CN220905787U - Specific T cell detection kit - Google Patents
Specific T cell detection kit Download PDFInfo
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- CN220905787U CN220905787U CN202322582700.3U CN202322582700U CN220905787U CN 220905787 U CN220905787 U CN 220905787U CN 202322582700 U CN202322582700 U CN 202322582700U CN 220905787 U CN220905787 U CN 220905787U
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- 210000001744 T-lymphocyte Anatomy 0.000 title claims abstract description 23
- 238000001514 detection method Methods 0.000 title claims abstract description 15
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 53
- 238000007789 sealing Methods 0.000 claims abstract 2
- 239000004065 semiconductor Substances 0.000 claims description 11
- 238000003149 assay kit Methods 0.000 claims description 7
- 238000000926 separation method Methods 0.000 claims description 7
- 210000004027 cell Anatomy 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 238000005057 refrigeration Methods 0.000 description 7
- 230000003044 adaptive effect Effects 0.000 description 2
- 238000013016 damping Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000012398 clinical drug development Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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Abstract
The utility model provides a specific T cell detection kit, which relates to the field of cell detection kits and comprises a kit body, wherein the kit body comprises a kit body and a box cover, the box cover is used for sealing the kit body, the kit body and the box cover are used for providing a storage space for a reagent tube, a placement component is arranged in an inner cavity of the kit body and used for supporting the reagent tube, a clamping component is arranged on the surface of the placement component, and the clamping component is used for clamping and fixing the reagent tube; according to the utility model, the effect of placing the reagent tube is achieved by arranging the reagent box body and the placing component, the box body and the box cover are matched to provide a storage space, the placing component can support the reagent tube, and the clamping component is arranged to achieve the effect of clamping and fixing the reagent tube, so that the reagent tube with different sizes can be used for storing specific T cells and reagents, and the use flexibility of the reagent box body is effectively improved.
Description
Technical Field
The utility model belongs to the field of cell detection kits, and particularly relates to a specific T cell detection kit.
Background
The cell detection kit is used for containing detection reagents and a box for detecting cells to be detected, is used for detecting and analyzing functions, states and biological characteristics of the cells, can be used for quantitatively or qualitatively detecting various parameters of the cells, is widely applied to the fields of immunological research, clinical diagnosis, drug development and the like, and is used for detecting the specific T cells, namely lymphocytes in an immune system, and has high specific antigen recognition and immune response capacity;
According to the Chinese patent application number: 201821367464.6 discloses a cell detection kit, which comprises a kit body, a box cover, a bottom plate, supporting feet, a buckle, a fixing strip, a small-size reagent bottle hole, a medium-size reagent bottle hole, a large-size reagent bottle hole, a first fixing ring, a second fixing ring, a third fixing ring and a damping structure, wherein the box cover is connected with the kit body, the bottom plate is fixed at the bottom end of the kit body, the supporting feet are fixed at the bottom end of the bottom plate, the buckle is fixed at the outer side of the kit body, the fixing strip is fixed at the inner side of the kit body, the small-size reagent bottle hole is positioned at the inner side of the kit body, the medium-size reagent bottle hole is positioned at the inner side of the kit body, the first fixing ring is fixed on the small-size reagent bottle hole, the second fixing ring is fixed on the medium-size reagent bottle hole, the third fixing ring is fixed on the large-size reagent bottle hole, and the damping structure is positioned on the kit body;
The effectual problem of damaging takes place for the reagent pipe in the kit of detection in-process of having solved of contrast case has the advantage that can fix the reagent pipe, but the fixed mode in this kind of kit is fixed the reagent pipe of equidimension not through setting up the reagent groove of multiunit equidimension, although can play fixed effect to the reagent pipe, but this kind of design is comparatively loaded down with trivial details for every reagent groove can only correspond the reagent pipe of equidimension, thereby leads to the use quantity of the reagent pipe of equidimension not to receive certain restriction, and then reduced the flexibility of using.
In summary, the present utility model provides a specific T cell assay kit to solve the above problems.
Disclosure of utility model
In order to solve the technical problems, the utility model provides the following technical scheme:
the utility model provides a specificity T cell detection kit, includes the kit body, the kit body includes box body and lid, the lid is used for closing cap to the box body, box body and lid are used for providing the parking space to the reagent pipe, the inner chamber of box body is provided with places the subassembly, place the subassembly and be used for supporting the reagent pipe, place the surface mounting of subassembly and have the clamping component, the clamping component is used for carrying out the centre gripping to the reagent pipe fixedly, refrigeration subassembly is installed to the inner chamber of box body, refrigeration subassembly is used for providing the air conditioning to the inner chamber of box body.
