CN220546586U - Powder spraying device for solid pharmaceutical auxiliary materials - Google Patents
Powder spraying device for solid pharmaceutical auxiliary materials Download PDFInfo
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- CN220546586U CN220546586U CN202321031738.5U CN202321031738U CN220546586U CN 220546586 U CN220546586 U CN 220546586U CN 202321031738 U CN202321031738 U CN 202321031738U CN 220546586 U CN220546586 U CN 220546586U
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- Prior art keywords
- powder spraying
- powder
- separator
- solid pharmaceutical
- pharmaceutical excipients
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- 239000000843 powder Substances 0.000 title claims abstract description 96
- 238000005507 spraying Methods 0.000 title claims abstract description 71
- 239000007787 solid Substances 0.000 title claims abstract description 38
- 239000000463 material Substances 0.000 title claims description 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract description 22
- 229940124531 pharmaceutical excipient Drugs 0.000 claims abstract description 21
- 239000012159 carrier gas Substances 0.000 claims abstract description 17
- 239000007789 gas Substances 0.000 claims abstract description 14
- 239000007788 liquid Substances 0.000 claims abstract description 9
- 239000002245 particle Substances 0.000 claims abstract description 7
- 230000001105 regulatory effect Effects 0.000 claims description 12
- 239000000428 dust Substances 0.000 claims description 11
- 238000007599 discharging Methods 0.000 claims description 9
- 239000008187 granular material Substances 0.000 claims description 4
- 239000011148 porous material Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 5
- 238000000034 method Methods 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 239000011344 liquid material Substances 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 238000005054 agglomeration Methods 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940098458 powder spray Drugs 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 229940126589 solid medicine Drugs 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
Landscapes
- Nozzles (AREA)
Abstract
The utility model provides a powder spraying device for solid pharmaceutical excipients, which comprises a feeding pipe, wherein a discharge hole of the feeding pipe is communicated with a powder spraying tower, the discharge hole of the powder spraying tower is provided with a flat horn-shaped nozzle with a small inside and a large outside, a gas cross flow plate is arranged in the powder spraying tower, one end of the powder spraying tower is provided with an oscillating screen, liquid enters the powder spraying tower through the feeding pipe, solid powdery particles are formed in the powder spraying tower, and the oscillating screen screens particles with different sizes. According to the utility model, by arranging the gas cross flow plate, when the carrier gas flow is changed, a certain buffer effect is provided, so that the powder flow is prevented from suddenly and greatly fluctuating when the opening of the carrier gas switch is changed, the flow stability is improved, and the powder spraying stability is further ensured.
Description
Technical Field
The utility model belongs to the technical field of solid pharmaceutical equipment, and particularly relates to a powder spraying device for solid pharmaceutical excipients.
Background
The medicine safety is about the life of everybody, so except the process is guaranteed, the raw materials for preparing the medicine are more stable and safe, wherein the pharmaceutical excipients are important raw materials, the batch-to-batch stability is particularly important, when the solid pharmaceutical excipients are used for injecting high-specification medicines such as preparations, the solid pharmaceutical excipients are subjected to strict requirements on particle size, powder spraying treatment is required, when the solid pharmaceutical excipients are subjected to powder spraying in industry, the solid pharmaceutical excipients are fed into a powder spraying tower in a liquid form, the solid pharmaceutical excipients are rapidly condensed by using cold carrier gas, solid powder is formed by adjusting the gas carrying capacity, and the solid powder is screened and fed into a finished product bin after powder spraying;
however, in the prior art, the powder spraying device is generally suitable for low-pressure dense phase conveying working conditions, the stability of carrier gas quantity is poor, a buffering process is not needed depending on opening of a switch, the powder spraying effect is poor, the particle size is different, the preparation of a preparation is influenced, the existing powder spraying operation is carried out, all switches are usually and directly closed in the stage of starting powder spraying and stopping powder spraying, the stability of the feed quantity and the air inflow is poor, the safety and stability of the powder spraying process are difficult to ensure, a large amount of materials are wasted, in addition, the working state of a nozzle is directly influenced by the gas carrying quantity and the feed quantity of the powder spraying device, once the flow is unstable, the nozzle is covered by solidified solid materials, a feed pipeline is blocked, the service life of the nozzle is shortened, the trouble is caused to subsequent treatment, and even huge economic loss is caused;
therefore, a powder spraying device for solid pharmaceutical excipients is needed.
Disclosure of Invention
The utility model provides a powder spraying device for solid pharmaceutical excipients, which solves the problems of easy blockage and poor service life of a nozzle in the prior art.
The technical scheme of the utility model is realized as follows:
the utility model provides a powder spraying device of solid pharmaceutical excipients, includes the inlet pipe, the discharge gate intercommunication of inlet pipe has the powder spraying tower, the discharge gate of powder spraying tower sets up to interior little big outer flat horn nozzle, set up gas cross flow board in the powder spraying tower, the one end of powder spraying tower is provided with the vibration sieve, liquid passes through the inlet pipe enters into in the powder spraying tower, form solid powder granule in the powder spraying tower, the different size granule of vibration sieve screening.
