239000007924 injection Substances 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 23
- 238000001816 cooling Methods 0.000 description 6
- 239000013049 sediment Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 239000011435 rock Substances 0.000 description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 210000004347 intestinal mucosa Anatomy 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- -1 edulcoration seat 1 Chemical compound 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/10—Process efficiency
Landscapes
- Filtration Of Liquid (AREA)
Abstract
The utility model discloses impurity removing equipment for crude heparin sodium, which comprises an impurity removing seat, wherein the top of the impurity removing seat is provided with a filtering box body, the top end of the filtering box body is fixedly connected with a material injection pipe in a penetrating way, the bottom end of the filtering box body is fixedly provided with a plurality of fixing columns, one ends of the fixing columns are respectively provided with a reset spring, the middle part of the bottom end of the filtering box body is connected with a hose in a penetrating way, one ends of the plurality of reset springs are provided with a refrigerating box body, one side of the top end of the impurity removing seat is fixedly provided with a supporting plate, and a stirring mechanism and a filter screen are arranged in the filtering box body.
Description
Technical Field
The utility model relates to the technical field of crude heparin sodium impurity removal, in particular to impurity removal equipment for crude heparin sodium.
Background
Heparin sodium is widely existing in liver, lung and intestinal mucosa of mammals and is combined with proteins to form a complex, while crude heparin sodium is small intestinal mucosa of healthy live pigs extracted from heparin raw materials, and the heparin sodium can not be directly used due to the fact that the heparin sodium contains a large amount of impurity proteins, microorganisms and other impurities, so that impurity removal equipment is usually needed for removing impurities from the crude heparin sodium, and the purpose of the heparin sodium solution is to obtain crude heparin sodium solution with better quality.
The patent with publication number CN217188965U discloses a crude heparin sodium impurity removing device, which comprises a device base, the device base is including discharge mechanism, stirring sediment device and feeding mechanism, device base top fixedly connected with stirring sediment device, and stirring sediment device below fixedly connected with discharge mechanism, stirring sediment device back fixedly connected with feeding mechanism.
In the technology, the surface of the stirring tank can be rapidly cooled through the refrigerating device below the stirring tank, synchronous cooling of the crude heparin sodium solution is realized while stirring, however, the contact area between the crude heparin sodium solution and the refrigerating device is not comprehensive enough, the crude heparin sodium solution in the bottom range in the equipment can be mutually contacted with the refrigerating device and cooled, and the refrigerating speed of the crude heparin sodium solution at the top is slower, so that the technology is innovated.
Disclosure of utility model
The utility model aims to provide impurity removing equipment for crude heparin sodium, which aims to solve the problem that crude heparin sodium solution in the bottom range of the equipment provided in the background art can be contacted with a refrigerating device and cooled, and the refrigerating speed of the crude heparin sodium solution at the top is relatively slow.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a edulcoration equipment of crude heparin sodium, includes the edulcoration seat, the top of edulcoration seat is provided with the filter tank body, the top fixedly threaded connection of filter tank body has the injecting pipe, the bottom fixed mounting of filter tank body has a plurality of fixed columns, and is a plurality of the one end of fixed column all is provided with reset spring, the middle part of filter tank body bottom is threaded connection has the hose, and is a plurality of reset spring's one end is provided with the refrigeration box body, one side fixedly mounted on edulcoration seat top has the backup pad, one side of backup pad is provided with servo motor, servo motor's output shaft transmission is connected with the dwang, the both sides of refrigeration box body all are provided with the fixed block.
As a preferable technical scheme of the utility model, one side of the refrigeration box body is fixedly connected with a diversion pipe in a penetrating way, and one end of the hose is connected with the top end of the refrigeration box body in a penetrating way.
As a preferable technical scheme of the utility model, the top ends of the two fixing blocks are fixedly connected with auxiliary rods in a penetrating way, and one end part of the rotating rod is fixedly sleeved with two cam blocks.
As a preferable technical scheme of the utility model, the bottoms of the two auxiliary rods are respectively provided with a collision block, and the two cam blocks are respectively positioned at the bottoms of the two collision blocks.
As a preferable technical scheme of the utility model, one ends of the two auxiliary rods are fixedly provided with the abutting rods, and the top ends of the two abutting blocks are fixedly connected with one ends of the two abutting rods respectively.
