CN220690354U

CN220690354U - Pipetting suction head tightness detection jig

Info

Publication number: CN220690354U
Application number: CN202322218725.5U
Authority: CN
Inventors: 陈芝娟; 张婷婷; 顾柳峰; 孔世龙; 贺贤汉
Original assignee: Anhui Bori Biotechnology Co ltd
Current assignee: Anhui Bori Biotechnology Co ltd
Priority date: 2023-08-17
Filing date: 2023-08-17
Publication date: 2024-03-29
Anticipated expiration: 2033-08-17

Abstract

The utility model discloses a pipetting head tightness detection jig which comprises a rack, a limiting plate and one or more detection modules, wherein the rack is provided with a plurality of detection modules; the rack is provided with detection positions corresponding to the number of the detection modules; the detection module comprises a support plate, a pipette tip, a piston cylinder and a driving handle; the supporting plate is fixed on the frame; the pipette gun head and the piston cylinder which are communicated with the inner cavity are fixed with the supporting plate; the suction head mounting port of the pipette gun head faces to the right lower part; the limiting plate is fixed on the frame; the driving handle is positioned between the limiting plate and the supporting plate; the limiting plate and the supporting plate respectively limit two limit positions of the driving handle. According to the utility model, the measured liquid-transfering suction head is arranged on the liquid-transfering device gun head corresponding to the specification detection position, and the dripping condition of the measured liquid-transfering suction head at the suction port of the liquid-transfering suction head when the liquid with different capacities is sucked is observed; the staff can intuitively detect the sealing condition when the liquid is sucked when the detected liquid-transfering sucker works.

Description

Pipetting suction head tightness detection jig

Technical Field

The utility model belongs to the technical field of suction head tightness detection for automatic pipetting equipment, and particularly relates to a pipetting suction head tightness detection jig.

Background

In the prior art, a liquid transfer device adopts piston type suction and works by utilizing an air discharge principle; the liquid is sucked from the pipette tip into the pipette cavity of the pipette by the discharge of air. Determining the sucking capacity of the liquid dispenser according to the moving distance of the piston in the liquid dispenser in the piston sleeve; however, during the pipetting process, due to the quality of the pipette tip itself, a complete seal cannot be formed with the tip of the pipette, which results in the pipetting liquid dripping from the suction opening of the pipette tip, which affects the final experimental result.

At present, the quality control problem is solved, the common suction head is subjected to multiple operations, after the liquid is sucked by using the liquid suction device, the liquid suction head is suspended and kept still for 3 seconds, and whether the liquid drops at the suction port of the liquid suction head are observed to directly test the matching performance. However, for an automated tip, if the function is to be verified, it is necessary to go to an automated facility for actual testing. Because the equipment is mostly in a closed structure, the liquid condition is not easy to be observed semi-automatically.

Disclosure of Invention

The utility model aims to provide a pipetting tip tightness detection jig.

The utility model provides a pipetting head tightness detection jig which comprises a rack, a limiting plate and one or more detection modules, wherein the rack is provided with a plurality of detection modules; the rack is provided with detection positions corresponding to the number of the detection modules; the detection module comprises a supporting plate, a pipette gun head, a piston cylinder, a piston, a connecting rod and a driving handle; the supporting plate is fixed on the frame; the pipette gun head and the piston cylinder which are communicated with the inner cavity are fixed with the supporting plate; the suction head mounting port of the pipette gun head faces to the right lower part; the piston is connected in the inner cavity of the piston cylinder in a sliding way; the driving handle is connected to the frame in a sliding way and is fixed with the piston through a connecting rod. The limiting plate is fixed on the frame; the driving handle is positioned between the limiting plate and the supporting plate; the limiting plate and the supporting plate respectively limit two limit positions of the driving handle.

Preferably, the jig further comprises a locking plate; the locking plate is fixed on the driving handle and can be fixed at different positions of the frame to lock the position of the driving handle.

