CN220643134U - Umbilical cord blood stem cell separation detection device - Google Patents
Umbilical cord blood stem cell separation detection device Download PDFInfo
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- CN220643134U CN220643134U CN202322222833.XU CN202322222833U CN220643134U CN 220643134 U CN220643134 U CN 220643134U CN 202322222833 U CN202322222833 U CN 202322222833U CN 220643134 U CN220643134 U CN 220643134U
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- umbilical cord
- cord blood
- temperature heating
- stem cell
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- 210000004700 fetal blood Anatomy 0.000 title claims abstract description 40
- 238000000926 separation method Methods 0.000 title claims abstract description 40
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 31
- 238000001514 detection method Methods 0.000 title claims abstract description 28
- 238000010438 heat treatment Methods 0.000 claims abstract description 40
- 238000002791 soaking Methods 0.000 claims abstract description 11
- 230000001133 acceleration Effects 0.000 claims abstract description 9
- 230000000149 penetrating effect Effects 0.000 claims abstract description 9
- 239000007788 liquid Substances 0.000 claims description 15
- 238000012423 maintenance Methods 0.000 claims description 7
- 230000003993 interaction Effects 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 abstract description 15
- 239000008280 blood Substances 0.000 abstract description 15
- 238000004090 dissolution Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 2
- 235000017491 Bambusa tulda Nutrition 0.000 description 2
- 241001330002 Bambuseae Species 0.000 description 2
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000011425 bamboo Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 208000032467 Aplastic anaemia Diseases 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 208000024340 acute graft versus host disease Diseases 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011476 stem cell transplantation Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
- External Artificial Organs (AREA)
Abstract
The utility model discloses an umbilical cord blood stem cell separation detection device, which comprises: a body assembly; an acceleration assembly; the accelerating assembly comprises an anchor ear, a fastening bolt, a movable groove, two groups of sliding blocks, springs, a constant-temperature heating plate, a control line, a soaking plate, a pipe penetrating groove, telescopic rods and two groups of angular points, wherein the fastening bolt is used for locking the anchor ear, the movable groove is formed in the front side of the anchor ear, the two groups of sliding blocks are movably connected in the movable groove, the springs are connected between the sliding blocks, the constant-temperature heating plate is connected to the front end of the sliding blocks, the control line is connected to the rear side of the constant-temperature heating plate, the soaking plate is connected to the inner side of the constant-temperature heating plate, the pipe penetrating groove is formed in the lower end of the constant-temperature heating plate, the telescopic rods are connected to the lower ends of the two groups of constant-temperature heating plates, and the telescopic rods are respectively connected to the two angular points at the lower ends of the constant-temperature heating plate; and (5) maintaining the assembly. Through the acceleration subassembly and the main part subassembly mutually supporting that set up use, increase the constant temperature hot plate on centrifugal separation equipment support, dissolve the blood bag, the umbilical cord blood synchronization input centrifuge after dissolving has greatly improved separation efficiency, has reduced the probability that takes place to pollute and reveal in the transportation.
Description
Technical Field
The utility model relates to the technical field of cell separation detection devices, in particular to a device for separating and detecting umbilical cord blood stem cells.
Background
The umbilical cord blood is blood in the umbilical cord and blood vessels near the fetus at birth, contains a large amount of stem cells, has weak lymphocyte antigenicity and relatively immature functions, has low risk of acute graft versus host disease after transplantation, becomes an important way for stem cell transplantation, has wide application in the treatment of malignant tumors, aplastic anemia, partial genetic diseases and the like of a blood system, and needs to be separated and detected before the umbilical cord blood stem cells are put into use, so that the comprehensive evaluation is carried out, and the use safety performance is improved.
The umbilical cord blood needs to be frozen and preserved after collection, so the umbilical cord blood needs to be placed in a 37-DEG water bath for dissolution before separation, and then is input into a centrifuge for separation after dissolution, pollution or leakage is easy to cause in the process of dissolution and transportation to the centrifuge, and on the other hand, a certain time is required in the process of dissolution, so that the whole separation and detection efficiency is too slow, and therefore, the umbilical cord blood stem cell separation and detection device is provided.
Disclosure of Invention
Therefore, the utility model aims to provide the umbilical cord blood stem cell separation detection device, the accelerating assembly and the main body assembly are mutually matched for use, the constant-temperature heating plate is added on the centrifugal separation equipment bracket to dissolve the blood bag, and the dissolved umbilical cord blood is synchronously input into the centrifugal machine, so that the separation efficiency is greatly improved, and the probability of pollution and leakage in transportation is reduced.
