CN220905958U

CN220905958U - Precooling monitoring device for sample

Info

Publication number: CN220905958U
Application number: CN202322267146.XU
Authority: CN
Inventors: 杨荣洲; 彭兴; 李琰
Original assignee: Metanotitia Inc
Current assignee: Metanotitia Inc
Priority date: 2023-08-22
Filing date: 2023-08-22
Publication date: 2024-05-07
Anticipated expiration: 2033-08-22

Abstract

The application relates to a pre-cooling monitoring device for a sample, which comprises: the box body is used for placing a sample; the temperature sensor is positioned in the box body and is used for measuring the temperature in the box body; and the temperature display is arranged outside the box body and used for displaying the temperature measured by the temperature sensor. According to the sample pre-cooling monitoring device provided by the application, the current temperature inside the box body can be monitored in real time through the temperature sensor and the temperature display, so that an operator can conveniently know whether the pre-cooling of the box body reaches the preset condition or not and whether the sample is at a proper temperature or not in the process of operating the sample in the box body, and the invisible sample damage is avoided.

Description

Precooling monitoring device for sample

Technical Field

The application relates to the field of sample cryopreservation, in particular to a pre-cooling monitoring device for samples.

Background

At present, all laboratories involving cryopreservation of samples are faced with temporary transfer and handling problems of samples. A common approach is to place the sample temporarily using an incubator or foam box filled with dry ice, liquid nitrogen, etc.

However, this common treatment method lacks temperature monitoring, so that it is difficult to evaluate the actual temperature of the position where the sample is located, and the invisible sample is easily damaged. Moreover, the common incubator is generally designed and applied to about 0-8 ℃ and is not suitable for high heat insulation performance required by laboratories, in addition, materials of the incubator, the foam box and the like are simple, and a rack is not specially designed for an experimental sample container, so that a sample is placed in the box body in disorder.

Disclosure of utility model

In order to solve the above problems in the prior art, the present application provides a pre-cooling monitoring device for a sample, including:

the box body is used for placing a sample;

The temperature sensor is positioned in the box body and is used for measuring the temperature in the box body; and

And the temperature display is arranged outside the box body and used for displaying the temperature measured by the temperature sensor.

According to some embodiments, the pre-cooling monitoring device further comprises:

the storage rack is positioned in the box body and used for placing the sample; and

The fixing frame is positioned at the bottom of the box body and used for fixing the commodity shelf.

According to some embodiments, the temperature sensor is located at an opening of the case.

According to some embodiments, the temperature sensor comprises a first temperature sensor and a second temperature sensor, wherein the first temperature sensor is located at the opening of the box body, and the second temperature sensor is located at the bottom of the inner side of the box body.

According to some embodiments, one or more temperature sensors are further included between the first temperature sensor and the second temperature sensor, the one or more temperature sensors being for measuring a temperature between an opening of the case and an inside bottom of the case.

The division plate is positioned between the fixing frames and used for dividing the low-temperature consumable materials from the storage rack.

According to some embodiments, the temperature display is mounted around the outside of the case.

According to some embodiments, the material of the box comprises a high performance insulating material.

According to some embodiments, the structure of the holder matches the structure of the rack, which matches the structure of the sample container to be placed.

According to some embodiments, the opening of the box body is provided with a cover.

According to the sample pre-cooling monitoring device provided by the application, on one hand, the current temperature inside the box body can be monitored in real time through the temperature sensor and the temperature display, so that an operator can know whether the pre-cooling of the box body reaches the preset condition or not and whether the sample is at a proper temperature or not in the process of operating the sample in the box body, and the invisible sample damage is avoided. On the other hand, a storage rack is arranged in the box body, so that samples can be conveniently transferred, stored and operated. In addition, the box body adopts high-density polyurethane materials or high-performance heat preservation materials such as vacuum heat preservation, can effectively isolate the temperature in the box body from the outside, has reduced the loss of low temperature consumptive material in the box body.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for the description of the embodiments will be briefly described below, and it will be apparent that the drawings in the following description are only some embodiments of the present application, and that other drawings can be obtained according to these drawings by those skilled in the art without departing from the scope of the claimed application.

Fig. 1 is a front view of a sample pre-chill monitoring apparatus according to an embodiment of the present application.

Fig. 2 is a top view of a sample pre-chill monitoring apparatus according to an embodiment of the present application.

Fig. 3 is a schematic view of a rack in a pre-cooling monitoring device for samples.

Fig. 4 is a schematic view of a holder in a pre-cooling monitoring device for a sample.

Fig. 5 is a schematic view of a divider plate in a pre-cooling monitoring device for a sample.

Reference numerals: 1 box, 2 supporter, 3 division board, 11 first temperature sensor, 12 second temperature sensor, 13 temperature display, 14 lids, 15 handles, 16 mount.

