CN220899779U - Enzymolysis liquid filter tank is used in heparin sodium production - Google Patents
Enzymolysis liquid filter tank is used in heparin sodium production Download PDFInfo
- Publication number
- CN220899779U CN220899779U CN202322699007.4U CN202322699007U CN220899779U CN 220899779 U CN220899779 U CN 220899779U CN 202322699007 U CN202322699007 U CN 202322699007U CN 220899779 U CN220899779 U CN 220899779U
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- CN
- China
- Prior art keywords
- fixedly connected
- tank
- cooling
- cooling tank
- enzymolysis liquid
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- 239000007788 liquid Substances 0.000 title claims abstract description 60
- 229920000669 heparin Polymers 0.000 title claims abstract description 17
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 title claims abstract description 17
- 229960001008 heparin sodium Drugs 0.000 title claims abstract description 17
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 16
- 238000001816 cooling Methods 0.000 claims abstract description 73
- 238000010438 heat treatment Methods 0.000 claims abstract description 14
- 239000000463 material Substances 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 8
- 239000000956 alloy Substances 0.000 claims description 5
- 229910045601 alloy Inorganic materials 0.000 claims description 5
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 5
- 229910052782 aluminium Inorganic materials 0.000 claims description 5
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 230000002255 enzymatic effect Effects 0.000 claims 4
- 239000000413 hydrolysate Substances 0.000 claims 4
- 238000001914 filtration Methods 0.000 abstract description 14
- 239000012295 chemical reaction liquid Substances 0.000 abstract description 12
- 238000000034 method Methods 0.000 abstract description 6
- 238000003756 stirring Methods 0.000 abstract description 5
- 239000000376 reactant Substances 0.000 description 11
- 239000000110 cooling liquid Substances 0.000 description 10
- 239000002826 coolant Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 239000003124 biologic agent Substances 0.000 description 2
- 230000017525 heat dissipation Effects 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 239000004019 antithrombin Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The application relates to the field of enzymolysis liquid filtering equipment, and discloses an enzymolysis liquid filtering tank for heparin sodium production, which comprises a motor, a tank body and a cooling tank, wherein a stirring shaft is fixedly connected to the bottom of the motor in the tank body, a filter plate is movably arranged in the tank body at the bottom of the stirring shaft, a heating pipe is fixedly connected to the inner side wall of the tank body, the cooling tank is fixedly connected to the bottom of the tank body, a cooling pipe is fixedly connected to the inside of the cooling tank, a temperature detector is fixedly connected to the surface of the cooling tank at one side of a controller, and cooling plates are fixedly connected to the two ends of the cooling tank at the bottom of the temperature detector. According to the application, through the cooperation of the distance meter, the electric push rod, the supporting plate and the controller, the enzymolysis liquid and the reaction liquid thereof can be rapidly cooled after being filtered, and the enzymolysis liquid and the reaction liquid thereof are automatically discharged after being cooled, so that the enzymolysis liquid and the reaction liquid thereof can be directly preprocessed by workers in the next working procedure after being filtered, and the working efficiency is improved.
Description
Technical Field
The application relates to the technical field of enzymolysis liquid filtering equipment, in particular to an enzymolysis liquid filtering tank for heparin sodium production.
Background
Heparin sodium is an anticoagulant, can interfere many links of the coagulation process, has anticoagulation effect in vivo and in vitro, has a complex action mechanism, and mainly enhances the inhibition effect of the anticoagulant enzyme III on activated II, IX, X, XI and XII coagulation factors by combining with the antithrombin enzyme III, so that an enzymolysis liquid is required to be utilized when the heparin sodium is produced, and a filter tank is required to be utilized when the enzymolysis liquid is filtered.
At present, due to the lack of a structure capable of assisting cooling, after the enzymolysis liquid reacts and is filtered, cooling and discharging cannot be automatically performed, and the enzymolysis liquid cannot be directly discharged due to higher temperature of the enzymolysis liquid, so that the next production process cannot be performed.
Disclosure of utility model
In order to solve the problems in the background art, the application provides an enzymolysis liquid filtering tank for heparin sodium production.