As a preferred embodiment, a separator is arranged between the powder spraying tower and the oscillating screen, and a discharge valve is arranged between the powder spraying tower and the separator.
As a preferred embodiment, the discharge valve is a star-shaped rotary valve.
As a preferred embodiment, one end of the separator is communicated with a dust removing bin.
As a preferred implementation mode, the separator is provided with a gas-solid separator, and the gas outlet of the gas-solid separator is communicated with a carrier gas source.
As a preferable implementation mode, the air outlet end of the separator is connected with a surface cooler, and the inlet end of the surface cooler is connected with the air outlet end of the dust removal bin.
As a preferred implementation mode, the oscillating screen is provided with a plurality of layers of screen plates, and the pore diameters of the screen plates are sequentially reduced from top to bottom and are used for obtaining finished products of the medicinal auxiliary materials with different particle diameters.
As a preferred embodiment, the feeding pipe is provided with a booster pump and a regulating valve.
After the technical scheme is adopted, the utility model has the beneficial effects that: the powder and air flow sprayed from the powder spraying device are stable in state, good in powder spraying effect, applicable to complex working conditions, applicable to working conditions of liquid medicinal auxiliary material powder preparation process, material-saving, cost-reducing and powder spraying efficiency-improving;
(2) The powder spraying tower adopts the flat horn-shaped nozzle with the small inside and the large outside, so that the pharmaceutic adjuvant in a liquid state is sprayed out in a fan shape, and compared with round openings and square openings on the market, the contact area of the liquid material and carrier gas is effectively increased, the agglomeration phenomenon is reduced, and the qualification rate of finished products is improved;
(3) The powder spraying tower is internally provided with the gas cross flow plate, when the flow of the carrier gas changes, a certain buffer effect is provided, when the opening of the carrier gas switch changes, the powder flow is prevented from suddenly and greatly fluctuating, the air flow stability is improved, and the powder spraying stability is further ensured.
Drawings
In order to more clearly illustrate the embodiments of the utility model or the technical solutions of the prior art, the drawings which are used in the description of the embodiments or the prior art will be briefly described, it being obvious that the drawings in the description below are only some embodiments of the utility model, and that other drawings can be obtained according to these drawings without inventive faculty for a person skilled in the art.
FIG. 1 is a front view of the present utility model;
FIG. 2 is a cross-sectional view of a powder spray tower according to the present utility model.
In the figure, 1, a feed pipe; 2. a powder spraying tower; 3. a separator; 4. a gas cross-flow plate; 5. a dust removal bin; 6. a gas-solid separator; 7. a surface cooler; 8. a booster pump; 9. a regulating valve; 10. a vibrating screen; 11. a discharging valve; 13. a carrier gas source.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Examples:
as shown in fig. 1-2, a powder spraying device for solid pharmaceutical excipients comprises a powder spraying tower 2, wherein a feed inlet of the powder spraying tower 2 is provided with a feed pipe 1, a booster pump 8 and a regulating valve 9 are arranged on the feed pipe 1, the booster pump 8 and the regulating valve 9 are opened, a worker conveys liquid raw materials into the powder spraying tower 2 through the feed pipe 1, the liquid forms powdery solid in the powder spraying tower 2, wherein a discharge outlet of the powder spraying tower 2 adopts a flat horn-shaped nozzle with a small inside and a large outside, so that the pharmaceutical excipients in a liquid state are sprayed out in a fan shape, compared with round openings and square openings in the market, the contact area of the liquid materials and carrier gas is effectively increased, the agglomeration phenomenon is reduced, the yield is improved, and when the carrier gas flow is changed, a certain buffer effect is provided, the sudden fluctuation of the powder flow is prevented when the opening degree of a carrier gas switch is changed, the air flow stability is improved, and the powder spraying stability is further ensured;
in the embodiment, a separator 3 is arranged at a discharge hole of a powder spraying tower 2, a discharge valve 11 is arranged between the separator 3 and the powder spraying tower 2, wherein the discharge valve 11 is a star-shaped rotary valve, the discharge valve 11 is opened, processed powder enters the separator 3, powder and gas are separated in the separator 3, a dust removal bin 5 is arranged at one side of the separator 3, some large powder which cannot be recycled and generated by the separator 3 enters the dust removal bin 5, and after the dust removal bin 5 is filled with the powder, staff clean the powder;
in the embodiment, a vibrating screen 10 is arranged at a powder outlet of a separator 3, the aperture of a screen plate of the vibrating screen 10 is sequentially reduced from top to bottom, a plurality of layers of screens are arranged on the vibrating screen 10 and are used for obtaining finished products of medicinal auxiliary materials with different particle sizes, the outlet ends of the vibrating screen are respectively connected with a plurality of powder bins, and separated solid medicines are respectively stored in the powder bins corresponding to the vibrating screen;