Further, in the utility model, the placement component comprises a fixing plate, a bracket and a slot, wherein the fixing plate is positioned in the inner cavity of the box body and is fixedly connected with the inner cavity of the box body, the bracket is positioned in the inner cavity of the fixing plate and is movably connected with the inner cavity of the fixing plate, and the slot is formed in the surface of the bracket.
Further, in the utility model, the placing component further comprises a baffle block and a fixed block, wherein the baffle block is fixed on two sides of the inner cavity of the fixed plate, the fixed block is fixed on two sides of the bracket, and the top of the baffle block is contacted with the bottom of the fixed block.
Further, in the utility model, the clamping assembly comprises a mounting box, a clamping plate, a connecting plate and a spring, wherein the mounting box is fixedly connected with the bracket, the clamping plate is positioned at the top of the fixing plate, the connecting plate is positioned in the inner cavity of the mounting box and is movably connected with the inner cavity of the mounting box, the top of the connecting plate penetrates through the outside of the mounting box and is fixedly connected with the clamping plate, and the spring is positioned in the inner cavity of the mounting box and is fixedly connected with the inner wall of the mounting box and the connecting plate respectively at two ends of the spring.
Further, in the utility model, the clamping assembly further comprises a limit groove and limit blocks, wherein the limit groove is formed in two sides of the inner cavity of the mounting box, the limit blocks are located in the inner cavity of the limit groove and are movably connected with the inner cavity of the limit groove, and one end, far away from the limit groove, of each limit block is movably connected with the connecting plate through a bearing.
Further, in the utility model, the refrigerating component comprises a PLC (programmable logic controller), a semiconductor refrigerator, a temperature sensor and a separation net, wherein the PLC is fixedly connected with the box body, and the semiconductor refrigerator, the temperature sensor and the separation net are fixedly connected with the inner wall of the box body.
Further, in the utility model, the output end of the temperature sensor is electrically connected with the input end of the PLC, and the output end of the PLC is electrically connected with the input end of the temperature sensor.
The utility model has the following beneficial effects:
According to the utility model, the effect of placing the reagent tube is achieved by arranging the reagent box body and the placing component, the box body and the box cover are matched to provide a storage space, the placing component can support the reagent tube, and the clamping component is arranged to achieve the effect of clamping and fixing the reagent tube, so that the reagent tube with different sizes can be used for storing cells and reagents, and the use flexibility of the reagent box body is effectively improved.
Drawings
FIG. 1 is a schematic diagram of the front view of the present utility model;
FIG. 2 is a schematic diagram of the front view of the placement module of the present utility model;
FIG. 3 is a schematic cross-sectional view of the cartridge of the present utility model;
FIG. 4 is a schematic view of the clamping assembly of the present utility model in a separated state;
fig. 5 is a schematic view of a partially enlarged structure at a in fig. 1 according to the present utility model.
In the figure:
1. A kit body; 11. a case body; 12. a box cover; 2. placing the assembly; 21. a fixing plate; 22. a bracket; 23. a slot; 24. a stop block; 25. a fixed block; 3. a clamping assembly; 301. a mounting box; 302. a clamping plate; 303. a connecting plate; 304. a spring; 305. a limit groove; 306. a limiting block; 4. a refrigeration assembly; 41. a PLC controller; 42. a semiconductor refrigerator; 43. a temperature sensor; 44. a separation net.
Detailed Description
For a better understanding of the technical content of the present utility model, specific examples are set forth below, along with the accompanying drawings. Aspects of the utility model are described in this disclosure with reference to the drawings, in which are shown a number of illustrative embodiments. The embodiments of the present disclosure need not be defined to include all aspects of the present utility model. It should be understood that the various concepts and embodiments described above, as well as those described in more detail below, may be implemented in any of a number of ways, as the disclosed concepts and embodiments are not limited to any implementation. Additionally, some aspects of the disclosure may be used alone or in any suitable combination with other aspects of the disclosure.
Example 1
As shown in fig. 1-5, a first embodiment of the present utility model provides a specific T cell detection kit, which includes a kit body 1, where the kit body 1 includes a box body 11 and a box cover 12, the box cover 12 is used to cover the box body 11, the box body 11 and the box cover 12 are used to provide a storage space for a reagent tube, an inner cavity of the box body 11 is provided with a placement component 2, the placement component 2 is used to support the reagent tube, a clamping component 3 is installed on a surface of the placement component 2, the clamping component 3 is used to clamp and fix the reagent tube, a refrigeration component 4 is installed in an inner cavity of the box body 11, and the refrigeration component 4 is used to provide cold air for an inner cavity of the box body 11.
As shown in fig. 1-5, the temperature of the inner cavity of the box body 11 is firstly adjusted through the refrigerating component 4 to reach the adaptive temperature of the specific T cells, the reagent tube containing the specific T cells and the reagent liquid is inserted into the inner cavity of the placing component 2, the clamping component 3 can clamp and fix the reagent tube, and then the box body 11 is covered by the box cover 12, so that the inner cavity of the box body 11 can be sealed.
