CN220603035U - Semisolid preparation sampling device - Google Patents

Semisolid preparation sampling device Download PDF

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Publication number
CN220603035U
CN220603035U CN202321593177.8U CN202321593177U CN220603035U CN 220603035 U CN220603035 U CN 220603035U CN 202321593177 U CN202321593177 U CN 202321593177U CN 220603035 U CN220603035 U CN 220603035U
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China
Prior art keywords
sleeve
end cap
piston
rear end
sampling device
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CN202321593177.8U
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Chinese (zh)
Inventor
王钰
黄域
陈怡�
蔡吟天
任略
张晓敏
叶宝婷
梁贤临
汪竹群
姜树红
刘春晖
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Wuxi STA Pharmaceutical Co Ltd
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Wuxi STA Pharmaceutical Co Ltd
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Priority to CN202321593177.8U priority Critical patent/CN220603035U/en
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Abstract

The utility model discloses a semisolid preparation sampling device which comprises a sleeve, a rear end cap and a front end cap, wherein the sleeve is arranged at the top end and the bottom end of the sleeve in an open mode, the rear end cap and the front end cap are respectively detachably arranged at the top end and the bottom end of the sleeve, scale marks are arranged on the outer wall of the sleeve, a piston assembly is arranged in the sleeve, and central shafts of the sleeve, the front end cap and the rear end cap are coaxially arranged. According to the utility model, the front end cap is arranged, so that the influence of a surface layer sample on the deep sampling can be effectively avoided; the outer surface of the sleeve is provided with scale marks so that an operator can accurately extract samples with different depths according to requirements; the sleeve, the front end cap and the rear end cap are detachably connected, so that all parts can be conveniently cleaned and stored before and after sampling; the semisolid preparation sampling device provided by the utility model has the advantages of simple structure, convenience in assembly, convenience in accurate deep sampling and convenience in cleaning and storage, and is suitable for sampling semisolid preparations.