As a preferable technical scheme of the utility model, the two abutting rods are arranged correspondingly, and the diameters of the two auxiliary rods are larger than those of the two abutting rods.
As a preferable technical scheme of the utility model, the positions of two adjacent fixed columns are corresponding.
Compared with the prior art, the utility model has the beneficial effects that:
According to the impurity removing equipment for the crude heparin sodium, the fixed column, the reset spring, the hose, the abutting blocks, the servo motor, the auxiliary rod, the rotating rod and the cam blocks are arranged, the stirring mechanism and the filter screen are arranged in the filter box body, particle impurities in the crude heparin sodium solution can be filtered in advance, the filtered crude heparin sodium solution can be conveyed into the refrigerating box body through the hose to be cooled, after the servo motor is started, the two cam blocks synchronously rotate, in the rotating process, the protruding parts on the surface of the cam blocks can exert upward force on the bottoms of the abutting blocks, so that the force is continuously transmitted to the refrigerating box body, the height of the refrigerating box body is gradually increased, the reset spring is stressed to be compressed, deformed and rocked, and the refrigerating box body is driven to rock after the refrigerating box body is lifted, so that the crude heparin sodium solution in the filter box body is continuously rocked, and the cooling efficiency of the crude heparin sodium solution is improved.
Drawings
FIG. 1 is a schematic elevational view of the present utility model;
FIG. 2 is a schematic partial elevation view of the present utility model;
FIG. 3 is a schematic diagram of a partial side view of the present utility model;
fig. 4 is a partial bottom view of the present utility model.
In the figure: 1. a impurity removing seat; 2. a filter box; 3. a material injection pipe; 4. fixing the column; 5. a return spring; 6. a hose; 7. a refrigeration box body; 8. a flow guiding pipe; 9. a support plate; 10. a servo motor; 11. a rotating lever; 12. a cam block; 13. a fixed block; 14. an auxiliary rod; 15. a collision block; 16. the rod is abutted.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-4, the utility model provides a technical scheme of impurity removal equipment for crude heparin sodium, which comprises the following steps:
As shown in fig. 1-4, a edulcoration equipment of crude heparin sodium, including edulcoration seat 1, the top of edulcoration seat 1 is provided with filtration box 2, the top fixed interlude of filtration box 2 is connected with filling pipe 3, the bottom fixed mounting of filtration box 2 has a plurality of fixed columns 4, the one end of a plurality of fixed columns 4 all is provided with reset spring 5, the middle part interlude of filtration box 2 bottom is connected with hose 6, the one end of a plurality of reset springs 5 is provided with refrigeration box 7, one side fixed mounting on edulcoration seat 1 top has backup pad 9, one side of backup pad 9 is provided with servo motor 10, the output shaft transmission of servo motor 10 is connected with dwang 11, the both sides of refrigeration box 7 all are provided with fixed block 13, the equal fixed interlude in top of two fixed blocks 13 is connected with auxiliary rod 14, the fixed cover in one end of dwang 11 is equipped with two cam blocks 12, the equal fixed mounting of one end of two auxiliary rod 14 is contradicted rod 16, the top of two conflict blocks 15 respectively with the one end fixed connection of two rod 16, the crude heparin sodium solution after the filtration can be through 6 guide block 7, the inside of hose 7 is carried out to the refrigeration box 7, thereby can continue to the high degree of rotation to the refrigeration box 7, the refrigeration box is carried out to the cam 7, the high side of the refrigeration box is carried out, and the refrigeration box is rotated and can be carried out, the high and the degree is carried out, and the process is continuously.