Preferably, the frame comprises a bottom plate and a guide post; a plurality of guide posts which are vertically arranged are all fixed on the bottom plate. The backup pad sliding connection is on each guide post, and can lock in different positions. The locking plate is connected to each guide post in a sliding manner and can be locked at different positions.

Preferably, the limiting plate and the locking plate are both in a hoop structure and are locked at different positions on the guide post through bolts; the bolt adopts butterfly screw.

Preferably, the pipette tip and the piston cylinder are respectively fixed on the bottom surface and the top surface of the supporting plate; the supporting plate is provided with a gas transmission hole which is communicated with the gun head of the liquid transfer device and the piston cylinder.

Preferably, the maximum adjusting stroke of the limiting plate and the supporting plate is 20 mm-30 mm.

Preferably, the jig further comprises a top plate; the top plate is fixed at the top end of the frame; a handle is fixed on the top plate.

Preferably, the detection modules are multiple, and pipette tips in different detection modules respectively correspond to different types of pipette tips.

Preferably, the jig further comprises a water storage box; the water storage box is used for moving to the lower part of the pipette gun head so as to suck liquid by the measured pipette tip.

Preferably, the bottom plate is fixed on the top of the supporting frame; the bottom plate is provided with first abdication through grooves corresponding to the number of the detection modules; the first abdication through groove is positioned right below the pipette tip in the corresponding detection module.

The utility model has the beneficial effects that:

1. according to the utility model, the measured liquid-transfering suction head is arranged on the liquid-transfering device gun head corresponding to the specification detection position, and the dripping condition of the measured liquid-transfering suction head at the suction port of the liquid-transfering suction head when the liquid with different capacities is sucked is observed; the staff can intuitively detect the sealing condition when the liquid is sucked when the detected liquid-transfering sucker works.

2. According to the utility model, the locking plate and the limiting plate are arranged to limit the sliding travel of the driving handle, so that when the pipette tips with the same specification are detected, the liquid amount sucked by each pipette tip is the same; thereby avoiding error of detection results caused by different sucked liquid amounts.

Drawings

FIG. 1 is a schematic diagram of the overall structure of the present utility model;

FIG. 2 is a schematic diagram showing the relative positions of the detection module and the base plate according to the present utility model;

FIG. 3 is a side cross-sectional view (cross-sectional view in the direction A-A in FIG. 2) of the present utility model;

fig. 4 is a schematic structural diagram of a detection module according to the present utility model (a partial enlarged view of B in fig. 3).

Wherein, 1, the frame; 1-1, a bottom plate; 1-2, a guide post; 2. a support frame; 3. a water storage box; 4. a detection module; 4-1, a supporting plate; 4-2, a pipette tip; 4-3, a piston cylinder; 4-4, a piston; 4-5, connecting rod; 4-6, driving a handle; 4-7, locking plate; 5. a limit locking module; 5-1, limiting plates; 5-2, butterfly screws; 6. the pipette tip is tested.

Detailed Description

The utility model is further described below with reference to the accompanying drawings.

Example 1

As shown in fig. 1 and 2, a pipette tip tightness detection jig comprises a frame 1, a limit locking module 5, a top plate, a water storage box 3 and two support frames 2. The frame 1 comprises a bottom plate 1-1 and a plurality of guide posts 1-2 which are vertically arranged. The bottom ends of the guide posts 1-2 are fixed with the bottom plate 1-1. Two detection bits are arranged on the bottom plate 1-1. The first detection site is used to detect hamilton tips. The second detection site is used to detect a tecan tip. The detection bit is provided with a detection module 4. The detection position on the bottom plate 1-1 is provided with a first yielding through groove which is U-shaped and is positioned below the corresponding detection module 4. The top plate is fixed with the top end of the guide post 1-2. The upper surface of the top plate is fixed with a handle. The handle is convenient for the detection jig to be held; and moving the placement position of the detection jig. The top edges of the two supporting frames 2 are fixed with the two side edges of the lower surface of the bottom plate 1-1. The water storage box 3 is placed between the two support frames 2. The two opposite inner walls of the water storage box 3 are provided with second yielding through grooves; the second abdication through groove is U-shaped. A second yielding through groove is formed in the water storage box 3, so that the water storage box 3 can be removed conveniently after the liquid is sucked by the liquid-transfering sucker 6 to be tested.