Description

Semisolid preparation sampling device
Technical Field
The utility model relates to the field of pharmacy, in particular to a semisolid preparation sampling device.
Background
In the pharmaceutical field, for solid preparations, sampling operation is required to be performed on the mixture before tabletting or filling operation, and whether the active medicine and the auxiliary materials are uniformly mixed is judged; for semi-solid formulations, sampling the mixture prior to filling is highly desirable because of the unique material characteristics and the risk of non-uniform mixing throughout the filling equipment, which can ultimately lead to unacceptable filled products.
For example, chinese patent discloses a semisolid or pasty viscous liquid sampler (patent number: CN 211122113U), which comprises a sampling tube, a piston rod and a piston, wherein two ends of the sampling tube are open, the piston rod is arranged in the sampling tube, the piston rod is in threaded connection with the sampling tube, and the piston is arranged at the end part of the piston rod. When the sampler samples, the piston rod is screwed out upwards for a certain distance relative to the sampling tube, and then the sampling tube is inserted into the sample for sampling. The patent can carry out the degree of depth sample to the sample, and can not lead to the sample to confuse, easy operation, labour saving and time saving. However, the above patent cannot accurately take out samples of different heights or positions although the sampling port is open, and the samples taken out have mixed surface layers, which may cause inaccuracy in detection.
Disclosure of Invention
The utility model aims to solve the technical problem of providing a semisolid preparation sampling device, which can accurately obtain samples with different depths, and the surface samples do not pollute the samples taken out at the different depths, and is convenient to clean and store.
In order to solve the above technical problems, the semisolid preparation sampling device provided by the utility model comprises:
the top end and the bottom end of the sleeve are both open, and the outer wall of the sleeve is provided with scale marks for measuring the depth of the semisolid preparation;
the front end cover cap is detachably arranged at the bottom end of the sleeve, and is provided with a material port for the entrance and the discharge of the semisolid preparation;
the rear end cover cap is detachably arranged at the top end of the sleeve;
a piston assembly disposed within the sleeve;
the sleeve, the front end cap and the rear end cap are coaxially arranged on a central shaft.
Preferably, the piston assembly comprises a piston and a piston rod which are detachably connected, and the end of the piston rod, which is far away from the piston, is provided with a holding part.
Preferably, the piston and the piston rod are threadedly connected.
Preferably, the front end cap is in threaded connection with the sleeve.
Preferably, the rear end cap is in threaded connection with the sleeve.
Preferably, an end cover is formed at one end of the rear end cap, a through hole is formed in the end cover for the piston rod to penetrate, and the through hole and the rear end cap are coaxially arranged.
Preferably, the sleeve outer wall is located at the top end position to form a force assisting arm.
Preferably, the sleeve, the front end cap and the rear end cap are all made of stainless steel.
Preferably, the piston rod is made of stainless steel, and the piston is made of polytetrafluoroethylene.
According to the utility model, the front end cap is arranged, so that the influence of a surface layer sample on the deep sampling can be effectively avoided; the outer surface of the sleeve is provided with scale marks so that an operator can accurately extract samples with different depths according to requirements; the sleeve, the front end cap and the rear end cap are detachably connected, so that all parts can be conveniently cleaned and stored before and after sampling; the semisolid preparation sampling device provided by the utility model has the advantages of simple structure, convenience in assembly, convenience in accurate deep sampling and convenience in cleaning and storage, and is suitable for sampling semisolid preparations.
Drawings
In order to more clearly illustrate the technical solutions of the present utility model, the following brief description of the drawings is given for the purpose of the present utility model, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and that other drawings can be obtained according to these drawings without the need for inventive work for a person skilled in the art.
FIG. 1 is a schematic diagram of a semisolid preparation sampling device according to one embodiment of the present utility model;
FIG. 2 is a schematic diagram showing the connection of a piston assembly of an embodiment of a semisolid preparation sampling device of the present utility model;
in the figure, 1-sleeve; 2-front end cap; 21-material port; 3-rear end cap; 31-end caps; 32-through holes; 4-a piston assembly; 41-a piston; 42-a piston rod; 43-grip.
Detailed Description
The following description of the embodiments of the present utility model will be made more apparent and fully hereinafter with reference to the accompanying drawings, in which some, but not all embodiments of the utility model are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1, there is shown a semisolid formulation sampling device of the present utility model, comprising:
the top end and the bottom end of the sleeve are both open, and the outer wall of the sleeve is provided with scale marks for measuring the depth of the semisolid preparation;
the front end cover cap is detachably arranged at the bottom end of the sleeve, and is provided with a material port for the entrance and the discharge of the semisolid preparation;
the rear end cover cap is detachably arranged at the top end of the sleeve;
a piston assembly disposed within the sleeve;
the sleeve, the front end cap and the rear end cap are coaxially arranged on a central shaft.
In the embodiment of the utility model, the sleeve is in a straight cylinder shape with two open ends, the two ends of the sleeve are respectively connected with the front end cap and the rear end cap in a detachable manner, and the piston assembly is arranged in the sleeve and is used for extracting or releasing the semisolid preparation; the outer wall of the sleeve is provided with scale marks, so that an operator can accurately extract samples with different depths according to requirements; the front end cover cap is mainly used for preventing a surface layer sample from entering the sleeve to affect the sample at the sampling position when deep sampling is performed, and the front end cover cap is provided with a material port, so that the amount of the surface layer sample carried by the material port when the material port passes through the surface layer of the sample is small relative to the amount of the sample required by detection, the detection of the sample is hardly affected, the detection is negligible, and the caliber of the material port can be properly adjusted according to the viscosity of a semi-fixed preparation; the sleeve, the front end cap and the rear end cap are detachable, so that the sleeve, the front end cap and the rear end cap are convenient to clean and store independently; the sleeve, the front end cap and the rear end cap are coaxially arranged to facilitate sampling.
In a specific embodiment, the piston assembly comprises a piston and a piston rod which are detachably connected, the end of the piston rod remote from the piston to which the piston is connected being provided with a grip. Understandably, the detachable arrangement of the piston and the piston rod also facilitates cleaning and storage of the components to some extent; the grip part is arranged on the piston rod to facilitate sampling and releasing samples.
In a specific embodiment, the piston and the piston rod are threadedly connected (see fig. 2); the front end cap is in threaded connection with the sleeve; the rear end cap is in threaded connection with the sleeve. In the specific embodiment, a blind hole is formed at the connecting position of the piston and the piston rod, an internal thread is formed on the hole wall of the blind hole, an external thread is formed at the connecting position of the piston rod and the piston, and the two are connected through the matching of the internal thread and the external thread; the connection of the front end cap, the rear end cap and the sleeve is realized in a similar way, for example, in fig. 1, the top end and the bottom end of the sleeve are provided with external threads, the front end cap and the rear end cap are provided with internal threads, and the installation of the front end cap, the rear end cap and the sleeve is realized through threaded fit; in addition, the top end and the bottom end of the sleeve are provided with internal threads, and the front end cap and the rear end cap are provided with external threads; without wishing to be limited by this embodiment, the detachable connection between the aforementioned components may also be a snap connection or the like.
In a specific embodiment, an end cover is formed at one end of the rear end cap, a through hole is formed in the end cover for the piston rod to penetrate, and the through hole and the rear end cap are coaxially arranged. It is understood that the rear end cap with the through hole formed in the end cap is actually formed into a semi-closed structure, the size of the through hole is usually slightly larger than that of the piston rod but smaller than that of the piston, the piston rod can move freely but is limited by the wall (or edge) of the through hole, the semi-closed rear end cap can well place the falling of the piston and the piston rod, and meanwhile, the radial movable range of the piston rod is limited, so that the stability of connection between the piston and the piston rod is facilitated.
In a specific embodiment, the sleeve outer wall is located at the top end position to form a force assist arm. It will be appreciated that semi-solid formulations typically have a consistency and that the arms are provided to facilitate the extraction of a sample. In this embodiment, the semi-solid formulation sampler is used as follows: taking out all the cleaned and dried components, assembling a piston rod with a piston after penetrating through a through hole of a rear end cap, plugging the assembled piston assembly into a sleeve until the piston is positioned at an initial position of a sleeve mark, assembling the rear end cap with the top end of the sleeve, finally assembling a front end cap at the bottom end of the sleeve, after the assembly is completed, penetrating a sampler into a semisolid preparation, according to the prompt of a scale mark on the outer wall of the sleeve, extracting a sample, after the extraction is completed, taking out the sampler, and extruding the extracted sample to sample testing equipment to test the sample.
In a specific embodiment, the sleeve, the front end cap and the rear end cap are all made of stainless steel; the piston rod is made of stainless steel, and the piston is made of polytetrafluoroethylene. It is understood that the choice of the materials of each component needs to fully consider the stability of physical and chemical properties and whether the components are easy to clean, and the stainless steel materials and polytetrafluoroethylene are common materials in the field, and the materials are stable in physical and chemical properties and easy to clean.
In summary, the front end cap is arranged, so that the influence of the surface layer sample on the deep sampling can be effectively avoided; the outer surface of the sleeve is provided with scale marks so that an operator can accurately extract samples with different depths according to requirements; the sleeve, the front end cap and the rear end cap are detachably connected, so that all parts can be conveniently cleaned and stored before and after sampling; the semisolid preparation sampling device provided by the utility model has the advantages of simple structure, convenience in assembly, convenience in accurate deep sampling and convenience in cleaning and storage, and is suitable for sampling semisolid preparations.
The foregoing description of the preferred embodiments of the utility model is not intended to limit the scope of the utility model, but rather to cover any modifications, equivalents, improvements or the like within the spirit and scope of the present utility model.