Example 2
Referring to fig. 2, 4 and 5, for the second embodiment of the present utility model, this embodiment is based on the previous embodiment.
In this embodiment, the placement component 2 includes a fixing plate 21, a bracket 22 and a slot 23, the fixing plate 21 is located in the inner cavity of the box body 11 and is fixedly connected with the inner cavity of the box body 11, the bracket 22 is located in the inner cavity of the fixing plate 21 and is movably connected with the inner cavity of the fixing plate 21, and the slot 23 is formed on the surface of the bracket 22.
The placement component 2 further comprises a baffle 24 and a fixed block 25, wherein the baffle 24 is fixed on two sides of the inner cavity of the fixed plate 21, the fixed block 25 is fixed on two sides of the bracket 22, and the top of the baffle 24 is contacted with the bottom of the fixed block 25.
The clamping assembly 3 comprises a mounting box 301, a clamping plate 302, a connecting plate 303 and a spring 304, wherein the mounting box 301 is fixedly connected with the support 22, the clamping plate 302 is positioned at the top of the fixed plate 21, the connecting plate 303 is positioned in the inner cavity of the mounting box 301 and movably connected with the inner cavity of the mounting box 301, the top of the connecting plate 303 penetrates through the outer part of the mounting box 301 and is fixedly connected with the clamping plate 302, the spring 304 is positioned in the inner cavity of the mounting box 301, and two ends of the spring 304 are respectively fixedly connected with the inner wall of the mounting box 301 and the connecting plate 303.
The clamping assembly 3 further comprises a limiting groove 305 and limiting blocks 306, the limiting groove 305 is formed in two sides of the inner cavity of the mounting box 301, the limiting blocks 306 are located in the inner cavity of the limiting groove 305 and movably connected with the inner cavity of the limiting groove 305, and one end, away from the limiting groove 305, of each limiting block 306 is movably connected with the connecting plate 303 through a bearing.
As shown in fig. 2, 4 and 5, the bracket 22 is inserted into the inner cavity of the fixing plate 21, so that the stop block 24 is in contact with the fixing block 25, then the clamping plate 302 is pressed, the connecting plate 303 is driven to move downwards when the clamping plate 302 moves downwards, the limiting block 306 is driven to move downwards along the inner cavity of the limiting groove 305 when the connecting plate 303 moves downwards, the spring 304 is extruded while the connecting plate 303 moves downwards, so that the spring 304 is stressed to deform, then the reagent tube is inserted into the inner cavity of the slot 23, the reset elastic force of the spring 304 pushes the connecting plate 303 to move upwards, and the clamping plate 302 is pushed to clamp and fix the reagent tube when the connecting plate 303 moves upwards, and each two clamping plates 302 are in a group, so that the reagent tube can be fixed, and the reagent tube is used for containing detection reagent and specific T cells.
Example 3
Referring to fig. 1 and 3, a third embodiment of the present utility model is based on the first two embodiments.
In this embodiment, the refrigeration assembly 4 includes a PLC controller 41, a semiconductor refrigerator 42, a temperature sensor 43 and a separation net 44, where the PLC controller 41 is fixedly connected with the box 11, and the semiconductor refrigerator 42, the temperature sensor 43 and the separation net 44 are fixedly connected with the inner wall of the box 11.
An output end of the temperature sensor 43 is electrically connected to an input end of the PLC controller 41, and an output end of the PLC controller 41 is electrically connected to an input end of the temperature sensor 43.
As shown in fig. 1 and 3, the cold air emitted by the semiconductor refrigerator 42 can cool the inner cavity of the box body 11, so that specific T cells can be refrigerated, the temperature sensor 43 can detect the temperature of the inner cavity of the box body 11 and send the detection result to the PLC controller 41, the refrigeration temperature can be adjusted by the PLC controller 41, the temperature sensor 43 can be of HC-WSB208 type, and the semiconductor refrigerator 42 can be of TEC1-12706 type.
When the device is used, the temperature of the inner cavity of the box body 11 is set through the PLC 41, the PLC 41 controls the semiconductor refrigerator 42 to start, cold air generated by the semiconductor refrigerator 42 cools the inner cavity of the box body 11, so that the adaptive temperature of the specific T cells is achieved, then the support 22 is inserted into the inner cavity of the fixed plate 21, the baffle 24 is contacted with the fixed block 25, then the clamping plate 302 is pressed, the connecting plate 303 is driven to move downwards when the clamping plate 302 moves downwards, the limiting block 306 is driven to move downwards along the inner cavity of the limiting groove 305 when the connecting plate 303 moves downwards, the spring 304 is extruded while the connecting plate 303 moves downwards, the stress of the spring 304 is deformed, then a reagent tube for containing the specific T cells is inserted into the inner cavity of the slot 23, the reset elastic force of the spring 304 pushes the connecting plate 303 to move upwards, and the clamping plate 302 is pushed to clamp and fix the reagent tube for containing the specific T cells when the connecting plate 303 moves upwards.