In order to solve the technical problems, according to one aspect of the present utility model, the following technical solutions are provided:
an umbilical cord blood stem cell separation detection device comprising:
a body assembly;
an acceleration assembly;
the accelerating assembly comprises an anchor ear, a fastening bolt, a movable groove, two groups of sliding blocks, springs, a constant-temperature heating plate, a control line, a soaking plate, a pipe penetrating groove and telescopic rods, wherein the fastening bolt is used for locking the anchor ear, the movable groove is formed in the front side of the anchor ear, the two groups of sliding blocks are movably connected in the movable groove, the springs are connected between the sliding blocks, the constant-temperature heating plate is connected to the front end of the sliding blocks, the control line is connected to the rear side of the constant-temperature heating plate, the soaking plate is connected to the inner side of the constant-temperature heating plate, the pipe penetrating groove is formed in the lower end of the constant-temperature heating plate, and the telescopic rods are connected to the lower ends of the two groups of constant-temperature heating plates;
and (5) maintaining the assembly.
As a preferable mode of the umbilical cord blood stem cell separation detection device of the present utility model, the other end of the control wire is connected with a temperature control device.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, two groups of telescopic rods are respectively connected to two corner points at the lower end of the constant-temperature heating plate.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, the main body component comprises a shell, an adjusting foot nail connected to the lower end of the shell and a man-machine interaction interface connected to the front end of the shell.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, the main body assembly further comprises a centrifugal cylinder connected to the middle position of the upper end of the shell, and a liquid inlet connected to the centrifugal cylinder.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, the main body assembly further comprises a liquid outlet connected to the side edge of the shell, and the liquid outlet is communicated with the centrifugal cylinder.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, the main body assembly further comprises a bracket connected to the rear side of the upper end of the shell, and a hanging rod rotatably connected to the top of the bracket.
Specifically, adjust the pin and make the casing keep steady, hang umbilical cord blood sample bag and separating agent bag on the peg, switch on the inlet, switch on the power, select separation mode through man-machine interaction interface, start up equipment, umbilical cord blood and separating agent flow into the centrifugation section of thick bamboo, the centrifugation section of thick bamboo begins work, stem cells after the separation and other layering liquid export different liquid outlets through the closed aseptic pipeline of the inside intercommunication of casing, flow into in different stock solution bags and the cell collection bag again.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, the anchor ear is movably connected to the bracket.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, the maintenance assembly comprises a first through hole and a second through hole which are formed in the upper surface and the lower surface of the anchor ear, and the first through hole and the second through hole are symmetrical.
As a preferable scheme of the umbilical cord blood stem cell separation detection device, the maintenance assembly further comprises an opening formed at the side edge of the movable groove and an L-shaped baffle connected in the first through hole and the second through hole.
Compared with the prior art, the utility model has the advantages that:
1. according to the utility model, the constant-temperature heating plate is connected to the bracket for hanging the blood bag, so that umbilical cord blood is dissolved and conveyed, the separation efficiency is greatly improved, and the probability of pollution and leakage in transportation is reduced.
2. Based on the first beneficial effect, the soaking plate connected to the inner side of the constant temperature heating plate can make the blood bag heated uniformly.
3. Based on beneficial effect one, the connected mode of staple bolt formula, the dismouting of being convenient for is applicable to the support of different specifications.
When the device is specifically used, the anchor ear is locked at a proper height on the support by the fastening bolt, the blood bag is placed between the two constant temperature heating plates, the sliding block moves and clamps in the middle of the constant temperature heating plates under the action of the spring and the telescopic rod, the blood bag is clamped in the middle of the constant temperature heating plates, the lower part of the blood bag passes through the tube penetrating groove and is connected to the liquid inlet, the control line is connected, the temperature of the constant temperature heating plates is regulated by the temperature control equipment connected with the control line, the constant temperature heating plates start to work at about 37 ℃, the generated heat enables the soaking plates to be heated uniformly, and umbilical cord blood in the blood bag is dissolved gradually.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the following detailed description of the embodiments of the present utility model will be given with reference to the accompanying drawings, which are to be understood as merely some embodiments of the present utility model, and from which other drawings can be obtained by those skilled in the art without inventive faculty. Wherein:
FIG. 1 is a block diagram of the present utility model;
FIG. 2 is a block diagram of an acceleration assembly of the present utility model;
FIG. 3 is a block diagram of a service assembly of the present utility model.