Claims (9)

1. A semisolid formulation sampling device, comprising:
the top end and the bottom end of the sleeve are both open, and the outer wall of the sleeve is provided with scale marks for measuring the depth of the semisolid preparation;
the front end cover cap is detachably arranged at the bottom end of the sleeve, and is provided with a material port for the entrance and the discharge of the semisolid preparation;
the rear end cover cap is detachably arranged at the top end of the sleeve;
a piston assembly disposed within the sleeve;
the sleeve, the front end cap and the rear end cap are coaxially arranged on a central shaft.
2. The semisolid formulation sampling device according to claim 1, wherein the piston assembly comprises a piston and a piston rod detachably connected, the end of the piston rod remote from the piston to which the piston is connected being provided with a grip.
3. The semisolid formulation sampling device according to claim 1, wherein the piston and the piston rod are threadably connected.
4. The semisolid formulation sampling device according to claim 1, wherein the front end cap is threadably connected to the sleeve.
5. The semisolid formulation sampling device according to claim 1, wherein the rear end cap is threadably connected to the sleeve.
6. The semisolid formulation sampling device according to claim 2, wherein an end cap is formed at one end of the rear end cap, the end cap being provided with a through hole for the piston rod to pass through, the through hole being coaxially disposed with the rear end cap.
7. The semisolid formulation sampling device according to claim 1, wherein the outer wall of the sleeve defines a force assist arm at the top end position.
8. The semisolid formulation sampling device according to claim 1, wherein the sleeve, the front end cap and the rear end cap are all stainless steel.
9. The semisolid preparation sampling device according to claim 2, wherein the piston rod is made of stainless steel, and the piston is made of polytetrafluoroethylene.
CN202321593177.8U 2023-06-21 2023-06-21 Semisolid preparation sampling device Active CN220603035U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202321593177.8U CN220603035U (en) 2023-06-21 2023-06-21 Semisolid preparation sampling device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202321593177.8U CN220603035U (en) 2023-06-21 2023-06-21 Semisolid preparation sampling device

Publications (1)

Publication Number Publication Date
CN220603035U true CN220603035U (en) 2024-03-15

Family

ID=90171841

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202321593177.8U Active CN220603035U (en) 2023-06-21 2023-06-21 Semisolid preparation sampling device

Country Status (1)

Country Link
CN (1) CN220603035U (en)

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