in the embodiment, a gas-solid separator 6 is arranged at a gas outlet of the separator 3, some powder with gas enters the gas-solid separator 6, the gas and the powder are separated by the gas-solid separator 6, a carrier gas source 13 is arranged at one side of the gas-solid separator 6, and the separated gas enters the carrier gas source 13 for storage;
the surface cooler 7 is arranged between the gas-solid separator 6 and the cyclone separator 3, the surface cooler 7 displays data such as flow and the like for workers to watch, moreover, the air outlet end of the dust removal bin 5 is connected with the inlet end of the surface cooler 7, and the surface cooler 7 also displays working data of the dust removal bin 5;
the utility model comprises the following operation steps:
powder adding process: opening a carrier gas source 13, the separator 3 and the dust removal bin 5, regulating an airflow regulating valve 9 of the carrier gas source 13 and the separator 3 to be in a low flow mode, and opening a liquid material booster pump 8 when the constant pressure is lower than 0.05MPa for ten seconds;
and (3) powder spraying: opening a feeding regulating valve 9 and a discharging valve 11, and enabling the feeding regulating valve 9 to be at a minimum opening (5-20%) and the discharging valve to be in a low flow mode; measuring whether the powder spraying of the powder spraying tower 2 is normal powder discharging, if so, increasing the opening of the feeding regulating valve 9 and the discharging valve 11 (which are 2-5% larger than the minimum opening) to spray the powder;
stopping the powder: slowly reducing the opening of the feeding regulating valve 9 to be closed, increasing the opening of the airflow regulating valve 9 and the opening of the discharging valve 11, and ending powder spraying, wherein the working time is at least 5 seconds;
in the powder spraying process, if abnormal powder discharge of the powder spraying tower 2 is detected, repeatedly adjusting the feeding adjusting valve 9, the air flow adjusting valve 9 and the discharging valve 11 until the powder discharge is normal;
the foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the utility model.
Claims (8)
1. The utility model provides a powder spraying device of solid pharmaceutical excipients, its characterized in that, including inlet pipe (1), the discharge gate intercommunication of inlet pipe (1) has powder spraying tower (2), the discharge gate of powder spraying tower (2) sets up to interior little big flat horn nozzle outward, set up gaseous cross flow board (4) in powder spraying tower (2), the one end of powder spraying tower (2) is provided with vibration sieve (10), liquid is through inlet pipe (1) enters into in powder spraying tower (2), form solid powder form granule in powder spraying tower (2), vibration sieve (10) sieve not unidimensional granule.
2. The powder spraying device of solid pharmaceutical excipients according to claim 1, wherein: a separator (3) is arranged between the powder spraying tower (2) and the oscillating screen (10), and a discharging valve (11) is arranged between the powder spraying tower (2) and the separator (3).
3. The powder spraying device of solid pharmaceutical excipients according to claim 2, wherein: the discharging valve (11) is a star-shaped rotary valve.
4. The powder spraying device of solid pharmaceutical excipients according to claim 2, wherein: one end of the separator (3) is communicated with a dust removal bin (5).
5. The powder spraying device of solid pharmaceutical excipients according to claim 2, wherein: the gas-solid separator (6) is arranged on the separator (3), and a gas outlet of the gas-solid separator (6) is communicated with a carrier gas source (13).
6. The powder spraying device of solid pharmaceutical excipients according to claim 4, wherein: the air outlet end of the separator (3) is connected with a surface cooler (7), and the inlet end of the surface cooler (7) is connected with the air outlet end of the dust removal bin (5).
7. The powder spraying device of solid pharmaceutical excipients according to claim 1, wherein: the oscillating screen (10) is provided with a plurality of layers of screen plates, the pore diameters of the screen plates are sequentially reduced from top to bottom, and the oscillating screen is used for obtaining finished products of medicinal auxiliary materials with different particle diameters.
8. The powder spraying device of solid pharmaceutical excipients according to claim 1, wherein: the feeding pipe (1) is provided with a booster pump (8) and a regulating valve (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321031738.5U CN220546586U (en) | 2023-04-28 | 2023-04-28 | Powder spraying device for solid pharmaceutical auxiliary materials |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321031738.5U CN220546586U (en) | 2023-04-28 | 2023-04-28 | Powder spraying device for solid pharmaceutical auxiliary materials |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220546586U true CN220546586U (en) | 2024-03-01 |
Family
ID=90004647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321031738.5U Active CN220546586U (en) | 2023-04-28 | 2023-04-28 | Powder spraying device for solid pharmaceutical auxiliary materials |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220546586U (en) |
-
2023
- 2023-04-28 CN CN202321031738.5U patent/CN220546586U/en active Active
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