Detailed Description

The following description of the embodiments of the present application will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are some, but not all embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.

Fig. 1 is a front view of a sample pre-chill monitoring apparatus according to an embodiment of the present application. Fig. 2 is a top view of a sample pre-chill monitoring apparatus according to an embodiment of the present application. As shown in fig. 1 and 2, the apparatus includes a case 1, a temperature sensor, and a temperature display 13. Wherein, box 1 is used for placing the sample, and temperature sensor is located inside box 1 for the inside temperature of measurement box 1, temperature display 13 arranges in the box 1 is outside, is used for showing temperature sensor measuring temperature.

According to some embodiments, the case 1 may be any structure suitable for storing a sample, for example, a cuboid, a cylinder, or the like. The size of the case 1 may be selected from various specifications, for example, may vary from 32L to 85L. The opening of the case 1 may have a cover 14 or may have no cover 14. With the cover 14, pre-cooling of the case 1 before storing the sample is facilitated, facilitating a faster drop in temperature to the set temperature. After the cover is opened, any proper angle (135 degrees for example) is maintained with the opening of the box body 1, so that the operations of storing and taking out the sample are convenient.

According to some embodiments, the case 1 may be any thermal insulation material. In the present application, the case 1 may employ a high-performance thermal insulation material such as a high-density polyurethane material or a vacuum thermal insulation material. The common incubator in the prior art is only suitable for a household environment, for example, about minus 0-8 ℃, but the requirement of a laboratory on the heat insulation performance is far greater than that of the household environment, for example, the temperature of liquid nitrogen is minus 196 ℃, the common incubator is easy to damage, and even if the incubator is not damaged, the heat insulation effect is poor, the consumption speed of liquid nitrogen and the like is overlarge, and the extra cost is caused. The box body 1 made of the high-performance heat-insulating material can isolate the internal and external temperatures of the box body 1 more effectively, and reduces the loss of low-temperature consumables such as dry ice, liquid nitrogen and the like in the box body 1.

According to some embodiments, one or more handles 15 or recessed areas may be provided on the outside of the case 1 to facilitate movement of the case 1 by an operator.

According to some embodiments, the temperature display 13 may be mounted around the outside of the case 1. For example, the temperature display 13 may be adhered to the outside of the case 1 or embedded in the outside of the case 1, and the temperature display 13 is not shielded by the case, so that an operator can observe the temperature conveniently.

According to some embodiments, for the temperature sensor, any sensor that can be used to measure temperature may be used, as long as its measurement range is satisfactory. For example, a non-contact type temperature measuring instrument can be adopted, and a radiation temperature measuring method is adopted. Such a sensor can be used to measure the surface temperature of moving objects, small targets and objects with small heat capacity or rapid temperature change (transients), as well as to measure the temperature distribution of a temperature field.

According to some embodiments, the temperature sensor may be located at any position inside the tank 1, for example at the bottom inside the tank 1, at the opening of the tank 1, or between the bottom and the opening.

According to some embodiments, a temperature sensor may be placed at the opening of the case 1. Generally, low-temperature consumables such as dry ice, liquid nitrogen and the like are stored at the bottom of the box body 1, the temperature is lowest, the opening is in contact with the outside air, and the temperature is relatively highest. When the temperature at the opening is not higher than the preset temperature, the temperature of the sample is not higher than the preset temperature under the condition that the sample is stored in the box body 1, so that the sample can be ensured not to be damaged due to high temperature.

According to some embodiments, the number of temperature sensors includes two, including a first temperature sensor 11 and a second temperature sensor 12, wherein the first temperature sensor 11 is located at the opening of the case 1, and the second temperature sensor 12 is located at the bottom of the inside of the case 1. Thus, not only the temperature at the opening of the box body 1 can be monitored, but also the temperature at the bottom of the inner side of the box body 1 can be monitored. Through the temperature of the inboard bottom of monitoring box 1, can know whether the low temperature consumptive material is too much, be convenient for when consuming too much suggestion operating personnel in time supplements the low temperature consumptive material.

According to some embodiments, one or more temperature sensors may also be placed between the first temperature sensor 11 and the second temperature sensor 12 for measuring the temperature between the opening of the tank 1 and the bottom inside the tank 1. The sample is usually located between the opening of the case 1 and the bottom of the inner side, and by providing more temperature sensors, the temperature of the position where the sample is located can be reflected more accurately and directly.

Equipment such as incubator among the prior art is comparatively simple, and inside does not carry out special design to experimental sample container, like EP pipe (centrifuging tube), leads to the sample to put chaotic in the incubator, also can face with the incubator discomfort when putting into interim operation panel, need extra precooling scheduling problem.