As shown in fig. 3 and 4, the detection module 4 includes a support plate 4-1, a pipette tip 4-2, a piston cylinder 4-3, a piston 4-4, a connecting rod 4-5, a drive handle 4-6, and a lock plate 4-7. The supporting plate 4-1 is connected to each guide post 1-2 in a sliding way; and can be locked and fixed at different positions of the guide post 1-2 through the set screw. The pipette tip 4-2 and the piston cylinder 4-3 are fixed to the bottom surface and the top surface of the support plate 4-1, respectively. The supporting plate 4-1 is provided with a gas transmission hole which is communicated with the inner cavity of the pipette tip 4-2 and the inner cavity of the piston cylinder 4-3.

The piston 4-4 is slidably connected within the interior chamber of the piston cylinder 4-3. The driving handle 4-6 is connected on the guide post 1-2 in a sliding way. The piston 4-4 and the driving handle 4-6 are connected through a connecting rod 4-5. The locking plate 4-7 is fixed to the driving handle 4-6. The locking plates 4-7 are all of hoop structures, and are locked at different positions on the guide post 1-2 through the butterfly screws 5-2, so that the position of the driving handle 4-6 on the guide post 1-2 is locked. During detection, the detected pipetting head 6 is installed and fixed on the pipette gun head 4-2, and the tip suction port of the detected pipetting head 6 passes through the first yielding through groove and stretches into the water storage box 3. Pushing the driving handle 4-6 upwards so that the piston 4-4 in the piston cylinder 4-3 slides upwards; the pipetting head 6 to be measured sucks water in the water storage box 3. After the liquid is sucked by the detected pipetting tip 6, the water storage box 3 is removed, and a worker can intuitively observe whether the liquid drops at the suction opening of the detected pipetting tip 6, so as to judge whether the tightness of the detected pipetting tip 6 meets the requirement.

As shown in fig. 1, the limit lock module 5 includes a limit plate 5-1 and a butterfly screw 5-2. The limiting plate 5-1 adopts a hoop structure. The limiting plate 5-1 can be slidably adjusted along the axial direction of the guide post 1-2 and is positioned right above the driving handle 4-6. The limiting plate 5-1 is locked on the guide post 1-2 through the butterfly screw 5-2. The limiting plate 5-1 and the supporting plate 4-1 respectively define two extreme positions of the driving handle 4-6. The maximum adjusting stroke of the limiting plate 5-1 and the supporting plate 4-1 is 20 mm-30 mm. Wherein the stroke is the distance that the drive handle 4-6 moves from the lower extreme position to the upper extreme position. When the spacing between the limiting plate 5-1 and the supporting plate 4-1 is adjusted to correspond to the detection specification of the corresponding pipetting head 6 to be detected, the limiting plate 5-1 is locked and fixed by rotating the butterfly screw 5-2. The limiting plate 5-1 is arranged to be convenient for limiting the upper limit position of the driving handle 4-6, so that when the detected pipetting tips 6 with the same specification are detected, the liquid amount sucked by each detected pipetting tip 6 is the same, and detection errors are avoided.

The working flow of the utility model is as follows:

the limiting plate 5-1 is slidingly adjusted along the axial direction of the guide post 1-2; when the spacing plate 5-1 and the support plate 4-1 are adjusted to a specified distance, the spacing plate 5-1 is locked on the guide post 1-2 by turning the butterfly screw 5-2. The pipette tip 6 to be measured is installed and fixed on the pipette gun head 4-2, and the tip suction port of the pipette tip 6 to be measured passes through the first abdication through groove; the water storage box 3 is lifted upwards, so that the tip suction port of the pipetting tip 6 to be tested is immersed in the liquid in the water storage box 3. Pushing the driving handle 4-6 upwards so that the piston 4-4 in the piston cylinder 4-3 slides upwards; the pipetting head 6 to be measured sucks water in the water storage box 3. After the suction is finished, the driving handle 4-6 is locked on the guide post 1-2 through the butterfly screw 5-2.