In the figure: 10. a body assembly; 11. a hanging rod; 12. a bracket; 13. a housing; 14. a centrifugal barrel; 15. a liquid inlet; 16. a human-computer interaction interface; 17. a liquid outlet; 18. adjusting the foot nails; 20. an acceleration assembly; 21. a hoop; 22. a fastening bolt; 23. a movable groove; 24. a slide block; 25. a spring; 26. a constant temperature heating plate; 260. a pipe penetrating groove; 27. a control line; 28. a soaking plate; 29. a telescopic rod; 30. maintaining the assembly; 31. an L-shaped baffle; 32. a first through hole; 33. opening holes; 34. and a second through hole.
Detailed Description
In order that the above objects, features and advantages of the utility model will be readily understood, a more particular description of the utility model will be rendered by reference to the appended drawings.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present utility model, but the present utility model may be practiced in other ways other than those described herein, and persons skilled in the art will readily appreciate that the present utility model is not limited to the specific embodiments disclosed below.
In the following detailed description of the embodiments of the present utility model, the cross-sectional view of the device structure is not partially enlarged to a general scale for the convenience of description, and the schematic is merely an example, which should not limit the scope of the present utility model. In addition, the three-dimensional dimensions of length, width and depth should be included in actual fabrication.
For the purpose of making the objects, technical solutions and advantages of the present utility model more apparent, embodiments of the present utility model will be described in further detail below with reference to the accompanying drawings.
The utility model provides an umbilical cord blood stem cell separation detection device: through the acceleration subassembly and the main part subassembly mutually supporting that set up use, increase the constant temperature hot plate on centrifugal separation equipment support, dissolve the blood bag, the umbilical cord blood synchronization input centrifuge after dissolving has greatly improved separation efficiency, has reduced the probability that takes place to pollute and reveal in the transportation.
Example 1
FIGS. 1-2 are schematic views showing the overall structure of an embodiment of the cord blood stem cell separation detection apparatus of the present utility model, comprising: a body assembly 10 and an acceleration assembly 20.
The main body assembly 10 comprises a shell 13, an adjusting foot nail 18 connected to the lower end of the shell 13, a man-machine interaction interface 16 connected to the front end of the shell 13, a centrifugal barrel 14 connected to the middle position of the upper end of the shell 13, a liquid inlet 15 connected to the centrifugal barrel 14, a liquid outlet 17 connected to the side edge of the shell 13, a bracket 12 connected to the rear side of the upper end of the shell 13, and a hanging rod 11 rotatably connected to the top of the bracket 12, wherein the liquid outlet 17 is communicated with the centrifugal barrel 14;
the accelerating assembly 20 comprises a hoop 21, a fastening bolt 22, a movable groove 23, two groups of sliding blocks 24, springs 25, a constant-temperature heating plate 26, a control line 27, a temperature control device, a soaking plate 28, a pipe penetrating groove 260, a telescopic rod 29 and two groups of angular points, wherein the hoop 21 is movably connected to the bracket 12, the fastening bolt 22 is used for locking the hoop 21, the movable groove 23 is formed in the front side of the hoop 21, the two groups of sliding blocks 24 are movably connected in the movable groove 23, the springs 25 are connected between the sliding blocks 24, the constant-temperature heating plate 26 is connected to the front end of the sliding blocks 24, the control line 27 is connected to the rear side of the constant-temperature heating plate 26, the other end of the control line 27 is connected with the temperature control device, the soaking plate 28 is connected to the inner side of the constant-temperature heating plate 26, and the telescopic rod 29 is connected to the lower ends of the two groups of the constant-temperature heating plate 26.
Use of acceleration assembly 20:
the anchor ear 21 is locked at a proper height on the support 12 by the fastening bolt 22, a blood bag is placed between the two constant temperature heating plates 26, the sliding block 24 moves and clamps in the movable groove 23 under the action of the spring 25 and the telescopic rod 29, the blood bag is clamped between the constant temperature heating plates 26, the lower part of the blood bag passes through the pipe penetrating groove 260 and is communicated with the liquid inlet 15, the control line 27 is communicated, the temperature control equipment connected with the outside of the control line 27 regulates the temperature of the constant temperature heating plates 26 to be about 37 ℃, the constant temperature heating plates 26 start to work, the generated heat enables the soaking plates 28 to be heated uniformly, and umbilical cord blood in the blood bag is dissolved gradually.
Example 2
This embodiment further includes a maintenance assembly 30 on the basis of embodiment 1, as shown in fig. 3:
the maintenance assembly 30 comprises a first through hole 32 and a second through hole 34 which are formed in the upper surface and the lower surface of the anchor ear 21, the first through hole 32 and the second through hole 34 are symmetrical in position, an opening 33 which is formed in the side edge of the movable groove 23, and an L-shaped baffle 31 which is connected in the first through hole 32 and the second through hole 34.