The application provides an enzymolysis liquid filtering tank for heparin sodium production, which adopts the following technical scheme:
The utility model provides an enzymolysis liquid filter tank is used in heparin sodium production, includes motor, jar body and cooling tank, the top fixedly connected with motor of jar body, the inside motor bottom fixedly connected with (mixing) shaft of jar, the inside movable mounting of jar of (mixing) shaft bottom has the filter, fixedly connected with heating pipe on the inside wall of jar body, the bottom fixedly connected with cooling tank of jar body, fixedly connected with pipe between jar body and the cooling tank, the peripheral fixedly connected with metering valve of pipe, the inside fixedly connected with cooling tube of cooling tank, the bottom fixedly connected with bleeder valve of cooling tank, the surface fixedly connected with controller of cooling tank, cooling tank surface fixedly connected with temperature detector of controller one side, the cooling tank both ends of temperature detector bottom are all fixedly connected with heating panel.
Through the inside with the enzymolysis liquid and other reactant introduction jar body, the motor drives the (mixing) shaft and rotates, the heating pipe circular telegram back is simultaneously heated jar body and inside material thereof, rethread filter filters enzymolysis liquid and reaction liquid, the inside of leading-in cooler bin of liquid after the filtration passes through the pipe, heat quick absorption and transfer to the air around with enzymolysis liquid and its reaction liquid through the heating panel, also can be with outside water-cooling liquid introduction structure and cooling tube are connected and are imported the coolant liquid, make the coolant liquid circulate in the inside of cooling tube, make enzymolysis liquid and its reaction liquid accomplish quick cold and heat exchange with the coolant liquid, realize carrying out quick cooling to enzymolysis liquid and its reaction liquid.
Preferably, the top of the tank body at two sides of the motor is fixedly connected with a feeding pipe, and the top of the feeding pipe is movably provided with a sealing cover.
The feeding pipe is sealed through the sealing cover, and staff can guide other biological agents such as enzymolysis liquid into the tank body through the feeding pipe by pulling the sealing cover down.
Preferably, the surface of cooling tank both sides all fixedly connected with bracing piece, and the bottom fixedly connected with antiskid ribbed tile of bracing piece.
The support is formed by the support rod and the ground, and the friction force between the support rod and the ground is increased by the anti-skid block, so that the stability effect of the device is improved.
Preferably, a positioning piece is fixedly connected between the controller and the cooling box, and a bolt is movably arranged between the positioning piece and the cooling box.
The contact area between the controller and the cooling box is increased through the locating piece, and the locating piece and the cooling box are fixed through the bolt, so that the stabilizing effect of the installation of the controller is improved.
Preferably, a supporting block is fixedly connected in the tank body at the bottom of the filter plate, and the supporting block is made of an alloy aluminum material.
Can support the filter through the supporting shoe, adopt alloy aluminium material to make the supporting shoe have higher intensity, reduced the possibility that the supporting shoe damaged.
In summary, the application has the following beneficial technical effects:
Through the inside with its leading-in cooler bin after enzymolysis liquid and its reaction liquid filtration are accomplished, absorb the heat of enzymolysis liquid and its reaction liquid fast and transmit the air around through the heating panel, also can be with outside water-cooling liquid leading-in structure and cooling tube are connected, the inside with the cooling liquid leading-in cooling tube, make the cooling liquid circulate in the inside of cooling tube, make enzymolysis liquid and its reaction liquid accomplish quick cold and heat exchange with the cooling liquid, realize carrying out quick cooling to enzymolysis liquid and its reaction liquid, when temperature detector detects the temperature and can carry out next process, open through controller automatic control bleeder valve, realize automatic row material, thereby the staff of being convenient for directly carries out the preliminary treatment of next process to it after enzymolysis liquid and its reaction liquid filtration.
Drawings
FIG. 1 is an overall perspective view of an embodiment of the application;
FIG. 2 is a front view of an embodiment of the application;
FIG. 3 is a schematic diagram of the internal structure of an embodiment of the application;
fig. 4 is a control flow chart of the application embodiment.
Reference numerals illustrate: 1. a motor; 2. a feed pipe; 201. sealing cover; 3. a tank body; 4. a cooling box; 5. a temperature detector; 6. a heat dissipation plate; 7. a controller; 701. a positioning piece; 8. a support rod; 801. an anti-skid block; 9. a discharge valve; 10. heating pipes; 11. a filter plate; 12. a metering valve; 13. a cooling tube; 14. a conduit; 15. a stirring shaft; 16. and a supporting block.
Detailed Description
The application is described in further detail below with reference to fig. 1-4.
The embodiment of the application discloses an enzymolysis liquid filtering tank for heparin sodium production. Referring to fig. 1-4, an enzymolysis liquid filtering tank for heparin sodium production comprises a motor 1, a tank body 3 and a cooling tank 4, wherein the top of the tank body 3 is fixedly connected with the motor 1, the bottom of the motor 1 inside the tank body 3 is fixedly connected with a stirring shaft 15, a filter plate 11 is movably installed inside the tank body 3 at the bottom of the stirring shaft 15, a heating pipe 10 is fixedly connected to the inner side wall of the tank body 3, the cooling tank 4 is fixedly connected to the bottom of the tank body 3, a guide pipe 14 is fixedly connected between the tank body 3 and the cooling tank 4, a metering valve 12 is fixedly connected to the periphery of the guide pipe 14, a cooling pipe 13 is fixedly connected to the inside of the cooling tank 4, a discharge valve 9 is fixedly connected to the bottom of the cooling tank 4, a controller 7 is fixedly connected to the surface of the cooling tank 4 at one side of the controller 7, a temperature detector 5 is fixedly connected to both ends of the cooling tank 4 at the bottom of the temperature detector 5, and a heat dissipation plate 6 is fixedly connected to both ends of the cooling tank 4 at the bottom of the temperature detector 5.
Staff is through leading into the inside of jar body 3 with enzymolysis liquid and other reactant, drive (mixing) shaft 15 through control motor 1 and rotate, simultaneously after heating pipe 10 circular telegram carries out the heating to jar body 3 and its inside material, rethread filter 11 filters enzymolysis liquid and reactant liquid, the inside of cooling tank 4 is led into to the liquid after the filtration through pipe 14, can detect the liquid volume of leading into cooling tank 4 inside through metering valve 12, when reaching the biggest volume of cooling tank 4, through controller 7 automatic control metering valve 12 closing, can absorb enzymolysis liquid and reactant liquid's heat fast and transmit the air around for, realize carrying out quick cooling to enzymolysis liquid and reactant liquid, also can be connected outside water-cooling liquid introduction structure and cooling tube 13, lead into the inside of cooling tube 13, make the inside circulation flow of cooling tube 13, cooling tube 13 is the copper material of leading temperature, can make enzymolysis liquid and reactant liquid accomplish quick exchange with the cooling liquid, realize carrying out the quick cooling liquid and detect the temperature detector through temperature detector 5, can realize the automatic control process when the temperature controller is opened to the cooling tank 9, can realize the automatic control process when the temperature detector is carried out to the temperature detector is cooled down to the temperature controller 7.
Referring to fig. 1, a feed pipe 2 is fixedly connected to the top of a tank body 3 at two sides of a motor 1, a sealing cover 201 is movably mounted at the top of the feed pipe 2, the feed pipe 2 is sealed through the sealing cover 201, and a worker can introduce enzymolysis liquid and other biological agents into the tank body 3 through the feed pipe 2 by pulling down the sealing cover 201.
Referring to fig. 1, the surfaces of both sides of the cooling box 4 are fixedly connected with support rods 8, and the bottoms of the support rods 8 are fixedly connected with anti-slip blocks 801, so that a support is formed by the support rods 8 and the ground, friction force between the support rods 8 and the ground is increased by the anti-slip blocks 801, and the stability effect of device placement is improved.
Referring to fig. 2, a positioning member 701 is fixedly connected between the controller 7 and the cooling tank 4, and a bolt is movably installed between the positioning member 701 and the cooling tank 4, so that the contact area between the controller 7 and the cooling tank 4 is increased through the positioning member 701, and the positioning member 701 and the cooling tank 4 are fixed through the bolt, thereby increasing the stabilizing effect of the installation of the controller 7.
Referring to fig. 3, the support block 16 is fixedly connected to the inside of the tank body 3 at the bottom of the filter plate 11, and the support block 16 is made of an alloy aluminum material, so that the filter plate 11 can be supported by the support block 16, and the support block 16 has higher strength due to the alloy aluminum material, so that the possibility of damage of the support block 16 is reduced.
The implementation principle of the enzymolysis liquid filtering tank for heparin sodium production provided by the embodiment of the application is as follows: through leading into the inside of jar body 3 with enzymolysis liquid and other reactant, motor 1 drives (mixing) shaft 15 and rotates, heating pipe 10 circular telegram back is simultaneously heated jar body 3 and its inside material, rethread filter 11 filters enzymolysis liquid and reactant liquid, the inside of cooling tank 4 is led into to the liquid after the filtration through pipe 14, heat quick absorption and the transmission of enzymolysis liquid and its reactant liquid give the surrounding air through heating panel 6, also can be with outside water-cooling liquid leading-in structure and be connected with cooling tube 13, with the inside of cooling liquid leading-in cooling tube 13, make the coolant liquid circulate in the inside of cooling tube 13, make enzymolysis liquid and its reactant liquid accomplish quick cold and hot exchange with the coolant liquid, realize carrying out quick cooling to enzymolysis liquid and reactant liquid.
The last points to be described are: first, in the description of the present application, it should be noted that, unless otherwise specified and defined, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be mechanical or electrical, or may be a direct connection between two elements, and "upper," "lower," "left," "right," etc. are merely used to indicate relative positional relationships, which may be changed when the absolute position of the object being described is changed;
secondly: in the drawings of the disclosed embodiments, only the structures related to the embodiments of the present disclosure are referred to, and other structures can refer to the common design, so that the same embodiment and different embodiments of the present disclosure can be combined with each other under the condition of no conflict;
Finally: the foregoing description of the preferred embodiments of the utility model is not intended to limit the utility model to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and principles of the utility model are intended to be included within the scope of the utility model.
The above embodiments are not intended to limit the scope of the present application, so: all equivalent changes in structure, shape and principle of the application should be covered in the scope of protection of the application.
Claims (5)
1. The utility model provides a heparin sodium production is with enzymolysis liquid filter tank, includes motor (1), jar body (3) and cooling box (4), its characterized in that: the utility model discloses a cooling tank for a solar heat collector, including jar body (3), motor (1) of top fixedly connected with of jar body (3), motor (1) bottom fixedly connected with (15) of jar body (3) inside, jar body (3) inside movable mounting of (15) bottom has filter (11), fixedly connected with heating pipe (10) on the inside wall of jar body (3), the bottom fixedly connected with cooling tank (4) of jar body (3), fixedly connected with pipe (14) between jar body (3) and cooling tank (4), the peripheral fixedly connected with metering valve (12) of pipe (14), the inside fixedly connected with cooling tube (13) of cooling tank (4), the bottom fixedly connected with bleeder valve (9) of cooling tank (4), the fixed surface of cooling tank (4) is connected with controller (7), cooling tank (4) fixedly connected with temperature detector (5) on one side of controller (7), equal fixedly connected with heating panel (6) in cooling tank (4) both ends of temperature detector (5) bottom.
2. The enzymatic hydrolysate filter tank for heparin sodium production of claim 1, wherein: the top of the tank body (3) at two sides of the motor (1) is fixedly connected with a feeding pipe (2), and the top of the feeding pipe (2) is movably provided with a sealing cover (201).
3. The enzymatic hydrolysate filter tank for heparin sodium production of claim 1, wherein: the surface of cooling tank (4) both sides is all fixedly connected with bracing piece (8), and the bottom fixedly connected with antiskid piece (801) of bracing piece (8).
4. The enzymatic hydrolysate filter tank for heparin sodium production of claim 1, wherein: a positioning piece (701) is fixedly connected between the controller (7) and the cooling box (4), and a bolt is movably arranged between the positioning piece (701) and the cooling box (4).
5. The enzymatic hydrolysate filter tank for heparin sodium production of claim 1, wherein: the tank body (3) at the bottom of the filter plate (11) is internally fixedly connected with a supporting block (16), and the supporting block (16) is made of an alloy aluminum material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322699007.4U CN220899779U (en) | 2023-10-09 | 2023-10-09 | Enzymolysis liquid filter tank is used in heparin sodium production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322699007.4U CN220899779U (en) | 2023-10-09 | 2023-10-09 | Enzymolysis liquid filter tank is used in heparin sodium production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220899779U true CN220899779U (en) | 2024-05-07 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322699007.4U Active CN220899779U (en) | 2023-10-09 | 2023-10-09 | Enzymolysis liquid filter tank is used in heparin sodium production |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220899779U (en) |
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2023
- 2023-10-09 CN CN202322699007.4U patent/CN220899779U/en active Active
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