Standard parts used in the file of the application can be purchased from market, and can be customized according to the description of the specification and the drawings, the specific connection modes of all parts adopt conventional means such as mature bolts, rivets, welding and the like in the prior art, the machinery, the parts and the equipment adopt conventional models in the prior art, the control mode is controlled automatically by a controller, a control circuit of the controller can be realized by simple programming of a person skilled in the art, the application belongs to common general knowledge in the art, and the application is mainly used for protecting mechanical devices, so the application does not explain the control mode and circuit connection in detail.
While the utility model has been described with reference to preferred embodiments, it is not intended to be limiting. Those skilled in the art will appreciate that various modifications and adaptations can be made without departing from the spirit and scope of the present utility model. Accordingly, the scope of the utility model is defined by the appended claims.
Claims (7)
1. The utility model provides a specificity T cell detection kit, includes kit body (1), its characterized in that: the kit body (1) comprises a box body (11) and a box cover (12), the box cover (12) is used for sealing the box body (11), the box body (11) and the box cover (12) are used for providing a storage space for the reagent tube, an inner cavity of the box body (11) is provided with a placement component (2), the placement component (2) is used for supporting the reagent tube, a clamping component (3) is arranged on the surface of the placement component (2), the clamping component (3) is used for clamping and fixing the reagent tube, a refrigerating component (4) is arranged in the inner cavity of the box body (11), and the refrigerating component (4) is used for providing cold air for the inner cavity of the box body (11).
2. The specific T cell assay kit of claim 1, wherein: the placement component (2) comprises a fixing plate (21), a support (22) and a slot (23), wherein the fixing plate (21) is located in the inner cavity of the box body (11) and is fixedly connected with the inner cavity of the box body (11), the support (22) is located in the inner cavity of the fixing plate (21) and is movably connected with the inner cavity of the fixing plate (21), and the slot (23) is formed in the surface of the support (22).
3. The specific T cell assay kit of claim 2, wherein: the placement assembly (2) further comprises a baffle block (24) and a fixing block (25), wherein the baffle block (24) is fixed on two sides of an inner cavity of the fixing plate (21), the fixing block (25) is fixed on two sides of the support (22), and the top of the baffle block (24) is in contact with the bottom of the fixing block (25).
4. The specific T cell assay kit of claim 1, wherein: clamping assembly (3) are including mounting box (301), grip block (302), connecting plate (303) and spring (304), mounting box (301) and support (22) fixed connection, grip block (302) are located the top of fixed plate (21), connecting plate (303) are located the inner chamber of mounting box (301) and with the inner chamber swing joint of mounting box (301), the top of connecting plate (303) runs through to the outside of mounting box (301) and with grip block (302) fixed connection, spring (304) are located the inner chamber of mounting box (301), and with the both ends of spring (304) respectively with the inner wall of mounting box (301) and connecting plate (303) fixed connection.
5. The specific T cell assay kit of claim 4, wherein: the clamping assembly (3) further comprises a limiting groove (305) and limiting blocks (306), the limiting groove (305) is formed in two sides of the inner cavity of the mounting box (301), the limiting blocks (306) are located in the inner cavity of the limiting groove (305) and are movably connected with the inner cavity of the limiting groove (305), and one end, far away from the limiting groove (305), of each limiting block (306) is movably connected with the connecting plate (303) through a bearing.
6. The specific T cell assay kit of claim 1, wherein: the refrigerating assembly (4) comprises a PLC (programmable logic controller) (41), a semiconductor refrigerator (42), a temperature sensor (43) and a separation net (44), wherein the PLC (41) is fixedly connected with the box body (11), and the semiconductor refrigerator (42), the temperature sensor (43) and the separation net (44) are fixedly connected with the inner wall of the box body (11).
7. The specific T cell assay kit of claim 6, wherein: the output end of the temperature sensor (43) is electrically connected with the input end of the PLC (41), and the output end of the PLC (41) is electrically connected with the input end of the temperature sensor (43).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322582700.3U CN220905787U (en) | 2023-09-22 | 2023-09-22 | Specific T cell detection kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322582700.3U CN220905787U (en) | 2023-09-22 | 2023-09-22 | Specific T cell detection kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220905787U true CN220905787U (en) | 2024-05-07 |
Family
ID=90906478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322582700.3U Active CN220905787U (en) | 2023-09-22 | 2023-09-22 | Specific T cell detection kit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220905787U (en) |
-
2023
- 2023-09-22 CN CN202322582700.3U patent/CN220905787U/en active Active
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