Working principle: the crude heparin sodium is a small intestine mucosa of a healthy pig extracted from heparin raw materials, and can not be directly used because of containing a large amount of impurity proteins, microorganisms and other impurities, so that impurity removal equipment is usually needed to remove impurities from the crude heparin sodium, therefore, workers need to sequentially pour the crude heparin sodium solution into the filter box body 2 through the injection pipe 3, a stirring mechanism and a filter screen are arranged in the filter box body 2, the granular impurities in the crude heparin sodium solution can be filtered in advance, the filtered crude heparin sodium solution can be guided into the refrigeration box body 7 through the hose 6 for cooling, the crude heparin sodium solution gradually precipitates after the temperature is reduced, thereby realizing rapid cooling impurity removal, the hose 6 is made of rubber materials, the surface is softer, and therefore the hose 6 can continuously shake when bearing pressure, the working personnel can start the servo motor 10, the cooling mechanism is arranged in the refrigeration box 7, the temperature can be gradually reduced, so that crude heparin sodium solution can be cooled, after the servo motor 10 is started, the rotating rod 11 which is in transmission connection with the output shaft of the servo motor is driven to rotate, the two cam blocks 12 fixedly sleeved at one end part of the servo motor are driven to rotate, the two cam blocks 12 synchronously rotate, in the rotating process, the convex parts on the surfaces of the cam blocks 12 can apply upward force to the bottoms of the abutting blocks 15, so that the force is continuously transmitted to the refrigeration box 7, the height of the refrigeration box 7 can be gradually increased, the restoring spring 5 can be compressed, deformed and rocked, the refrigeration box 7 can be driven to rock after the refrigeration box 7 is lifted, so that the crude heparin sodium solution in the refrigeration box continuously rocks, the contact area of the crude heparin sodium solution and the temperature is increased, the solution is cooled more comprehensively, and the cooling efficiency of the crude heparin sodium solution is improved.
In the description of the present utility model, it should be understood that the orientation or positional relationship indicated is based on the orientation or positional relationship shown in the drawings, and is merely for convenience in describing the present utility model and simplifying the description, and does not indicate or imply that the apparatus or element referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model.
In the present utility model, unless explicitly specified and defined otherwise, for example, it may be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intermediaries, or in communication with each other or in interaction with each other, unless explicitly defined otherwise, the meaning of the terms described above in this application will be understood by those of ordinary skill in the art in view of the specific circumstances.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. The utility model provides a edulcoration equipment of crude heparin sodium, includes edulcoration seat (1), its characterized in that: the top of edulcoration seat (1) is provided with filtration box (2), the top fixedly threaded connection of filtration box (2) has notes material pipe (3), the bottom fixed mounting of filtration box (2) has a plurality of fixed columns (4), and is a plurality of the one end of fixed column (4) all is provided with reset spring (5), the middle part of filtration box (2) bottom is threaded connection has hose (6), and is a plurality of the one end of reset spring (5) is provided with refrigeration box (7), one side fixed mounting on edulcoration seat (1) top has backup pad (9), one side of backup pad (9) is provided with servo motor (10), the output shaft transmission of servo motor (10) is connected with dwang (11), the both sides of refrigeration box (7) all are provided with fixed block (13).
2. The crude heparin sodium impurity removal device of claim 1, wherein: one side of the refrigeration box body (7) is fixedly connected with a guide pipe (8) in a penetrating way, and one end of the hose (6) is connected with the top end of the refrigeration box body (7) in a penetrating way.
3. The crude heparin sodium impurity removal device of claim 1, wherein: the top ends of the two fixed blocks (13) are fixedly connected with auxiliary rods (14) in a penetrating and inserting mode, and one end portion of the rotating rod (11) is fixedly sleeved with two cam blocks (12).
4. A crude heparin sodium impurity removal device according to claim 3, characterized in that: the bottoms of the two auxiliary rods (14) are provided with abutting blocks (15), and the two cam blocks (12) are respectively positioned at the bottoms of the two abutting blocks (15).
5. The impurity removal device for crude heparin sodium of claim 4, wherein: one end of each auxiliary rod (14) is fixedly provided with a corresponding abutting rod (16), and the top ends of the two abutting blocks (15) are fixedly connected with one ends of the two abutting rods (16) respectively.
6. The crude heparin sodium impurity removal device of claim 5, wherein: the two abutting rods (16) are arranged correspondingly, and the diameters of the two auxiliary rods (14) are larger than the diameters of the two abutting rods (16).
7. The crude heparin sodium impurity removal device of claim 1, wherein: the positions of the two adjacent fixed columns (4) are corresponding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322704018.7U CN220989797U (en) | 2023-10-10 | 2023-10-10 | Impurity removing equipment for crude heparin sodium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322704018.7U CN220989797U (en) | 2023-10-10 | 2023-10-10 | Impurity removing equipment for crude heparin sodium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220989797U true CN220989797U (en) | 2024-05-24 |
Family
ID=91089457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322704018.7U Active CN220989797U (en) | 2023-10-10 | 2023-10-10 | Impurity removing equipment for crude heparin sodium |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220989797U (en) |
-
2023
- 2023-10-10 CN CN202322704018.7U patent/CN220989797U/en active Active
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |