CN220788550U

CN220788550U - Improved PCR (polymerase chain reaction) amplification instrument

Info

Publication number: CN220788550U
Application number: CN202322477204.1U
Authority: CN
Inventors: 郝玮; 李小青
Original assignee: Wuhan Haixi Biotechnology Co ltd
Current assignee: Wuhan Haixi Biotechnology Co ltd
Priority date: 2023-09-11
Filing date: 2023-09-11
Publication date: 2024-04-16
Anticipated expiration: 2033-09-11

Abstract

The utility model discloses an improved PCR amplification instrument, which relates to the technical field of PCR amplification instruments and comprises a PCR amplification instrument body, wherein a locking mechanism comprises a first clamping groove formed in the front end of a cover plate, a sliding groove is formed in the front side of a groove, an electromagnet is fixedly connected to the front side of the sliding groove, a locking plate is connected in a sliding manner in the sliding groove, a magnet is fixedly connected to the front side of the locking plate, a group of first springs are fixedly connected to the rear side of the first clamping groove.

Description

Improved PCR (polymerase chain reaction) amplification instrument

Technical Field

The utility model relates to the technical field of PCR amplification instruments, in particular to an improved PCR amplification instrument.

Background

The PCR amplification instrument is also called a PCR gene amplification instrument, a PCR nucleic acid amplification instrument and a polymerase chain reaction nucleic acid amplification instrument, is an instrument device for amplifying specific DNA by utilizing a PCR technology, and is widely applied to medical and biological laboratories.

At present, a PCR amplification instrument is commonly used in a medical laboratory, and a cover of the existing PCR amplification instrument does not have an automatic locking function, so that an operator can inadvertently uncover the cover of the amplification instrument in operation, an amplification experiment cannot be smoothly performed, and meanwhile, potential safety hazards possibly exist. For this reason, an improved PCR amplification unit is needed to solve the above-mentioned technical problems.

Disclosure of Invention

The utility model aims to overcome the defects of the prior art and provides an improved PCR amplification instrument.

In order to achieve the above purpose, the present utility model provides the following technical solutions: an improved PCR amplification instrument comprises a PCR amplification instrument body, wherein the top end of the PCR amplification instrument body is provided with a groove, the bottom end of the groove is provided with a bottom groove, a cover plate is hinged in the groove, a fixed plate is fixedly connected in the bottom groove, the top end of the fixed plate is provided with a plurality of groups of slots, and the top of the PCR amplification instrument body is provided with a locking mechanism;

the locking mechanism comprises a first clamping groove formed in the front end of the cover plate, a sliding groove is formed in the front side of the groove, an electromagnet is fixedly connected to the front side of the sliding groove, a lock plate is connected in the sliding groove in a sliding mode, a magnet is fixedly connected to the front side of the lock plate, a first limiting groove is formed in the top end and the bottom end of the sliding groove, a first limiting block is fixedly connected to the front side of the top end and the bottom end of the lock plate, the first limiting block is located in the first limiting groove, a group of first springs are fixedly connected to the rear side of the first clamping groove, and connecting blocks are fixedly connected to the front ends of the first springs.

Preferably, the inside of PCR amplification appearance body is equipped with jack-up mechanism, the inner chamber has been seted up to the inside of jack-up mechanism, the L shape hole has all been seted up to the both sides on PCR amplification appearance body top, and the L shape hole all is linked together with the inner chamber, the equal sliding connection in one side that the fixed plate was kept away from in L shape hole has the slide, and the top of slide all extends to the top of PCR amplification appearance body, the bottom of slide all rigid coupling has a rack, the bottom of rack all rigid coupling has No. two springs, and the bottom of No. two springs all with the bottom rigid coupling of inner chamber, the downthehole all rotation of L shape is connected with the gear, and the gear all meshes with rack No. one, one side that the gear kept away from rack No. two is all meshed and is connected with rack No. two, and the lateral wall of rack No. two the bottom of rack all is rigid coupling has the connecting plate, the top rigid coupling of connecting plate has the movable rod, and the top of movable rod extends to the top of fixed plate, the top rigid coupling of movable rod has place the board, place the board top has the top of placing plate, the top of placing plate is equipped with the placing plate and places the test tube and has all offered a plurality of jacks.

Preferably, the bottom of connecting plate and two No. two racks all rigid couplings have a blotter, and the bottom of a blotter contacts with the bottom of inner chamber.

Preferably, the front sides of the first limiting grooves are fixedly connected with second buffering cushions, and the side surfaces of the second buffering cushions are contacted with the first limiting blocks.

Preferably, two clamping grooves are formed in the front sides of the sliding plates, and rotating plates are formed in the two sides of the top end of the PCR amplification instrument body.

Preferably, the top ends of the front sides of the two sliding plates are provided with the third clamping groove, and the thickness of the third clamping groove is the same as that of the rotating plate.

Preferably, no. two spacing grooves have all been seted up to the top and the bottom of draw-in groove, the top and the bottom of connecting block all rigid coupling have No. two stoppers, and No. two stoppers all are located No. two spacing grooves.

The beneficial effects are that:

compared with the prior art, the improved PCR amplification instrument has the following beneficial effects:

1. according to the utility model, the electromagnet is electrified, the electromagnet and the magnet repel each other, the locking plate slides in the chute to one side close to the first clamping groove, the elastic force of the first spring is overcome, the locking plate extrudes the connecting block, one end of the locking plate slides into the first clamping groove, at the moment, the locking of the cover plate is realized by the locking plate, after the power of the PCR amplification instrument body is cut off, the electromagnet is cut off, the repulsive force between the electromagnet and the magnet disappears, the connecting block ejects the locking plate into the chute again under the action of the first spring, so that unlocking is realized, and further, after the PCR amplification instrument body is started, the cover plate is automatically locked, the cover plate is prevented from being opened carelessly, the experiment is ensured to be carried out smoothly, and the potential safety hazard is eliminated.

2. According to the test tube detection device, the sliding plate is pressed downwards, the sliding plate drives the first rack to move downwards, the first rack drives the gear to rotate, the gear drives the second rack to move upwards, the second rack drives the connecting plate to move upwards, the connecting plate drives the movable rod to move upwards, the movable rod drives the placing plate to move upwards, the placing plate drives the test tube placing plate to move upwards, all test tubes are moved upwards by the test tube placing plate, at the moment, the whole of the processed test tubes can be conveniently taken out by a worker, and the efficiency of the worker in processing detection liquid in the test tubes is improved.

Drawings

FIG. 1 is a schematic perspective view of the present utility model;

FIG. 2 is a schematic cross-sectional view of the present utility model;

FIG. 3 is an enlarged schematic view of a portion of the utility model at A in FIG. 2;

FIG. 4 is a schematic view of another view angle structure of the present utility model;

fig. 5 is a schematic structural view of a jack-up mechanism in the present utility model.

In the figure: 1. a PCR amplification instrument body; 2. a groove; 3. a bottom groove; 4. a cover plate; 5. a fixing plate; 6. a slot; 7. a locking mechanism; 71. a first clamping groove; 72. an electromagnet; 73. a lock plate; 74. a magnet; 75. a first limit groove; 76. a first limiting block; 77. a chute; 78. a first spring; 79. a connecting block; 8. a jack-up mechanism; 80. an inner cavity; 81. an L-shaped aperture; 82. a slide plate; 83. a first rack; 84. a second spring; 85. a gear; 86. a second rack; 87. a connecting plate; 88. a movable rod; 89. placing a plate; 890. a test tube placing plate; 891. a jack; 9. a first cushion pad; 10. a second cushion pad; 11. a second clamping groove; 12. a rotating plate; 13. a third clamping groove; 14. a second limit groove; 15. and a second limiting block.

Detailed Description

The principles and features of the present utility model are described below with reference to the drawings, the examples are illustrated for the purpose of illustrating the utility model and are not to be construed as limiting the scope of the utility model.

As shown in fig. 1 to 5, an improved PCR amplification apparatus comprises a PCR amplification apparatus body 1, a groove 2 is provided at the top end of the PCR amplification apparatus body 1, a bottom groove 3 is provided at the bottom end of the groove 2, a cover plate 4 is hinged in the groove 2, a fixing plate 5 is fixedly connected in the bottom groove 3, a plurality of groups of slots 6 are provided at the top end of the fixing plate 5, the slots 6 can support and fix the test tube, and a locking mechanism 7 is provided at the top of the PCR amplification apparatus body 1.

The locking mechanism 7 comprises a first clamping groove 71 formed in the front end of the cover plate 4, a sliding groove 77 is formed in the front side of the groove 2, an electromagnet 72 is fixedly connected to the front side of the sliding groove 77, a locking plate 73 is connected in a sliding manner in the sliding groove 77, a magnet 74 is fixedly connected to the front side of the locking plate 73, a first limiting groove 75 is formed in the top end and the bottom end of the sliding groove 77, a first limiting block 76 is fixedly connected to the front sides of the top end and the bottom end of the locking plate 73, and the first limiting blocks 76 are located in the first limiting groove 75. The front side of the first limiting groove 75 is fixedly connected with the second buffering cushion 10, the side face of the second buffering cushion 10 is contacted with the first limiting block 76, and the design of the second buffering cushion 10 can buffer the locking plate 73 entering the sliding groove 77 after unlocking, so that the electromagnet 72 and the locking plate 73 are prevented from being impacted, and the electromagnet 72 and the locking plate 73 are prevented from being damaged. A group of first springs 78 are fixedly connected to the rear side of the first clamping groove 71, and a connecting block 79 is fixedly connected to the front end of each group of first springs 78. The second spacing groove 14 has all been seted up to the top and the bottom of draw-in groove 71, the top and the bottom of connecting block 79 have all been fixedly connected with No. two stopper 15, and No. two stopper 15 all are located No. two spacing groove 14, no. two spacing groove 14 and No. two stopper 15's design avoids under No. two spring 84 restoring force's effect, pops out draw-in groove 71 with connecting block 79 No. one, leads to No. one draw-in groove 71 can not recover, thereby realized spacing effect, make connecting block 79 can not be popped out in the draw-in groove 71 No. one.

When the PCR amplification instrument body 1 is powered on, the electromagnet 72 is electrified, the electromagnet 72 and the magnet 74 repel each other, the lock plate 73 slides in the chute 77 towards one side close to the first clamping groove 71 under the action of repulsive force, one end of the lock plate 73 slides out of the chute 77 and overcomes the elastic force of the first spring 78, the lock plate 73 extrudes the connecting block 79, the first spring 78 is compressed, one end of the lock plate 73 slides into the first clamping groove 71, at the moment, the lock plate 73 is utilized to lock the cover plate 4, after the PCR amplification instrument body 1 is powered off, the electromagnet 72 is powered off, the repulsive force between the electromagnet 72 and the magnet 74 disappears, the connecting block 79 springs the lock plate 73 into the chute 77 again under the action of the first spring 78 to realize unlocking, and then the cover plate 4 is automatically locked after the PCR amplification instrument body 1 is started, the cover plate 4 is prevented from being opened carelessly, the experiment is ensured to be carried out smoothly, and potential safety hazards are eliminated.

The inside of PCR amplification instrument body 1 is equipped with jack-up mechanism 8, and inner chamber 80 has been seted up to jack-up mechanism 8's inside, and L shape hole 81 has all been seted up to the both sides on PCR amplification instrument body 1 top, and L shape hole 81 all is linked together with inner chamber 80, and one side that L shape hole 81 kept away from fixed plate 5 all sliding connection has slide 82, and the top of slide 82 all extends to the top of PCR amplification instrument body 1. Two draw-in grooves 11 have all been seted up to the front side of two slide 82, and the rotatory board 12 has all been seted up to the both sides on PCR amplification instrument body 1 top, rotates rotatory board 12 to in No. two draw-in grooves 11, can avoid the staff carelessly to press slide 82, appear the test tube to shift up and bump with between the apron 4. The third clamping groove 13 is formed in the top ends of the front sides of the two sliding plates 82, the thickness of the third clamping groove 13 is the same as that of the rotating plate 12, after the sliding plates 82 are pressed, the rotating plate 12 is rotated into the third clamping groove 13, the state of the test tube placing plate 890 after upward moving is kept, and Fang Bai neon staff takes away the test tube. The bottom of slide 82 all rigid coupling has a rack 83, and the bottom of a rack 83 all rigid coupling has No. two springs 84, and the bottom of No. two springs 84 all with the bottom rigid coupling of inner chamber 80, all rotate in the L shape hole 81 and be connected with gear 85, and gear 85 all meshes with a rack 83 mutually, and one side that gear 85 kept away from a rack 83 all meshes and is connected with No. two racks 86, and the lateral wall of No. two racks 86 all laminates with the lateral wall of L shape hole 81 mutually, and the bottom of two racks 86 all rigid couplings has connecting plate 87. The bottom of connecting plate 87 and two No. two racks 86 all rigid couplings have a blotter 9, and the bottom of a blotter 9 contacts with the bottom of inner chamber 80, and the design of a blotter 9, after loosening slide 82, no. two springs 84 resume, and connecting plate 87 moves down, and a blotter 9 can cushion the impact that connecting plate 87 moves down and produces. The top rigid coupling of connecting plate 87 has movable rod 88, and the top of movable rod 88 extends to the top of fixed plate 5, and the top rigid coupling of movable rod 88 has places board 89, and the top of placing board 89 is equipped with test tube and places board 890, and a plurality of groups of jacks 891 have all been seted up on the top of placing board 89 and test tube and placing board 890.

After the test tube is inserted into the test tube placing plate 890, the test tube placing plate 890 is placed on the placing plate 89, the bottom end of the test tube enters the slot 6, when the test tube needs to be taken out, the sliding plate 82 is pressed downwards, the sliding plate 82 drives the first rack 83 to move downwards, the first rack 83 drives the gear 85 to rotate, the gear 85 drives the second rack 86 to move upwards, the second rack 86 drives the connecting plate 87 to move upwards, the connecting plate 87 drives the movable rod 88 to move upwards, the movable rod 88 drives the placing plate 89 to move upwards, the placing plate 89 drives the test tube placing plate 890 to move upwards, the test tube placing plate 890 moves all the test tubes upwards together, and at the moment, workers can take out the processed test tubes integrally, and the detection efficiency of the workers for processing test tube internal detection liquid is improved.

Working principle: when the PCR amplification instrument body 1 is powered on, the electromagnet 72 is electrified, the electromagnet 72 and the magnet 74 repel each other, the lock plate 73 slides in the chute 77 towards one side close to the first clamping groove 71 under the action of repulsive force, one end of the lock plate 73 slides out of the chute 77 and overcomes the elastic force of the first spring 78, the lock plate 73 extrudes the connecting block 79, the first spring 78 is compressed, one end of the lock plate 73 slides into the first clamping groove 71, at the moment, the lock plate 73 is utilized to lock the cover plate 4, after the PCR amplification instrument body 1 is powered off, the electromagnet 72 is powered off, the repulsive force between the electromagnet 72 and the magnet 74 disappears, the connecting block 79 springs the lock plate 73 into the chute 77 again under the action of the first spring 78 to realize unlocking, and then the cover plate 4 is automatically locked after the PCR amplification instrument body 1 is started, the cover plate 4 is prevented from being opened carelessly, the experiment is ensured to be carried out smoothly, and potential safety hazards are eliminated.

After the test tube is inserted into the test tube placing plate 890, then the test tube placing plate 890 is placed on the placing plate 89, the bottom end of the test tube enters the slot 6, when the test tube needs to be taken out, the sliding plate 82 is pressed downwards, the sliding plate 82 drives the first rack 83 to move downwards, the first rack 83 drives the gear 85 to rotate, the gear 85 drives the second rack 86 to move upwards, the second rack 86 drives the connecting plate 87 to move upwards, the connecting plate 87 drives the movable rod 88 to move upwards, the movable rod 88 drives the placing plate 89 to move upwards, the placing plate 89 drives the test tube placing plate 890 to move upwards, the test tube placing plate 890 moves all test tubes upwards together, and at the moment, workers can take out the processed test tubes integrally, and the detection efficiency of the workers for processing test tube internal detection liquid is improved.

The foregoing description of the preferred embodiments of the utility model is not intended to limit the utility model to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and scope of the utility model are intended to be included within the scope of the utility model.

Claims

1. An improved PCR amplification apparatus, comprising a PCR amplification apparatus body (1), characterized in that: the PCR amplification instrument comprises a PCR amplification instrument body (1), wherein a groove (2) is formed in the top end of the PCR amplification instrument body (1), a bottom groove (3) is formed in the bottom end of the groove (2), a cover plate (4) is hinged in the groove (2), a fixed plate (5) is fixedly connected in the bottom groove (3), a plurality of groups of slots (6) are formed in the top end of the fixed plate (5), and a locking mechanism (7) is arranged at the top of the PCR amplification instrument body (1);

the locking mechanism (7) comprises a first clamping groove (71) formed in the front end of the cover plate (4), a sliding groove (77) is formed in the front side of the groove (2), an electromagnet (72) is fixedly connected to the front side of the sliding groove (77), a lock plate (73) is connected to the sliding groove (77) in a sliding mode, a magnet (74) is fixedly connected to the front side of the lock plate (73), a first limiting groove (75) is formed in the top end and the bottom end of the sliding groove (77), a first limiting block (76) is fixedly connected to the front side of the top end and the bottom end of the lock plate (73), the first limiting block (76) is located in the first limiting groove (75), a group of first springs (78) are fixedly connected to the rear side of the first clamping groove (71), and connecting blocks (79) are fixedly connected to the front ends of the first springs (78).

2. An improved PCR amplification instrument according to claim 1, wherein: the inside of PCR amplification appearance body (1) is equipped with jack-up mechanism (8), inner chamber (80) have been seted up to the inside of jack-up mechanism (8), L shape hole (81) have all been seted up on the both sides on PCR amplification appearance body (1) top, and L shape hole (81) all are linked together with inner chamber (80), one side that fixed plate (5) was kept away from to L shape hole (81) all sliding connection has slide (82), and the top of slide (82) all extends to the top of PCR amplification appearance body (1), the bottom of slide (82) all rigid coupling has rack (83), the bottom of rack (83) all rigid coupling has spring (84) No. two, and the bottom rigid coupling of spring (84) No. two and inner chamber (80).

3. An improved PCR amplification instrument according to claim 2, characterized in that: all rotate in L shape hole (81) and be connected with gear (85), and gear (85) all meshes with rack (83) mutually, one side that rack (83) was kept away from to gear (85) all meshes to be connected with rack (86) No. two, and the lateral wall of rack (86) No. two all laminates with the lateral wall of L shape hole (81) mutually, two the bottom of rack (86) No. two all rigid couplings have connecting plate (87), the top rigid coupling of connecting plate (87) has movable rod (88), and the top of movable rod (88) extends to the top of fixed plate (5), the top rigid coupling of movable rod (88) has place board (89), the top of placing board (89) is equipped with test tube and places board (890), place board (89) and test tube and place the top of board (890) and all offered a plurality of jack (891) of groups.

4. An improved PCR amplification instrument according to claim 3, characterized in that: the bottom ends of the connecting plate (87) and the two second racks (86) are fixedly connected with a first buffer pad (9), and the bottom end of the first buffer pad (9) is contacted with the bottom end of the inner cavity (80).

5. An improved PCR amplification instrument according to claim 1, wherein: the front sides of the first limiting grooves (75) are fixedly connected with second buffering cushions (10), and the side surfaces of the second buffering cushions (10) are in contact with the first limiting blocks (76).

6. An improved PCR amplification instrument according to claim 3, characterized in that: two the draw-in grooves (11) are all offered to the front side of slide (82), rotating plate (12) have all been offered to both sides on PCR amplification instrument body (1) top.

7. The improved PCR amplification instrument as set forth in claim 6, wherein: and the top ends of the front sides of the two sliding plates (82) are respectively provided with a third clamping groove (13), and the thickness of the third clamping groove (13) is the same as that of the rotating plate (12).

8. An improved PCR amplification instrument according to claim 1, wherein: the top and the bottom of draw-in groove (71) all have seted up No. two spacing groove (14), the top and the bottom of connecting block (79) all have fixedly connected with No. two stopper (15), and No. two stopper (15) all are located No. two spacing groove (14).