In view of the above problems, the present application provides a rack 2 adapted to a case 1 and a fixing frame 16 mounted on the bottom of the case 1, wherein the fixing frame 16 is fixed on the bottom of the case 1 near four corners of the case 1, as shown in fig. 3 and 4, for fixing the rack 2 and a partition plate 3 placed in the case 1. The structure of the fixing frame 16 is matched with the structures of the shelf 2 and the partition plate 3. The rack 2 is located inside the box 1 and is used for placing samples. And, the structure of supporter 2 matches with the structure of the sample container that waits to place, can be to the common sample container design supporter 2's in laboratory structure. For example, the sample container is a test tube, and the rack 2 can be provided with a round hole matched with the test tube; for another example, the sample container is a rectangular parallelepiped container, and the rack 2 may be provided with a groove or the like that matches the rectangular parallelepiped container. According to some embodiments, the shelf 2 may contact the periphery of the inner wall of the case 1, or may have a certain gap with the inner wall, for example, may have a spacing of 5cm. According to some embodiments, the rack 2 may be made of a low-temperature resistant stainless steel material, so that heat can be conducted rapidly, and thus the rack 2 can be pre-cooled rapidly.

In the prior art, low-temperature consumables such as dry ice, ice blocks are placed at the bottom of the incubator, and samples are stored on the low-temperature consumables. However, this arrangement is disadvantageous in that the sample is smoothly placed, and the temperature distribution inside the case 1 is also severely uneven.

In this regard, according to some embodiments, the present application provides a partition plate 3 inside the case 1, as shown in fig. 5. The partition plate 3 may be of a perforated structure or a straight plate structure, etc. The division board 3 is located between the mount 16 in the box 1, and low temperature consumptive materials such as dry ice, ice-cube are located between box 1 inner wall and division board 3, and division board 3 separates low temperature consumptive material and supporter 2. In the case where the shelf 2 is stored in the case 1, the shelf 2 is located in the partition plate 3. The shelf 2 may contact the partition plate 3 or have a certain gap with the partition plate 3.

Through set up division board 3 in box 1 inside, need not to all arrange the low temperature consumptive material in box 1 bottom, can also place between box 1 inner wall and division board 3 for the temperature distribution of box 1 inner wall is more even.

According to the sample pre-cooling monitoring device provided by the application, on one hand, the current temperature inside the box body 1 can be monitored in real time through the temperature sensor and the temperature display 13, so that an operator can conveniently know whether the pre-cooling of the box body 1 reaches the preset condition or not and whether the sample is at a proper temperature or not in the process of operating the sample in the box, and the invisible sample is prevented from being damaged. On the other hand, the rack 2 is arranged in the box body 1, so that the samples can be conveniently transferred, stored and operated. In addition, the box body 1 adopts high-performance heat preservation materials such as high-density polyurethane materials or vacuum heat preservation materials, so that the internal and external temperatures of the box body 1 can be effectively isolated, and the loss of low-temperature consumables in the box body 1 is reduced.

The foregoing has outlined rather broadly the more detailed description of embodiments of the application in order that the detailed description of the principles and embodiments of the application may be implemented in conjunction with the detailed description of embodiments of the application that follows. Meanwhile, based on the idea of the present application, those skilled in the art can make changes or modifications on the specific embodiments and application scope of the present application, which belong to the protection scope of the present application. In view of the foregoing, this description should not be construed as limiting the application.

Claims

1. A pre-cooling monitoring device for a sample, comprising:

the box body is used for placing a sample;

The temperature display is positioned outside the box body and used for displaying the temperature measured by the temperature sensor;

2. The pre-cooling monitoring device of claim 1, wherein the temperature sensor is located at an opening of the tank.

3. The pre-cooling monitoring device of claim 1, wherein the temperature sensor comprises a first temperature sensor and a second temperature sensor, wherein the first temperature sensor is located at an opening of the tank and the second temperature sensor is located at an inner bottom of the tank.

4. The pre-cooling monitoring device of claim 3, further comprising one or more temperature sensors between the first temperature sensor and the second temperature sensor, the one or more temperature sensors configured to measure a temperature between an opening of the tank and an inside bottom of the tank.

5. The pre-cooling monitoring device of claim 1, further comprising:

6. The pre-cooling monitoring device of claim 1, wherein the temperature display is mounted around the exterior of the cabinet.

7. The pre-cooling monitoring device of claim 1, wherein the material of the tank is a high performance insulating material.

8. The pre-chill monitoring apparatus of claim 1, wherein the mount is configured to mate with a structure of the rack that mates with a structure of a sample container to be placed.

9. The pre-cooling monitoring device of claim 1, wherein a cover is provided at an opening of the tank.