Use of the maintenance assembly 30:
the constant temperature heating plate 26 is easy to damage after long-term use, and the elasticity of the spring 25 also disappears along with time, at this time, the L-shaped baffle 31 can be taken out from the first through hole 32 and the second through hole 34, the sliding block 24 can slide out from the opening 33, and the constant temperature heating plate 26 and other related accessories can be maintained and replaced.
Although the utility model has been described hereinabove with reference to embodiments, various modifications thereof may be made and equivalents may be substituted for elements thereof without departing from the scope of the utility model. In particular, the features of the disclosed embodiments may be combined with each other in any manner as long as there is no structural conflict, and the exhaustive description of these combinations is not given in this specification merely for the sake of omitting the descriptions and saving resources. Therefore, it is intended that the utility model not be limited to the particular embodiment disclosed, but that the utility model will include all embodiments falling within the scope of the appended claims.
Claims (10)
1. The umbilical cord blood stem cell separation detection device is characterized by comprising:
a body assembly (10);
an acceleration assembly (20);
the accelerating assembly (20) comprises an anchor ear (21), a fastening bolt (22) for locking the anchor ear (21), a movable groove (23) formed in the front side of the anchor ear (21), two groups of sliding blocks (24) movably connected in the movable groove (23), springs (25) connected between the sliding blocks (24), a constant-temperature heating plate (26) connected at the front end of the sliding blocks (24), a control wire (27) connected at the rear side of the constant-temperature heating plate (26), a soaking plate (28) connected at the inner side of the constant-temperature heating plate (26), a pipe penetrating groove (260) formed in the lower end of the constant-temperature heating plate (26) and a telescopic rod (29) connected at the lower ends of the two groups of constant-temperature heating plates (26);
a service assembly (30).
2. The umbilical cord blood stem cell separation detection apparatus as claimed in claim 1, wherein the other end of the control line (27) is connected with a temperature control device.
3. The umbilical cord blood stem cell separation detection apparatus as claimed in claim 1, wherein the telescopic rods (29) are connected at two corner points at the lower end of the constant temperature heating plate (26) in total.
4. The umbilical cord blood stem cell separation detection device according to claim 1, wherein the main body assembly (10) comprises a shell (13) arranged, an adjusting foot nail (18) connected to the lower end of the shell (13), and a man-machine interaction interface (16) connected to the front end of the shell (13).
5. The umbilical cord blood stem cell separation detection apparatus as claimed in claim 4, wherein the body assembly (10) further comprises a centrifuge tube (14) connected to an upper end intermediate position of the housing (13), and a liquid inlet (15) connected to the centrifuge tube (14).
6. The umbilical cord blood stem cell separation detection apparatus as claimed in claim 5, wherein the body assembly (10) further comprises a liquid outlet (17) connected to a side of the housing (13), and the liquid outlet (17) is in communication with the centrifuge tube (14).
7. The umbilical cord blood stem cell separation detecting apparatus as claimed in claim 6, wherein the main body assembly (10) further comprises a bracket (12) connected to the rear side of the upper end of the housing (13), and a hanging rod (11) rotatably connected to the top of the bracket (12).
8. The umbilical cord blood stem cell separation detection apparatus as claimed in claim 7, wherein the anchor ear (21) is movably connected to the bracket (12).
9. The umbilical cord blood stem cell separation detection device according to claim 1, wherein the maintenance assembly (30) comprises a first through hole (32) and a second through hole (34) which are formed in the upper surface and the lower surface of the anchor ear (21), and the first through hole (32) and the second through hole (34) are symmetrical in position.
10. The umbilical cord blood stem cell separation detection apparatus as claimed in claim 1, wherein the maintenance assembly (30) further comprises an opening (33) opened at a side of the movable groove (23), and an L-shaped baffle (31) connected in the first through hole (32) and the second through hole (34).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322222833.XU CN220643134U (en) | 2023-08-17 | 2023-08-17 | Umbilical cord blood stem cell separation detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322222833.XU CN220643134U (en) | 2023-08-17 | 2023-08-17 | Umbilical cord blood stem cell separation detection device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220643134U true CN220643134U (en) | 2024-03-22 |
Family
ID=90296550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322222833.XU Active CN220643134U (en) | 2023-08-17 | 2023-08-17 | Umbilical cord blood stem cell separation detection device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220643134U (en) |
-
2023
- 2023-08-17 CN CN202322222833.XU patent/CN220643134U/en active Active
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