Taking down the water storage box 3; so that the detected pipetting head 6 is suspended and kept stand for a preset time (more than or equal to 3 seconds) to observe whether the liquid drops at the suction port of the pipetting head.

Claims

1. A pipetting tip tightness detection jig comprises a frame (1), a limit locking module (5) and one or more detection modules (4); the method is characterized in that: the frame (1) is provided with detection positions corresponding to the detection modules (4); the detection module (4) comprises a supporting plate (4-1), a pipette gun head (4-2), a piston cylinder (4-3), a piston (4-4), a connecting rod (4-5) and a driving handle (4-6); the supporting plate (4-1) is fixed on the frame (1); the pipette gun head (4-2) and the piston cylinder (4-3) which are communicated with the inner cavity are fixed with the supporting plate (4-1); the suction head mounting port of the pipette gun head (4-2) faces to the right lower part; the piston (4-4) is connected in the inner cavity of the piston cylinder (4-3) in a sliding way; the driving handle (4-6) is connected to the frame (1) in a sliding way and is fixed with the piston (4-4) through the connecting rod (4-5); the limit locking module comprises a limit plate (5-1); the limiting plate (5-1) is fixed on the frame (1); the driving handle (4-6) is positioned between the limiting plate (5-1) and the supporting plate (4-1); the limiting plate (5-1) and the supporting plate (4-1) respectively limit two limit positions of the driving handle (4-6).

2. The pipette tip tightness detection jig according to claim 1, wherein: also comprises a locking plate (4-7); the locking plate (4-7) is fixed on the driving handle (4-6) and can be fixed at different positions of the frame (1) to lock the position of the driving handle (4-6).

3. The pipette tip tightness detection jig according to claim 2, wherein: the frame (1) comprises a bottom plate (1-1) and a guide column (1-2); a plurality of guide posts (1-2) which are vertically arranged are fixed on the bottom plate (1-1); the supporting plate (4-1) is connected to each guide post (1-2) in a sliding way and can be locked at different positions; the locking plates (4-7) are slidably connected to the respective guide posts (1-2) and can be locked in different positions.

4. A pipette tip tightness test fixture as defined in claim 3, wherein: the limiting plate (5-1) and the locking plate (4-7) are of hoop structures and are locked at different positions on the guide post (1-2) through bolts; the bolt adopts a butterfly screw (5-3).

5. The pipette tip tightness detection jig according to claim 1, wherein: the pipette gun head (4-2) and the piston cylinder (4-3) are respectively fixed on the bottom surface and the top surface of the supporting plate (4-1); the supporting plate (4-1) is provided with a gas transmission hole which is communicated with the pipette tip (4-2) and the piston cylinder (4-3).

6. The pipette tip tightness detection jig according to claim 1, wherein: the maximum adjusting stroke of the limiting plate (5-1) and the supporting plate (4-1) is 20 mm-30 mm.

7. The pipette tip tightness detection jig according to claim 1, wherein: the device also comprises a top plate; the top plate is fixed at the top end of the frame (1); a handle is fixed on the top plate.

8. The pipette tip tightness detection jig according to claim 1, wherein: the detection modules (4) are in common, and pipette tips (4-2) in different detection modules (4) respectively correspond to different types of pipette tips.

9. The pipette tip tightness detection jig according to claim 1, wherein: the water storage box (3) is also included; the water storage box (3) is used for moving to the lower part of the pipette gun head (4-2) so as to suck liquid by the measured pipette tip.

10. A pipette tip tightness test fixture as defined in claim 3, wherein: the bottom plate (1-1) is fixed at the top of the supporting frame (2-1); the bottom plate (1-1) is provided with first yielding through grooves corresponding to the detection modules (4); the first abdication through groove is positioned right below the pipette tip (4-2) in the corresponding detection module (4).